Ginsenoside Rg1 regulating inflammatory response and bone-remodeling through Keap1/Nrf2 signaling pathway in rats with periodontitis

Ginsenoside Rg1 regulating inflammatory response and bone-remodeling through Keap1/Nrf2 signaling pathway in rats with periodontitis

Abstract Periodontitis is a chronic inflammatory disease arising from local microorganisms and the host’s own aberrant immune regulation. Ginsenoside Rg1(GS-Rg1) is an active extract of ginseng known for its anti-inflammatory and osteogenesis effects. However, GS-Rg1 has not been shown to treat peri...

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Bibliographic Details
Main Authors: Yang Zhou, Yunan Zhang, Li Wang, Youbo Liu, Zhongke Wang, Ling Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Periodontitis
GS-Rg1
Inflammatory response
Alveolar bone remodelling
Keap1/Nrf2 signalling pathway
Online Access:https://doi.org/10.1038/s41598-025-92165-8
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https://doi.org/10.1038/s41598-025-92165-8

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