Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation by Olof Gidlöf, Andrea L. Johnstone, Kerstin Bader, Bohdan B. Khomtchouk, Jiaqi J. O'Reilly, Selvi Celik, Derek J. Van Booven, Claes Wahlestedt, Bernhard Metzler, David Erlinge

“…Knockdown of the major H3K9 methyltransferase G9a resulted in a significant decrease in H3K9me2 levels across Mtor, increased Mtor expression, as well as decreased autophagic activity in response to rapamycin and serum starvation. …”
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The potential of MCM8 as a biomarker in esophageal carcinoma: a comprehensive analysis integrating m6a methylation and angiogenesis by Xu-Sheng Liu, Yong Xu, Li-Song Dai, Ao Li, Jie Liu, Yu Zhang, Jin Xie, Zhi-Jun Pei

“…MCM8 expression in ESCA tissues was evaluated by immunohistochemical staining on a tissue microarray. Pearson correlation analysis identified co-expressed genes, followed by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses. …”
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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis by S. M. Nuruzzaman Nobel, S M Masfequier Rahman Swapno, Md. Ashraful Hossain, Mejdl Safran, Sultan Alfarhood, Md. Mohsin Kabir, M. F. Mridha

“…The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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MCM6 rs4988235 Allele G, AGT rs699 Allele C, ACE rs4343 Allele A, FADS1 rs174547 Allele C, DCHR7 rs12785878 Allele G, and GC rs7041 Allele T: Candidate Genes for Preeclampsia Preve... by Deviana Soraya Riu, Isharyah Sunarno, Efendi Lukas

“…The nutrigenomic test was performed using DNA microarray method to examine variant genes associated with food response and nutrient metabolites. …”
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Molecular profiles of tumor contrast enhancement: A radiogenomic analysis in anaplastic gliomas by Xing Liu, Yiming Li, Zhiyan Sun, Shaowu Li, Kai Wang, Xing Fan, Yuqing Liu, Lei Wang, Yinyan Wang, Tao Jiang

“…However, the biological behaviors and molecular mechanism of enhanced tumor are not well illustrated. The aim of this study was to investigate the molecular profiles associated with anaplastic gliomas (AGs) presenting CE on postcontrast T1‐weighted MR imaging. …”
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Functional characteristics of fresh antitumor immune interferer GDF-15 in multiple cancers by Min Fang, Ziyu Wang, Yuxin Zhou, Fengrui Yang, Zhu Wu, Jian Xiao

“…The correlations between GDF-15 expression and immune cell infiltration, immune-related genes, as well as immune checkpoints were also under investigation. …”
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Discovery of novel molecular characteristics and cellular biological properties in ameloblastoma by Sayuri Kondo, Akinobu Ota, Takayuki Ono, Sivasundaram Karnan, Md Wahiduzzaman, Toshinori Hyodo, Md Lutfur Rahman, Kunihiro Ito, Akifumi Furuhashi, Tomio Hayashi, Hiroyuki Konishi, Shinobu Tsuzuki, Yoshitaka Hosokawa, Yoshiaki Kazaoka

“…Our comparative cDNA microarray analysis and gene set enrichment analysis (GSEA) showed that ameloblastoma exhibited a distinct gene expression pattern from the normal tissues: KRAS‐responsive gene set is significantly activated in ameloblastoma. …”
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Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation by Jesper Karlsson, Lina Wirestam, Hanna Duàn, Suhana Ahmad, Daniel Appelgren, Helena Enocsson, Jonas Wetterö, Christopher Sjöwall

“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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Bayesian inference towards the resolution of molecular evolution: application to the “Trichoderma harzianum sensu lato” clade by Druzhinina I S, Kubicek C P

“…The clade containing the ex-neotype strain of T. harzianum included exclusively clonally propagating isolates from temperate climates, and was clearly distinguished from all other “H. lixii/T. harzianum” lineages by multivariate analysis of phenotype microarray data. We propose that only this lineage should be regarded as T. harzianum sensu stricto, and that the other lineages be regarded as T. harzianum sensu lato until phenetic characters have been defined which allow their description as separate taxa.…”
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Oxidative Nanopatterning of Titanium Surface Influences mRNA and MicroRNA Expression in Human Alveolar Bone Osteoblastic Cells by Maidy Rehder Wimmers Ferreira, Roger Rodrigo Fernandes, Amanda Freire Assis, Janaína A. Dernowsek, Geraldo A. Passos, Fabio Variola, Karina Fittipaldi Bombonato-Prado

“…Titanium implants have been extensively used in orthopedic and dental applications. It is well known that micro- and nanoscale surface features of biomaterials affect cellular events that control implant-host tissue interactions. …”
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Effects of long-term pioglitazone treatment on peripheral and central markers of aging. by Eric M Blalock, Jeremiah T Phelps, Tristano Pancani, James L Searcy, Katie L Anderson, John C Gant, Jelena Popovic, Margarita G Avdiushko, Don A Cohen, Kuey-Chu Chen, Nada M Porter, Olivier Thibault

