Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure by Rima Kamel, Aurélia Bourcier, Jean Piero Margaria, Valentin Jin, Audrey Varin, Agnès Hivonnait, Françoise Mercier‐Nomé, Delphine Mika, Alessandra Ghigo, Flavien Charpentier, Vincent Algalarrondo, Emilio Hirsch, Rodolphe Fischmeister, Grégoire Vandecasteele, Jérôme Leroy

“…However, increased PDE2A blunted these adverse outcomes evoked by sympathomimetic amines. Conclusions Cardiac gene therapy with PDE2A limits left ventricle remodeling, dysfunction, and arrhythmias evoked by catecholamines, providing evidence that increasing PDE2A activity acutely could prevent progression toward heart failure.…”
Get full text

Metabolome profiling dissects the oat (Avena sativa L.) innate immune response to Pseudomonas syringae pathovars. by Chanel J Pretorius, Paul A Steenkamp, Ian A Dubery

“…Metabolic profiles derived from further multivariate data analyses revealed a range of metabolite classes involved in the respective defence responses, including fatty acids, amino acids, phenolic acids and phenolic amides, flavonoids, saponins, and alkaloids. The findings in this study allowed the elucidation of metabolic changes involved in oat defence responses to a range of pathovars of P. syringae and ultimately contribute to a more comprehensive view of the oat plant metabolism under biotic stress during host vs nonhost interactions.…”
Get full text

Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…We noticed that biochemical and pathological changes corresponded to the infrared (IR) peaks at 1545 cm-1 and 1511 cm-1 (amide II), 1246 cm-1 (DNA/RNA phosphate backbones), and 1181 cm-1 (C–O vibrations). …”
Get full text

Experimental Solution of Chitosan and Nanochitosan on Wettability in Root Dentine: In Vitro Model Prior Regenerative Endodontics by Fernando Arias Alvarado, Maira Rivero Iriarte, Freddy Jordan Mariño, Sara Quijano-Guauque, León D. Pérez, Yolima Baena, Claudia García-Guerrero

“…The wettability analysis calculated the contact angle (θ) between a drop of a blood-like and root dentinal surface; topographic characterization with scanning electron microscopy (SEM) quantified the diameter and number of tubules per area; spectroscopy infrared analyses (IR-S) identified chemical changes in the inorganic (phosphate/carbonate) and organic phase (amide/methyl). Statistical analysis: a linear mixed model, Kruskal–Wallis, and Holm–Bonferroni correction (P < 0.05) were used. …”
Get full text

Chitosan-multilayered graphene oxide hybrid beads for $\protect \text{Zn}^{2+}$ and metoprolol adsorption by Bouyahmed, Farida, Muller, Fabrice, Richard, Annie, Mostefaoui, Toufik Amayas, Belabbas, Imad, Warmont, Fabienne, Roulet, Marjorie, Reinert, Laurence, Duclaux, Laurent, Delpeux-Ouldriane, Sandrine

“…The presence of $\text{Zn}^{2+}$ adsorption sites in the hybrid bead, such as MGO carboxylate groups giving electrostatic interactions, and CS amine groups leading to complexation, provides synergic adsorption effects. …”
Get full text

Evaluación comparativa de herramientas tecnológicas basadas en Inteligencia Artificial para el monitoreo de enfermedades by Oscar Efrén Cárdenas Villavicencio, Milton Rafael Valarezo Pardo, Freddy Aníbal Jumbo Castillo, Juan Andrés Jaramillo Barreiro

“…Estos incluyen: respuestas rápidas e instantáneas, interfaz amigable y sencilla, adaptabilidad Lingüística, integración con Registros Médicos Electrónicos (EMR) y seguridad de Datos, garantizando la confidencialidad y protección de la información del paciente.…”
Get full text

Yugoslavya’dan Türkiye’ye Göçlerin Nedenleri 1950-1958 by Cemile Tekin

“…Osmanlı döneminde “Müslümanlar”ın, Cumhuriyet döneminde ise “Türk soyundan olan veya Türk kültürüne bağlı bulunanların”, Türkiye’ye Balkanlar’dan zorunlu göçlerinin başlıca benimsenen nedenleri; soykırımlar, saldırılar, harpler, yağmalar, baskı ve ayrımlar, sürgünler ve zorla asimilasyonlar, açıkçası cana, mala, namusa, dinî veya millî kimliğe saldırılardır. Yukarıdaki amiller dolayısıyla göç hareketlerine sahne olunan bölgelerden biri de Balkanlar’daki “Yugoslavya-Makedonya” topraklarıdır. …”
Get full text

Chitosan-DNA nanoparticles: synthesis and optimization for long-term storage and effective delivery by Aigul Raimbekova, Ulpan Kart, Akbayan Yerishova, Timur Elebessov, Sergey Yegorov, Tri Thanh Pham, Gonzalo Hortelano

