Uptake and 4-week outcomes of an ‘opt-out’ smoking cessation referral strategy in a London-based lung cancer screening setting by Anthony Edey, Neal Navani, Kitty Chan, Graham Robinson, Janine Zylstra, Paul Robinson, Laura Green, Anand Devaraj, Jane Rowlands, Allan Hackshaw, Carolyn Horst, Arjun Nair, Sam M Janes, Kate Davies, Jeannie Eng, Mamta Ruparel, Samantha L Quaife, Jennifer L Dickson, Magali Taylor, Angshu Bhowmik, Hasti Robbie, Joseph Jacob, Laura Farrelly, Sophie Tisi, Tanya Patrick, Andrew Creamer, Helen Hall, Samanjit Hare, Jon Teague, Samuel M Janes, Esther Arthur-Darkwa, Thea Buchan, Stephen Ellis, Thomas Callender, Rachael Sarpong, John McCabe, Zaheer Mangera, Ethaar El-Emir, Terry O'Shaughnessy, Geoff Bellingan, Nick Screaton, Priyam Verghese, William M Ricketts, Vicky Bowyer, Kylie Gyertson, Fanta Bojang, Claire Levermore, Tania Anastasiadis, Ruth Prendecki, Amyn Bhamani, Malavika Suresh, Judy Airebamen, Alice Cotton, Kaylene Phua, Elodie Murali, Simranjit Mehta, Karen Parry-Billings, Columbus Ife, April Neville, Zahra Hanif, Helen Kiconco, Ricardo McEwen, Dominique Arancon, Nicholas Beech, Derya Ovayolu, Christine Hosein, Sylvia Patricia Enes, Qin April Neville, Aashna Samson, Urja Patel, Fahmida Hoque, Hina Pervez, Sofia Nnorom, Moksud Miah, Julian McKee, Mark Clark, Anant Patel, Sara Lock, Rajesh Banka, Ugo Ekeowa, Charlotte Cash, Tunku Aziz, Alberto Villanueva, Elena Stefan, Charlie Sayer, Navinah Nundlall, Andrew Crossingham, Tanita Limani, Kate Gowers, Andrew Perugia, James Rusius, Anne-Marie Hacker, Monica L Mullin, Evangelos Katsampouris, Chuen R Khaw, Chuen Khaw, Sheetal Karavadra, Alan Shaw, Chris Valerio, Ali Mohammed, Lynsey Gallagher, Mehran Azimbagirad, Burcu Ozaltin, Maureen Browne, Eleanor Hellier, Catherine Nestor

