Network pharmacology and experimental study of Angelica sinensis and Astragalus membranaceus capsules in treating heart failure by Xue Wu, Ai Liu, Xinfang Lv, Xiaodong Zhi, Xiangting Zeng, Kai Liu, Xinke Zhao, Bing Jiang, HuGang Jiang, Yingdong Li

“…Objective: This study explores the mechanism of AAC in intervening heart failure (HF) using network pharmacology, molecular docking, and in vitro experimental validation. Methods: The “active component-target” network and the “drug-disease target” protein interaction network were constructed using Cytoscape 3.9.0 and STRING Database. …”
Get full text

Mapping patterns of thought onto brain activity during movie-watching by Raven Star Wallace, Bronte Mckeown, Ian Goodall-Halliwell, Louis Chitiz, Philippe Forest, Theodoros Karapanagiotidis, Bridget Mulholland, Adam Turnbull, Tamara Vanderwal, Samyogita Hardikar, Tirso RJ Gonzalez Alam, Boris C Bernhardt, Hao-Ting Wang, Will Strawson, Michael Milham, Ting Xu, Daniel S Margulies, Giulia L Poerio, Elizabeth Jefferies, Jeremy I Skipper, Jeffrey D Wammes, Robert Leech, Jonathan Smallwood

“…Contemporary views of ongoing thought argue that the ability to make sense of events in the ‘here and now’ depend on the neural processing of incoming sensory information by auditory and visual cortex, which are kept in check by systems in association cortex. …”
Get full text

PEMOCS: effects of a concept-guided, PErsonalized, MOtor-Cognitive exergame training on cognitive functions and gait in chronic Stroke—a randomized, controlled trial by S. K. Huber, S. K. Huber, R. H. Knols, R. H. Knols, J. P. O. Held, J. P. O. Held, M. Betschart, M. Betschart, S. Gartmann, S. Gartmann, N. Nauer, N. Nauer, E. D. de Bruin, E. D. de Bruin, E. D. de Bruin

“…Among secondary outcomes, the mobility domain of the HRQoL questionnaire, intrinsic visual alertness, cognitive flexibility, working memory, and outdoor walking speed as well as swing width (unaffected side) showed significant interaction effects in favour of the exergame group.DiscussionAdditional exergaming helped maintaining global cognitive functioning and showed encouraging effects in mobility and cognitive outcomes. …”
Get full text

Adalimumab Accounts for Long-Term Control of Noninfectious Uveitis Also in the Absence of Concomitant DMARD Treatment: A Multicenter Retrospective Study by Alice Bitossi, Alessandra Bettiol, Elena Silvestri, Gerardo Di Scala, Daniela Bacherini, Giuseppe Lopalco, Vincenzo Venerito, Florenzo Iannone, Antonio Vitale, Gian Marco Tosi, Domenico Prisco, Stanislao Rizzo, Claudia Fabiani, Luca Cantarini, Gianni Virgili, Lorenzo Vannozzi, Giacomo Emmi

“…This study was aimed at assessing the long-term ocular control of adalimumab (ADA) in a large real-world population with noninfectious primary or secondary uveitis, focusing on the steroid-sparing effect and on disease-modifying antirheumatic drug (DMARD) cotreatment. Methods. In this retrospective, multicenter study, the efficacy of ADA was evaluated in terms of ocular control, changes in best-corrected visual acuity (BCVA), corticosteroid-sparing effect, and drug retention rate, overall and stratified according to DMARD cotreatment. …”
Get full text

Iso-lating optimal automated external defibrillator signage: An international survey by Brandon Stretton, Gregory Page, Joshua Kovoor, Ammar Zaka, Aashray Gupta, Stephen Bacchi, Anjalee Amarasekera, Anoja Gunaratne, Aravinda Thiagalingam, Gopal Sivagangabalan, Pramesh Kovoor

“…The study suggests a need for more intuitive and visually distinct signage, such as the preferred yellow sign, to improve visibility and understanding, thereby enhancing AED accessibility and usage in OHCA.…”
Get full text

