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161
Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis.
Published 2025-01-01“…<h4>Methods</h4>Ferroptosis-related genes were identified from UC microarray data extracted from the GEO database and FerrDb. …”
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162
iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Published 2013-01-01“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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163
Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts
Published 2019-01-01“…Although the molecular mechanisms underlying osteoclastogenesis have been well established, the means by which OCs maintain their survival during OC development remain unknown. …”
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164
Androgen Modulates Functions of Endothelial Progenitor Cells through Activated Egr1 Signaling
Published 2016-01-01“…Moreover, microarray analysis was performed to explore how DHT changes the gene expression profiles of EPCs. …”
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165
A framework for the establishment of a cnidarian gene regulatory network for "endomesoderm" specification: the inputs of ß-catenin/TCF signaling.
Published 2012-01-01“…We show both evolutionary conserved as well as profound differences in endomesodermal GRN structure compared to bilaterians that may provide fundamental insight into how GRN subcircuits have been adopted, rewired, or co-opted in various animal lineages that give rise to specialized endomesodermal cell types.…”
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166
Ectopic repression of receptor tyrosine kinase–like orphan receptor 2 inhibits malignant transformation of ovarian cancer cells by reversing epithelial–mesenchymal transition
Published 2017-04-01“…Knockdown of receptor tyrosine kinase–like orphan receptor 2 inhibited ovarian cancer cell proliferation, migration, invasion, and induced morphologic as well as digestive state alterations in stably transfected SKOV3 cells. …”
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167
The Neural Progenitor Cell-Associated Transcription Factor FoxG1 Regulates Cardiac Epicardial Cell Proliferation
Published 2024-01-01“…In cultured epicardial cells, shRNA-mediated FoxG1 knockdown significantly decreased cell proliferation, as well as Snord116 expression. Our results demonstrate that FoxG1 regulates epicardial proliferation, and suggest it may affect cardiac remodeling.…”
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168
The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis.
Published 2016-01-01“…<h4>Background</h4>Mycobacterium tuberculosis infection is a leading cause of infectious death worldwide. Gene-expression microarray studies profiling the blood transcriptional response of tuberculosis (TB) patients have been undertaken in order to better understand the host immune response as well as to identify potential biomarkers of disease. …”
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169
Identifying the molecular association between diabetic nephropathy and hepatocellular carcinoma: an network biology approach
Published 2025-05-01“…In conclusion, the hub genes identified in the present study can be further explored as promising biomarkers for prognosis and diagnosis in DN and HCC, as well as therapeutic interventions.…”
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170
Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling
Published 2021-03-01“…Activation of this pathway was seen in tissue microarray analysis on prostatectomy tissues and patient‐derived xenografts. …”
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171
TLR3 Plays Significant Roles against HBV-Associated HCC
Published 2015-01-01“…The role of TLR3 in hepatocellular carcinoma (HCC) with hepatitis B virus (HBV) infections is not well understood. To investigate the ability of TLR3 in regulating HBV replication in HCC, 80 cases of human HCC were collected and their tissue microarray was made. …”
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172
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring.
Published 2008-04-01“…Global DNA methylation, methylated DNA immunoprecipitation followed by CGI(2) microarray profiling and bisulfite sequencing, as well as quantitative real-time RT-PCR gene expression analysis, were evaluated in hippocampal pyramidal neurons excised by laser capture microdissection. …”
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173
Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
Published 2014-01-01“…These sphingolipids not only play a structural role in lipid membranes, but some are also intracellular and intercellular signaling molecules important in normal eukaryotic cell functions as well as orchestrating immune responses. The members of the SphR transcriptome were identified by microarray analyses, and DNA binding assays showed specific interaction of these promoters with SphR, which enabled us to determine the consensus SphR binding site. …”
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174
FOSB is a key factor in the genetic link between inflammatory bowel disease and acute myocardial infarction: multiple bioinformatics analyses and validation
Published 2025-04-01“…The genetic mechanisms underlying this link are not well understood. Methods We downloaded IBD and AMI-related microarray datasets from the NCBI Gene Expression Omnibus (GEO) database. …”
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175
MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis
Published 2025-05-01“…The relationship between serum MFAP4 levels and liver fibrosis, as well as prognosis, was investigated using ROC curve analysis. …”
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176
Transcriptional regulation by CHIP/LDB complexes.
Published 2010-08-01“…Here we use the powerful genetics of Drosophila combined with microarray and bioinformatics analyses to tackle this challenge. …”
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177
Regulation of Myogenesis by MechanomiR-200c/FoxO3 Axis
Published 2025-06-01“…However, the underlying molecular mechanisms are not well understood. Here, we report that mechanical stretch inhibits the differentiation of mouse primary myoblasts by promoting the cell cycle program and by inhibiting the expression of the myogenic regulator MyoD. …”
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178
Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.
Published 2010-10-01“…Interestingly, meta-analysis of microarray data in the Geo and Oncomine databases suggests that Zip4 mRNA may also be elevated in many types of cancer. …”
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179
Fecal carriage of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae after urinary tract infection - A three year prospective cohort study.
Published 2017-01-01“…Stool samples were cultured directly on ChromID ESBL agar as well as in an enrichment broth, and culture positive isolates were examined by blaCTX-M multiplex PCR. …”
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180
Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b.
Published 2014-01-01“…These observations were further supported by an enrichment of genes in the downstream NF-κB Signalling pathway as well as an up regulation of genes with pro-apoptotic functions post-challenge. …”
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