The effect of Polybrominated diphenyl ethers at the fetal blood-brain-barrier: evaluation using a microphysiological system

BackgroundGlutamate dysregulation leading to neuronal excitotoxicity and neuroinflammation are associated with neurological disorders, specifically autism spectrum disorders (ASD) in preterm neonates. The lack of physiologically relevant in vitro models has limited mechanistic understanding of gluta...

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Main Authors: Sourabh Sharma, Manuel Vidal, Souvik Paul, Arum Han, Ramkumar Menon, Lauren S. Richardson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1543710/full
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