Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

Get full text

Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma by Wanchen Cao, Kai Gao, Yi Zhao

“…Pseudotime analysis demonstrated that these three cell types underwent three distinct differentiation stages, during which the expression levels of the biomarkers ENTPD1, SERPINA1, and TACSTD2 showed stage-specific trends.ConclusionIn summary, this study combines RNA-seq and scRNA-seq analysis techniques to identify ENTPD1, SERPINA1, and TACSTD2 as potential biomarkers for PTC at the transcriptomic level and tissue stem cells, epithelial cells, and smooth muscle cells as key cells in PTC at the cellular level. …”
Get full text

Transcriptome analysis of historic olives reveals stress-specific biomarkers by Hamad A. Alkhatatbeh, Monther T. Sadder, Nizar Haddad, Nizar Haddad, Ibrahim Al-Amad, Mohammad Brake, Nawal A. Alsakarneh, Abdulsalam M. Alnajjar

Get full text

Comparative Transcriptome Analysis of Susceptible and Resistant Rutaceae Plants to Huanglongbing by Huihong Liao, Fuping Liu, Xi Wang, Hongming Huang, Qichun Huang, Nina Wang, Chizhang Wei

“…The transcriptome data showed that in the susceptible Ponkan Mandarin, there were 1519 upregulated genes and 700 downregulated genes, while in the resistant Punctate Wampee variety, there were 1611 upregulated genes and 1727 downregulated genes. …”
Get full text

Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis by Xinyi Lyu, Jiahao Shi, Qi Liu, Mingjun Jiang, Xilian Liu, Yulan Li, Shuqin Ding, Xianpeng Dai

“…The proliferation analysis showed that the portion of EDU+ or Ki-67+cells consisted of granulocytes and macrophages, and after EPO treatment, only macrophages showed a significant increase in their number and proportion, while granulocytes did not show a significant response to EPO stimulation.ConclusionLong term high-dose EPO treatment may lead to splenomegaly and immunosuppression of the local immune microenvironment in mice. …”
Get full text

Transcriptome analysis reveals regulatory mechanism of postharvest softening in kiwiberry by Zhao Liu, Yang Sun, Zhenpan Liu, Jianyu Song, Weicong Yang, Zhannan Wang, Taiming Liang, Dejun Liang

“…Results Morphological observations and analysis of physical parameters showed that the skin of kiwiberry did not change markedly from the 1st to the 7th day after harvest, while the colour of the inner pericarp gradually turned yellow. …”
Get full text

Systematic analysis and exploration of single-cell transcriptomes in aortic aneurysm by ZHANG Xingyu, LI Ruogu

“…Cellular senescence was scored and compared based on the SenMayo Senescence gene set using the AUCell package.Single-cell transcriptional data were simulated as traditional transcriptome data for differential gene screening and gene pathway enrichment analysis of pericytes.Results·A total of nine datasets meeting the criteria were included. …”
Get full text

Effects of different temperatures on chondrocyte growth: a transcriptomic analysis by Wei Zhao, Yingsong Wang, Jingming Xie, Jin Zhou, Zhi Zhao, Tao Li, Zhiyue Shi, Jie Xiao

Get full text

Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis by Changyuan Huang, Bin Zeng, Bo Zhou, Guanming Chen, Qi Zhang, Wenhong Hou, Guozhi Xiao, Li Duan, Ni Hong, Wenfei Jin

Get full text

Interaction between the liver transcriptome and gut microbiota in mice during Toxoplasma gondii infection as identified by integrated transcriptomic and microbiome analysis by Yang Zou, He Ma, Xing Yang, Xin-Yu Wei, Chao Chen, Jing Jiang, Tao Jiang

“…Liver transcriptome analysis identified numerous differentially expressed (DE) non-coding RNAs and mRNAs potentially potentially involved in mediating liver immune responses and inflammation induced by T. gondii. …”
Get full text

Comparative Analysis of Floral Transcriptomes in <i>Gossypium hirsutum</i> (Malvaceae) by Alexander Nobles, Jonathan F. Wendel, Mi-Jeong Yoo

