Screening of SIRT2 inhibitors from natural product databases using computer-aided drug design and molecular dynamics simulation by Tianyi Liu, Hongli Yin, Xue Dong, Qingyang Hu, Xuejiao Hu, Wenxin Yan, Huanhuan Wang, Zhong Li

“…Molecular dynamics simulation reveals that Artonin E and Paleatin B can form stable receptor-ligand complexes in the active pocket of SIRT2 inhibitors. Based on computer-aided drug design and virtual screening and verification techniques, Artonin E and Paleatin B have been identified as inhibitors of SIRT2, which is a key therapeutic target for the treatment of neuroblastoma. …”
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Response to adjunctive antibiotic therapy along with nonsurgical periodontal therapy in the treatment of peri-implantitis and chronic periodontitis patients: An exploratory review by Geetanshu Sethi, Vishakha Grover, Jyoti Gupta, Ashish Jain

“…Materials and Methods: A systematic search of literature on the predefined criteria was conducted using PubMed, Embase, and Scopus. Probing pocket depth, bleeding on probing, clinical attachment level, and microbial load reduction were selected as primary outcomes, whereas plaque index and gingival index were evaluated as secondary outcomes. …”
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The influence of prenatal environmental conditions on the weight of newborn domestic pigs by S. V. Nikitin, S. P. Knyazev, V. I. Ermolayev

“…Using an original algorithm based on the comparison of the coefficients of correlation between the half-nests (the same average genotype and the same conditions of the embryonic environment) and the twin sockets (the same genotype, different conditions of the embryonic environment), it was possible to estimate the relative contribution of the various components to the weight of the newborn in the domestic pigs. …”
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OPERATION «BROTHER’S KEEPER» IN CONTEXT OF THE PALESTINIAN-ISRAELI STANDOFF by V. M. Morozov, A. A. Ermakov

“…The results of the operation «Brother's Keeper» suggested that the radicals of the West Bank may get developed underground infrastructure and developed infrastructure for production of rockets. The events of summer 2014 in zone of the Palestinian- Israeli conflict showed that escalation may spread from one part of the Palestinian land to another.…”
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Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft by Andreas O. Parashis, Charalampos J. Kalaitzakis, Dimitris N. Tatakis, Konstantinos Tosios

“…Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. …”
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Association of Glycated Proteins with Inflammatory Proteins and Periodontal Disease Parameters by Jeneen Panezai, Mohammad Altamash, Per-Erik Engstrӧm, Anders Larsson

“…Fifty-one patients with periodontitis and 20 healthy subjects underwent probing pocket depth (PPD) measurements. PPD total and PPD disease with and without tooth adjustment were used as continuous indices. …”
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Model-Based Leakage Estimation and Remaining Useful Life Prediction of Control Gas Cylinder by Zhenzhen Zhang, Hui Chen, Chao Qi, Yazhou Liu

“…To evaluate the effectiveness of the proposed method, scaling leakage test data, computational fluid dynamics (CFD) simulation results, and liquid rocket engine (LREs) hot test data are used. Calibration results have proved the validity and universality of the method, with the mean absolute error (MAE) for the remaining 80% useful life prediction results being less than 0.02, 0.04, and 1.10. …”
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Synthesis, Biological Activity, and Molecular Modeling Studies of Pyrazole and Triazole Derivatives as Selective COX-2 Inhibitors by Mohyeddin Assali, Murad Abualhasan, Hadeel Sawaftah, Mohammed Hawash, Ahmed Mousa

“…In the diaryltriazole derivatives, compound 15a showed the best inhibitory activity in comparison to all synthesized compounds including the reference celecoxib with IC50 = 0.002 μM and SI = 162.5 as it could better fit the extra hydrophobic pocket which is present in the COX-2 enzyme. Moreover, the docking study supports the obtained SAR data and binding similarities and differences on both isozymes.…”
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FlowMFD: Characterisation and classification of tor traffic using MFD chromatographic features and spatial–temporal modelling by Liukun He, Liangmin Wang, Keyang Cheng, Yifan Xu

“…Expressly, FlowMFD mines the interaction pattern between Tor applications and servers by analysing the time series features (TSFs) of different size packets. Then MFD chromatographic features (MFDCF) are designed to represent the pattern. …”
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Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) by A. Pardo, V. Vanti, F. Lonardi, A. Signoriello, G. Lobbia, G. Lombardo, L. Trevisiol, A. D’Agostino