“…Males (adjusted OR (aOR) 1.16), younger individuals (55–59: aOR 1.70, 60–64: aOR 1.71 and 65–69: aOR 1.78) and those of ethnic minority backgrounds (Asian: aOR 1.31, Black: aOR 1.71 and Mixed: aOR 1.72) were more likely to consent, while individuals from the most deprived socioeconomic quintile were less likely to do so (aOR 0.65).High level of motivation to quit within a defined time frame (aOR 1.92), previous quit attempts in the past 12 months (1–4: aOR 1.65 and ≥5: aOR 1.54) and time to first cigarette of ≤60 min (<5: aOR 2.07, 6–30: aOR 1.55 and 31–60: aOR 1.56) were measures of tobacco dependence associated with a higher likelihood of providing consent.Outcomes were available for 742 referrals. …”
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Designing a comprehensive behaviour change intervention to promote and monitor exclusive use of liquefied petroleum gas stoves for the Household Air Pollution Intervention Network... by J Jaime Miranda, William Checkley, Kyle Steenland, Vanessa Burrowes, Kirk R Smith, Aris Papageorghiou, Abigail Jones, Ghislaine Rosa, Anaité Díaz-Artiga, Gurusamy Thangavel, Kalpana Balakrishnan, Joshua P Rosenthal, Thomas F Clasen, Steven A Harvey, Amit Verma, Kendra N. Williams, Lisa M. Thompson, Zoe Sakas, Mayari Hengstermann, Ashlinn Quinn, Elisa Puzzolo, Jennifer Peel, Vigneswari Aravindalochanan, Dana Boyd Barr, Alejandra Bussalleu, Devan Campbell, Eduardo Canuz, Adly Castañaza, Howard Chang, Yunyun Chen, Marilú Chiang, Maggie L Clark, Rachel Craik, Mary Crocker, Victor Davila-Roman, Lisa de las Fuentes, Oscar De León, Ephrem Dusabimana, Lisa Elon, Juan Gabriel Espinoza, Irma Sayury Pineda Fuentes, Sarada Garg, Dina Goodman, Savannah Gupton, Meghan Hardison, Stella Hartinger, Phabiola M Herrera, Shakir Hossen, Penelope Howards, Lindsay Jaacks, Shirin Jabbarzadeh, Michael A Johnson, Katherine Kearns, Miles Kirby, Jacob Kremer, Margaret A Laws, Pattie Lenzen, Jiawen Liao, Amy E Lovvorn, Fiona Majorin, Eric McCollum, John McCracken, Julia N McPeek, Rachel Meyers, Erick Mollinedo, Lawrence Moulton, Krishnendu Mukhopadhyay, Luke Naeher, Abidan Nambajimana, Durairaj Natesan, Florien Ndagijimana, Azhar Nizam, Jean de Dieu Ntivuguruzwa, Ricardo Piedrahita, Ajay Pillarisetti, Naveen Puttaswamy, Sarah Rajkumar, Usha Ramakrishnan, Rengaraj Ramasami, Davis Reardon, Barry Ryan, Sudhakar Saidam, Sankar Sambandam, Jeremy A Sarnat, Suzanne Simkovich, Sheela S Sinharoy, Damien Swearing, Ashley Toenjes, Lindsay Underhill, Jean Damascene Uwizeyimana, Viviane Valdes, Kayla Valentine, Lance Waller, Megan Warnock, Wenlu Ye, Bonnie Young

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Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y glo... by Mieke Van Hemelrijck, Salvatore Grisanti, Avinash Aujayeb, Martin Forster, Giannis Mountzios, Andrea Napolitano, Bruno Vincenzi, Joachim G J V Aerts, Marina Garassino, Valter Torri, Solange Peters, Alex Friedlaender, Alfredo Addeo, Giuseppe Lo Russo, Roberto Ferrara, Diego Signorelli, Alessandro Russo, So Yeon Kim, Jarushka Naidoo, Scott Gettinger, Heather Wakelee, Martin Sebastian, Mark Awad, Abdul Rafeh Naqash, Alessio Cortellini, Raffaele Giusti, Michele De Tursi, Federica Zoratto, Marco Russano, Rita Chiari, Biagio Ricciuti, Andrea De Giglio, Alain Gelibter, Giuseppe Tonini, Amin H Nassar, Alessandra Curioni-Fontecedro, Eleni Karapanagiotou, Emilio Bria, Jack Bell, Paolo Bironzo, Joao V Alessi, Alessandro Morabito, David J Pinato, Francesco Passiglia, Carlo Genova, Francesca Mazzoni, Alessandro Inno, Francesco Grossi, Luca Cantini, Lorenza Landi, Luigi Della Gravara, Margarita Majem, Uma Mukherjee, Federica Biello, Alessandro Leonetti, Annalisa Guida, Marianna Macerelli, Gabriele Minuti, Giulio Metro, Thomas Newsom-Davis, Eleni Josephides, Andrea Camerini, Elisa Roca, David O’Reilly, Mingjia Li, Laura Mezquita, Teresa Gorría, Claudia A M Fulgenzi, Lauren Young, Joel W Neal, Javier Baena, Francesco Pantano, Jacobo Rogado, Mary Jo Fidler, Teresa Beninato, Federica Pecci, Alessandro Di Federico, Kazuki Takada, Leonardo Brunetti, Talal El Zarif, Laura Moliner, Alberto Servetto, Sukumar Kalvapudi, Sai Yendamuri, Edoardo Garbo, Giuseppina Rita Di Fazio, Monica Loza, Ritujith Jayakrishnan, Michele Montrone, Nichola O Awosika, Bartlomiej Tomasik, Maximilian Rost, Isabelle Monnet, Francesco Agustoni, Artur Katz, Dwight Hall Owen, Michele Ghidini, Armida D’Incecco, Gianpaolo Spinelli, Monica Verrico, Manuel Dupont, Rafael Di Marco Barros, Diego Luigi Cortinovis, Chiara Bennati, Frank Aboubakar Nana, Anne-Marie Dingemans, Taher Abu Hejleh