“…Interestingly, long-term treatment of mouse models of Alzheimer's disease (AD) with TZDs also has been shown to reduce several well-established brain biomarkers of AD including inflammation, oxidative stress and Abeta accumulation. …”
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Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer by Haihang Nie, Shilin Fang, Rui Zhou, Yifan Jia, Jingkai Zhou, Yumei Ning, Yali Yu, Yuntian Hong, Fei Xu, Qiu Zhao, Jiayan Nie, Fan Wang

“…Methods RIG‐I expression was measured in CRC and normal samples based on analysis of the public databases, a tissue microarray, and CRC cell lines. The correlation between RIG‐I and immune microenvironment was explored using well‐established biological algorithms and in vitro and in vivo experiments. …”
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Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas by Rebecca Schüle, Christine Dictus, Benito Campos, Feng Wan, Jörg Felsberg, Rezvan Ahmadi, Franz-Simon Centner, Niels Grabe, Guido Reifenberger, Justo L. Bermejo, Andreas Unterberg, Christel Herold-Mende

“…Furthermore, we assessed the prognostic relevance of β-catenin expression in a tissue microarray comprising 283 astrocytomas. Expression of β-catenin, its transcriptional cofactors TCF-1 and TCF-4 as well as GSK-3β and APC, constituents of the β-catenin degradation complex was confirmed by RT-PCR in all cultures. …”
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HIF-2α not HIF-1α overexpression confers poor prognosis in non–small cell lung cancer by Zhao-Jia Gao, Yong Wang, Wei-dong Yuan, Jun-qiang Yuan, Kai Yuan

“…In present study, immunohistologic expression of HIF-1α/ HIF-2α was studied in a tissue microarray of 140 Stage I-III NSCLCs and correlated with clinicopathologic parameters and clinical outcome. …”
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Bioinformatics analysis identifies WNK1 gene as a potential biomarker for cholangiocarcinoma diagnosis and immune infiltration by Qi Sun, Xianli Lei, Xiangrong Meng, Caijun Zha, Lei Yan, Wenjing Zhang

“…However, the relationship between WNK1 and CHOL development, as well as the potential mechanisms involved, remains poorly understood. …”
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USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway by Ni Xiong, Yue Wang, Junhong Jiang

“…Validation was conducted using tissue microarray (TMA) analysis and immunohistochemistry (IHC) to compare USP5 expression levels in HNSCC tissues versus adjacent normal tissues. …”
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Study on hsa_circ_101209 in Plasma of Pregnant Women with Deep Venous Thrombosis by Zhang Y, Li J

“…Sixty women with DVT were selected as the DVT group, and 60 women without DVT as the non-DVT group. hsa_circ_14797 in plasma was detected, as well as D-dimer (D-D) concentration and P-selectin expression. …”
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Disulfidptosis-related gene in acute myocardial infarction and its diagnostic value and functions based on bioinformatics analysis and machine learning by Liwen Chen, Jinru Wei, Jinru Wei, Guoxiong Deng, Guoxiong Deng, Guien Xu

“…At the same time, key genes further screened by Support Vector Machine (SVM), Lasso regression, as well as random forest. By intersecting the results of the three, we ended up with hub genes for AMI. …”
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Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study by Leah Trumet, Leah Trumet, Bettina Grötsch, Abbas Agaimy, Kerstin Galler, Carol Geppert, Linus Winter, Linus Winter, Jutta Ries, Jutta Ries, Marco Kesting, Marco Kesting, Manuel Weber, Manuel Weber

“…A better understanding of similarities and differences of the diseases could eventually also pave the way for the use of immunotherapy in non-malignant diseases.MethodsIn the current pilot study, a tissue microarray (TMA) was created of a total of 29 patients with periodontitis (PD, n=4), oral Leukoplakia (OL, n=4), oral Lichen Planus (OLP, n=4), oral squamous cell cancer without lymphatic metastases (OSCC N0, n=5), or with lymphatic metastases (OSCC N+, n=4), OSCC biopsies prior to and resection specimens after anti-PD1 immunotherapy (IT) (each n=3) as well as healthy control gingiva (n=5). …”
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PLK3 facilitates replication of swine influenza virus by phosphorylating viral NP protein by Caiyue Ren, Tong Chen, Shishuo Zhang, Qingxia Gao, Jiahui Zou, Peng Li, Biaoxiong Wang, Yaxin Zhao, Aotian OuYang, Sizhu Suolang, Hongbo Zhou

“…PLK3 is a member of the PLK family, which is a highly conserved serine/threonine kinase in eukaryotes and well known for its role in the regulation of cell cycle and cell division. …”
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