Combining patient-reported outcome measures to screen for active disease in rheumatoid arthritis and psoriatic arthritis by Annette H M van der Helm-van Mil, Pascal H P de Jong, Paco M J Welsing, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Paul Baudoin, Lindy-Anne Korswagen, Selinde V J Snoeck Henkemans, Agnes E M Looijen, Gonul Hazal Koc

“…Objectives To investigate whether a combination of general health (Visual Analogue Scale (VAS)), Health Assessment Questionnaire-Disability Index (HAQ-DI), pain (VAS/Numerical Rating Scale (NRS)), quality of life (EQ-5D), fatigue (VAS/NRS) and presenteeism (0%–100% productivity loss) could aid as a screening tool to detect active disease in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA).Methods RA patients from the tREACH trial and TARA trial (n=683) and PsA patients from the DEPAR cohort (n=525) were included. …”
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Increased Risk of Central Serous Chorioretinopathy among Patients with Nonorganic Sleep Disturbance by Peng-Tai Tien, Chien-Yu Lai, Chun-Ju Lin, Wen-Lu Chen, Po-Kang Lin, Chih-Hsin Muo, Yi-Yu Tsai, Lei Wan, Wen-Chao Ho, Hui-Ju Lin

“…Patients with central serous chorioretinopathy (CSC) typically present with acute visual impairment and metamorphopsia. The disease previously has been associated with psychological stress. …”
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Systemizing and Transforming Preterm Oral Feeding Through Innovative Algorithms by Rena Rosenthal, Jean Chow, Erin Sundseth Ross, Rudaina Banihani, Natalie Antonacci, Karli Gavendo, Elizabeth Asztalos

“…These resources included detailed instructions, visual aids, and step-by-step guides to help staff understand and apply the algorithms effectively. …”
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An Effective and Safe Laser Treatment Strategy of Fractional Carbon Dioxide Laser for Chinese Populations with Periorbital Wrinkles: A Randomized Split-Face Trial by Xianglei Wu, Qingqing Cen, Jian Jin, Wei Gao, Ying Shang, Linting Huang, Xiaoxi Lin

“…Both the investigators’ and patients’ visual evaluations demonstrated a consistent efficacy rate of 68.2% without differences between groups. …”
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Development and temporal external validation of a novel nomogram for predicting one-year mortality in the older adult with hip fracture by Yangfan Gong, Kai Zhang, Wei Chen, Qiqi Yang, Mingyue Shi, Zhao Dong, Zhuohao Yin, Yuyu Zhang, Wei Ge

“…The discriminatory power of the model and its accuracy were monitored by utilizing receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis. Furthermore, visual risk applications were developed to enhance usability.ResultsThe one-year mortality is 16.8%. …”
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Efficacy of ultrasound-guided intensive silver needles in the treatment of shoulder pain by LUO Jia, LIU Jitong, ZHANG Weiwei, LIAO Qian, LIAO Yongqiong

“…Objective To investigate the effects of ultrasound.guided intensive silver needles on the efficacy, pain, shoulder function, inflammatory factors and pain.causing substances in patients with shoulder joint pain. Methods A total of 92 patients with frozen shoulder admitted to Hunan Provincial People..s Hospital from January 2022 to May 2023 were selected, and were divided into two groups with 46 cases in each group by random number table method. …”
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Epigenetic modifications are associated with mRNA and cytokine expression changes in chronic rhinosinusitis: a multiomics study from the United States by Devyani Lal, Tripti Brar, Chantal McCabe, Erik Jessen, Nitish Kumar, Pedro Lança Gomes, Michael J. Marino, Amar Miglani, Hirohito Kita

“…We therefore performed a multi-omics study integrating epigenetic (DNA methylation), transcriptomic (mRNA), and proteomic (cytokine) data of CRS sinonasal tissue to visualize interactions amongst these modalities to study our hypothesis.MethodsSinonasal tissue was collected from 14 prospectively enrolled CRS and control subjects. …”
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Aspartate aminotransferase-to-platelet ratio index as a novel predictor of early mortality in heat stroke patients: a multi-centre retrospective study by Min Wang, Yun Li, Yuan Cao, Meng-Meng Yang, Fu-Jing Liu, Jie Jiao, Sheng-Yuan Wang, Bin Song, Lu Wang, Yi-Qi Wu, Hong-Jun Kang

“…Restricted cubic splines (RCS) were utilized to visualize the relationship between APRI and 28-day mortality risk. …”
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Effect of Traditional Chinese Medicine ointment rubbing therapy in the treatment of primary dysmenorrheal (中药膏摩治疗原发性痛经疗效观察) by CAO Lei (曹蕾), ZHANG Lijun (张丽君), KONG Xiaochun (孔晓春), CHEN Hong (陈宏)

“…The pain degree was evaluated by Visual Analogue Scale (VAS), and the effect of intervention was compared between two groups. …”
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AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma by David J. Taylor Gonzalez, MD, Mak B. Djulbegovic, MD, MSc, Meghan Sharma, MD, MPH, Michael Antonietti, BS, Colin K. Kim, BS, Vladimir N. Uversky, PhD, DSc, Carol L. Karp, MD, Carol L. Shields, MD, Matthew W. Wilson, MD

