A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

“…This study is aimed at identifying whether circRNAs could be used as the diagnostic biomarkers for NSCLC. Methods. The heterogeneity of samples in this study was assessed by principal component analysis (PCA). …”
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Application of collateral-dredging tendon-strengthening exercise in postoperative rehabilitation of patients undergoing spinal surgery (通络强筋护脊操在脊柱手术患者术后康复中的应用效果观察)... by ZHU Fengxiang (朱凤祥), HUANG Xiaoling (黄小玲), ZHU Hongying (朱洪英)

“…Objective To investigate the effect of collateral-dredging tendon-strengthening exercise on postoperative rehabilitation of patients undergoing spinal surgery. Methods A convenience sample of 140 patients undergoing spinal surgery under general anesthesia were included as research objects. …”
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Global, regional, and national liver cancer attributable to smoking and alcohol use burden, 1990–2021: analysis for the global burden of disease 2021 study by Chenyi Liu, Taiting Shi, Shu Li, Shiwen Wu, Jiawen Chen, Chao Cai, Mingqin Lu

“…Smoking and alcohol consumption are major risk factors for liver cancer. Methods We analyzed data from the Global Burden of Disease (GBD) Study 2021. …”
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Artificial intelligence in Anatomy: Potential uses and challenges by Lubna Faisal

“…For this new innovative technologies and teaching methods should be incorporated for both learning and assessment of anatomy [2]. …”
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Clinical efficacy and quality of life in elderly patients with lumbar degenerative disease treated with TLIF combined with unilateral pedicle screw fixation: a randomized controlle... by Cheng-Peng Li, Kai-Kai Feng, Xiao-Bing Xiang, Kai-Yin Gao, Wei-Wei Zhang, Zhen-Yu Nie, Dong Zhao, Wen-Xin Liao, Guang-Ru Cao

“…Pain and functional status were preoperatively evaluated, in addition to being postoperatively evaluated at 1, 6, and 12 months, using the visual analogue scale (VAS), Oswestry Disability Index (ODI), Japanese Orthopaedic Association (JOA) score, and Short Form-36 (SF-36) health survey questionnaire. …”
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Multi-Focus Image Fusion Based on Dual-Channel Rybak Neural Network and Consistency Verification in NSCT Domain by Ming Lv, Sensen Song, Zhenhong Jia, Liangliang Li, Hongbing Ma

“…In multi-focus image fusion, accurately detecting and extracting focused regions remains a key challenge. Some existing methods suffer from misjudgment of focus areas, resulting in incorrect focus information or the unintended retention of blurred regions in the fused image. …”
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Squalomix: shark and ray genome analysis consortium and its data sharing platform [version 2; peer review: 2 approved] by John Rozewicki, Kazuaki Yamaguchi, Osamu Nishimura, Ryo Misawa, Takashi Asahida, Mitsumasa Koyanagi, Akihisa Terakita, Filipe Castro, André Machado, Milton Tan, Salvatore D'Aniello, Shotaro Hirase, Akane Kawaguchi, Chiharu Tanegashima, Akinori Teramura, Masaru Yagura, Taiki Niwa, Kaori Tatsumi, Yuta Ohishi, Susumu Hyodo, Mitsutaka Kadota, Itsuki Kiyatake, Keiichi Sato, Kazuyuki Yamada, Kiyonori Nishida, Yasuko Semba, Shinya Yamauchi, Sho Tanaka, Tatsuya Sakamoto, Norio Miyamoto, Atsushi Toyoda, Rui Matsumoto, Iker Irisarri, Atsuko Yamaguchi, Tazro Ohta, Kiyomi Murakumo, Junna Kawasaki, Masayuki Horie, Yoshinobu Uno, Shigehiro Kuraku

“…Their peculiar body fluid composition has also hindered the establishment of methods to perform routine cell culturing required for their karyotyping. …”
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Exploring the co‐morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model by Mingfeng Li, Xinghan Wu, Lin Jiang, Min Liu, Gong Yanju, Xiaomeng Li, Fan Tian, Fan Ye, Jinlong Wang, Siyuan Wang, Chuan Qin, Ling Zhang