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The Prognostic Value of Echocardiographic Wall Motion Score Index in ST-Segment Elevation Myocardial Infarction by Michael L. Savage, Karen Hay, Bonita Anderson, Gregory Scalia, Darryl Burstow, Dale Murdoch, Isuru Ranasinghe, Owen Christopher Raffel

“…The prognostic value of WMSI, LVEF, and traditional risk scores (TIMI, GRACE) were compared using multivariable logistic regression modelling. …”
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Serum NT-Pro-BNP versus Noninvasive Bedside Inotropic Index in Paediatric Shock: A Contest of Myocardial Performance in Response to Fluid Loading by Antonius Hocky Pudjiadi, Tuty Rahayu, Stephanie Wijaya, Fatima Safira Alatas

“…Delta NT-pro-BNP in fluid responders (15.00 (−16.00–950.00) ng/mL) did not differ from fluid nonresponders (505.00 (−797.00–1600.00) ng/mL), p=0.456. Postloading SMII >1.25 W·m−2 was associated with fluid responders (AUC: 0.683 (0.553–0.813), p = 0.011), 61.9% sensitivity, and 66.7% specificity, but not preloading SMII. …”
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Factors associated with failure of humerus nonunion surgery in patients with initial nonoperative management by Alexander Hysong, MD, Noah Harrison, MD, Samuel Posey, MD, Ziqing Yu, MS, Andrew T. Chen, MD, Patrick Pallitto, MD, Joseph R. Hsu, MD, William Obremskey, MD, Evidence-Based Musculoskeletal Injury and Trauma Collaborative (EMIT), Hassan Mir, MD, Roman M. Natoli, MD, PhD, Ishani Sharma, MD, MBA, Jenna Jones, Med, Luke A. Lopas, MD, Hassan Farooq, MD, Robert D. Zura, MD, Alexander Padovano, MD, Nathaniel Koutlas, MD, Steve Hemmerly, BS, Elsa Rodriguez, MD, Daniel E. Pereira, MD, Sharon Babcock, MD, Gabriel James Sowards, BS, Martha Holden, AAS, AA, Anna N. Miller, MD, Marc Schatz, MD, Jessica Rivera, MD, PhD, Katrina Bang, MD, Kamryn King, BS, Zachery Hong, BA, Jarrod Dumpe, MD, Gabriella Lea Stribling, BS, Merritt John Thompson, MD, Tracy Johns, MSN, RN-BC, Rachel Seymour, PhD, Susan Odum, PhD, Stephen Sims, MD, Olivia Rice, MD, Ainsley Bloomer, MD, Katheryn Peterson, BSPH, Amber Stanley, BSPH, Mario Cuadra, MD, Gisele Bailey, MS, Matthew Braswell, MD, Landon Bulloch, MD, William Haynes, MD, Josef Jolissaint, MD, Julia Mastracci, MD, Andrew Wohler, MD, Eddie Komie Afetse, BS, BA, Cara Girardi, Juliette Sweeney, BS, Benjamin Averkamp, MD, Meghan Wally, PhD, Madhav Karunakar, MD, Kevin Phelps, MD, Laurence Kempton, MD, Christine Churchill, MA, CCRP, David Macknet, MD, Hannah Pollock, BS, Rodney Arthur, MS, Samuel Cohen-Tanugi, Isaac Boateng, James Michael Ruth, BS, Joseph Michalski, MD, Anna Hemminger, BS, Kathryn Leighty, Mir Ibrahim Sajid, MD, Thea Lance, BA, William Hunter Waddell, MD, Andres Fidel Moreno Diaz, MD, Joseph Gutbrod, BS, Christopher G. Herbosa, BS

“…Level of Evidence:. Therapeutic level III.…”
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Utility of measurement of left ventricular global longitudinal strain by two-dimensional speckle-tracking echocardiography to predict cardiovascular events in patients with left ve... by Susheel Kumar Malani, Digvijay Nalawade, Sridevi Chigulapalli, Shubhangi Kanitkar, Ajitkumar Jadhav, Madhura Gandhi

