Three-Dimensional-Printed Isoniazid Chewable Gels for On-Demand Latent Tuberculosis Treatment in Children by Amanda de O. E. Moreira, Lêda Maria S. Azevedo Neta, Márcia Pietroluongo, Ana Paula dos S. Matos, Beatriz B. Correa, Beatriz H. Ortiz, André da S. Guimarães, Marcio Nele, Carollyne M. Santos, Ana Elizabeth C. Fai, Maria Helena Gonçalves, Flávio M. Shimizu, Monique S. Dos Santos, Rosemberg B. Moure, Diogo D. Nascimento, André Luis de A. Guimarães, Saint Clair dos S. G. Junior, Alessandra L. Vicosa, Lucio M. Cabral

“…This study aims to develop innovative 3D-printed chewable gels containing INH for LTBI treatment. <b>Methods</b>: The gels were formulated using gelatin and carrageenan gum, sugar-free sweeteners, and flavoring. …”
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Presence of Potential Enteropathogenic Bacteria in Cats and Association With Diarrhea in Multicat Households by Kirsten Bogedale, Ute Klein‐Richers, Sandra Felten, Michèle Bergmann, Nikola Pantchev, Yury Zablotski, Jan Suchodolski, Kathrin Busch, Stefan Unterer, Katrin Hartmann

“…Animals In total, 234 cats from 41 privately owned catteries were included. Methods In this prospective study, feces were evaluated for consistency according to a visual scoring system (Purina Fecal Score). …”
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Using Key Predictors in an SVM Model for Differentiating Spinal Fractures and Herniated Intervertebral Discs in Preoperative Anesthesia Evaluation by Shih-Ying Yang, Shih-Yen Hsu, Yi-Kai Su, Nan-Han Lu, Kuo-Ying Liu, Tai-Been Chen, Kon-Ning Chiu, Yung-Hui Huang, Li-Ren Yeh

“…Accurate differentiation between these conditions is crucial for effective treatment, particularly in the context of preoperative anesthesia evaluation, where understanding the underlying condition can influence anesthesia planning and pain management. <b>Methods and Materials:</b> This study presents a Support Vector Machine (SVM) model designed to distinguish between spinal fractures and HIVDs using key clinical predictors, including age, gender, preoperative Visual Analog Scale (VAS) pain scores, and the number of spinal fractures. …”
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‘It Just Makes Sense to Me’: A qualitative study exploring patient decision‐making and experiences with prostate MRI during active surveillance for prostate cancer by Ryan Sutherland, Cary P. Gross, Xiaomei Ma, Farah Jeong, Tyler M. Seibert, Matthew R. Cooperberg, William J. Catalona, Shellie D. Ellis, Stacy Loeb, Dena Schulman‐Green, Michael S. Leapman

“…Abstract Introduction Although prostate magnetic resonance imaging (MRI) is commonly used in the diagnosis, staging and active surveillance of prostate cancer, little is known about patient perspectives on MRI. Methods We performed a qualitative study consisting of in‐depth, semi‐structured interviews of patients with low‐ and intermediate‐risk prostate cancer managed with active surveillance. …”
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An exploratory assessment of GPT-4o and GPT-4 performance on the Japanese National Dental Examination by Masaki Morishita, Hikaru Fukuda, Shino Yamaguchi, Kosuke Muraoka, Taiji Nakamura, Masanari Hayashi, Izumi Yoshioka, Kentaro Ono, Shuji Awano

“…Further studies are needed to evaluate GPT-4o’s capabilities with visual materials and in diverse question sets to fully ascertain its utility in educational settings.…”
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Development of a nomogram for predicting renal survival in patients with biopsy-proven diabetic nephropathy by Zishan Lin, Zishan Lin, Zishan Lin, Tao Hong, Tao Hong, Tao Hong, Wenfeng Wang, Wenfeng Wang, Wenfeng Wang, Shidong Xie, Shidong Xie, Shidong Xie, Xiaohong Zhang, Xiaohong Zhang, Xiaohong Zhang, Xuan Tao, Feng Yang, Caiming Chen, Caiming Chen, Caiming Chen, Dewen Jiang, Dewen Jiang, Dewen Jiang, Jianxin Wan, Jianxin Wan, Jianxin Wan, Hong Chen, Yanfang Xu, Yanfang Xu, Yanfang Xu