“…However, the precise mechanism by which AD antagonizes lung cancer progression warrants further elucidation. Methods To this end, we established a co‐morbidity model using 5xFAD transgenic mice induced with the carcinogen urethane. …”
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脑静脉窦血栓形成患者动态脑血流自动调节受损：基于TCD和默读刺激的评估 Impaired Dynamic Cerebral Autoregulation in Patients with Cerebral Venous Sinus Thrombosis: Evaluation Using Transcranial Doppler and Silent Re... by 陈松伟1，2，3*，陈虹秀1，2，3*，段建钢4，崔柳平1，2，3，刘然1，2，3，邢英琦1，2，3（*第一作者） (CHEN Songwei1,2,3*, CHEN Hongxiu1,2,3*, DUAN Jiangang4, CUI Liuping1,2,3, LIU Ran1,2,3, XING Yingqi1,2,3 (*contributed equally) )

“…Patients with larger involvement range had lower NVC reactivity to visual stimulation than those with smaller involvement range.…”
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Comparative evaluation of three polymerase chain reaction primer sets for accurate molecular detection of Trypanosoma lewisi in wild rodents in Indonesia by Aditya Yudhana, Gusti Ayu Illiyin Putri Santosa, April Hari Wardhana, Frenky Laksana Putra, Ryanka Edila, Dyah Haryuningtyas Sawitri, Ratih Novita Praja, Muhammad Aqil Kurnianto, Aldi Gusnizar Rizaldy Tanjung, Marc Desquesnes, Makoto Matsubayashi

“…DNA amplification products were visualized using agarose gel electrophoresis. Diagnostic performance was evaluated based on sensitivity and specificity calculations using microscopy as the reference standard. …”
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“Koshimagari Exercise” for Adult Spinal Deformity in Older Adults: Assessment of Home-Based Exercise Outcomes in a Prospective Multicenter Study by Hidetomi Terai, Shinji Takahashi, Masatoshi Hoshino, Hiroshi Taniwaki, Koji Tamai, Toshimitsu Ohmine, Tamotsu Nakatsuchi, Goya Shinbashi, Masatoshi Teraguchi, Masakazu Minetama, Kei Watanabe, Naritoshi Sato, Takuya Kitamura, Masaru Kanda, Tadao Tsujio, Yuichi Takeuchi, Tatsuki Mizouchi, Katsuhito Ishizu, Toshihito Ebina, Yasunari Muraoka, Tomonori Sodeyama, Hiroshi Mikami, Yuji Kasukawa, Takahiko Hyakumachi, Kazuhiro Ishida, Kazufumi Miyagishima, Yosuke Oishi, Kiyonori Yo, Ryota Kimura, Hiromichi Sato, Keiji Nagata, Yu Yamato, Ko Matsudaira, Naohisa Miyakoshi, Yukihiro Matsuyama, Hirotaka Haro, Hiroshi Hashizume, Hiroshi Yamada, Takashi Kaito, Project Committee of the Japanese Society for Spine Surgery and Related Research (JSSR)

“…Clinical evaluations were conducted using the Oswestry Disability Index (ODI), five-level classification system of EuroQol-5 Dimensions (EQ-5D), Japanese edition of Scoliosis Research Society-22r (SRS-22r), and visual analog scale (VAS) for LBP at baseline and 3, 6, and 12 months. …”
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Platelet-rich plasma therapy for knee osteoarthritis: Insights from real-world clinical data in Japan by Yoshitomo Saita, Yohei Kobayashi, Sayuri Uchino, Hirofumi Nishio, Takanori Wakayama, Shin Fukusato, Yasumasa Momoi, Ryosuke Nakajima, Nanako Yamamoto, Shinnosuke Hada, Haruka Kaneko, Muneaki Ishijima

“…The eligibility criteria included chronic knee pain unresponsive to conservative treatment for KOA. Visual Analog Scale (VAS) for knee pain were collected at baseline and 3 and 6 months post-treatment. …”
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White matter hyperintensity tissue property spatial variations as a function of cognitive status in Parkinson’s disease by Mariyemuguli Reheman, Sagar Buch, Naying He, Pei Huang, Qiurong Yu, Xinhui Wang, Yu Liu, Youmin Zhang, Zhijia Jin, Yan Li, Peng Liu, Shengdi Chen, E. Mark Haacke, Fuhua Yan

