Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells by Noriko Goto, Katsumi Fujimoto, Sakiko Fujii, Hiroko Ida-Yonemochi, Hayato Ohshima, Takeshi Kawamoto, Mitsuhide Noshiro, Chisa Shukunami, Katsuyuki Kozai, Yukio Kato

“…Interestingly, DNA microarray and PCR analyses revealed that MSX1 knockdown induced the sterol regulatory element-binding protein 2 (SREBP2) transcriptional factor and its downstream target genes in the cholesterol synthesis pathway. …”
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Placental malaria induces a unique methylation profile associated with fetal growth restriction by Nida Ozarslan, Corina Mong, John Ategeka, Lin Li, Sirirak Buarpung, Joshua F. Robinson, Jimmy Kizza, Abel Kakuru, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal, Stephanie L. Gaw

“…Fetal growth restriction (FGR) is associated with perinatal death and adverse birth outcomes, as well as long-term complications, including increased childhood morbidity, abnormal neurodevelopment, and cardio-metabolic diseases in adulthood. …”
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Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway by Xiao Li, Mengna Cui, Long Xu, Qie Guo

“…We intended to explore the mechanisms underlying the development of sorafenib resistance, therefore identifying an effective strategy to overcome sorafenib resistance remain challenges.MethodsHere, the follow-up of liver cancer patients undergoing sorafenib therapy, as well as animal tumor challenge and treatment were performed. …”
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Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics... by Ziwei Gong, Rong Cao, Hong Zhu

“…In MS peripheral blood microarray data, CD40 is significantly downregulated in RRMS. …”
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Characterizing Methicillin-Resistant <i>Staphylococcus</i> spp. and Extended-Spectrum Cephalosporin-Resistant <i>Escherichia coli</i> in Cattle by Lisa Abdank, Igor Loncaric, Sascha D. Braun, Elke Müller, Stefan Monecke, Ralf Ehricht, Reinhild Krametter-Frötscher

“…For this reason, milk and nasal samples were examined for the presence of methicillin-resistant <i>Staphylococcus aureus</i> as well as fecal samples for extended-spectrum cephalosporin-resistant <i>Escherichia coli</i>. …”
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Exploration of biomarkers for predicting the prognosis of patients with diffuse large B-cell lymphoma by machine-learning analysis by Shifen Wang, Hong Tao, Xingyun Zhao, Siwen Wu, Chunwei Yang, Yuanfei Shi, Zhenshu Xu, Dawei Cui

“…To improve this situation, it is urgent to explore disease-specific diagnostic biomarkers and mechanisms. Methods Three microarray datasets (GSE25638, GSE12195 and GSE12453) were downloaded from the Gene Expression Omnibus (GEO) database. …”
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Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invas... by Fereshteh Rezagholizadeh, Adel Salimi, Ali Sharifi-Zarchi, Farid Azmoudeh-Ardalan, Kazem Mousavizadeh, Fatemeh Tajik, Mahshid Panahi, Hossein Khorramdelazad, Masoud Baghai Wadji, Atefeh Kashanizadeh, Alireza Lotfalizadeh, Seyed Javad Mowla, Mohammad Taghi Joghataei

“…Immunohistochemistry (IHC) on 353 PDAC patients, including 73 PanIN lesions and 280 tumor tissues on tissue microarray (TMA) slides, provided further confirmation. …”
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Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line by Nancy Bueno Figueiredo, Sílvia Helena Cestari, Sandro José Conde, Renata Azevedo Melo Luvizotto, Maria Teresa De Sibio, Denise Perone, Maria Lúcia Hirata Katayama, Dirce Maria Carraro, Helena Paula Brentani, Maria Mitzi Brentani, Célia Regina Nogueira

“…It has been well established that estrogen plays an important role in the progression and treatment of breast cancer. …”
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Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period by Junwei Fan, Junwei Fan, Peihao Wen, Liyun Yuan, Yan Xia, Shijie Hu, Xiaoqing Zhang, Zhihai Peng, Zhihai Peng

“…All recipients and their corresponding donor livers from center 1 were genotyped using an Affymetrix DMET Plus microarray, and association analysis was performed using trough blood concentration/weight-adjusted-dose ratios (CDR, (ng/mL)/(mg/kg)). …”
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Single Center Characterization of a Cohort of Salivary Gland Carcinomas by Ria Winkelmann, Maja Weißgerber, Peter J. Wild, Julia Bein, Maximilian Fleischmann, Melanie Demes, Panagiotis Balermpas, Andreas Loth, Katrin Bankov, Jens von der Grün

“…We aimed to characterize the cohort of salivary gland cancers in our institute and generate a tissue microarray (TMA) with clinical data available for immunohistochemical analysis. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi, Dalia Ali, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez

“…Global gene expression profiling was conducted using the Agilent microarray platform, and data normalization and bioinformatics were performed using GeneSpring software. …”
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Expression and Prognostic Significance of PDIA3 in Cervical Cancer by Jing Zhang, Hui Li, Huling Li, Dandan Lin, Xiaoyan Wang, Kai Wang

