Directional genomic hybridization (dGH™) identifies small inverted duplications in situ by Thomas Liehr, Erin Cross, Stefanie Kankel

“…However, this latter approach seems principally well-suited to distinguish small, tandem inverted duplications from direct duplications in clinical cases. …”
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General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles by Yongliang Yang, S. James Adelstein, Amin I. Kassis

“…As control tests, a number of well-known cancer imaging targets were detected and confirmed by our study. …”
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MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. by Ashley M Miller, Derek S Gilchrist, Jagtar Nijjar, Elisa Araldi, Cristina M Ramirez, Christopher A Lavery, Carlos Fernández-Hernando, Iain B McInnes, Mariola Kurowska-Stolarska

“…Using miRNA target prediction algorithms and the microarray transcriptomic profile of miR-155(-/-) livers, we identified and validated that Nr1h3 (LXRα) as a direct miR-155 target gene that is potentially responsible for the liver phenotype of miR-155(-/-) mice. …”
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Large-scale gene expression data clustering through incremental ensemble approach by Imran Khan, Abdul Khalique Shaikh, Naresh Adhikari

“…DNA microarray technology monitors gene activity in real-time in living organisms. …”
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A Synopsis of Serum Biomarkers in Cutaneous Melanoma Patients by Pierre Vereecken, Frank Cornelis, Nicolas Van Baren, Valérie Vandersleyen, Jean-François Baurain

“…New serum biomarkers of melanoma progression and metastatic disease are still awaited in order to provide efficient rationale for followup and treatment choices. LDH as well as S100B levels have been correlated with poor prognosis in AJCC stage III/IV melanoma patients. …”
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Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation. by Lisa Y Pang, Emma L Gatenby, Ayako Kamida, Bruce A Whitelaw, Ted R Hupp, David J Argyle

“…Here we report the successful isolation of CSCs from primary canine osteosarcoma, as well as established cell lines. We show that these cells can form tumourspheres, and demonstrate relative resistance to chemotherapy. …”
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Immunohistochemistry guided segmentation of benign epithelial cells, in situ lesions, and invasive epithelial cells in breast cancer slides. by Maren Høibø, André Pedersen, Vibeke Grotnes Dale, Sissel Marie Berget, Borgny Ytterhus, Cecilia Lindskog, Elisabeth Wik, Lars A Akslen, Ingerid Reinertsen, Erik Smistad, Marit Valla

“…The sections were derived from four breast cancer cohorts. Tissue microarray cores from a fifth cohort of 21 patients was used as a second test set. …”
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An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface. by Pamela A Tamez, Souvik Bhattacharjee, Christiaan van Ooij, N Luisa Hiller, Manuel Llinás, Bharath Balu, John H Adams, Kasturi Haldar

“…Here, we combined bioinformatics and genome-wide expression analyses with a new series of transgenic and cellular assays to show for the first time in malaria parasites that microarray read out from a chemical perturbation can have predictive value. …”
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Transcriptomic characterization of temperature stress responses in larval zebrafish. by Yong Long, Linchun Li, Qing Li, Xiaozhen He, Zongbin Cui

“…Previous studies have identified many temperature-regulated genes in adult tissues; however, the transcriptional responses of fish larvae to temperature stress are not well understood. In this study, we characterized the transcriptional responses in larval zebrafish exposed to cold or heat stress using microarray analysis. …”
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Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G‐protein action by Sona Pandey, Rui‐Sheng Wang, Liza Wilson, Song Li, Zhixin Zhao, Timothy E Gookin, Sarah M Assmann, Réka Albert

“…Here, we generate and analyze microarray data from guard cells and leaves of G‐protein subunit mutants of the model plant Arabidopsis thaliana, with or without treatment with the stress hormone, abscisic acid. …”
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Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia. by Ignat Drozdov, Bernhard Svejda, Bjorn I Gustafsson, Shrikant Mane, Roswitha Pfragner, Mark Kidd, Irvin M Modlin

“…High throughput techniques such as inference of gene regulatory networks from microarray experiments can objectively define signaling machinery in this disease. …”
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Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma by Jun-xing Liu, Ting Lu, Yin Xia, Jun Yang, Ying-feng Jiang, Yan Zhao, Hong Yu

