Implementation of Valid HPV Diagnostics for the Early Detection of Cervical Cancer in Molecular Pathology: HPV 3.5 LCD-Array (Chipron GmbH) vs. PapilloCheck^® (Greiner Bi... by Jan Jeroch, Melanie Winter, Anna Bieber, Agnes Boger, Christina Schmitt, Silvana Ebner, Morva Tahmasbi Rad, Henning Reis, Peter. J. Wild

“…The results of the Vision<i>Array</i>^® test corresponded rather well with the results of the 3.5 LCD-Array.…”
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Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway by Jiawei Zhou, Anqi Cheng, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

“…Methods This study utilized TNBC tissue microarrays to detect Peroxiredoxin 2 (PRDX2) expression levels and analyzed the correlation between PRDX2 and tumor invasion as well as invasion-related gene expression through the TCGA database. …”
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Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer by Fangyuan Jing, Huicheng Jin, Yingying Mao, Yingjun Li, Ye Ding, Chunhong Fan, Kun Chen

“…Long non-coding RNA microarray was applied to investigate the global long non-coding RNA expression profile in colorectal cancer. …”
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Spatial transcriptomics reveal high T cell and monocyte status as predictive and prognostic markers in pancreatic cancer by Yeon Bi Han, Sejoon Lee, Jin-Ok Lee, Se In Jeong, Ki Rim Lee, Soomin Ahn, Kwangrok Jung, Jong-Chan Lee, Yoo-Seok Yoon, Jin-Hyeok Hwang, Ho-Seong Han, Hee Young Na, Jaihwan Kim

“…Conclusions Increased expression of MFAP4 and EGR3 as well as high CD3-, CD4-, and CD8-positive cell infiltration may be predictive markers of the NAT response in PDAC. …”
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Identification of <i>hsa_circ_0018905</i> as a New Potential Biomarker for Multiple Sclerosis by Valeria Lodde, Ignazio Roberto Zarbo, Gabriele Farina, Aurora Masia, Paolo Solla, Ilaria Campesi, Giuseppe Delogu, Maria Rosaria Muroni, Dimitrios Tsitsipatis, Myriam Gorospe, Matteo Floris, Maria Laura Idda

“…Dysregulation of the immune system as well as myelinization-de-myelinization has been shown to correlate with changes in RNA, including non-coding RNAs. …”
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CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints by Hui Li, Hui Zhang, Rujiang Dai, Dian Zheng, Jianghai Zhao, Hong Jing, Xuhui Ma, Lin Zhang, Weihong Sun, Zhimin Suo

“…This study aims to investigate the expression levels, prognostic significance, and clinical implications of CD68, as well as its correlations with six TIICs and four common TICs in DSC.Materials and methodsWe analyzed CD68 mRNA and protein expression using online databases and immunohistochemistry (IHC) on tissue microarray (TMA) sections, comparing DSC tumor tissues with adjacent normal tissues. …”
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Patterns of Human Respiratory Viruses and Lack of MERS-Coronavirus in Patients with Acute Upper Respiratory Tract Infections in Southwestern Province of Saudi Arabia by Ahmed A. Abdulhaq, Vinod Kumar Basode, Anwar M. Hashem, Ahmed S. Alshrari, Nassrin A. Badroon, Ahmed M. Hassan, Tagreed L. Alsubhi, Yahia Solan, Saleh Ejeeli, Esam I. Azhar

“…Nasal swabs were collected from 182 patients and screened for MERS-CoV as well as other respiratory viruses using RT-PCR and multiplex microarray. …”
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Involvement of Urokinase-Type Plasminogen Activator Receptor in the Formation of a Profibrotic Microenvironment in the Epicardial Region by K. V. Dergilev, Z. I. Tsokolayeva, I. B. Beloglazova, Yu. D. Vasilets, D. O. Traktuyev, B. N. Kulbitsky, E. V. Parfenova

“…We used histological and immunofluorescent staining, microarray analysis of proinflammatory cytokine levels, and a method for assessing the migratory properties of epicardial cells.Results. …”
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Multi-omics integration reveals functional signatures of gut microbiome in atherosclerosis by Hongbo Shi, Meitao Wu, Xiaoliang Wu, Zhuoxin Liu, Shuo Jiang, Gen Li, Yetong Yang, Yanghe Fu, Qiuping Wang, Guangde Zhang, Liang Cheng

“…While the associations between microbial imbalance and AS pathogenesis are well-documented, the pathophysiological mechanisms governing microbe-host crosstalk remain incompletely characterized. …”
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The significance of long chain non-coding RNA signature genes in the diagnosis and management of sepsis patients, and the development of a prediction model by Yong Bai, Jing Gao, Yuwen Yan, Xu Zhao

