Human umbilical cord mesenchymal stem cell-derived exosomes enhance follicular regeneration in androgenetic alopecia via activation of Wnt/β-catenin pathway by Aiqing Yu, Yujun Zhang, Saifeng Zhong, Zhizhen Yang, Mingming Xie

“…The effects of MSC-derived exosomes (MSC-Exo) on hair follicle growth were evaluated through transparent skin visualization, hematoxylin and eosin staining, and immunofluorescence assays. …”
Get full text

Clinical application and feasibility of capsule endoscopy in children at a medical center in central Taiwan by Yi-Jun Liao, Wan-Tzu Lin, Szu-Chia Liao, Shao-Ju Lin, Yen-Chu Huang, Meng-Che Wu, Chieh-Chung Lin

“…Background purpose: Capsule endoscopy (CE) is a noninvasive examination for excellent visualization of small bowel mucosal lesions. We aimed to evaluate the clinical efficacy and safety of CE in pediatric patients. …”
Get full text

The potential mechanism of Huangqin for treatment of systemic lupus erythematosus based on network pharmacology, molecular docking and molecular dynamics simulation by Shuting Zheng, Hui Yang, Jialing Wu, Ou Jin, Xi Zhang

“…Method Employing the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) database to identify the active chemical components of Huangqin, searching for target genes related to SLE through GeneCards and the KEGG database, extracting the SLE expression gene profile from the GEO database to identify SLE-related targets, and identifying Huangqin-SLE interaction targets using Venny diagrams; Constructing protein interaction networks using the STRING database, identifying core targets with Cytoscape software, and conducting protein clustering analysis; Importing the common targets into the Database for Annotation, Visualization and Integrated Discovery (DAVID) for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. …”
Get full text

Network analysis of the relationships between voice behavior and team psychological safety climate among Chinese nurses by Miaoji Lu, Ruinan Xia, Rui Wang, Xiaofang Zou

“…Network analysis was employed to visualize the interactive relationships among variables. …”
Get full text

Global ischemic heart disease burden attributable to environmental risk factors, 1990–2021: an Age-Period-Cohort analysis by Rui Su, Rui Su, Wangchu Ze, Wangchu Ze, Ruiyu Huang, Yanxia Guo, Gang Liu, Baolu Zhang

“…Data processing and visualization were conducted using R version 4.4.3.ResultsBetween 1990 and 2021, global environmental IHD deaths rates decreased by 31.13% and DALYs rates by 29.85%. …”
Get full text

Anatomic and Topographic Vitreous and Vitreoretinal Interface Features in Proliferative Diabetic Vitreoretinopathy by N. M. Kislitsyna, S. V. Novikov, S. V. Kolesnik, A. I. Kolesnik, M. P. Veselkova

“…“Vitreocontrast” suspension allows to visualize posterior cortex changes during different stages of PDR. …”
Get full text

Establishing an intraoperative, mobile CBCT-based workflow for gynecologic brachytherapy: primary experience and benefit assessment by Andre Karius, Andre Karius, Vratislav Strnad, Vratislav Strnad, Christoph Bert, Christoph Bert, Rainer Fietkau, Rainer Fietkau, Ricarda Merten, Ricarda Merten, Claudia Schweizer, Claudia Schweizer

“…Image quality was assessed by considering the applicator visualization and contrast–noise ratio (CNR) between tissues. …”
Get full text

Nursing Students' Perspectives on Integrating Artificial Intelligence Into Clinical Practice and Training: A Qualitative Descriptive Study by Moustaq Karim Khan Rony, Sumon Ahmad, Dipak Chandra Das, Sabren Mukta Tanha, Tuli Rani Deb, Mosammat Ruma Akter, Mst. Amena Khatun, Md Ibrahim Khalil, Umme Rabeya Peu, Mst. Rina Parvin, Daifallah M. Alrazeeni, Fazila Akter

“…Credibility was ensured through member checking, dependability via an audit trail, and confirmability through peer debriefing. Data visualization tools were used to map thematic relationships effectively. …”
Get full text

Global incidence and trends of ocular cancer: A bibliometric analysis by Hang Xu, Alexander C. Rokohl, Xiaojun Ju, Yongwei Guo, Xincen Hou, Wanlin Fan, Ludwig M. Heindl

“…Use VOSviewer and CiteSpace for network visualization and Microsoft Excel for data management. …”
Get full text

Diagnostic potential of salivary microbiota in persistent pulmonary nodules: identifying biomarkers and functional pathways using 16S rRNA sequencing and machine learning by Xiao Zeng, Qiong Ma, Chun-Xia Huang, Jun-Jie Xiao, Xi Fu, Yi-Feng Ren, Yu-Li Qu, Hong-Xia Xiang, Mao Lei, Ru-Yi Zheng, Yang Zhong, Ping Xiao, Xiang Zhuang, Feng-Ming You, Jia-Wei He

“…A high-accuracy LightGBM model was developed, identifying six core genera—Fusobacterium, Solobacterium, Actinomyces, Porphyromonas, Atopobium, and Peptostreptococcus—as pPNs biomarkers. Additionally, a visualization pPNs risk prediction system was developed. …”
Get full text

Analysis of the marketing activities in the blood service: bibliometric analysis by Liliya Khomenko, Liudmyla Saher, Jan Polcyn

“…Methodological tools of the research methods were 2000-2019 years. The object of research is 262 relevant articles published in 25 journals over the period 2000–2019 because, namely, they explain the essence of marketing activity in blood service facilities. …”
Get full text

