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521
Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance
Published 2025-03-01“…Here, we curated mouse transcriptomic data from mature sperm and selected the most abundant mRNAs (above the 0.7 quantile). …”
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522
Integrative Analysis of Transcriptomic and Metabolomic Profiles Identifies Distinct Dynamic Changes in Primary and Secondary Metabolites in Grape Berries Under Fruit-Specific Light...
Published 2025-04-01“…Light influences fruit development and quality through two primary pathways: its effect on vegetative organs, which subsequently impacts the fruit, and its direct effect on the fruit itself. While the mechanism of the former pathway is well-documented, the direct impact of light on fruit has been less studied due to limitations in applying controlled light exposure to preharvest fruit. …”
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523
Semen Quality, Testicular Cell Apoptosis, and Transcriptome Analysis Following Mild Scrotal Heat Stress in Wugu–Hu Crossbred and Hu Rams
Published 2025-03-01“…Wugu–Hu rams demonstrate more transcriptomic changes. Further GO analysis revealed enrichment in spermatogenesis-related processes, while KEGG analysis identified Oocyte meiosis and cell cycle pathways, with a downregulation of key genes (CDK1, CDK2, CDC20, and PLK1) indicating impaired meiosis in Wugu–Hu rams. …”
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524
The pseudo-type response regulator gene Clsc regulates rind stripe coloration in watermelon
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525
Expression of ABC transporters negatively correlates with ectoine biosynthesis in Halomonas campaniensis under NaCl and ultraviolet mutagenesis treatments revealed by transcriptomi...
Published 2024-11-01“…NaCl induction resulted in a 20-fold increase, while UV treatment led to at least 2.5-fold increases in ectoine production. …”
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526
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527
Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network
Published 2025-06-01“…Biofuel production through microbial fermentation offers a green, sustainable, and renewable alternative to chemical synthesis. While enhanced production of isopentanol has been achieved in a variety of chassis, the fermentation yield has not yet reached levels suitable for industrial-scale production. …”
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528
Metabolome integrated with transcriptome, and genome analysis revealed higher accumulations of phytoalexins enhance resistance against Magnaporthe oryzae in new Zhefang rice variet...
Published 2025-07-01“…Notably, 55% of these metabolites exhibited similar expression patterns across both lines, while 9 DAMs displayed contrasting patterns at 48 h in response to pathogen infection. …”
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529
Physiological and Transcriptome Analysis Reveal the Underlying Mechanism of Salicylic Acid-Alleviated Drought Stress in Kenaf (<i>Hibiscus cannabinus</i> L.)
Published 2025-02-01“…In this study, the kenaf seedlings were subjected to physiological and transcriptomic analysis under control (CK), moderate drought stress (D), and moderate drought stress with 1 mM SA (D_SA). …”
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530
Long-term thermal acclimation enhances heat resistance of Hong Kong catfish (Clarias fuscus) by modulating gill tissue structure, antioxidant capacity and immune metabolic pathways
Published 2024-10-01“…Transcriptome analysis identified 520 and 463 differentially expressed genes in the NT and HT groups, respectively, in response to acute temperature changes. …”
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531
Transcriptome and targeted metabolome analysis of lipid profiles, nutrients compositions and volatile compounds in longissimus dorsi of different pig breeds
Published 2025-05-01“…Also, the contents of medium-long chain fatty acids and γ-aminobutyric acid (GABA) were higher, while Asp was lower in LD of SW pigs compared with LW pigs (p<0.05). …”
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532
Dexamethasone’s Clinical Efficacy in Experimental Autoimmune Pancreatitis Correlates with a Unique Transcriptomic Signature, Whilst Kinase Inhibitors Are Not Effective
Published 2024-10-01“…In the principal component analysis of pancreatic transcriptomics, poly I:C-injected mice treated with tofacitinib, takinib, or solvent clustered together, while untreated and dexamethasone-treated mice formed separate, unique clusters. (4) Conclusions: Dexamethasone effectively reduced AIP severity, while takinib and tofacitinib were ineffective. …”
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533
Transcriptomic Profiling Reveals Differences in Slow‐Twitch and Fast‐Twitch Muscles of a Cigarette Smoke‐Exposed Rat Model
Published 2025-02-01“…This study aimed to elucidate the histomorphological, biochemical and transcriptomic changes induced by CS on both slow‐twitch and fast‐twitch muscles. …”
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534
Microbial community structure in lake and wetland sediments from a high Arctic polar desert revealed by targeted transcriptomics.
Published 2014-01-01“…While microbial communities play a key role in the geochemical cycling of nutrients and contaminants in anaerobic freshwater sediments, their structure and activity in polar desert ecosystems are still poorly understood, both across heterogeneous freshwater environments such as lakes and wetlands, and across sediment depths. …”
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535
Transcriptome Profiling Reveals Genetic Basis of Muscle Development and Meat Quality Traits in Chinese Congjiang Xiang and Landrace Pigs
Published 2025-06-01“…GO and KEGG pathway analyses revealed that up-regulated genes in CX pigs were significantly enriched in immune response pathways (adjusted <i>p</i>-value < 0.01), while down-regulated genes were primarily associated with myosin complex formation and <i>PPAR</i> signaling pathway. …”
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536
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer’s disease
Published 2025-05-01“…Of its three isoforms, APOE2 is thought to be protective, while APOE4 increases AD risk. We hypothesised that the isoforms change gene regulatory patterns that link back to biological function by shaping microglial transcriptomic and chromatin landscapes. …”
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537
Hepatic transcriptome profiling unveils candidate genes in cattle with liver abscesses under the influence of beef genetics in dairy cattle.
Published 2025-01-01“…Notably, the most highly up-regulated genes were FGF23, NXPH4, and CYP7A1, while EPHA6, CD70, and INHBA showed the most significant downregulation. …”
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538
Differential responses of the intestine and liver transcriptome to high levels of plant proteins in diets for large yellow croaker (Larimichthys crocea)
Published 2025-03-01“…Current fish meal - based feeds face issues like high cost and resource depletion, while plant protein sources have potential but also controversies. …”
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539
The Potential Role of GJA1 and SPP1 Expressed by the Endometrium Based on Single Cell Transcriptome Analysis in Endometrial Infertility
Published 2024-01-01“…Background: Endometrial infertility accounts for a significant proportion of infertility cases, and single-cell transcriptome data have revealed that hub genes may play an important role during pregnancy. …”
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540