ENABLE—App-Based Digital Capture and Intervention of Patient-Reported Quality of Life, Adverse Events, and Treatment Satisfaction in Breast Cancer: Protocol for a Randomized Contro... by Thomas M Deutsch, Léa L Volmer, Manuel Feisst, Laura Bodenbeck, Kathrin Hassdenteufel, Lara Tretschock, Christiane Breit, Stefan Stefanovic, Armin Bauer, Carolin Anders, Lina Weinert, Tobias Engler, Andreas D Hartkopf, Nico Pfeifer, Pascal Escher, Marc Mausch, Oliver Heinze, Marc Suetterlin, Sara Y Brucker, Andreas Schneeweiss, Markus Wallwiener

“…In the intervention group, HRQoL was also assessed briefly every week using a visual analog scale (EQ-VAS). In cases of significant deterioration, therapy-associated side effects were assessed in a graduated manner, recommendations were sent to the patient, and the treatment team was informed. …”
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Effect of Floating Needle Perfusion Therapy combined with Joint Mobilization on Shoulder Pain of Hemiplegia after Stroke by Xin WANG, Hu LI, Xiuyan LU

“…Objective:To observe the effect of floating needle perfusion therapy combined with joint mobilization on shoulder pain of hemiplegia after stroke. Methods: A total of 90 hemiplegia patients with shoulder pain after stroke in the department of rehabilitation medicine of Shandong Provincial Third Hospital from February to December 2019, which were divided into the control group, the floating needle group and the comprehensive group according to the random number table, with 30 cases in each group. …”
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The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial by Sewar Khatib, Yuval Palgi, Yoni K Ashar, Natalya Polyvyannaya, Pavel Goldstein

“…Pain intensity levels (per a Visual Analog Scale), blood pressure, heart rate, blood oxygen saturation, and hand grip strength (using a Jamar hand dynamometer) were measured before and after each of the 4 weekly therapeutic sessions. …”
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Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors by Yi Duan, Wen Chen, Jian Xu, Xiaoyu Zhang, Xiaozhen Zhang, Tingbo Liang, Xueli Bai, Mengyi Lao, Hanshen Yang, Muchun Li, Honggang Ying, Lihong He, Kang Sun, Chengxiang Guo, Haitao Jiang

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Influence of the duration of psoriatic arthritis on the achievement of remission and minimal disease activity during therapy with genetically engineered biologic drugs. Data from t... by E. Yu. Loginova, T. V. Korotaeva, E. E. Gubar, Yu. L. Korsakova, M. V. Sedunova, I. N. Pristavskiy, I. N. Kushnir, I. F. Umnova, S. S. Kudishina, E. L. Nasonov

“…To study the frequency and timing of the onset of remission and minimal disease activity after the administration of genetically engineered biologic drugs (GEBD) in patients with early and long-term psoriatic arthritis observed within the framework of the All-Russian register of patients with psoriatic arthritis.Material and methods. The study included 140 patients with psoriatic arthritis (77 men, 63 women) who met the CASPAR criteria, who took part in the All-Russian register and were followed up every 6 months. …”
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ARCHITECTONICS OF THE SILENCE IN VERCORS’ NOVEL “THE SILENCE OF THE SEA” by Tatyana A. Pakhareva

“…The combination of the structural-semiotic, contextual, and holistic methods during the story analysis allowed us to come to the conclusion that compositionally the “silence of the sea”, which corresponds to the “surface/depth” structure, is implemented in Vercors’ story in a similar way to L. …”
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Impact of Posterior Quadratus Lumborum Block on Acute Pain Relief and Chronic Pain Prevention in Breast Cancer Surgery by Min Wang, Shu-Jie Niu, Jin Wu, Yi-Wei Zhong, Zi-Yun Lu, Qun Fu, Bing-Bing Li

