Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

Abstract Aspergillus fumigatus, which causes aspergillosis, has developed resistance to azole antifungal agents in recent years. As only three main classes of antifungal drugs are available, the development of novel therapeutic strategies is crucial. We aimed to control the expression of virulence f...

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Bibliographic Details
Main Authors: Tatsuya Inukai, Rikuto Watanabe, Yoshiki Murakami, Horacio Cabral, Masahiko Kuroda, Shigeki Nakamura
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-02742-0
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