An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores

Parkinson’s disease (PD) is the second most common, neurodegenerative disorder. It is a chronic, disabling, and progressive disease, and no treatment stops its progression. Rating scales are utilized to quantify PD progression and severity. The most conventional scale is the Unified Parkinson’s Dise...

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Main Authors: Renee M. Hendricks, Mohammad T. Khasawneh
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2021/1765220
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author Renee M. Hendricks
Mohammad T. Khasawneh
author_facet Renee M. Hendricks
Mohammad T. Khasawneh
author_sort Renee M. Hendricks
collection DOAJ
description Parkinson’s disease (PD) is the second most common, neurodegenerative disorder. It is a chronic, disabling, and progressive disease, and no treatment stops its progression. Rating scales are utilized to quantify PD progression and severity. The most conventional scale is the Unified Parkinson’s Disease Rating Scale (UPDRS) and its modified version, Movement Disorder Society- (MDS-) UPDRS. An analytical investigation into the use and meaning of these clinical scale scores was conducted to determine if gaps exist in quantifying disease progression and severity. A series of discrepancies were identified including confusion among patients regarding the score meaning and misuse of the scores among clinicians and researchers to define disease progression. The scales are of an ordinal type and hence the resulting scores are ordinal, not providing a quantifiable progression nor severity level, but a categorical value and survey total. The knowledge that the scores are ordinal and the scales are subjective is mentioned in very limited publications, not the focus of these papers, but a brief introduction and a thoroughly researched, analytical investigation into the scales and scores have not been found. Therefore, the continuous misunderstanding and misuse of these scales and resulting scores warrant a comprehensive assessment and evaluation of these scales and scores to identify the gaps.
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spelling doaj-art-00b6855e10a1471da57c31ccca19f2cc2025-02-03T01:25:26ZengWileyParkinson's Disease2090-80832042-00802021-01-01202110.1155/2021/17652201765220An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale ScoresRenee M. Hendricks0Mohammad T. Khasawneh1Department of Systems Science and Industrial Engineering, Binghamton University, P.O. Box 6000, Binghamton, NY 13902-6000, USADepartment of Systems Science and Industrial Engineering, Binghamton University, P.O. Box 6000, Binghamton, NY 13902-6000, USAParkinson’s disease (PD) is the second most common, neurodegenerative disorder. It is a chronic, disabling, and progressive disease, and no treatment stops its progression. Rating scales are utilized to quantify PD progression and severity. The most conventional scale is the Unified Parkinson’s Disease Rating Scale (UPDRS) and its modified version, Movement Disorder Society- (MDS-) UPDRS. An analytical investigation into the use and meaning of these clinical scale scores was conducted to determine if gaps exist in quantifying disease progression and severity. A series of discrepancies were identified including confusion among patients regarding the score meaning and misuse of the scores among clinicians and researchers to define disease progression. The scales are of an ordinal type and hence the resulting scores are ordinal, not providing a quantifiable progression nor severity level, but a categorical value and survey total. The knowledge that the scores are ordinal and the scales are subjective is mentioned in very limited publications, not the focus of these papers, but a brief introduction and a thoroughly researched, analytical investigation into the scales and scores have not been found. Therefore, the continuous misunderstanding and misuse of these scales and resulting scores warrant a comprehensive assessment and evaluation of these scales and scores to identify the gaps.http://dx.doi.org/10.1155/2021/1765220
spellingShingle Renee M. Hendricks
Mohammad T. Khasawneh
An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
Parkinson's Disease
title An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
title_full An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
title_fullStr An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
title_full_unstemmed An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
title_short An Investigation into the Use and Meaning of Parkinson’s Disease Clinical Scale Scores
title_sort investigation into the use and meaning of parkinson s disease clinical scale scores
url http://dx.doi.org/10.1155/2021/1765220
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