“…The primary outcome was the visual analog scale (VAS) pain scores recorded at 2, 6, 18, 24, and 48 h post-surgery under rest and motion conditions. …”
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Effectiveness of Digital Health Interventions for Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis by Miaoqing Zhuang, Intan Idiana Hassan, Wan Muhamad Amir W Ahmad, Azidah Abdul Kadir, Xiaodong Liu, Furong Li, Yinuo Gao, Yang Guan, Shuting Song

“…ObjectiveThis systematic review and meta-analysis assesses the clinical effectiveness of smartphone apps, wearable monitors, and web-delivered platforms in four COPD management areas: (1) quality of life (measured by the COPD Assessment Test [CAT] and St George’s Respiratory Questionnaire), (2) self-efficacy (assessed by the General Self-Efficacy Scale), (3) functional capacity (evaluated via the 6-minute walk test and Modified Medical Research Council Dyspnea Scale), and (4) health care use (indicated by hospital and emergency department visits). MethodsA systematic review was conducted using predefined search terms in PubMed, Embase, Cochrane, and Web of Science up to January 26, 2025, to identify randomized trials on digital health interventions for COPD. …”
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Effect of Repetitive Transcranial Magnetic Stimulation on Patients with Post-Stroke Cognitive Impairment by Zheyi YU, Weiming ZHANG

“…Before and after treatment, the cognitive function scores of the two groups were compared, the changes of mini-mental state examination (MMSE) and Montreal cognitive function (MoCA) scores were compared, the activities of daily living (ADL) and auditory verbal learning test (AVLT) were observed. ELISA method was used to observe the changes of brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), interleukin-6(IL-6) and high-sensitivity C-reactive protein (hs-CRP) in the two groups after treatment.Results:There were no significant differences in the scores of MoCA, including orientation (ORT), visual space and executive function (EF), naming (NAM), memory (MEM), attention (ATT), language (LANG) and abstract ability (ABS) before treatment between the two groups (<italic>P</italic>&gt; 0.05). …”
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Evaluation of clinical efficacy of pelvic ultrasound monitoring combined with scale scoring in the treatment of interstitial cystitis by intravesical instillation regimen combined... by Lin Liu, Liang Xue, Jiahe Zhou, Bingzheng Dong, Yang Li, Zhigang Li, Yang Dong, Conghui Han

“…This study aimed to evaluate the clinical efficacy of a treatment regimen combining intravesical instillation of heparin and alkalized lidocaine, hydrodistention, and transurethral fulguration, using pelvic ultrasound monitoring and symptom scales to assess patient outcomes. Methods From June 2016 to June 2023, patients who were diagnosed as interstitial cystitis in urology department of the xuzhou central hospital were selected. …”
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Clinical Outcomes Comparison of Combined Small Incision Lenticule Extraction with Collagen Cross-Linking Versus Small Incision Lenticule Extraction Only by Ayoub Chabib, Massimo Mammone, Chiara Fantozzi, Rebecca R. Lian, Natalie A. Afshari, Michael H. Goldbaum, Marco Fantozzi

“…Retrospective comparative case series. Methods. The study comprised 70 eyes (35 patients); 40 eyes were corrected using SMILE and 30 eyes were corrected using SMILE Xtra using a low energy protocol. …”
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Scapular dyskinesis-based exercise therapy versus multimodal physical therapy for subacromial impingement syndrome in young overhead athletes with scapular dyskinesis: a randomized... by Meilin Wen, Xuanming Hu, Guiying Bao

“…Abstract Objective To compare the efficacy and underlying mechanisms of scapular dyskinesis-based exercise therapy (SDBET) and multimodal physical therapy (MPT) in young male overhead athletes with subacromial impingement syndrome (SIS) and scapular dyskinesis (SD). Methods This single-center, single-blind, parallel-group superiority randomized controlled trial was designed to compare two interventions in athletes clinically diagnosed with SIS and SD. …”
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Investigating Protective and Risk Factors and Predictive Insights for Aboriginal Perinatal Mental Health: Explainable Artificial Intelligence Approach by Guanjin Wang, Hachem Bennamoun, Wai Hang Kwok, Jenny Paola Ortega Quimbayo, Bridgette Kelly, Trish Ratajczak, Rhonda Marriott, Roz Walker, Jayne Kotz