Carpal Tunnel Release with Ultrasound Guidance Versus Open and Mini-Open Carpal Tunnel Release: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Seper Ekhtiari, MD, MSc, Mark Phillips, PhD, Dalraj Dhillon, BSc, Ali Shahabinezhad, MD, Conner McMains, MD, Bill Dzwierzynski, MD, Mohit Bhandari, MD, PhD

“…Carpal tunnel release with ultrasound guidance allows the procedure to be performed through a small, nonpalmar incision while maintaining visualization of critical anatomy and may confer benefits in terms of early recovery and incision-related complications. …”
Get full text

OBSCN undergoes extensive alternative splicing during human cardiac and skeletal muscle development by Ali Oghabian, Per Harald Jonson, Swethaa Natraj Gayathri, Mridul Johari, Ella Nippala, David Gomez Andres, Francina Munell, Jessica Camacho Soriano, Maria Angeles Sanchez Duran, Juha Sinisalo, Heli Tolppanen, Johanna Tolva, Peter Hackman, Marco Savarese, Bjarne Udd

“…OBSCN undergoes extensive and complex alternative splicing, which is the main reason that its splicing regulation associated with skeletal and cardiac muscle development has not previously been thoroughly studied. Methods We analyzed RNA-Seq data from skeletal and cardiac muscles extracted from 44 postnatal individuals and six fetuses. …”
Get full text

Development and usability testing of an integrated geriatric care model (SMART system) to promote integrated home-based geriatric care by Rongrong Guo, Huan Fan, Shuqin Xiao, Ziling Zheng, Fangyu Yang, Yanyan Xiao, Xue Yang, Ying Wu

“…This study aimed to address the gap by developing an integrated geriatric care model (SMART system) using a knowledge-based clinical decision support system (CDSS) architecture inspired by the principle of neural reflex and evaluate the usability of the SMART system. Methods The development of our SMART system was guided by the knowledge-based Clinical Decision Support System architecture and the principle of neural reflexes, which included 5 phases: (1) functional design; (2) architecture and database design; (3) security measures design; (4) user interface and visualization design; (5) prototypes development and iteratively testing. …”
Get full text

Advancing Diabetic Retinopathy Screening: A Systematic Review of Artificial Intelligence and Optical Coherence Tomography Angiography Innovations by Alireza Hayati, Mohammad Reza Abdol Homayuni, Reza Sadeghi, Hassan Asadigandomani, Mohammad Dashtkoohi, Sajad Eslami, Mohammad Soleimani

“…Optical Coherence Tomography Angiography (OCTA) now enables non-invasive, layer-specific visualization of the retinal vasculature, facilitating more precise identification of early microvascular changes. …”
Get full text

Ensemble learning to predict short birth interval among reproductive-age women in Ethiopia: evidence from EDHS 2016–2019 by Jenberu Mekurianew Kelkay, Deje Sendek Anteneh, Henok Dessie Wubneh, Abraham Dessie Gessesse, Gebeyehu Fassil Gebeyehu, Kalkidan Kassahun Aweke, Mikiyas Birhanu Ejigu, Mathias Amare Sendeku, Kirubel Adrissie Barkneh, Hasset Girma Demissie, Wubshet D. Negash, Birku Getie Mihret

“…The dataset was then imported into a Jupyter notebook for further detailed analysis and visualization. An ensemble Machin learning algorithm using different classification models were implemented. …”
Get full text

Development and validation of a novel predictive model for dementia risk in middle-aged and elderly depression individuals: a large and longitudinal machine learning cohort study by Xuan Xiao, Yihui Li, Qiaoboyang Wu, Xinting Liu, Xu Cao, Maiping Li, Jianjing Liu, Lianggeng Gong, Xi-jian Dai

“…For practical implementation, we deployed the optimal model to a web application for visualization and dementia risk assessment, named DRP-Depression. …”
Get full text

Evaluating the Effectiveness and Complications of Robotic vs Other Surgery Techniques for Mitral Valve Repair or Replacement: A Comprehensive Systematic Review and Meta-analysis by Carlos Esteban Vidal Valderrama, Ramon Isaac Zavala Garcia, Yeisson Rivero Moreno, Raul Antunez Perez, Jessica Edith Acevedo Rodriguez, Vanessa Pamela Salolin-Vargas, Leopoldo David Trujillo-García, Mauricio Alejandro Saldaña-Ruiz, Noe Alejandro Zúñiga González, Vanessa Jarelly Rodríguez-Huerta, Carolina Cantú Navarro

“…Traditional open-heart surgery has long been the standard approach, offering reliable outcomes through direct visualization and access to the heart. However, advancements in minimally invasive techniques, particularly robotic-assisted surgery, have introduced new possibilities in the field of cardiac surgery and benefits to the patients regarding the outcomes and complications. …”
Get full text

Development and validation of a model for predicting in-hospital mortality in patients with sepsis-associated kidney injury receiving renal replacement therapy: a retrospective coh... by Caifeng Li, Ke Zhao, Qian Ren, Lin Chen, Ying Zhang, Guolin Wang, Keliang Xie

“…Additionally, a clinical nomogram was developed to facilitate the interpretation and visualization of the LR model.ResultsA total of 1663 adults were ultimately enrolled and randomly allocated into the training cohort (n = 1164) or the testing cohort (n = 499). …”
Get full text

Isolation and in silico analysis of a new subclass of parasporin 4 from Bacillus thuringiensis coreanensis by Thais N. F. Santos, Raquel O. Moreira, Jardel D. B. Rodrigues, Luis A. C. Rojas, Jackson A. M. Souza, Janete A. Desidério

“…Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) gel analyses allowed the visualization of the inactive and active PS4 protein from the positive strain, after solubilization and activation with Proteinase K. …”
Get full text