Development of a predictive model for long-term care and support eligibility certification associated with dementia-related functional impairments: the IRIDE cohort study by Daichi Yamashiro, Hiroyuki Suzuki, Susumu Ogawa, Mari Yamashita, Hiroki Moriya, Hiroyuki Sasai, Shuichi P. Obuchi, Takumi Abe, Hiroshi Murayama, Takumi Hirata, Yoshinori Fujiwara, Shuichi Awata, Masahiro Akishita, Kenji Toba, IRIDE Cohort Study Investigators

“…Model 2, which included six predictors (age, history of stroke, history of heart disease, visual impairment, hearing impairment, and exercise habits), achieved a C-index of 0.73 (95% CI: 0.70–0.75) in the derivation dataset and 0.77 (95% CI: 0.73–0.81) in the validation dataset. …”
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Effects of proprioceptive exercise for knee osteoarthritis: a systematic review and meta-analysis by Yaoyu Lin, Debiao Yu, Debiao Yu, Debiao Yu, Xiaoting Chen, Peng Chen, Nan Chen, Bin Shao, Bin Shao, Bin Shao, Bin Shao, Qiuxiang Lin, Qiuxiang Lin, Fuchun Wu, Fuchun Wu, Fuchun Wu, Fuchun Wu

“…The present study sought to systematically evaluate the effects of proprioceptive exercise on symptoms and functional outcomes in patients with KOA, with a particular focus on balance performance.MethodsFollowing PRISMA guidelines, a comprehensive search was conducted across six electronic databases from the establishment of the database to January 21, 2025. …”
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Short-Term Effects of a Snack Including Fruit Juice Enriched with Vitamin D3, n-3 Fatty Acids, and Probiotics on Energy Intake and Satiety in Normal-Weight and Overweight Individua... by Christina Athanasaki, Nikolaos Zacharodimos, Sofia Tsitsou, Dionysia-Lydia Bothou, Stamatia Vitsou-Anastasiou, Olga S. Papadopoulou, Emilia Papakonstantinou

“…The participants rated their hunger, desire to eat, perceived fullness, thirst, preoccupation with food, and pleasure of eating on visual analogue scales (VAS) at the baseline and at 15–30 min intervals up to 7 h of the intervention. …”
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Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a... by Tingting Jiang, Zailin Yang, Xinyi Tang, Xinyi Tang, Na Fan, Zuhai Hu, Jieping Li, Tingting Liu, Yu Peng, Shuang Chen, Bingling Guo, Xiaomei Zhang, Yong Chen, Jun Li, Dehong Huang, Jun Liu, Yakun Zhang, Yakun Zhang, Xuefen Liu, Xia Wei, Zhanshu Liu, Haike Lei, Yao Liu

“…This study aimed to develop a machine learning-based early warning system (VTE-EWS) tailored to these patients.MethodsData from 1,141 lymphoma patients hospitalized for chemotherapy were retrospectively collected across four academic medical centers between February 2020 and February 2024. …”
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Efficacy of combining posterior scleral contraction and intravitreal C3F8 injection in high myopia with macular hole retinal detachment by Si Chen, Jie Ye, Qin-Tuo Pan, Fang Huang, Lin-Yan Zheng, Hui-Fang Ye, Yan-Feng Su, Yan Li, Shuang-Qian Zhu

“…Outcome measures included best-corrected visual acuity (BCVA), AL, optical coherence tomography (OCT) findings, and adverse events. …”
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Silver diamine fluoride alters microbial communities in subsurface dentinWhy Is This Important? by Rosalyn M. Sulyanto, DMD, MS, Clifford J. Beall, MS, PhD, Martin T. Berger, DMD, Christopher P. Goodell, DMD, Stephanie Koo, DMD, Fiorella Candamo, DMD, John R. Dickson, MD, PhD, Misun Kang, PhD, Sunita P. Ho, PhD, Man Wai Ng, DDS, MPH, Shahr B. Hashmi, BS, Eugene J. Leys, PhD, Ann L. Griffen, MS, DDS

