Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress by Bingxing An, Peihao Liu, Zhirui Yang, Fan Ying, Dawei Liu, Jie Wen, Guiping Zhao

“…The hypothalamus DEGs enriched in neurotransmitter biosynthesis and Notch signaling pathways, while the pituitary DEGs exhibited changes in calcium and insulin signaling pathways. …”
Get full text

Novel insights into the genetic basis and transcriptomic elucidation of virulence attenuation in Pseudomonas syringae pv. actinidiae variants by Muhammad Asif, Renjian Hu, Ting Xie, Rong Fan, Youhua Long, Yong Wang, Shiping Wu, Zhibo Zhao, Lili Huang

“…Genomic sequencing revealed that the T3SS of G126 was defective due to a single-nucleotide polymorphism in the hrpR gene, while G282 was entirely deficient in the type VI secretion system (T6SS), which potentially regulates the expression of T3SS genes. …”
Get full text

Transcriptome and hormones metabolome joint analyses reveal the key molecular mechanism of Sweetpotato storage roots sprouting by Fan Ding, Xue Zou, Heling Fan, Li-ping Rao, Jian Sun, Qiang Li

“…Hormone metabolites detection results showed that low abscisic acid (ABA) concentrations are crucial for SPSRS, while high indole-3-acetic acid (IAA) concentrations play a promoting role. …”
Get full text

Multi-transcriptomics predicts clinical outcome in systemically untreated breast cancer patients with extensive follow-up by Thi T. N. Do, Ines Block, Mark Burton, Kristina P. Sørensen, Martin J. Larsen, Anne Marie Bak Jylling, Bent Ejlertsen, Anne-Vibeke Lænkholm, Qihua Tan, Torben A. Kruse, Mads Thomassen

“…The specificity level for the multi-transcriptomic dataset was 85% after voting while it was 38%, 48% and 82% for mRNAs, lncRNAs and miRNAs, respectively. …”
Get full text

Comparative transcriptome analysis reveal gene regulation of dormancy release in Cardiocrinum giganteum seeds induced by temperature by Yefang Li, Xuejiao Li, Fengrong Li, Lele Wang, Hongling Li, Yan Zhao, Wenling Guan

“…In this research, transcriptome profiles at different germination stages of seeds subjected to variable temperature stratification were systematically analyzed and compared, while the embryo length of corresponding seed samples was quantitatively measured. …”
Get full text

Immuno-oncologic profiling by stage-dependent transcriptome and proteome analyses of spontaneously regressing canine cutaneous histiocytoma by Alina K. Loriani Fard, Alexander Haake, Vladimir Jovanovic, Sandro Andreotti, Michael Hummel, Benjamin-Florian Hempel, Achim D. Gruber

“…A stage-specific increase of CD80 expressing cells was recorded in CCH from the tumor bottom to the top, while CD86 was continuously and homogenously expressed at high levels. …”
Get full text

Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis by Dayan Hu, Jieliang Jian, Jinpeng Zhang, Xiaojun Xu, Shu Wang, Cuiping Gong, Yuanqin Zhang, Pengcan Zhu, Zhimin Gu, Wenzhi Guan

“…RT-qPCR validates the reliability of transcriptome sequencing data.ResultSmaller fish had more new muscle fiber numbers and wider intermuscular spaces compared to big specimens. …”
Get full text

Protocol for capturing a full transcriptome from single preimplantation embryos using So-Smart-seq by Chunyao Wei, Jeannie T. Lee

“…Summary: Strand-optimized Smart-seq (So-Smart-seq) can capture a comprehensive transcriptome from low-input samples. This technique detects both polyadenylated and non-polyadenylated RNAs, inclusive of repetitive RNAs, while excluding highly abundant ribosomal RNAs. …”
Get full text

Integrated metabolomic and transcriptomic analysis of Pogostemon cablin shed new light on the complete biosynthesis pathway of pogostone by Sen Wang, Zhaoqi Zeng, Zhaoqi Zeng, Qi Zhang, Wenhua Liu, Qinjian Liu, Chong Xie, Chong Xie, Jinlong Bei, Bingxian Chen, Aixia Zhang

“…Patchoulol analogs like patchoulene and germacrene mainly accumulated in leaf, while pogostone content was much higher in root. …”
Get full text