“…Subjects: Genetic data from patients diagnosed with UM were analyzed, explicitly focusing on missense mutations sourced from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Methods: We identified missense mutations frequently observed in UM using the COSMIC database, assessed their potential pathogenicity using AlphaMissense, and visualized mutations using AlphaFold. …”
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Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…Postoperative pancreatitis developed in 2 cases (5.9%, 2/34), and hyperamylasemia occurred in 5 cases (14.7%, 5/34). The postprocedure visual analogue scale (VAS) score for abdominal pain significantly decreased from 6 to 1 (P < 0.001). …”
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Outcomes of Bilateral Scandinavian Total Ankle Replacement: A Detailed Analysis of Implant Survivability and Patient-Reported Outcomes by Alexandra Hunter Aitchison BS, Albert T. Anastasio MD, Kevin A. Wu BS, Emily Poehlein MB, Cynthia Green PhD, Samuel B. Adams MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD

“…This study aimed to evaluate the survivability and patient-reported outcomes of simultaneous bilateral STAR, focusing on implant survival rates and improvements in quality of life, function, and pain relief. Methods: A retrospective cohort study was conducted on all patients managed with primary TAR performed simultaneously with bilateral STAR prostheses at our institution from July 1998 to February 2008. …”
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Comparative efficacy of the modified minimally invasive “Parachute Technique” vs. the intermuscular GAP Approach in proximal humeral fracture management: a prospective study by Jia Jia Wei, Jia Jia Wei, Jun Li, Tao Chen, Hong Chi Yi, Wen Tao Zhao, Tian Tian, Jian Wei Wang

“…Secondary outcomes included pain relief (Visual Analog Scale), shoulder function (Neer Shoulder Score), and fracture healing (Radiographic Union Scoring System, RUST).ResultsThe Parachute Technique group had significantly shorter operation times (97.25 ± 16.09 min vs. 119.75 ± 17.13 min, p < 0.001) and lower blood loss (99.00 ± 25.06 ml vs. 207.50 ± 44.47 ml, p < 0.001). …”
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Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…IntroductionElectrographic flow (EGF) mapping is an FDA 510(k)-cleared method for visualizing atrial activation wavefronts in atrial fibrillation (AF). …”
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Identification of subgroups of early-stage mycosis fungoides patients with increased itch and impaired quality of life by Julia Nenonen, Anna H. Winther, Anna H. Winther, Pontus Jonsson, Pontus Jonsson, Lina U. Ivert, Lina U. Ivert, Hanna Brauner, Hanna Brauner

“…This single center study investigated associations between QoL/itch/depressive symptoms and clinical phenotypes in patients with CTCL with particular focus on early MF-stages.MethodsPatients were included during routine dermatological care. …”
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Hyperreflective focuses as a biomarker of multiple sclerosis progression by A. Zh. Fursova, M. Y. Zubkova, M. A. Vasilyeva, Y. A. Gamza, A. S. Derbeneva, I. F. Nikulich, N. A. Malkova, A. I. Prokaeva, P. N. Pozdnyakova

“…Purpose: to identify the intraretinal hyperreflective foci (HRF), their specific characteristics, localization features and correlations with the duration of the disease, type of course and previous episodes of optic neuritis (ON) in multiple sclerosis (MS) patients using a high-resolution OCT scanning protocol. Materials and methods. The study included 160 patients (318 eyes) divided into 8 groups, i.e. …”
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Feasibility and safety of transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) panhysterectomy: a polycentric retrospective study by Panlian Qian, Weimin Chen, Bin Su, Yao Chen, Wulin Shan, Huimin Tang, Weiwei Wei, Huihui Wang, Bairong Xia, Jiming Chen

“…The operation duration, intraoperative blood loss, postoperative exsufflation time, postoperative activity time, hospital stay, treatment cost, 6 h activities of daily living (ADL) score after the operation, cosmetic score, visual analog score, and complications were observed in the two groups. …”
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Outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries: a single-center study by Shengwen Xiang, Zhen Hu, Zihao Ren, Guangqing Cai, Zhijiang Ao, Weiguo Hu, Yangbo Liu, Xing Li, Licheng Wei

“…Knee joint function was evaluated using the International Knee Documentation Committee (IKDC) score, Lysholm score, Tegner activity score, visual analog scale (VAS) score, and range of motion. …”
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The influence of type 2 diabetes mellitus on clinical manifestations of osteoarthritis by E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, E. P. Sharapova, N. M. Savushkina, K. M. Mikhailov, T. A. Raskina, I. B. Vinogradova, E. N. Otteva, E. V. Zonova, O. N. Anoshenkova, A. M. Lila

“…Objective: to investigate in a multicenter study relationship between type 2 diabetes mellitus (DM) and clinical manifestations of osteoarthritis (OA). Material and methods. The study involved 767 patients aged 40–75 years with a confirmed diagnosis of stage I–III knee OA who had signed an informed consent form. …”
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The dose-dependent efficacy of esketamine in spinal surgery with intraoperative neuroelectrophysiological monitoring: a randomized controlled trial by Chunyan Lin, Chunyan Lin, Jianlin Wang, Long Zhang, Long Zhang, Liyong Yuan, Guanyi Liu, Guanyi Liu, Miao Zhu, Liangguang Zhang

“…The study measured vital signs, consumption of anesthetics, operation time, blood loss, awakening time in the postanesthesia care unit (PACU), visual analog scale (VAS) pain score, quality of recovery (QoR) -15 score, and dosage of supplementary analgesics. …”
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