Differential gene expression analysis in patients with primary hyperhidrosis by Ting Pu, Muhammad Ameen Jamal, Muhammad Nauman Tahir, Salman Ullah, Maher Un Nisa Awan, Asif Shahzad, Faisal Mahmood

“…Of four genes, the expression of three genes, i.e., TMEM16A, ITPR2 and FOXA1, was found to be significantly high in the primary hyperhidrosis patients, whereas low expression of the gene AQP5 was noted compared to that of the control samples. Microarray data analysis on anhidrosis was done using GEO2R database as well as the anhidrosis datasets available on Gene Exression Omnibus (GEO). …”
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LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancer by Xi Qiao, Johannes Routila, Mari Tienhaara, Heikki Irjala, Priyadharshini Parimelazhagan Santhi, Teemu Huusko, Linda Nissi, Ilkka Paatero, Noora Lehtinen, Juha Rantala, Toni Viljanen, Ilmo Leivo, Petri Koivunen, Anna Jouppila-Mättö, Rami Taulu, Leif Bäck, Tommy Wilkman, Eeva Haapio, Ilpo Kinnunen, Kari Kurppa, Jukka Westermarck, Sami Ventelä

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The Genetics of 241 Fetuses With Talipes Equinovarus: A 8‐Year Monocentric Retrospective Study by Pingshan Pan, Dongbing Huang, Jiangxuan Wei, Wei He, Peng Huang, Sheng Yi, Jing Huang, Dahua Meng, Shuyin Tan, Xinyan Li, Hongwei Wei, Linlin Wang

“…ABSTRACT Objective This study aims to investigate the utility of chromosomal microarray analysis (CMA) and whole exome sequencing (WES) in fetuses diagnosed with talipes equinovarus (TE), as well as to explore the genetic factors contributing to TE. …”
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HMGB1 Deficiency Occurs in a Broad Range of Human Cancers and Is Often Associated with Unfavorable Tumor Phenotype by Viktoria Chirico, Hena Sharifi, Maria Christina Tsourlakis, Seyma Büyücek, Clara Marie von Bargen, Katharina Möller, Florian Lutz, David Dum, Martina Kluth, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Piero Caneve, Maximilian Lennartz, Morton Freytag, Sebastian Dwertmann Rico, Simon Kind, Viktor Reiswich, Eike Burandt, Till S. Clauditz, Patrick Lebok, Christoph Fraune, Till Krech, Sarah Minner, Andreas H. Marx, Waldemar Wilczak, Ronald Simon, Guido Sauter, Stefan Steurer, Kristina Jansen

“…<b>Methods</b>: To better comprehend the role of HMGB1 expression in cancer, a tissue microarray containing 14,966 samples from 134 different tumor entities and 608 samples of 76 different normal tissue types was analyzed by immunohistochemistry. …”
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Predicting Tolerance to Cow’s Milk Allergy in Children Using IgE and IgG4 Peptide Binding Profiles by Carlos Fernández-Lozano, Sergio Olmos-Piñero, Laura Sánchez-Ruano, Soledad Terrados, Mª del Carmen Diéguez, Montserrat Fernández-Rivas, Cristina Vlaicu, Inmaculada Cerecedo, Alejandro Gonzalo-Fernandez, Belén de la Hoz, Javier Martínez-Botas

“…We investigated specific IgE and IgG4 binding to sequential epitopes of the five major CM allergens (α-s1-, α-s2-, β-, and κ-caseins as well as β-lactoglobulin) using a microarray-based immunoassay. …”
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The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo by Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei zhang

“…The expression levels of these four genes, as well as their corresponding proteins, were subsequently confirmed using RT-qPCR and western blot analysis, respectively. …”
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Outcomes associated with fetal nuchal translucency between 3.0 and 3.4 mm in the first trimester by Manon D. E. Vriendt, Caroline Rooryck, Hugo Madar, Frédéric Coatleven, Marie Vincienne, Perrine Prier, Sophie Naudion, Loïc Sentilhes, Hanane Bouchghoul

“…The literature suggests an increased risk of chromosomal aberration, as well as pathogenic copy number variations (CNVs) on chromosomal microarray, for fetuses with NT between 3.0 and 3.4 mm. …”
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First African case report of hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome due to inverted duplication and deletion of chromosome 10p by Tumelo M. Satekge, Glenrose Rikhotso, Bianca Rossouw, Bronwyn Dillon, Fiona Baine-Savanhu

“…Here, we report the first African case of HDR syndrome to be confirmed by chromosomal microarray analysis (CMA). Case presentation A 3-month-old female presented with focal seizures due to severe hypocalcaemia associated with low parathyroid hormone. …”
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Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella by Arlo Z. Randall, Valentino Conti, Usman Nakakana, Xiaowu Liang, Andy A. Teng, Antonio Lorenzo Di Pasquale, Melissa Kapulu, Robert Frenck, Odile Launay, Pietro Ferruzzi, Antonella Silvia Sciré, Elisa Marchetti, Christina Obiero, Jozelyn V. Pablo, Joshua Edgar, Philip Bejon, Adam D. Shandling, Joseph J. Campo, Angela Yee, Laura B. Martin, Audino Podda, Francesca Micoli