De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets. by Jeremy V Camp, Thomas L Svensson, Alexis McBrayer, Colleen B Jonsson, Peter Liljeström, Carl E Bruder

“…To enable de novo identification of transcriptionally active ferret genes in response to infection, we performed de-novo transcriptome sequencing of animals infected with H1N1 A/California/07/2009. …”
Get full text

The integrated analysis of transcriptomics and metabolomics reveals the effects of tea polyphenols on lipid metabolism in lion-head geese by Zhiqi Fu, Chunpeng Liu, Tao Zeng, Yuchuan Wang, Yuwen Liang, Na Ao, Lizhi Lu, Jing Fu

“…The control group received a basal diet, while the experimental group was supplemented with 1000 mg/kg of tea polyphenols (50.4 % catechin purity) in the basal diet for 18 weeks. …”
Get full text

The mechanism underlying B-cell developmental dysfunction in Kawasaki disease based on single-cell transcriptomic sequencing by Qiuping Lin, Zhen Wang, Guohui Ding, Guang Li, Liqin Chen, Qingzhu Qiu, Sirui Song, Wei Liu, Xunwei Jiang, Min Huang, Min Huang, Libing Shen, Tingting Xiao, Lijian Xie, Lijian Xie, Lijian Xie

Get full text

Transcriptomic signatures of WNT-driven pathways and granulosa cell-oocyte interactions during primordial follicle activation. by Hinako M Takase, Tappei Mishina, Tetsutaro Hayashi, Mika Yoshimura, Mariko Kuse, Itoshi Nikaido, Tomoya S Kitajima

“…Our data revealed immediate transcriptomic changes in GCs post-PFA in Wls cKO mice, leading to a divergent trajectory, while oocytes exhibited modest transcriptomic alterations. …”
Get full text

Transcriptomics Analysis of Penicillium expansum ΔWSC1 Infection and Defense Mechanism against It in Pear Fruits by ZHAO Lina, HU Yize, SHU Yuling, Solairaj DHANASEKARAN, ZHANG Xiaoyun, YANG Qiya, ZHANG Hongyin

“…To analyze the role of the WSC1 gene in the pathogenic process of this fungal pathogen, we conducted transcriptomic analysis of a WSC1 knockout (ΔWSC1) strain. …”
Get full text

De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii by Valentina Mastrantonio, Daniele Porretta, Franco Liberati, Roberta Bisconti, Tiziana Castrignanò, Daniele Canestrelli

“…Here, we present the first de novo transcriptomes of the sea-rock pools mosquitoes Aedes mariae and Aedes zammitii, two species adapted to highly variable habitats. …”
Get full text

Enhancing growth performance in Liangshan black sheep through fermented onion: insights from transcriptomics and metabolomics by Chaoyun Yang, Shuzhe Wang, Yunxia Qi, Yadong Jin, Ran Guan, Zengwen Huang

“…Rumen epithelial tissue was then collected for transcriptome sequencing, while fermented and unfermented onions were collected for untargeted metabolomics. …”
Get full text

Cross modality learning of cell painting and transcriptomics data improves mechanism of action clustering and bioactivity modelling by Son V. Ha, Steffen Jaensch, Maciej M. Kańduła, Dorota Herman, Paul Czodrowski, Hugo Ceulemans

“…While multimodal learning of chemical structure-cell painting, or different omics data has been experimented; a cell painting-bulk transcriptomics multimodal model is still unexplored. …”
Get full text

De novo transcriptome sequencing and analysis of male, pseudo-male and female yellow perch, Perca flavescens. by Yan-He Li, Han-Ping Wang, Hong Yao, Paul O'Bryant, Dean Rapp, Liang Guo, Eman A Waly

“…In this study, we performed the de novo assembly of yellow perch gonads and muscle transcriptomes by high throughput Illumina sequencing. …”
Get full text

Transcriptome and translatome profiling of Col-0 and grp7grp8 under ABA treatment in Arabidopsis by Jing Zhang, Yongxin Xu, Jun Xiao

Get full text

Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent. by Fang-Chao Zhu, Jin Sun, Guo-Yong Yan, Jiao-Mei Huang, Chong Chen, Li-Sheng He

“…S. leurokolos inhabits the central area closer to the active chimney, while A. longirostris inhabits the peripheral area. …”
Get full text