MiR-200c synergizes with trastuzumab-loaded gold nanoparticles to overcome resistance in ovarian cancer cells

MiR-200c synergizes with trastuzumab-loaded gold nanoparticles to overcome resistance in ovarian cancer cells

Abstract Background Trastuzumab (TZ) resistance remains a significant challenge in the treatment of human epidermal growth factor receptor 2 (HER2)-positive epithelial ovarian cancer (EOC), necessitating novel therapeutic strategies to improve treatment efficacy. Functionalized gold nanoparticles (A...

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Main Authors: Tommaso A. Salamone, Sofia Marotta, Stella Mrmić, Salvatore Raffa, Sara Cerra, Beatrice Pennacchi, Martina Mercurio, Vincenzo Visco, Maurizio Alimandi, Maria Rosaria Ricciardi, Maurizio Taurino, Ilaria Fratoddi, Pankaj Trivedi, Eleni Anastasiadou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Nanotechnology
Subjects:
Trastuzumab
HER2
AuNPs
MicroRNA
Ovarian cancer
Drug delivery
Online Access:https://doi.org/10.1186/s12645-025-00330-5
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https://doi.org/10.1186/s12645-025-00330-5

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