“…Conclusions Meta-analysis of periodontal parameters (plaque index, gingival index, bleeding index, probing pocket depth, clinical attachment level) revealed an association between orofacial cleft and greater risk for poor oral health and periodontal disease. …”
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Green Synthesis of New Pyrrolo [1,2-a] quinoxalines as Antiproliferative Agents in GPER-expressing Breast Cancer Cells by Gabriele Carullo, Sarah Mazzotta, Francesca Giordano, Francesca Aiello

“…The synthesis of the pyrroloquinoxalinic core was employed following the Pictet–Spengler reaction, using the surfactant p-dodecylbenzene sulphonic acid (p-DBSA), as catalyst. …”
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Effects of the Air Inlet Angle on the Combustion and Ablation Environment of a Hybrid Powder-Solid Ramjet by Jinjin Wang, Yihao Wen, Bailin Zha, Zhigao Xu, Tianhao Zhang

“…A hybrid powder-solid ramjet (HPSR) that combined the advantages of a solid rocket ramjet (SRJ) and a powder ramjet engine was investigated in this research. …”
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Rheokinetic Analysis of Hydroxy Terminated Polybutadiene Based Solid Propellant Slurry by Abhay K Mahanta, Monika Goyal, Devendra D Pathak

“…This opens up an avenue for a “freeze-and-store”, then “warm-up and cast”, mode of manufacturing of very large solid rocket propellant grains.…”
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Intrastromal autologous implantation of adipose derived adult stem cells for the management of established corneal scars by Jorge L. Alio del Barrio, Alberto Parafita-Fernandez, Daniel Gomez Plaza, Maria Eugenia Fernandez, Jorge L. Alio

“…Observations: ADASC were isolated by elective liposuction, and a solution composed of 3x106 ADASC contained in 1mL saline was used to soak a corneal intrastromal pocket created with femtosecond laser at mid-depth. …”
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Investigation on Acoustic Properties of Thruster Chamber with Coaxial Injectors and Plenum Chamber by Dekun Gao, Jianxiu Qin, Huiqiang Zhang

“…Based on the URANS equation, a numerical simulation is carried out for acoustic properties of the thruster chamber with coaxial injectors and plenum chamber in a liquid rocket engine. Pressure oscillations with multiacoustic modes are successfully excited in the chamber by using the constant volume bomb method. …”
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İÇ DENETİM PERSPEKTİFİNDEN KURUMSAL KÜLTÜR DENETİMİ: UYGULAMA MODEL ÖNERİSİ by Hayrettin Usul, Elif Çağlan

“…Geçtiğimiz yüzyılın sonlarından itibaren dünya çapında yaşanan şirket yolsuzlukları ve skandallar geleneksel iç denetim faaliyetlerinin etkinliğinin sorgulanmasına yol açmıştır. …”
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Study on the Large Deformation Characteristics and Disaster Mechanism of a Thin-Layer Soft-Rock Tunnel by Xiulian Zhang, Manchao He, Fengnian Wang, Gan Li, Shengxin Xu, Zhigang Tao

“…Furthermore, after the surrounding rock was softened by water absorption, the floor of the tunnel, the left shoulder socket, and the right side of the tunnel are deformed greatly. …”
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Effects of Igneous Intrusion on Microporosity and Gas Adsorption Capacity of Coals in the Haizi Mine, China by Jingyu Jiang, Yuanping Cheng

“…The trap effect of the sill prevented the high-pressure gas from being released, forming gas pocket. Mining activities near the sill created a low pressure zone leading to the rapid accumulation of methane and gas outbursts in the Haizi Mine.…”
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Fault Prediction and Recovery Using Machine Learning Techniques and the HTM Algorithm in Vehicular Network Environment by Salah Zidi, Bechir Alaya, Tarek Moulahi, Amal Al-Shargabi, Salim El Khediri

“…Our contribution also relates to a study of the attributes of interest for the algorithm used during the detection phase, namely the hierarchical temporal memory algorithm (HTM). The packets exchanged by the vehicle are grouped in instant description windows. …”
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Grain refinement and improved mechanical properties of as-cast Mg-3Gd alloy by Zr addition by Mohammadreza Maghzi, Hamed Mirzadeh, Reza Mahmudi

“…Shear punch testing (SPT) and hardness measurements revealed substantial improvements in shear yield stress (SYS), ultimate shear strength (USS), and Vickers hardness (HV) with increasing Zr content. …”
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