Adrenocortical carcinoma survival gene HMMR was identified as being targeted by fluorouracil and epirubicin using a gene coexpression network-based drug repositioning strategy by Zahra Jafari, Seyed-Morteza Javadirad, Seyede Elmira Yazdi Rouholamini

“…Hub genes were identified using weighted correlation network analysis (WGCNA), and their differential expression was confirmed by microarrays and RNA sequencing. Hub genes were analyzed in more depth for enrichment, coexpression, and protein–protein interaction. …”
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Outcomes Associated With ABCG2 and CD133 Expression in Patients With Gastric Cancer After Surgical Resection by Donghoon Kang, Jae Myung Park, Sung Hak Lee, Yu Kyung Cho, Bo-In Lee, Myung-Gyu Choi

“…Methods ABCG2 and CD133 expression levels were analyzed, using immunohistochemistry and tissue microarrays, in tumor samples from 459 patients who underwent surgical resections due to gastric cancer. …”
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CD44 Immunohistochemical Expression in Central and Peripheral Parts of Prostatic Adenocarcinoma: An Institutional Study by Romano Oguic, Antun Grskovic, Josip Spanjol, Ivana Mikolasevic, Gordana Djordjevic

“…Also hypothetically, they indicate a protective role of CD44s in a group of well-differentiated tumors at the periphery of the tumor mass. …”
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Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma by Qing Yuan, Song‐Quan Wang, Guang‐Tao Zhang, Jie He, Zhi‐Dan Liu, Ming‐Rong Wang, Hong‐Qing Cai, Jing‐Hai Wan

“…Further, we validated the expression and the survival prediction role of SERPINA3 by using tissue microarrays and RNAscope in situ hybridization in 321 gliomas. …”
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Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy by Eithar Mohamed, Sara Goodman, Leah Cooksey, Daniel M. Fletcher, Olivia Dean, Viktoriya B. Boncheva, Ken I. Mills, Kim H. Orchard, Barbara-ann Guinn

“…Methods: aB-ALL antigens were identified using different sources—immunoscreening, protoarrays, two microarrays and one cancer-testis antigen database, and a review of the genomic analyses of aB-ALL. …”
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Decoding the prognostic landscape of LUAD: the interplay between N6-methyladenosine modification and immune microenvironment by Quan Chen, Quan Chen, Weijun Wan, Qing Zhao, Juan Li, Juan Li, Yanli Xiong, Yanli Xiong, Yuchuan Yuan, Lu Tang, Xiaofeng Wu, Wei Xing, Wei Guo, Di Lu, Luoquan Ao, Xiang Xu, Xiang Xu, Xiang Xu, Xiang Ao, Xiang Ao, Xiang Ao

“…BackgroundTo determine the role of N6-methyladenosine (m6A) modification in the tumor immune microenvironment (TIME), as well as their association with lung adenocarcinoma (LUAD).MethodsConsensus clustering was performed to identify the subgroups with distinct immune or m6A modification patterns using profiles from TCGA. …”
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Characterization of tumor-infiltrating lymphocytes and their spatial distribution in triple-negative breast cancer by Eunkyung Han, Hye Yeon Choi, Hyun Jung Kwon, Yul Ri Chung, Hee-Chul Shin, Eun-Kyu Kim, Koung Jin Suh, Se Hyun Kim, Jee Hyun Kim, So Yeon Park

“…These findings emphasize the importance of CTLs and NK cells as well as the spatial uniformity of TIL infiltration in clinical outcome of TNBC patients, providing valuable insights for refining prognostic assessments and guiding immunotherapeutic strategies.…”
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Elucidation of Dysregulated Pathways Associated With Hypoxia in Oestrogen Receptor‐Negative Breast Cancer by Suad A. K. Shamis, Jean Quinn, Sara Al‐Badran, Molly McKenzie, Phimmada Hatthakarnkul, Gerard Lynch, Guang‐Yu Lian, Warapan Numprasit, Laszlo Romics Jr., Ditte Andersen, Elizabeth Mallon, Donald C. McMillan, Joanne Edwards

“…ABSTRACT Purpose Carbonic anhydrase IX (CAIX) is a well‐established prognostic marker in breast cancer (BC). …”
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Quantitative and Qualitative Variations in TILs in Risk Stratification and Patient Selection for Neoadjuvant Chemotherapy of the Luminal B and Triple-Negative Breast Cancer Immunop... by Ana Car Peterko, Koraljka Rajković Molek, Anita Savić Vuković, Tamara Gulić, Petra Valković Zujić, Eleonora Cini Tešar, Damir Juranić, Aleksandra Pirjavec Mahić, Franjo Lovasić, Gordana Đorđević, Manuela Avirović

“…Quantitative and qualitative evaluations of TILs (Tumor-Infiltrating Lymphocytes) were performed on tissue microarrays constructed from pretreatment core-needle biopsy tumor specimens. …”
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Identification of a Serum Exosome-Derived lncRNA‒miRNA‒mRNA ceRNA Network in Patients with Endometriosis by Yan Huang, Deyu Zhang, Yingfang Zhou, Chao Peng

“…Exosomal miRNA was sequenced using microarrays. EM-related differential miRNAs (DE-miRNAs) were identified using analysis of differential miRNA expression and weighted coexpression network analysis. …”
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Non-viral HCC miRNA profiling reveals miR-1972 as a potential positive prognostic marker by Venkata Ramana Mallela, Marie Rajtmajerová, Esraa Ali, Lenka Červenková, Andriy Trailin, Petr Hošek, Richard Pálek, Ondřej Daum, Václav Liška, Kari Hemminki, Filip Ambrozkiewicz

“…Methods: We conducted microRNA profiling by microarrays in 45 paired (tumor and non-tumor adjacent tissue) samples from non-viral HCC patients. …”
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Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…Methods Apolipoprotein E knockout (ApoE KO) mice were exposed to DE or filtered air (FA) for two weeks, or DE for two weeks followed by FA for 1 week. Expression microarrays and global metabolomics assessment were performed in the liver. …”
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LIPID PROFILE AND GENETIC MARKERS ASSOCIATED WITH THE LEVEL OF OXIDIzED LOW DENSITY LIPOPROTEIDES by E. Yu. Khlebus, А. N. Meshkov, V. Z. Lankin, А. A. Orlovsky, А. V. Kiseleva, N. V. Shcherbakova, А. А. Zharikova, А. I. Ershova, А. К. Tikhaze, Е. B. Yarovaya, I. Е. Chazova, S. А. Boytsov

“…The oxLDL level depends on the level of LDL-C and ApoB-100 in blood, as well as on the genetic susceptibility — a combination of the SNP of APOB gene.…”
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The role of the aging process and related factor EMP1 in promoting progression of resectable pancreatic cancer by Junfeng Zhang, Jianyou Gu, Tao Zhang, Renpei Xia, Jianbo Li, Mingda Tan, Yongjun Yang, Jifeng Xiang, Bin Xie, Rong Tang, Wangge Li, Xianxing Wang, Shixiang Guo, Huaizhi Wang

“…We employed lentiviral vectors for both knockdown and overexpression of EMP1 in Panc02 cells, followed by the establishment of subcutaneous, pulmonary metastasis, and orthotopic pancreatic liver metastasis models in mice. Using tissue microarrays, we evaluated the expression of EMP1 and its downstream entities, and then conducted clinical correlation analysis. …”
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Inhibition of PDK modulates radiotherapy resistance in gastric cancer by Qi Zhang, Wanjia Qiao, Xiaoyu Liu, Jun Lu, Farooq Benish, Shuping Li, Xiaojun Liu

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