“…Results: Viability testing of surface biofilm from carious lesions with or without SDF treatment visualized by confocal laser scanning microscopy revealed no change in microbial viability several weeks after SDF treatment. …”
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Efficacy of Different Acupuncture Techniques for Pain and Dysfunction in Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Jing Sun, Yi Liang, Kai-Tao Luo, Xiao-Mei Shao, Ming-Qi Tu, Xiao-Ting Wu, Fang Liu, Xin-Wei Li, Yi-Dan Chen, Qi-Fei Zhang, Cong-Hua Ji, Rong-Rong Li, Xiao-Yu Li, Fu Xu, Jian-Qiao Fang

“…EA is the most effective method of alleviating pain intensity in treating KOA. …”
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Identification of maize leaf diseases using red, green, blue-based images with convolutional neural network (CNN) and residual network (ResNet50) models by Basani Lammy Nkuna, Khaled Abutaleb, Johannes George Chirima, Solomon W. Newete, Adriaan Johannes van der Walt, Adolph Nyamugama

“…However, it is susceptible to diseases that drastically reduce yields if not controlled. Traditional methods of disease detection of visual inspections are often inaccurate and uncertain. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…The visually-based immunochromatographic test (ICT) described herein allows for quick detection and quantification of IgG and IgM FH-FHAA complexes in human EDTA-plasma or serum. …”
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Prevalence of eating disorders in South Asian countries: a systematic analysis of Global Burden of Disease (1990–2021) by Prakasini Satapathy, Vijay Kumar, Mahalaqua Nazli Khatib, Lalji Baldaniya, Suhas Ballal, V. Kavitha, Laxmidhar Maharana, Renu Arya, Ganesh Bushi, Muhammed Shabil, Rukshar Syed, Manika Gupta, Sunil Kumar, Sabah Ansar, Sanjit Sah, Diptismita Jena, Edward Mawejje

“…Geospatial patterns and temporal changes were visualized using QGIS software. The correlation between the Sociodemographic Index (SDI) and the DALY rate was assessed using R software. …”
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Extracellular vesicle GABA responds to cadmium stress, and GAD overexpression alleviates cadmium damage in duckweed by Zhanpeng Sun, Zhanpeng Sun, Ziyang Qu, Yuman He, Yujie Han, Yun Xing, Sizheng Liu, Yi Hu, Yumeng Jiang, Yiqi Yu, Yuanyuan Liu, Weibo Sun, Lin Yang

“…While γ-aminobutyric acid (GABA) is known to accumulate rapidly under environmental stress, the real-time dynamics of GABA signaling and its mechanistic link to stress adaptation remain poorly understood.MethodsIn this study, a sensitive GABA biosensor, iGABASnFR, was introduced into plants for the first time to monitor GABA signaling. …”
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Acupuncture for cancer-related insomnia: An evidence mapping by Zining Guo, Liying Wang, Yuting Wang, Wenhao Liu, Yi Zhao, Xiaorong Tang, Run Lin, Zhennan Wu, Shaoyang Cui, Nenggui Xu

“…The quality of studies was assessed using the Cochrane Risk of Bias 2.0 (RoB 2.0) tool, and key characteristics visualized EM. Finally, Acupoint data were systematically summarized. …”
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Vibrotactile Stimulation in Lower Extremity Amputation Patients Using a Noninvasive Vibration Device: A Pilot Study by Floris V. Raasveld, MD, Jenna Daddario, PA, Wen-Chih Liu, MD, Dun-Wei Huang, MD, Rachel E. Cross, BA, Karan Amin, BA, Arthur Graham, CP, David Crandell, MD, David Hao, MD, Ian L. Valerio, MD, MS, MBA, FACS, Kyle R. Eberlin, MD

“…Pain, function, mental health, and satisfaction metrics were assessed using the visual analog scale, patient-reported outcomes measurement information system surveys, and various gait tests at baseline and follow-up. …”
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Multimodal analgesia with parasternal plane block protocol within an enhanced recovery after cardiac surgery program decreases opioid useCentral MessagePerspective by Marc Darras, MD, Clément Schneider, MD, Sandrine Marguerite, MD, Saadé Saadé, MD, Anne-Lise Maechel, MD, Walid Oulehri, MD, Olivier Collange, MD, PhD, Jean-Philippe Mazzucotelli, MD, PhD, Paul-Michel Mertes, MD, PhD, Michel Kindo, MD, PhD