“…These findings suggest LV GLS and WMSI are valuable indicators for diagnosis and risk assessment, although more extensive studies are needed for validation. …”
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miR-208a-3p discriminates osteoporosis, predicts fracture, and regulates osteoclast activation through targeting STC1 by Hongbing Qian, Fei Jia, Huiling Qin

“…STC1 was identified as a direct target of miR-208a-3p and was negatively regulated by miR-208a-3p. …”
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AVALIA-ULS: perceções dos médicos de família sobre recursos e formação by Juliana Gomes, Ana Águas dos Santos, Maria Inês Sequeira Leal, Filipa Mota Pimenta, Miguel Ornelas Azevedo, José Pedro Antunes, Rui Macedo, Deolinda Chaves Beça, António Luz Pereira

“…RIIS: Revista de Investigação & Inovação em Saúde…”
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Papel do prestador de cuidados: construção de um percurso clínico por enfermeiros especialistas by Renata Lopes dos Santos, Salomé Sobral, Lino André Silva, Énio Bessa, José Filipe Costa, Olinda Pires, Paula Lopes, Nuno Abreu, Eduardo Alves

“…RIIS: Revista de Investigação & Inovação em Saúde…”
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Autocuidado e funcionalidade de pessoas idosas em estruturas residenciais: um estudo transversal by Paulo Azevedo, Ana Costa, Beatriz Correia, Inês Andrade, Jéssica Andrade, Maria Oliveira, Sónia Cunha, Tomás Almeida

“…RIIS: Revista de Investigação & Inovação em Saúde…”
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Uso do trapézio no apoio à mobilidade - Uma perspetiva da enfermagem by Andreia Alves, Carolina Bonito, Inês Costa, Inês João, Pedro Gaspar

“…RIIS: Revista de Investigação & Inovação em Saúde…”
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miR-214-3p Deficiency Enhances Caspase-1-Dependent Pyroptosis of Microglia in White Matter Injury by Liufang He, Tingyan Wei, Yong Huang, Xueli Zhang, Dongbo Zhu, Huazhen Liu, Zhangxing Wang

“…Pharmacology inhibition of caspase-1 cleavage alleviated the pathogenesis of WMI mice. The expression of microRNA miR-214-3p was largely reduced in the microglia of WMI mice compared to controls. …”
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Trauma Surgery and War: A Historical Perspective by Kun Hwang

“…During WWI, Cushing systematized the treatment of head injuries, reducing mortality among head injury patients. …”
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Esophageal Impedance-pH Monitoring and Pharyngeal pH Monitoring in the Diagnosis of Extraesophageal Reflux in Children by Anna Plocek, Beata Gębora-Kowalska, Jakub Białek, Wojciech Fendler, Ewa Toporowska-Kowalska

“…MII-pH and Dx-pH were conducted concurrently in all patients. …”
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Extreme Air Pollution Events Spiking Ionic Levels at Urban and Rural Sites of Indo-Gangetic Plain by Manisha Mishra, U. C. Kulshrestha

“…The WSII concentration spiked during November at both locations (∑WSII = 159.6 and 141.9 µg m−3) due to two extreme air pollution events, viz., i) the burning of crop residue and ii) the Diwali festival. …”
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White Matter Injury in Central Nervous System Disorders by Zheng L, Wang X, Li P, Hao Y, Zhang H, Chen H, Zheng Z

“…However, most previous studies have focused on grey matter injury (GMI), with fewer studies on white matter injury (WMI). …”
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Rescuing the Jews in Lithuania during World War II: Practices of Creating a Lithuanian Museum Narrative by Rūta Šermukšnytė

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心肌灌注分型对冠状动脉慢性完全闭塞病变介入治疗的疗效评估 by 骆炳政, 李明奇, 马墩亮, 吴开泽, 张斌, 费洪文

“…结果相较于灌注异常组，灌注正常组GLS改善幅度更大（<italic>P</italic>=0.028）； PCI术前灌注异常组室壁运动评分（WMSI）相较于灌注正常组更高（<italic>P</italic>=0.002）。在成功PCI术后一年灌注异常组WMSI相比于灌注正常组术后更高（<italic>P</italic>&lt;0.001）。…”
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I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations by Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

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