Non-invasive, non-enzymatic, non-serodiagnostic, and home-detecting paper-based “abnormal UA alarm” for early diagnosis of UA associated diseases by Qian Zhang, Hui’e Jiang, Zhijian Li, Lijuan Chen, Fengqian Yang, Jiamin Zhang, Bo Zhang, Xinhua Liu

“…Thus NIFP-SM equipped with NIFS resoundingly achieved efficient, rapid, and on-site visual detection of UA in saliva, urine-simulants, and foods. …”
Get full text

Gasless vNOTES vs. traditional vNOTES for benign gynecological disease: a randomized controlled clinical trial by Yanjun Wang, Kai Liu, Zhaolin Gong, Qinghua Huang, Qianqian Zhang, Dan Feng, Jiaojiao Chen, Ang Mao, Xia Yu, Lin Zhang, Yu Cui, Li He, Yonghong Lin

“…Here, we aimed to compare the hemodynamic profiles and outcomes of G-vNOTES with traditional vNOTES (T-vNOTES) in the treatment of patients with benign gynecologic disease. Methods A total of 120 patients with benign gynecologic disease were randomly assigned to G-vNOTES (n = 60) or traditional vNOTES (n = 60). …”
Get full text

Risk Factors for Intrauterine Device Malposition by Ann C. Frisse, Jay B. Louik, Isha A. Kachwala, Haotian Wu, Nicole Felix, Thammatat Vorawandthanachai, Karina Avila, Nerys C. Benfield

“…Objective: To identify risk factors for Intrauterine Device (IUD) malposition on ultrasound and develop a model to predict who may be at risk for IUD malposition. Methods: We performed a retrospective cohort study of IUD users with ultrasounds performed between July 2014 and July 2017 within a large urban medical system. …”
Get full text

Accelerated iTBS-Induced changes in resting-state functional connectivity correspond with cognitive improvement in amnestic MCI by Stephanie Aghamoosa, Sara A. Nolin, Andrew A. Chen, Kevin A. Caulfield, James Lopez, Katrina Rbeiz, Holly H. Fleischmann, Olivia Horn, Katrina Madden, Michael Antonucci, Gonzalo Revuelta, Lisa M. McTeague, Andreana Benitez

“…We correlated changes in cognition and connectivity of the target ROIs and networks; off-target ROI (primary visual) and networks served as negative controls. …”
Get full text

Effects of Varying Text Message Length and Driving Speed on the Disruptive Effects of Texting on Driving Simulator Performance: Differential Effects on Eye Glance Measures by Rimzim Taneja, Kawther Alali, Mohammed, Ki-Jana Malone, Brandon Buchanon, Ashley Blanchette, Dung Ho, Doreen Head, Randall Commissaris

“…Eye glances off the roadway are a measure of the visual distraction associated with texting while driving. …”
Get full text

Factors influencing the course of post-COVID-19-related symptoms: A bidirectional cohort study among employees in health and welfare services in Germany by Steinke, Lara, Peters, Claudia, Nienhaus, Albert, Bethge, Matthias, Koch, Peter

“…Kaplan-Meier curves were created to visualize the course of recovery. Factors influencing the time to recovery were analyzed using multivariate Cox regressions.Results: Of the 4,325 people contacted, 2,053 took part in the survey (response rate: 47%). 1,810 people were included in the analysis. …”
Get full text

Multispectral Imaging-Based System for Detecting Tissue Oxygen Saturation With Wound Segmentation for Monitoring Wound Healing by Chih-Lung Lin, Meng-Hsuan Wu, Yuan-Hao Ho, Fang-Yi Lin, Yu-Hsien Lu, Yuan-Yu Hsueh, Chia-Chen Chen

“…Conclusion: By detecting the StO2 levels of cutaneous tissues using the TOSD system with segmentation, the phases of wound healing were accurately distinguished. This method can support medical personnel in conducting precise wound assessments. …”
Get full text

Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional... by Aditya Kumar Singh, Akshat Mittal, Manvendra Singh Rawat, Sanjay Dalakoti, Anil Kumar Joshi, Pavneesh Kumar Lohan, Chandra Shekhar, Indrajit Das Bhoumik

“…Outcomes assessed included Harris Hip Score (HHS), pain using the Visual Analogue Scale (VAS), operative time, blood loss, time to weight-bearing, hospital stay and complications. …”
Get full text

