Cardiovascular risk factors are associated with lower posterior-medial network functional connectivity in older adults

Cardiovascular risk factors are associated with lower posterior-medial network functional connectivity in older adults

Abstract Background Cortico-hippocampal functional networks, specifically the anterior-temporal (AT) and posterior-medial (PM) systems, are crucial for memory and highly vulnerable to aging and Alzheimer’s disease (AD). While modifiable cardiovascular risk factors may offer prevention opportunities...

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Main Authors: Léa Chauveau, Julie Gonneaud, Géraldine Poisnel, Brigitte Landeau, Antoine Garnier-Crussard, Anne-Lise Pitel, Daniel Roquet, Edelweiss Touron, Sacha Haudry, Florence Mezenge, Anne Chocat, Denis Vivien, Vincent de La Sayette, Gaël Chételat, Robin de Flores, for the Medit-Ageing Research Group
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Medial temporal lobe
Aging
Functional connectivity
Cardiovascular risk factors
Functional magnetic resonance imaging
Aslzheimer’s disease
Online Access:https://doi.org/10.1186/s13195-025-01808-5
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https://doi.org/10.1186/s13195-025-01808-5

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