“…At the individual level, where responses are highly personal, these XAI techniques provided case-specific insights through visual representations, distinguishing between protective and risk factors and illustrating their impact on predictions. …”
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Effect of ketorolac tromethamine on pain management in patients with condyloma acuminata treated with 5-aminolevulinic acid photodynamic therapy by Xiaomeng Chen, Chang Liu, Shuanglin Cao, Xin Wang

“…Combining ketorolac tromethamine with the two-step irradiation method can further reduce pain generated in the initial stage of ALA-PDT and improve patient satisfaction with the treatment.…”
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Use of first metatarsophalangeal joint chondroplasty with the autologous matrix-induced chondrogenesis technique for the treatment of patients with hallux rigidus: immediate result... by M. R. Nurmukhametov, M. A. Makarov, E. I. Byalik, V. E. Byalik, V. A. Nesterenko

“…To date, there is no single approach to choosing a method of surgical treatment of hallux rigidus. The autologous matrix-induced chondrogenesis (AMIC) technique is known to be quite successfully used for the treatment of osteochondral defects in the knee, hip, and ankle joints.Objective: to study the immediate results of first MTPJ chondroplasty using the AMIC technique in patients with hallux rigidus.Subjects and methods. …”
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Virtual reality-assisted rehabilitation for postoperative C5 palsy: a pilot exploratory randomized controlled trial by Kyung-Soo Suk, Jinyoung Park, Taeyeon Choi, Byung Ho Lee, Yongjin Ahn, Sunung Yun, Si Young Park, Hak Sun Kim, Seoung-Hwan Moon, Ji-Won Kwon

“…However, its application in postoperative C5 palsy rehabilitation remains underexplored. Methods This single-center randomized controlled trial was conducted from January to December 2023 at a tertiary academic hospital. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…As these fields converge, musculoskeletal diagnostics methods are poised to evolve into a more precise, personalized, and patient-centered discipline, driving meaningful improvements in musculoskeletal health worldwide.…”
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Development and validation of a nomogram for predicting low bone mineral density in male patients with ankylosing spondylitis by Xiaotong Yang, Qin Cheng, Yifan Li, Hao Tang, Hao Tang, Xin Chen, Lijun Ma, Jing Gao, Wei Ji

“…Based on the regression coefficients, we developed visualized nomogram prediction models for LS and LH low BMD, accompanied by an interactive online prediction tool. …”
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Pathogen Distribution, Drug Resistance, and Postoperative High-Quality Nursing Intervention Effectiveness in Knee Osteoarthritis Patients After Knee Arthroplasty With Postoperative... by Tang Y, Fu B, Tong Q

“…Drug susceptibility testing was performed using the K-B disk diffusion method. Additionally, venous blood samples were collected from both the infection and control groups one week after surgery, and serum levels of inflammatory markers [interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), procalcitonin (PCT)] were measured using enzyme-linked immunosorbent assay (ELISA). …”
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Clinical and radiographical analysis of percutaneous kyphoplasty with multi-point cement anchoring technique for preventing bone cement displacement in Kümmell’s disease of stage I... by Heng Wu, Xiao Dai, Hao Liu, Xiang Yang, Shenao Liu, Shuang Xu, Hao Chi, Yuquan Chen, Song Wang

“…BackgroundThe present study introduced a novel technique called percutaneous kyphoplasty with multi-point cement anchoring technique (A-PKP) to prevent bone cement displacement in patients with stage I and II Kümmell’s disease (KD).MethodsA total of 82 patients with stage I and II KD were treated with PKP in our hospital from April 2020 to October 2022. …”
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