Assessing the Use of BotulinumtoxinA for Hyperactive Urinary Tract Dysfunction a Decade After Approval: General Versus Local Anesthesia for BotulinumtoxinA Detrusor Injection by Heinrich Schulte-Baukloh, Apostolos Apostolidis, Catarina Weiss, Thorsten Schlomm, Sarah Weinberger, Dirk Höppner, Kathrin Haberecht, Carsten Waskow, Hendrik Borgmann, Jörg Neymeyer, Bernhard Ralla

“…We examined the level of anxiety and pain experienced by patients who wanted to have the procedure performed under LA or general anesthesia (GA). <b>Material and Methods</b>: Patients scheduled for OnabotA DI were able to choose the anesthesia procedure (LA or GA). …”
Get full text

Clinical characteristics and surgical treatment comparison of multisegmental spinal tuberculosis: a retrospective analysis by Zongqiang Yang, Zongqiang Yang, Zhangui Gu, Zhangui Gu, Qiang Liu, Qiang Liu, Long Ma, Le Fei, Le Fei, Ningkui Niu, Ningkui Niu, Jiandang Shi

“…BackgroundTo analyze the therapeutic efficacy of intervertebral surgery in the treatment of multisegmental spinal tuberculosis (MSTB) by evaluating its clinical outcomes and perioperative indicators, thereby providing evidence-based insights to optimize surgical strategies and improve clinical decision-making.MethodsThis retrospective cohort study analyzed 134 MSTB patients treated at our hospital between January 2000 and June 2022. …”
Get full text

Prediction of solid pseudopapillary tumor invasiveness of the pancreas based on multiphase contrast-enhanced CT radiomics nomogram by Dabin Ren, Liqiu Liu, Aiyun Sun, Yuguo Wei, Tingfan Wu, Yongtao Wang, Xiaxia He, Zishan Liu, Jie Zhu, Guoyu Wang

“…A radiomics nomogram was subsequently constructed and visualized by combining traditional CT independent predictors and radiomics signature. …”
Get full text

Effect of Traditional Chinese Medicine collapse stains combined with western medicine in treating acute herpes zoster (中药溻渍联合西医治疗急性期带状疱疹的疗效观察)... by YAO Meiyu (姚美玉), SUN Mingli (孙明丽), TANG Ling (唐玲), ZHOU Jie (周洁), CHEN Hong (陈宏)

“…The pain degree measured by Visual Analogue Scale (VAS) and treatment efficacy of the two groups were compared. …”
Get full text

Prevalence of falls and associations with family functioning among community-dwelling older adults in Guangzhou, China by Si-Yu Sun, Zhi-Wei Wang, Zhi-Li Peng, Le-Xin Yuan, Wen-Hao Yang, Wen-Jian Zhang, Jia-Min Chen, Wei-Quan Lin, Wei Zhu, Wei Zhu

“…Consequently, this study aims to investigate the prevalence and influencing factors of falls among community-dwelling older adults in Guangzhou, China, with a particular emphasis on the impact of family functioning.MethodsWe used a multi-stage stratified cluster random sampling technique to successfully survey 2,399 individuals aged 65 and above across 11 districts in Guangzhou City. …”
Get full text

Efficacy of topical Raphanus sativus seed powder mixed with honey versus hydroquinone 4 % cream in the treatment of melasma – A randomized controlled trial by Arshan Horti, Shaikh Nisar Ahmed Abbas, Shavana Fathima, Mamadapur Saba Abdul Razzaq, Arsheya Parvez Mistry, Farooqui Shazia Parveen, Nazim Husain

“…Secondary measures examined subjective nuances using a 100 mm visual analogue scale (VAS) and recorded the dermatology life quality index (DLQI) at baseline and the conclusion of the study. …”
Get full text

Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study by Ramón González-Matilla, Ramón González-Matilla, Ramón González-Matilla, Vanesa Abuín-Porras, Isabel Mínguez-Esteban, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo

“…ROM was assessed by goniometry, and pain perception was evaluated using the Visual Analog Scale during a Straight Leg Raise (SLR) test. …”
Get full text