Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis
Background. Aim was to elucidate the role of toll-like receptor 9 (TLR9) in cardiac inflammation and septic heart failure in a murine model of polymicrobial sepsis. Methods. Sepsis was induced via colon ascendens stent peritonitis (CASP) in C57BL/6 wild-type (WT) and TLR9-deficient (TLR9-D) mice. Ba...
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Main Authors: | Ralph Lohner, Markus Schwederski, Carolin Narath, Johanna Klein, Georg D. Duerr, Alexandra Torno, Pascal Knuefermann, Andreas Hoeft, Georg Baumgarten, Rainer Meyer, Olaf Boehm |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2013/261049 |
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