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381
Transcriptomic Analysis of Gibberellin-Mediated Flower Opening Process in Tree Peony (<i>Paeonia suffruticosa</i>)
Published 2025-03-01“…In contrast, all flower buds treated with 1000 mg/L GA<sub>3</sub> aborted, while only one flower bud in the control group bloomed after 56 days. …”
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382
Integrating transcriptomic and metabolomic analyses to characterize the potential function of SLC1A5 in thyroid cancer
Published 2025-05-01“…SLC1A5 expression in TPC-1 and B-CPAP was knocked down using SLC1A5 siRNA to investigate its effects on cell growth and apoptosis. Transcriptome sequencing and metabolite analysis were carried out in the SLC1A5 siRNA group to identify major transcriptomic or metabolite changes that could lead to apoptosis. …”
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383
Combined Physiology and Transcriptome Analyses Provide Insights into Malformed Fruit of <i>Cocos nucifera</i> L.
Published 2025-03-01“…Transcriptomic dissection revealed 6370 functionally annotated differentially expressed genes (DEGs), comprising 4235 upregulated and 2135 downregulated transcripts. …”
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384
A global overview of transcriptome dynamics during the late stage of flower bud development in Camellia oleifera
Published 2025-02-01“…The study investigated the dynamic changes and regulatory patterns of different tissues within flower buds from flower bud development to flowering, employing a multi-faceted approach that included cellular dissection, analysis of hormone content, and transcriptome analysis. This study demonstrates that ABA and SA, rather than GA3, IAA, ZT, acts as potentially effective endogenous agents to promote flowering in the later stages of flower development, which is a critical period for the maturation of pollen and embryo sacs; while ZT plays a more significant role in the early stages of flower bud development. …”
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385
Integrated analysis of methylomic and transcriptomic profiles in fetal mouse hypothalamus in response to maternal gestational exposure to arsenic
Published 2025-07-01“…Integrated analysis revealed that genes with hypermethylated promoters tended to be downregulated, while those with hypomethylated promoters were often upregulated, supporting a regulatory association between DNA methylation and gene expression. …”
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386
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387
Transcriptomic Analysis for Key Periods of Radicle Development in Contrasting Soybean Varieties HN75 and HN76
Published 2025-05-01“…These findings unravel mechanisms governing leguminous radicle development while establishing molecular blueprints for engineering cultivation protocols that would enhance soybean sustainability in edaphically constrained environments.…”
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388
Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues
Published 2025-05-01“…Herein, we delineate the transcriptomic diversity of human iNKT cells from multiple immunologically relevant hematologic tissues. …”
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389
Integration of multi-omics transcriptome-wide analysis for the identification of novel therapeutic drug targets in diabetic retinopathy
Published 2024-12-01“…HLA-DQ family genes have a frequent occurrence, while RPS26, WFS1 and SRPK1 were validated as the genetic network’s linchpins. …”
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390
Integrated transcriptome and metabolome analysis of photoperiod effects on testosterone secretion in ChaHua chicken No.2 Roosters
Published 2025-04-01“…This study investigated the impact of light duration on Testosterone secretion in Chahua No.2 roosters, utilizing combined Transcriptome and Metabolome analyses to uncover critical genes, Metabolites, and signaling pathways. …”
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391
Identification of hub genes regulating seed germination viability in soybean via comparative transcriptome analysis and WGCNA
Published 2025-07-01“…Seed germination viability is a crucial foundation for soybean storage life and seedling establishment, while its regulatory factors remains largely unexplored. …”
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392
Construction of dynamic ceRNA regulatory networks in osteogenesis during fracture healing based on transcriptomic analysis
Published 2025-07-01“…GO and KEGG enrichment analyses were performed to explore potential biological mechanisms. miRNA-mRNA interactions were predicted using TargetScan, miRWalk, and miRDB, while RNA22 v2 was used for lncRNA-miRNA interactions. …”
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393
A comprehensive transcriptome based meta-analysis to unveil the aggression nexus of oral squamous cell carcinoma
Published 2025-06-01“…To address this, an integrative meta-analysis of six publicly available transcriptomic profiles, categorized by lymph nodal status, is conducted. …”
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394
Integration of metabolic and transcriptomic analyses for revealing the galactose metabolism of tobacco (Nicotiana tabacum) under salt stress
Published 2025-06-01“…Chlorophyll synthesis was impacted by decreased 5-aminolevulinic acid production, while proline accumulation helped mitigate cell damage. …”
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395
Transcriptomic, phenotypic and physiological analyses identify candidate regulators of Dendrobium stigma maturation and pollen-stigma interaction
Published 2025-08-01“…O-GlcNAc glycosylation was detected in the stigma transcriptome for the first time, potentially linked to kinase activity and immune responses. …”
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396
A Transcriptomics Approach to Unveil the Antioxidant Effects of Tryptophan on Oocyte Quality Under Oxidative Stress in Pigs
Published 2025-06-01“…The results demonstrated that tryptophan supplementation significantly reduced oxidative stress markers such as H<sub>2</sub>O<sub>2</sub> and malonaldehyde (MDA) while restoring key antioxidant enzymes such as superoxide dismutase (SOD), and catalase (CAT) confirming its antioxidant role. …”
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397
Integrated metabolome and transcriptome analysis reveals key genes and pathways associated with egg yolk percentage in chicken
Published 2025-03-01“…To elucidate the underlying mechanisms that contribute to variations in egg yolk percentage, we performed integrated transcriptome and metabolome analyses on the liver, ovary, and magnum tissues of Rhode Island Red chickens with high and low yolk percentages. …”
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398
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399
The effects and mechanisms of Xiaoyao San on nonalcoholic fatty liver disease rat based on transcriptomics and proteomics analysis
Published 2025-03-01“…Specifically, XYS down-regulated the expressions of NF-κB, p-NF-κB, FOXO1, TGF-β1, RIP3, and p-MLKL, while up-regulating cAMP, PKA, p-PKA, and PPARα. …”
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400