“…Results DLS and TEM analysis indicated amine groups on chitosan to phosphate groups on DNA (N:P) ratios yielded smaller CsNPs sizes. …”
Get full text

Assessment of Tuber Yield Stability and Adaptability of Some Elite Yam Genotypes in the Guinea Savannah Ecology of Northern Ghana by Joseph Adjebeng-Danquah, Kwabena Acheremu, Emmanuel Boachie Chamba, Freda Ansaah Agyapong, Alhassan Sayibu

“…According to the additive main effect multiplicative interaction (AMMI) analysis, genotype (G), environment (E), and GxE interaction, respectively, explained 39.71%, 36.03%, and 24.26% of the total sum of squares for tuber yield. …”
Get full text

Shedding light on biochemical changes in single neuron-like pheochromocytoma cells following exposure to synchrotron sourced terahertz radiation using synchrotron source Fourier tr... by Palalle G. Tharushi Perera, Jitraporn Vongsvivut, Denver Linklater, Zoltan Vilagosh, Dominique Appadoo, The Hong Phong Nguyen, Mark J. Tobin, Rodney Croft, Elena P. Ivanova

“…According to the PCA loadings, the key changes in the exposed cells involved lipid and protein compositions as indicated by the stretching vibrations of CH2/CH3 groups and amide I/II bands, respectively. An increase in lipids, such as cholesterol, or notable changes in their compositions and in some protein secondary structures were observed in the SS THz-exposed cells. …”
Get full text

Navigating Patient Satisfaction: A Qualitative Insight into Healthcare Delivery during the COVID-19 Pandemic by Shazina Saeed, Manmohan Singhal, Mohd Shannawaz, Mandeep Kumar Arora

“…Ethical clearance was obtained from the Institutional Ethics Committee of Amity University (AUUP/IEC/2023/4). Thematic analysis was conducted to identify common themes and insights regarding patient satisfaction. …”
Get full text

Use of Plackett–Burman Statistical Design to Study Factors Acting on the Nitric Acid Leaching of Rare Earth Elements from Moroccan Phosphogypsum by Fatima Asafar, Marouane Amine, Abdelkader Outzourhit, Latifa Bilali, Mehdi Nadifiyine

“…The optimal experimental conditions are a nitric acid concentration of 3.3 M, a solid-to-liquid ratio of 1/9, a temperature of 75°C, a leaching time of 20 min, a stirring speed of 200 rpm, and d ≤ 100 µm as a particle size.…”
Get full text

Analgesic, Antioxidant, Anti-Inflammatory, and Wound-Treating Actions of Bitter Apricot Kernel Extract by Mohamed Amine El-Hajjaji, Kawtar Fikri-Benbrahim, Najoua Soulo, Ghizlane Nouioura, Hassan Laaroussi, Pedro Ferreira-Santos, Badiaa Lyoussi, Zineb Benziane Ouaritini

Get full text

Impact of eye movements and facial expressions on social performance during a collaborative problem-solving task by Kana Miyamoto, Hiroki Tanaka, Jennifer Hamet Bagnou, Céline Clavel, Elise Prigent, Amine Benamara, Christine Le Scanff, Jean-Claude Martin, Satoshi Nakamura

Get full text

Reversible Myocarditis after Black Widow Spider Envenomation by Tarek Dendane, Khalid Abidi, Naoufel Madani, Asmae Benthami, Fatima-Zohra Gueddari, Redoune Abouqal, Amine-Ali Zeggwagh

Get full text

Acute effects of virtual reality exercise bike games on psychophysiological outcomes in college North-African adolescents with cerebral palsy: A randomized clinical trial [version... by Mehdi Chlif, Amine Ghram, Makrem Soudani, Faical Farhat, Helmi Ben Saad

Get full text

Diversity of aphids and their natural enemies in forest areas of northwestern Algeria, with a new record of Myzocallis schreiberi by Amine Akrich, Kada Righi, Fatiha Assia Righi, Abdelwahab Chedad, George Japoshivli

Get full text

A Discrete Mathematical Modeling and Optimal Control of the Rumor Propagation in Online Social Network by Amine El Bhih, Rachid Ghazzali, Soukaina Ben Rhila, Mostafa Rachik, Adil El Alami Laaroussi

Get full text

Knowledge, Attitude, and Practices (KAP) Regarding Meat Safety and Sanitation among Carcass Handlers Operating and Assessment of Bacteriological Quality of Meat Contact Surfaces at... by Mohammed Amine Bahir, Ikram Errachidi, Mouhssine Hemlali, Bouchaib Sarhane, Asmae Tantane, Alami Mohammed, Bouchra Belkadi, Abdelkarim Filali-Maltouf

Get full text

Machine learning techniques for IoT security: Current research and future vision with generative AI and large language models by Fatima Alwahedi, Alyazia Aldhaheri, Mohamed Amine Ferrag, Ammar Battah, Norbert Tihanyi

Get full text