“…Water content, T1, and T2* measures were derived from qMRI data and tissue property heatmaps and periventricular distance profiles were constructed for all groups to visualize location-dependent tissue alterations of WMH relative to the lateral ventricles. …”
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Mir-218-5p from Extracellular Vesicles of Endometrium in Patients with Recurrent Implantation Failure Impairs Pre-Implantation Embryo Development by Cai L, Lv M, Wei J, Liu C, Li Y, Liao Z, Li T, Zhang H, Xi L, Sui C

“…The abnormal segregation genes of trophectoderm (TE) and inner cell mass (ICM) were visualized via qRT-PCR and immunofluorescence staining. …”
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A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy by Robert Hodgson, Matthew Walton, Helen Fulbright, Laura Bojke, Ruth Walker, Alexis Llewellyn, Sofia Dias, Lesley Stewart, David Steel, John Lawrenson, Tunde Peto, Mark Simmonds

“…Results of these studies suggest that anti-vascular endothelial growth factor treatments offer some additional benefits in terms of preserved visual acuity but also incur substantial additional costs relative to pan-retinal photocoagulation. …”
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Effectiveness of Chemical Management for Broadleaf Weeds in Autumn-Sown Chickpea (Cicer arietinum L.) by Mozhgan Veisi, Mehdi Minbashi Moeini, Sepideh Hatami, Mohammad Saleh Mansouri

“…Sophia, Alyssum spp. and total weeds. In the visual evaluation, the highest efficiency belonged to aclonifen at 4 l.ha-1, followed by PRE aclonifen at 2 and 3 l. ha-1, flumioxazin and oxyfluorfen + aclonifen. …”
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Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis by Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John G Lawrenson, Tunde Peto, David Steel

“…Overall, anti-vascular endothelial growth factor was slightly better than panretinal photocoagulation at preventing vision loss, measured as best corrected visual acuity, at up to 2 years follow-up [mean difference in the logarithm of the minimum angle of resolution −0.089 (or 3.6 Early Treatment Diabetic Retinopathy Study letters), 95% confidence interval −0.180 to −0.019]. …”
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Transcorneal electrical stimulation restores DNA methylation changes in retinal degeneration by Ben Yi Tew, Gerald C. Gooden, Pei-An Lo, Pei-An Lo, Dimitrios Pollalis, Dimitrios Pollalis, Brandon Ebright, Brandon Ebright, Alex J. Kalfa, Alejandra Gonzalez-Calle, Alejandra Gonzalez-Calle, Biju Thomas, Biju Thomas, David N. Buckley, Thomas Simon, Zeyi Yang, Ege Iseri, Ege Iseri, Cody L. Dunton, Vadim Backman, Stan Louie, Stan Louie, Gianluca Lazzi, Gianluca Lazzi, Gianluca Lazzi, Mark S. Humayun, Mark S. Humayun, Bodour Salhia

“…With promising results, there is a need for detailed molecular characterization of the therapeutic effects of TES.MethodsControlled, non-invasive TES was delivered using a custom contact lens electrode to the retinas of Royal College of Surgeons (RCS) rats, a model of retinal degeneration. …”
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Synergistic effects of 1-MCP and H₂S co-treatment on sugar and energy metabolisms in postharvest strawberry fruit by Xingyue Wang, Xingyue Wang, Tian Qiu, JingJing Jiang, Kaili Shi, Zhikang Liu, Zhikang Liu, YanYan Wang, Qingyuan Song, Chen Zhang, Tingyu Wu, Dan Chen, Xiaohui Yang, Fang Liu, Qing Gong, Wei Lan, Li Wang

“…However, little knowledge was available for the effect of the combined treatment of 1-MCP and H2S on the quality maintenance of postharvest strawberry fruit.MethodsThe synergistic effects of 1.0 μL L−1 1-MCP and 0.8 mmol L−1 sodium hydrosulfide (NaHS, H2S donor) combined treatment on the sugar and energy metabolisms of strawberry fruit during cold storage at 4 ± 0.5°C with a relative humidity of 80–85% for 15 d were studied.ResultsThe results showed that the combined treatment effectively suppressed the increase of decay rate, decay index, and weight loss rate while maintaining the firmness and visual quality of strawberry fruit compared to the 1-MCP or H2S treatment. …”
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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated with unfavorable 90‐day functional outcomes despite successful reperfusion. …”
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