“…Abstract Backgroud In the previous era of functional genomics, it was widely believed that the expression levels of housekeeping genes (HKGs) remained relatively constant and were unaffected by variations in tissue type, cell development stage, cell cycle state, as well as internal and external cellular environments. …”
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mRNA ratios of AR to ESR1 and PGR distinguish breast cancer subtypes based on public datasets and experimental models by Diego Prieto, Milena Rondón-Lagos, Paola Cruz-Tapias, Andrés Rincón-Riveros, Wilson Rubiano, Jairo De la Peña, Elizabeth Vargas, Victoria E. Villegas, Nelson Rangel

“…Here, we conducted a meta-analysis of large-scale microarray transcriptomic datasets to evaluate whether the mRNA expression levels of the androgen receptor gene, relative to those of the estrogen receptor gene (AR/ESR1 ratio) and the progesterone receptor gene (AR/PGR ratio), can help differentiate BC tumor subtypes. …”
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Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature by Miriam Wittmann, Edward M Vital, Mohammad Shalbaf, Adewonuola A Alase, Anna Berekmeri, Md Yuzaiful Md Yusof, Jelena Pistolic, Mark J Goodfield, Sara Edward, Natalia V Botchkareva, Martin Stacey

“…RNA was isolated from plucked anagen HFs and microarray, as well as quantitative real-time PCR was performed.Results Here, we report that gene expression analysis of only a small number of HF plucked from lesional areas of the scalp is sufficient to differentiate CDLE from psoriasis lesions or healthy HF. …”
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The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus–positive and –negative oropharyngeal squamous cell carcinoma by Hesham Mohamed, Jaana Hagström, Lauri Jouhi, Timo Atula, Alhadi Almangush, Antti Mäkitie, Caj Haglund

“…The Bmi-1 oncogene is a well-known member of the mammalian polycomb-group family. …”
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Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1. by Jessica LaRocca, Jodie Pietruska, Mary Hixon

“…Retroviral-mediated shRNA knockdown of Akt1 and Btn1a1 in MCF-7 human breast epithelial further illustrated the importance of Akt1 in mammary epithelial cell proliferation, as well as in the regulation of Btn1a1 and subsequent expression of ß-casein, a gene that encodes for milk protein. …”
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MOLECULAR AND GENETIC INSIGHTS OF ROOT-KNOT NEMATODES PATHOGENICITY: A REVIEW by Prabina Bhandari, Anjali Thapa, Anusha Ghimire, Sunil Ojha, Srijana Saud, Sanju Aryal

“…Much research is being done on molecular mechanisms underlying interactions between plants and nematodes as well how plants react to various invasive diseases.…”
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Characteristic expression profile of small nucleolar RNAs and their association with tumor immune microenvironment in papillary thyroid carcinoma by Qi-Lan Jiang, Fu-Yi Wang, Yuan Men, Yi-Huan Wu, Qin Xu, Yang Zeng, Jun Jiang

“…In this study, we employed small RNA microarray analysis to profile snoRNA expression in tumor tissues and corresponding normal thyroid tissues obtained from patients undergoing thyroidectomy. …”
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MicroRNA Regulation of Brain Tumour Initiating Cells in Central Nervous System Tumours by Neha Garg, Thusyanth Vijayakumar, David Bakhshinyan, Chitra Venugopal, Sheila K. Singh

“…Special attention is paid to two highly aggressive and well-characterized brain tumours: gliomas and medulloblastoma. …”
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Cell cycle regulation and cytoskeletal remodelling are critical processes in the nutritional programming of embryonic development. by Angelina Swali, Sarah McMullen, Helen Hayes, Lorraine Gambling, Harry J McArdle, Simon C Langley-Evans

“…By using a cross-over design of two well established models of maternal protein and iron restriction we aimed to identify putative common "gatekeepers" which may drive nutritional programming.Both protein and iron deficiency in utero reduced the nephron complement in adult male Wistar and Rowett Hooded Lister rats (P<0.05). …”
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