Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel Burkholderia-derived alkaloid

Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel Burkholderia-derived alkaloid

ABSTRACT Biofilms are an important colonization mechanism employed by several microbial species to better establish themselves and monopolize the acquisition of resources across different environs. Some bacteria have evolved specialized metabolites that, when secreted, disrupt the formation and stab...

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Main Authors: McKinley D. Williams, Taylor R. Sweeney, Sabrina Trieu, Ravi Orugunty, Abdelahhad Barbour, Fereshteh Younesi, Michael Glogauer, Nopakorn Hansanant, Ronald Shin, Shi-En Lu, Kevin Cao, Abraham Tenorio, Sigmund J. Haidacher, Anthony M. Haag, Thomas D. Horvath, Leif Smith
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
Subjects:
biofilm
Burkholderia
antibacterial
antimicrobial resistance
metabolite
quinolone
Online Access:https://journals.asm.org/doi/10.1128/msphere.01081-24
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https://journals.asm.org/doi/10.1128/msphere.01081-24

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