Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis
IntroductionDental caries is a prevalent oral disease with a multifactorial etiology. Lactobacillus has been implicated in caries progression on account of its acidogenic properties; On the other hand, they constitute one of the potential probiotic strategies for preventing dental caries. This compl...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oral Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/froh.2025.1535233/full |
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| author | Di Fu Xingyue Shu Lin Yao Ge Zhou Mengzhen Ji Ga Liao Yunwo Zhu Ling Zou |
| author_facet | Di Fu Xingyue Shu Lin Yao Ge Zhou Mengzhen Ji Ga Liao Yunwo Zhu Ling Zou |
| author_sort | Di Fu |
| collection | DOAJ |
| description | IntroductionDental caries is a prevalent oral disease with a multifactorial etiology. Lactobacillus has been implicated in caries progression on account of its acidogenic properties; On the other hand, they constitute one of the potential probiotic strategies for preventing dental caries. This complex relationship renders the relationship between Lactobacillus and dental caries remains ambiguous.MethodsThe Web of Science core collections (WoSCC) were searched to acquire articles relevant to Lactobacillus and dental caries. After retrieval and manual screening, publications were analyzed by VOSviewer.ResultsSweden, the US, and China, which have been the center of international cooperation, have produced the most publications in the research area. Caries Research is the main counterpart journal in the field. “Dental caries”, “Streptococcus mutans”, “Lactobacilli”, “Probiotics”, and “Children” have been commonly used as keywords.DiscussionBased on bibliometric analysis, this study reviews the relationship between lactobacilli and dental caries, emphasizing their dual roles. The detection rate of lactobacilli is closely associated with the incidence and severity of dental caries. However, under specific environmental conditions, these bacteria also exhibit potential probiotic properties that may aid in the prevention of dental caries. Additionally, Lactobacillus is strongly associated with early childhood caries, a specific type of caries. |
| format | Article |
| id | doaj-art-012265ca7f074b40b3d78f99e8c7e85b |
| institution | Kabale University |
| issn | 2673-4842 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oral Health |
| spelling | doaj-art-012265ca7f074b40b3d78f99e8c7e85b2025-01-31T06:41:10ZengFrontiers Media S.A.Frontiers in Oral Health2673-48422025-01-01610.3389/froh.2025.15352331535233Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysisDi Fu0Xingyue Shu1Lin Yao2Ge Zhou3Mengzhen Ji4Ga Liao5Yunwo Zhu6Ling Zou7State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Information Management, Department of Stomatology Informatics, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Geriatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, ChinaIntroductionDental caries is a prevalent oral disease with a multifactorial etiology. Lactobacillus has been implicated in caries progression on account of its acidogenic properties; On the other hand, they constitute one of the potential probiotic strategies for preventing dental caries. This complex relationship renders the relationship between Lactobacillus and dental caries remains ambiguous.MethodsThe Web of Science core collections (WoSCC) were searched to acquire articles relevant to Lactobacillus and dental caries. After retrieval and manual screening, publications were analyzed by VOSviewer.ResultsSweden, the US, and China, which have been the center of international cooperation, have produced the most publications in the research area. Caries Research is the main counterpart journal in the field. “Dental caries”, “Streptococcus mutans”, “Lactobacilli”, “Probiotics”, and “Children” have been commonly used as keywords.DiscussionBased on bibliometric analysis, this study reviews the relationship between lactobacilli and dental caries, emphasizing their dual roles. The detection rate of lactobacilli is closely associated with the incidence and severity of dental caries. However, under specific environmental conditions, these bacteria also exhibit potential probiotic properties that may aid in the prevention of dental caries. Additionally, Lactobacillus is strongly associated with early childhood caries, a specific type of caries.https://www.frontiersin.org/articles/10.3389/froh.2025.1535233/fulllactobacillidental cariescariogenicityprobioticscaries preventionearly childhood caries |
| spellingShingle | Di Fu Xingyue Shu Lin Yao Ge Zhou Mengzhen Ji Ga Liao Yunwo Zhu Ling Zou Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis Frontiers in Oral Health lactobacilli dental caries cariogenicity probiotics caries prevention early childhood caries |
| title | Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis |
| title_full | Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis |
| title_fullStr | Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis |
| title_full_unstemmed | Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis |
| title_short | Unveiling the dual nature of Lactobacillus: from cariogenic threat to probiotic protector—a critical review with bibliometric analysis |
| title_sort | unveiling the dual nature of lactobacillus from cariogenic threat to probiotic protector a critical review with bibliometric analysis |
| topic | lactobacilli dental caries cariogenicity probiotics caries prevention early childhood caries |
| url | https://www.frontiersin.org/articles/10.3389/froh.2025.1535233/full |
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