“…WGCNA analysis excluded outlier samples, leaving 2,029 genes for relationship analysis between sepsis- and non-sepsis patient-associated LncRNA network representation modules, as well as Wein plots of differential genes versus genes in key modules of weighted co-expression network analysis to analyze gene intersections. …”
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Improvement of bone regeneration by a synergistic combination of octacalcium phosphate and water glass by Won-Pyo Lee, Euisin Yang, Woong Kim, Riessa Nanda Mertamani, Hana Lee, Se Eun Kim, Kyung Mi Shim, Seong Soo Kang, Sukyoung Kim, Seok-Jun Kim, Jooseong Kim

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Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia. by Brady Tang, Tricia Thornton-Wells, Kathleen D Askland

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Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis by Fanjie Lin, Ken Lin, Donglei Li, Weiguo Kong, Jiayu Zhuang, Wei He, Xinguang Wei, Tianchi Xiao, Hao Zu, Zili Zhang, Wenju Lu

“…Eventually, ST6GAL1 was selected as the core gene and its localization in the plasma cells as well as its over-expression in the lungs of bleomycin-injured mice was experimentally validated. …”
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Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression by Fangjian Shang, Hongfeng Nie, Liyan Du, Jin Shang, Xiangquan Song, Ya Chen, Hui Li, Zhuo Wang, Yixin Qi, Liyan Zhao

“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer by Yongchang Zheng, Yue Shi, Si Yu, Yuanyuan Han, Kai Kang, Haifeng Xu, Huajian Gu, Xinting Sang, Yang Chen, Jingyu Wang

“…GTSE1 is well correlated with tumor progression; however, little is known regarding its role in liver cancer prognosis. …”
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Exploring miR-30b Methylation and MALAT-1 Expression as Diagnostic Biomarkers for Non-Small Cell Lung Cancer by Marziyeh Memarzadeh, Habib Zarredar, Milad Asadi, Armin Sadeghi, Venus Zafari, Shahryar Hashemzadeh, Hamed Sabbagh-Jadid, Mortaza Raeisi

“…This study aimed to investigate miR-30b DNA methylation and metastasis associated lung adenocarcinoma transcript 1 (MALAT-1) expression patterns as potential diagnostic biomarkers for non-small cell lung cancer (NSCLC).Method: In this cross-sectional study, miR-30b DNA methylation and MALAT-1 expression patterns were first explored using microarray data retrieved from the NSCLC dataset in the Cancer Genome Atlas (TCGA)-LUNG. …”
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Identifying 4 Novel lncRNAs as Potential Biomarkers for Acute Rejection and Graft Loss of Renal Allograft by Zedan Zhang, Yanlin Tang, Hongkai Zhuang, Enyu Lin, Lu Xie, Xiaoqiang Feng, Jiayi Zeng, Yanjun Liu, Jiumin Liu, Yuming Yu

“…The internal testing set verified the result well. Gene set enrichment analysis which expounded NOD-like receptor, the Toll-like receptor signaling pathways, and other else playing important role in immune response was enriched by the 4 lncRNAs. …”
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Multiple myeloma with extramedullary plasmacytoma: pathogenesis and clinical case by M. V. Firsova, N. V. Risinskaya, M. V. Solovev, T. N. Obukhova, M. A. Kislitsyna, E. E. Nikulina, I. A. Yakutik, T. V. Abramova, A. B. Sudarikov, A. M. Kovrigina, L. P. Mendeleeva

“…The review presents literature data on the pathogenesis of extramedullary disease, as well as a clinical example of a comprehensive study of the tumor substrate.Aim. …”
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A 22 month prospective assessment of neutralizing and IgG antibody levels against SARS-CoV-2 variants following homologous and heterologous BNT162b2 boosting by Aini Syahida Mat Yassim, Anis Atifah Mohd Hisham, Nik Nur Atiqah Nik Daud, Nur Diana Anuar, Ti-Myen Tan, Rapeah Suppian, Mat Jusoh Siti Asmaa, Amiratul Aifa Mohamad Asri, Maryam Azlan, Nur Suhaila Idris, Rosediani Muhamad, Mohd Nor Norazmi

“…Using the ImmuSAFE™ COVID + microarray, we evaluated IgG-S and NAb against Wuhan-Hu and VoCs (Alpha, Beta, Delta, Omicron), as well as IgG-N responses to Wuhan-Hu. …”
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ASSOCIATION OF THE COMBINATION OF STEMNESS GENE AMPLIFICATIONS AND COPY NUMBER ABERRATIONS OF WNT-SIGNALING GENES IN BREAST TUMORS WITH METASTASIS by N. V. Litviakov, M. K. Ibragimova, M. M. Tsyganov, I. V. Deriusheva, A. M. Pevsner, E. Yu. Garbukov, A. V. Doroshenko, E. M. Slonimskaya

“…We studied the association between the presence of 2 or more stemness gene amplifications as well as copy number aberrations (CNAs) of WNT signaling genes in residual breast tumor and metastasis. …”
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