Uncovering the epigenetic regulatory clues of PRRT1 in Alzheimer’s disease: a strategy integrating multi-omics analysis with explainable machine learning

Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a largely unexplored epigenetic landscape. Objective This study employs an innovative approach that integrates multi-omics analysis and explainable machine learning to explore the epigenetic regulatory mechanis...

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Bibliographic Details
Main Authors: Fang Wang, Ying Liang, Qin-Wen Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13195-024-01646-x
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