“…Responses to several microarray antigens correlated well with S. sonnei LPS serum IgG antibody levels. …”
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Aberrant glycosylation patterns as potential biomarkers for diagnosis and disease progression in bullous pemphigoid by Haijun Miao, Jundan Yang, Yaxing Bai, Shengxian Shen, Xia Li, Lixin Yue, Gang Wang, Erle Dang

“…In this study, we explored the molecular mechanisms of abnormal glycosylation in BP pathogenesis.MethodsWe systematically investigated the glycosylation changes in serum, blister fluid, and saliva from BP patients using lectin microarray assays and lectin-based enzyme-linked immunosorbent assays.ResultsOur findings revealed increased glycosylation modifications of sialic acid, galactose, and fucose in serum proteins from BP patients, as well as enhanced fucosylation, galactosylation, and biantennary N-glycan glycosylation in blister fluid proteins. …”
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A Novel Gene Expression Scoring System Predicts Recurrence in Non‐Muscle‐Invasive Bladder Cancer Patients by Emina Kayama, Motohide Uemura, Akifumi Onagi, Satoru Meguro, Soichiro Ogawa, Kei Yaginuma, Kanako Matsuoka, Seiji Hoshi, Tomoyuki Koguchi, Junya Hata, Yuichi Sato, Hidenori Akaihata, Reiko Honma, Shinya Watanabe, Yoshiyuki Kojima

“…Methods NMIBC and normal bladder samples were subjected to microarray analysis to obtain gene expression profiles. …”
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Decreased mitochondrial‐related gene expression in adipose tissue after acute sprint exercise in humans: A pilot study by Mona Esbjörnsson, Håkan C. Rundqvist, Barbara Norman, Ted Österlund, Eric Rullman, Jens Bülow, Eva Jansson

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Laryngeal Squamous Cell Carcinoma Is Characterized by a Stronger Expression of Nectin-4 Compared to Nectin-2 by Matej Maršić, Nives Jonjić, Maja Gligora Marković, Svjetlana Janković, Marko Velepič, Ilinko Vrebac, Lara Batičić, Tamara Braut

“…A retrospective study was conducted on tissue microarray (TMA) samples derived from 31 patients who underwent total laryngectomy. …”
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Serum/glucose starvation enhances binding of miR-4745-5p and miR-6798-5p to HNRNPA1 mRNA 3ʹUTR: A novel method to identify miRNAs binding to mRNA 3ʹUTR using λN peptide-boxB sequen... by Tetsuyuki Takahashi, Mai Funamura, Shun Wakai, Takao Hijikata

“…However, the mechanisms driving hnRNP A1 downregulation during serum/glucose starvation are not yet well understood. Using the novel interaction between the λN peptide and boxB sequence (λN/boxB system) and miRNA microarray analysis, we aimed to identify specific-binding microRNAs (miRs or miRNAs) targeting HNRNPA1 mRNA 3ʹUTR under serum/glucose-starved conditions. …”
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Cold-inducible RNA-binding protein is associated with subtype-specific breast cancer patient outcomes by Matthew Dankner, Veronique Ouellet, Jakob Lafon, Rima Ezzeddine, Matthew G. Annis, Afnan Abu-Thuraia, Quebec Breast Cancer Foundation Tissue Microarray Consortium, Peter M. Siegel

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Evaluation of gene expression classification studies: factors associated with classification performance. by Putri W Novianti, Kit C B Roes, Marinus J C Eijkemans

“…Classification methods used in microarray studies for gene expression are diverse in the way they deal with the underlying complexity of the data, as well as in the technique used to build the classification model. …”
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Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods by Mark Burton, Mads Thomassen, Qihua Tan, Torben A. Kruse

“…This study compares the performance of seven classification methods and the effect of voting for predicting metastasis outcome in breast cancer patients, in three situations: within the same dataset or across datasets on similar or dissimilar microarray platforms. Combining classification results from seven classifiers into one voting decision performed significantly better during internal validation as well as external validation in similar microarray platforms than the underlying classification methods. …”
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Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells. by Swojani Shrestha, Sandeep Singhal, Donald A Sens, Seema Somji, Bethany A Davis, Rachel Guyer, Spencer Breen, Matthew Kalonick, Scott H Garrett

“…One of the serious complications of high glucose levels is diabetic nephropathy. The preliminary microarray study performed on primary human renal tubular epithelial (hRTE) cells exposed to high glucose levels showed a significant downregulation of mTOR as well as its associated genes as well as lysosomal genes. …”
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ChIP-chip designs to interrogate the genome of Xenopus embryos for transcription factor binding and epigenetic regulation. by Robert C Akkers, Simon J van Heeringen, J Robert Manak, Roland D Green, Hendrik G Stunnenberg, Gert Jan C Veenstra

“…<h4>Background</h4>Chromatin immunoprecipitation combined with genome tile path microarrays or deep sequencing can be used to study genome-wide epigenetic profiles and the transcription factor binding repertoire. …”
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Gene Expression Music Algorithm-Based Characterization of the Ewing Sarcoma Stem Cell Signature by Martin Sebastian Staege

“…Gene Expression Music Algorithm (GEMusicA) is a method for the transformation of DNA microarray data into melodies that can be used for the characterization of differentially expressed genes. …”
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