Genomic Features of <i>Taiwanofungus gaoligongensis</i> and the Transcriptional Regulation of Secondary Metabolite Biosynthesis by Yadong Zhang, Yi Wang, Xiaolong Yuan, Hongling Zhang, Yuan Zheng

“…Additionally, <i>T. gaoligongensis</i> exhibits a high degree of similarity to <i>Laetiporus sulphureus</i>, despite belonging to a different genus within the same family. Transcriptome analysis reveals significant variation in the expression levels of PKS and TPS genes across different cultivation conditions. …”
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Effects of combined hypoxia and irradiation on mouse bone marrow hematopoietic cells by YANG Xinhai, CHEN Fang, QUAN Yong

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The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility in Oryza sativa L by Yusheng Xu, Yusheng Xu, Dingyang Yuan, Meijuan Duan

“…This article aims to utilize dominant nuclear male sterile lines, which were created through the ectopic expression of ZmMs7 in the genetic background of rice, for the purpose of heterosis utilization.MethodsAt the same time, we conducted a study on the spatiotemporal expression characteristics of ZmMs7, performed transcriptome analysis, and implemented yeast two-hybrid experiments to elucidate its molecular regulatory mechanisms in mediating dominant nuclear male sterility in rice.ResultsThe results confirm the successful construction of a dominant nuclear male-sterile (NMS) vector system (p5126-ZmMs7-DsRed) using the exogenous male-sterile gene ZmMs7. …”
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Adaptation to Nighttime Light via Gene Expression Regulation in Drosophila suzukii by Natsumi Takenaka, Yuma Takahashi

“…The circadian rhythm length was disrupted in rural populations but not in urban populations. Transcriptomic analysis revealed ALAN‐induced gene expression changes, particularly in urban females, with photoreceptor‐ and circadian rhythm‐related genes responding differently between urban and rural populations. …”
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CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses by Lei Wang, Lu Lu, Xia Guo, Feng Shao, Hai-Jun Ma, Yun Zhou

“…Key regulatory genes were identified through transcriptomic analysis, weighted gene co-expression network analysis (WGCNA), and machine learning approaches. …”
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Effects of dietary protein levels on genes related to subcutaneous fat deposition and lipid metabolism in Tibetan sheep by Xianhua Zhang, Zhenling Wu, Jiacheng Gan, Rengeerli Sa, Wei Gao, Yu Zhang, Shengzhen Hou, Linsheng Gui

“…The LP group had significantly lower C22:0 and higher C20:2, C20:3n6, C20:4n6, and C20:3n3 levels than the HP group (P < 0.05). Transcriptomic analysis revealed 70 DEGs, of which 33 were upregulated and 37 were downregulated. …”
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Impact of Arsenic Stress on the Antioxidant System and Photosystem of <i>Arthrospira platensis</i> by Jiawei Liu, Jie Du, Di Wu, Xiang Ji, Xiujuan Zhao

“…The algae mitigated arsenic-induced oxidative stress by increasing cellular metabolic rates, enhancing cell wall stability, and reducing membrane lipid peroxidation. Transcriptome analysis revealed that pathways related to oxidative phosphorylation and chlorophyll degradation were upregulated under arsenic stress, while the expression of membrane transporters was significantly downregulated. …”
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Immunization induces inflammation in the mouse heart during spaceflight by Alicia L. Veliz, Lorelei Hughes, Delia Carrillo, Michael J. Pecaut, Mary Kearns-Jonker

“…Analysis of the mouse heart transcriptome was performed on flight control and flight-immunized mice. …”
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Matrine Attenuates <i>Streptococcus agalactiae</i> Virulence by Suppressing Capsular Polysaccharide Synthesis and Host Adhesion Pathways by Shijiao Guo, Kaiming Wang, Hua Zhang, Chaochao Luo, Zixuan Zhao, Jinjin Tong

“…The aim of this study was to investigate the regulatory effects of matrine on the virulence of the ATCC strain (ATCC13813) and clinical GBS strains by transcriptome analysis and qRT-PCR validation. The results showed that the ABC transporter, peptidoglycan biosynthesis, and quorum-sensing pathways were significantly altered in ATCC (4 mg/mL) and GBS (12 mg/mL) strains after matrine treatment at MIC concentrations. …”
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Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery. by Sharada Mokkapati, Ganiraju Manyam, Alexis R. Steinmetz, Côme Tholomier, Alberto Martini, Woonyoung Choi, Bogdon Czerniak, Byron H Lee, Colin P Dinney, David J McConkey

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Metabolic, transcriptional, and hormonal responses of Panax ginseng C. A. Meyer to nitrogen deficiency by Hao Liang, Hai Sun, Cai Shao, Bochen Lv, Jiapeng Zhu, Weiyu Cao, Jixin Zhou, Yayu Zhang