“…The secondary outcomes were postoperative visual analog scale (VAS) scores, mechanical ventilation duration, ileus, delirium, bronchopneumonia, and length of ICU stay. …”
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Pharmacopuncture therapy for adhesive capsulitis: A pragmatic randomized controlled pilot study by Doori Kim, Kyoung Sun Park, Sun-A Kim, Ji Yeon Seo, Hyun-Woo Cho, Yoon Jae Lee, Changsop Yang, In-Hyuk Ha, Chang-Hyun Han

“…The primary outcome was the NRS score for shoulder pain, and the secondary outcomes were the visual analog scale (VAS), Shoulder Pain and Disability Index (SPADI), range of motion (ROM), patient global impression of change (PGIC), EuroQol 5-Dimension 5-Level (EQ-5D-5L), and Short Form 12 Health Survey (SF-12) scores. …”
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Prevalence of the anti-CASPR2 autoantibody in patients with somatic symptom disorder accompanied by medically unexplained pain by Shingo Katayama, Gayatri Nayanar, Takayuki Suga, Motoko Watanabe, Chihiro Takao, Yojiro Umezaki, Hidehiko Takahashi, Akira Toyofuku, Hiroki Shiwaku

“…Among the 264 patients enrolled, 231 with oral dysesthesia (including oral cenesthopathy) were assessed for clinical symptom severity using the Visual Analog Scale (VAS), Pain Catastrophizing Scale (PCS), and Somatic Symptom Scale-8 (SSS-8). …”
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Development and validation of a diagnostic model for tuberculous meningitis based on laboratory data by Fuyong Liu, Zheng Li, Xuejiao Li, Wei Hong, Yanlin Zhou, Yungang Han, Shuang Xia, Jiao Tan, Yunchang Yang, Shiqi Li, Zhi Li, Wenyi He, Huihui Chen, Pengxiang Li, Yali Wang, Xu Yang, Jingcai Gao, Wei Wang

“…ObjectiveWe developed and validated a diagnostic scoring system for tuberculous meningitis (TBM) using 13 laboratory parameters, comparing tuberculous meningitis (TBM) and non-tuberculous meningitis (non-TBM).MethodsThis study enrolled patients diagnosed with meningitis. …”
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Anesthesiologic management of pregnant women with SARS-COV-2 infection undergoing cesarean delivery by Antonio Coviello, Concetta Posillipo, Ludovica Golino, Carlo De Angelis, Elisabetta Gragnano, Gabriele Saccone, Marilena Ianniello, Gaetano Castellano, Annachiara Marra, Alfredo Maresca, Maria Vargas, Giuseppe Servillo

“…All pregnant women had pain visual analog scale (VAS) ≤3, and no pregnant women required rescue dose. …”
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Microstructural and functional abnormalities of the locus coeruleus in freezing of gait in Parkinson's disease by Huimin Sun, Caiting Gan, Xingyue Cao, Yongsheng Yuan, Heng Zhang, Chenhui Wan, Jiaxin Shi, Xufeng Wang, Youyong Kong, Tao Feng, Kezhong Zhang

“…Conclusions: LC degeneration may disrupt motor and compensatory network integration, especially in visual-motor pathways, contributing to FOG.…”
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Relationship between the Degrees of Itch and Serum Lipocalin-2 Levels in Patients with Psoriasis by Norie Aizawa, Yozo Ishiuji, Mitsutoshi Tominaga, Sanae Sakata, Nobuaki Takahashi, Koichi Yanaba, Yoshinori Umezawa, Akihiko Asahina, Utako Kimura, Yasushi Suga, Kenji Takamori, Hidemi Nakagawa

“…The degree of itch was assessed using a visual analog scale (VAS), and disease severity was determined by measuring psoriasis area and severity index (PASI) and scoring atopic dermatitis (SCORAD). …”
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