Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

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The association between visceral fat metabolic score and stroke: mediation by declining kidney function by Yue Cao, Weixing Wen, Hao Zhang, Weiwen Li, Guolin Huang, Yuli Huang

“…Subgroup analysis indicated that the association was stronger in men (OR = 5.06, 95% CI: 2.80–9.12, P < 0.001) than in women (OR = 2.01, 95% CI: 1.03–3.92, P = 0.04, P for interaction = 0.01). …”
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Identification of mitophagy-related biomarkers and immune infiltration in polycystic ovarian syndrome by bioinformatic study by Hongjuan Ye, Xicheng Wang, Zhiying He

“…Background: Polycystic ovarian syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. In this study, we aimed to investigate the potential prognostic value of mitophagy-related genes in PCOS patients and to analyze their role in immune infiltration during PCOS pathogenesis and progression. …”
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Elritercept, a modified activin receptor IIA ligand trap, increased erythropoiesis and thrombopoiesis in a phase 1 trial by Jennifer Lachey, Christopher Rovaldi, Suresh Bobba, Jared Tur, Harveen Natarajan, Ben Snyder, Jasbir Seehra

“…The objectives of this phase 1 randomized, placebo-controlled study of elritercept were to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic markers of activin inhibition and hematopoiesis in healthy postmenopausal women (N = 48). This study comprised 2 parts: single ascending doses ranging from 0.05 to 4.5 mg/kg; and multiple (up to 2 doses) ascending doses of 0.75 mg/kg administered subcutaneously (SC) every 4 weeks. …”
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Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms by Chiara Cattaneo, Alice Caramaschi, Elena Uga, Michela Braghin, Gianluca Cosi, Chiara Peila, Maria C. Strozzi, Miriam Sabatini, Diego Gazzolo, Marcello Manfredi, Maria Cavaletto

“…Here, we investigated the presence of Toll-like receptors TLR1/2/4/6 in colostrum and mature milk of women who delivered before (preterm) or after (term) 37 weeks of gestational age, integrating classical immune-related techniques with proteomic LC-MS/MS analysis. …”
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Patient Perspectives on Engagement in Recovery after Hip Fracture: A Qualitative Study by Joanie Sims-Gould, Sarah Stott-Eveneshen, Lena Fleig, Megan McAllister, Maureen C. Ashe

“…Method. 50 community-dwelling older adults recovering from a recent (3–12 months) hip fracture (32 women, 18 men) participated in telephone interviews using a semistructured format at 6 and 12 months after recruitment into the study. …”
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Pregnancy after kidney and liver transplantation by A Wise, N E Diana, B Bobat, R T Saggers, S Bhoora, S Budhram, L Chauke, V G Lala, A Mahomed, D Mokgoko, M Seabi, B Moore, S Naidoo, R B Nyakoe, N Odell, G Paget, L Wium, J Zamparini

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Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling by Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang

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Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands by Wanderson Ferreira da Silva Júnior, Karen Marques de Oliveira Costa, Hortência Maciel Castro Oliveira, Maísa Mota Antunes, Kassiana Mafra, Brenda Naemi Nakagaki, Pedro Sérgio Corradi da Silva, Júlia Duarte Megale, Sarah Campos de Sales, Douglas Carvalho Caixeta, Mário Machado Martins, Robinson Sabino-Silva, Cristina Maria Pinto de Paula, Luiz Ricardo Goulart, Rafael Machado Rezende, Gustavo Batista Menezes

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Impact of maternal prenatal stress by glucocorticoids on metabolic and cardiovascular outcomes in their offspring: A systematic scoping review. by Claudia Eberle, Teresa Fasig, Franziska Brüseke, Stefanie Stichling

“…<h4>Results</h4>Overall, n = 2.634 citations were identified, n = 45 eligible studies were included and synthesized according to their key findings. …”
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Spatio-temporal distribution of Dengue, Zika and Chikungunya in Cali, Colombia: 2014-2016 by José F. Fuertes-Bucheli, Gladys Pérez-Arizabaleta, Andrea Quiroz-Caicedo, Robin A. Olaya, Hoover O. León-Giraldo, Robinson Pacheco-López

“…Results: 40,168 cases were analyzed, and it was found that dengue was the most frequent arboviral infection (59.2 %). The most affected individuals were women (65 %) and those with a mean age of 34.5 years. …”
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Cytokines in Liver Cirrhosis (Their Importance in Assessing Activity and Decompensation) by G. K. Mirodzhov, S. D. Pulatova

“…In liver cirrhosis, there is a significant disruption in the synthesis of pro-inflammatory cytokines, which is manifested by a sharp increase in the content of TNF-α, interleukin-2 and interleukin-6. High levels of proinflammatory cytokines in blood serum in liver cirrhosis correlate with the activity and degree of decompensation, which indicates their important role in the pathogenesis and progression of the pathological process.…”
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Decreased Expression of GPER1 Gene and Protein in Goiter by Raquel Weber, Ana Paula Santin Bertoni, Laura Walter Bessestil, Ilma Simoni Brum, Tania Weber Furlanetto

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Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms by Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu

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Impetus of US hospital leaders to invest in patient-reported outcome measures (PROMs): a qualitative study by Andrea L Pusic, Marilyn Heng, Danny Mou, Rachel C Sisodia, Meredith B Rosenthal, Barbara Bokhour, Christer Mjåset, Claire M Sokas, Azan Virji

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Evaluation of the Nutrition Heart Program Through the Four Elements of Community Empowerment Approach by Rika Satyadewi, Galuh Mega Kurnia, Arina Mufida Ersanti, Corie Indria Prasasti

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The clinical application of artificial intelligence in cancer precision treatment by Jinyu Wang, Ziyi Zeng, Zehua Li, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao

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Determinants of Malaria Prevention and Treatment Seeking Behaviours of Pregnant Undergraduates Resident in University Hostels, South-East Nigeria by Anthonia Ukamaka Chinweuba, Noreen Ebelechukwu Agbapuonwu, JaneLovena Enuma Onyiapat, Chidimma Egbichi Israel, Clementine Ifeyinwa Ilo, Joyce Chinenye Arinze

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Maternal Serum Fractalkine Concentrations in Pregnancies Complicated by Fetal Growth Restriction by Ecem Berfun Toprak Sager, Ibrahim Kale, Hakan Sager, Aysegul Ozel, Murat Muhcu

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DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis by Leilei Xia, Ye Wang, Shengyun Cai, Mingjuan Xu

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