“…To investigate the expression of protein disulfide isomerase A3 (PDIA3/ERP57) in cervical cancer and its clinical prognostic significance as well as its function and possible action mechanism in the progression of cervical cancer. …”
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miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma by Miriam Piccioni, Francesco Di Meo, Anna Valentino, Virginia Campani, Maddalena Arigoni, Mirella Tanori, Mariateresa Mancuso, Rossana Cuciniello, Marco Tomasetti, Federica Monaco, Gaia Goteri, Enrico P. Spugnini, Raffaele A. Calogero, Giuseppe De Rosa, Gianfranco Peluso, Alfonso Baldi, Stefania Crispi

“…These genes showed an opposite expression compared to miR-503 levels both in cells and in MM samples. Finally, microarray analysis indicated that miR-503 inhibition affected the expression of the well-known MM biomarkers: CXCL8, SERPINE1 and Osteopontin. …”
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The novel diagnostic markers for systemic lupus erythematosus and periodontal disease by Xuedi Cheng, Jinfeng Zhang, Jiali Hou, Xiaocui Han, Bin Han, Jun Zhou, Zhongjun Wang, Junzheng Wang

“…This study aims to explore common genetic markers in SLE and PD that hold diagnostic and therapeutic implications.MethodsMicroarray datasets for systemic lupus erythematosus (SLE) and periodontal disease (PD) were obtained from the Gene Expression Omnibus (GEO) database. …”
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Neurotoxicity of high-dose methotrexate in the treatment of non-Hodgkin’s lymphomas in children: clinical and genetic aspects by Z. K. Simavonyan, T. T. Valiev, A. L. Kashanina, V. V. Semenova, A. R. Zheleznyak, L. Serdan Ramos, A. Yu. Ikonnikova, T. V. Nasedkina

“…All patients underwent genetic testing by allelespecific hybridization on a biological microarray. The study material was DNA extracted from peripheral blood lymphocytes. …”
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A novel polypeptide encoded by circSPIRE1 promotes prostate cancer proliferation and migration by restraining the ubiquitin-dependent degradation of LRP5 by Jintao Hu, Juanyi Shi, Junjie Wang, Yunfei Xiao, Degeng Kong, Mingchao Gao, Tianlong Luo, Shizhong Xu, Zhihan Yuan, Xinyi Ma, Xueseng Dong, Jingang Huang, Cheng Liu, Kewei Xu

“…Methods RNA microarray identified circSPIRE1 in prostate cancer tissues. …”
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Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy) by K. Yu. Mukhin, O. A. Pylaeva, M. Yu. Bobylova, N. V. Freydkova, L. Yu. Glukhova, M. O. Abramov

“…Thus, treatment with rufinamide was effective in 19 (61.3 %) patients. Rufinamide was well tolerated by most of the patients. Side effects were observed in 6 (19 %) participants. …”
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Novel ANKRD17 variants implicate synaptic and mitochondrial disruptions in intellectual disability and autism spectrum disorder by Dan Xia, Yuanyuan Xu, Zhanwen He, Rui Chen, Xiaoqin Xiao, Xiaojuan Li, Kewen Deng, Shuyun Deng, Lina Zhang, Jieming Zhang, Xiaofang Peng, Zhe Meng, Ruohao Wu, Dilong Wang, Zulin Liu, Hui Chen, Lu Li, Liyang Liang

“…Using trio whole-exome sequencing (Trio-WES) and chromosomal microarray analysis (CMA), we identified two unrelated cases with novel de novo heterozygous ANKRD17 variants. …”
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Complex Loci in human and mouse genomes. by Pär G Engström, Harukazu Suzuki, Noriko Ninomiya, Altuna Akalin, Luca Sessa, Giovanni Lavorgna, Alessandro Brozzi, Lucilla Luzi, Sin Lam Tan, Liang Yang, Galih Kunarso, Edwin Lian-Chong Ng, Serge Batalov, Claes Wahlestedt, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Christine Wells, Vladimir B Bajic, Valerio Orlando, James F Reid, Boris Lenhard, Leonard Lipovich

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Inhibition of SOD1 trimerization is a novel drug target for ALS disease by Tae-Gyun Woo, Jin Han, Yuju Kim, Young jun Hwang, Mua Lee, So-mi Kang, Soyoung Park, Yeongseon Ji, Yeon-Ho Chung, Songyoung Baek, Eunbyeol Shin, Minju-Kim, Hyewon Jang, Yun-Jeong Shin, Yonghoon Kwon, Bae-Hoon Kim, Bum-Joon Park

“…About 150 different gene mutations have been reported so far. SOD1 is a well-identified gene associated with ALS. Indeed, SOD1 aggregation has been reported in ALS patients, but the mechanism of SOD1 aggregation remains unclear. …”
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