“…Functional enrichment analysis highlighted organ-specific roles: genes upregulated in bracts were enriched for photosynthesis-related GO terms, while diverse functions were enriched in floral organs, supporting their respective functions. …”
Get full text

Transcriptome analysis of Ipomoea cairica algicidal mechanism against Phaeocystis globosa by Dayong Liang, Huanxin Li, Yuxuan Pan, Zihan Liu, Hua Xiang

Get full text

Transcriptomic and functional analysis of triphenyl phosphate exposure in prostate cancer progression by Li Cai, Guizhi Du

“…Results Exposure to 0.1 µM TPP significantly enhanced prostate cancer cell proliferation and invasion. Transcriptomic analysis revealed 521 upregulated and 964 downregulated genes post-treatment. …”
Get full text

Physiological and transcriptomic analysis of Spartina alterniflora in response to imazapyr acid stress by Yaning Liu, Zhengmao Li, Lixia Li, Xiangyang Jiang, Chen Gao, Jiqiang Zhao

“…Meanwhile, total root length, root surface area and biomass of S. alterniflora were suppressed after imazapyr acid exposure. In transcriptomic analysis, imazapyr acid inhibited the expression of genes involved in phenylpropanoid biosynthesis, nucleotide sugar-related metabolism, valine, leucine and isoleucine biosynthesis, and DNA replication in S. alterniflora. …”
Get full text

Integrated analysis of intestinal microbial community and muscle transcriptome profile in rabbits by Shengbo Meng, Shanshan Xing, Huifen Xu, Jing Li, Yixuan Jiang, Hui He, Hanfang Cai, Ming Li

“…In order to better understand the relationship between gut microbiota and gene expression in skeletal muscle of rabbits, caecum contents and longissimus dorsi tissues of rabbits at 0 d (S1), 35 d (S2) and 70d (S3) were collected and subjected for 16S rRNA sequencing and transcriptome sequencing. Our results showed that, among three groups of rabbits, Firmicutes and Bacteroidetes were the dominant phyla at the phylum level, while Akmansia, Bacteroides and Ruminobacter were the dominant genera at the genus level, and the relative abundance of Akmansia and Bacteroides increased firstly and then decreased from 0 d to 70 d. …”
Get full text

Transcriptomic analysis of the symbiotic responsivity trait in pea (Pisum sativum L.) by D. O. Kuzmina, E. A. Zorin, A. S. Sulima, D. A. Romanyuk, M. L. Gordon, A. I. Zhernako, O. A. Kulaeva, G. A. Akhtemova, O. . Shtark, I. A. Tikhonovich, V. A. Zhukov

“…In order to get insight into the molecular genetic mechanisms underlying the symbiotic responsivity, a transcriptomic analysis of whole root systems of pea plants of the ‘responsive’ genotype k-8274 (cv. …”
Get full text

Transcriptome analysis of sugar beet in response to the pathogenic oomycete Aphanomyces cochlioides by Valentina Rossi, Louise Holmquist, Erik Alexandersson, Laura Grenville-Briggs

“…With the aim to identify key genes involved in plant defense responses against the root rot, we performed a transcriptome analysis of sugar beet interactions with A. cochlioides. …”
Get full text

Physiological and Transcriptomic Analysis of a Sepal Mutant in <i>Phalaenopsis</i> by Yu Qi, Yenan Wang, Fei Dong, Jiao Zhu, Xiaohui Lv

“…Nine glycosylated anthocyanins were identified and their contents were significantly upregulated in the Se-red of mutant flowers. Transcriptomic analysis identified 9408 differentially expressed genes, including 4934 upregulated and 4474 downregulated genes. …”
Get full text

Identification of predictors for bacterial meningitis diagnosis based on transcriptomics and genetic analysis by Hexiang Jiang, Xibing Yu, Jingyan Fan, Houhui Song, Yang Yang

Get full text

Integrated transcriptomic analysis reveals evolutionary and developmental characteristics of tendon ossification in teleost by Xu-Dong Wang, Fei-Long Shi, Jia-Jia Zhou, Zheng-Yu Xiao, Tan Tu, Xue-Mei Xiong, Chun-Hong Nie, Shi-Ming Wan, Ze-Xia Gao

Get full text