“…However, an integrated analysis of the metabolome, transcriptome, and hormone profiles associated with N deficiency in Panax ginseng has not been previously conducted. …”
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A CC‐NB‐ARC‐LRR Gene Regulates Bract Morphology in Cotton by Sunyi Yan, Zhanfeng Si, Guoan Qi, Yihao Zang, Lisha Xuan, Lu He, Yiwen Cao, Xiaoran Li, Tianzhen Zhang, Yan Hu

“…They serve multiple functions such as attracting pollinators, aiding tolerance of abiotic stressors, and conducting photosynthesis. While previous studies extensively examine bract function, the molecular mechanisms underlying bract growth remain unknown. …”
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Effects of β-1,3-glucan feed supplementation on the growth, liver biochemistry, transcript levels and intestinal microorganisms of swamp eel (Monopterus albus) by Mengyu Bao, Wenzong Zhou, Tian Zhu, Weiwei Huang, Quan Yuan, Hang Yang, Yuning Zhang, Weiwei Lv, Qichen Jiang

“…Monopterus albus were reared for 56 days, the final body weight, weight gain rate, survival rate, and specific growth rate were significantly increased, while the feed conversion rate was reduced considerably, in EG-2, EG-3, and EG-4 compared with the CT (P < 0.05). …”
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Global changes in gene expression of mRNA and miRNA in liver tissues of Micropterus salmoides after infection with Aeromonas hydrophila by Zhi Lei Yao, Ming Yu, Xiao Wang, Hong Ju Chen, Xiang Shan Ji, Yan Zhao

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An enhanced gene function analysis platform for Gastrodia Elata integrating further omics data and analysis tools by Bingbing Pan, Jingjie Zhang, Jiangxin Yang, Hang Yang, Qi Pan, Panpan Zhu, Jun Li, Jiaotong Yang

“…The growing multi-omics data demands an updated platform to include the latest G.elata genome and transcriptome, thereby enhancing gene function analysis for researchers. …”
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Physiological measurement and screening of key genes of the rhizome cold tolerance in the herbaceous peony cultivated over winter in Harbin(哈尔滨越冬栽培的芍药根茎耐寒生理测定和关键基因筛选)... by 王琪瑶(WANG Qiyao), 李丹青(LI Danqing), 郭俊宏(GUO Junhong), 陈晓璇(CHEN Xiaoxuan), 陈炀(CHEN Yang), 夏宜平(XIA Yiping), 张佳平(ZHANG Jiaping), 刘志洋(LIU Zhiyang)

“…We investigated the physiological and molecular responses of their rhizomes to cold stress under freezing conditions through physiological observations, transcriptome sequencing, and gene expression analysis. …”
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Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension by Claudia Desireé Norzagaray-Valenzuela, Claudia Desireé Norzagaray-Valenzuela, Marco Antonio Valdez-Flores, Josue Camberos-Barraza, Josue Camberos-Barraza, Alberto Kousuke De la Herrán-Arita, Juan Fidel Osuna-Ramos, Javier Magaña-Gómez, Carla Angulo-Rojo, Alma Marlene Guadrón-Llanos, Katia Aviña-Padilla, Loranda Calderón-Zamora

“…This study aimed to uncover shared transcriptional programs and disease-specific regulatory networks contributing to cardiometabolic dysfunction.MethodsWe systematically selected transcriptomic datasets and employed an integrative systems biology approach that combined differential gene expression analysis, co-expression network construction, protein-protein interaction mapping, transcription factor activity inference, and network rewiring analysis. …”
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The impact of Sarcocystis infection on lamb flavor metabolites and its underlying molecular mechanisms by Kang Zhang, Huan Teng, Huan Teng, Li Zhu, Bin Ni, Lai Jiewei, Li Shanshan, Zhao Yunong, Xiao Guo, DanQu Lamu

“…Transcriptomic analysis identified 574 DEGs, including upregulated genes such as MAPK12, COX6A2, and RXRA, which are involved in lipid metabolism, fatty acid oxidation, and thermogenesis, and downregulated genes such as COX2, COX3, and ADIPOQ, which are associated with mitochondrial function and energy metabolism. …”
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The Response Characteristics of One <i>Saccharomyces cerevisiae</i> Strain Under Continuous Passage in Artificial Culture Medium by Tengyu Ma, Hongguang Zhu, Jiajia Yin, Yu Tian, Wenjing Yan, Haixin Sun

“…It thrived in a pH range of 4–5.5 and efficiently utilized various carbon and nitrogen sources; (2) After serial subculturing, the strain’s ethanol production capacity and fermentation rate partially declined and then stabilized, while maintaining strong tolerance to high ethanol concentrations and hyperosmotic stress; (3) Transcriptomic analysis revealed significant differential expression of genes related to lipid metabolism, amino acid metabolism, and other pathways under high-glucose stress following continuous subculturing. …”
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Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility by Jing Yang, Lingtao Yang, Ying Zhou, Fengyang Cao, Hongkun Fang, Huan Ma, Jun Ren, Chunyu Huang, Lianghui Diao, Qiyuan Li, Qionghua Chen

“…Methods We conducted a comprehensive computational analysis integrating publicly available endometrial transcriptomic datasets with prospectively collected samples. …”
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