“…This study aims to develop a non-invasive predictive model to evaluate the risk and timing of ESKD onset in this population.MethodsThis study retrospectively analyzed data from 140 biopsy-confirmed DN patients. …”
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Individualized prediction of multi-domain intelligence quotient in bipolar disorder patients using resting-state functional connectivity by Xiaoyu Li, Wei Wei, Linze Qian, Xiaojing Li, Mingli Li, Ioannis Kakkos, Qiang Wang, Hua Yu, Wanjun Guo, Xiaohong Ma, George K. Matsopoulos, Liansheng Zhao, Wei Deng, Yu Sun, Tao Li

“…The present study aimed to infer BD patients’ IQ scores at the individual level using a prediction model. Methods: We applied a cross-validated Connectome-based Predictive Modeling (CPM) framework using resting-state fMRI functional connectivity (FCs) to predict BD patients’ IQ scores, including verbal IQ (VIQ), performance IQ (PIQ), and full-scale IQ (FSIQ). …”
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Development and validation of a diagnostic model for tuberculous meningitis based on laboratory data by Fuyong Liu, Zheng Li, Xuejiao Li, Wei Hong, Yanlin Zhou, Yungang Han, Shuang Xia, Jiao Tan, Yunchang Yang, Shiqi Li, Zhi Li, Wenyi He, Huihui Chen, Pengxiang Li, Yali Wang, Xu Yang, Jingcai Gao, Wei Wang

“…ObjectiveWe developed and validated a diagnostic scoring system for tuberculous meningitis (TBM) using 13 laboratory parameters, comparing tuberculous meningitis (TBM) and non-tuberculous meningitis (non-TBM).MethodsThis study enrolled patients diagnosed with meningitis. …”
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Clinical manifestation and management of severe blepharokeratoconjunctivitis combined with corneal perforation by Xu Li, Ping Hou, Xiao-Lin Qi, Su-Xia Li, Wei-Yun Shi, Hua Gao, Ting Zhang

“…A paired t-test was used to compare the uncorrected visual acuity (UCVA) before and after surgery for the perforated eye. …”
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Strengthening Mental Health Though Resilience in Nursing Students: A Protocol for a Comprehensive Scoping Review by Emilia Batista Mourão Tiol, Rauer Ferreira Franco, Amanda Oliva Spaziani, Gabriela Gouvea Silva, Emerson Roberto dos Santos, Vânia Maria Sabadoto Brienze, Alba Regina de Abreu Lima, Sônia Maria Maciel Lopes, Josimerci Ittavo Lamana Faria, Alexandre Lins Werneck, Nádia Antônia Aparecida Poletti, Rafael Guerra de Aquino, Adriana Luiz Sartoreto Mafra, Andreia Mura Peres, Elena Carla Batista Mendes, Thaisa Fernanda Queiroz de Souza, Valéria da Silva Campoi, Luiz Fernando Campoi, Silvia Regina dos Santos Benitez, Patrícia Freire de Vasconcelos, Júlio César André

“…Grey literature sources will also be searched. Charting methods: Data will be extracted using a standardized form and synthesized narratively. …”
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Comparative analysis of upper body postural angles and their association with neck pain in car and motorcycle drivers by Aafreen Aafreen, Abdur Raheem Khan, Ashfaque Khan, Ausaf Ahmad, Monira I. Aldhahi, Weam Okab Alsalem, Mohammed M Alshehri, Almutasim Billa Moafa, Ahmed Ghazwani, Mohammad Abu Shaphe

“…Purpose: This study aimed to assess upper-body postural angles and neck pain among car drivers and motorcycle drivers separately, and to compare these outcomes between the two groups. Methods: This cross-sectional study comprised a total of 200 participants, with an equal distribution between car drivers (n = 100) and motorcycle drivers (n = 100). …”
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Dellon Decompression Using WALANT: A Safe and Effective Approach for Patients with Peripheral Artery Disease by Sofija Tusheva, Gordana Georgieva, Blagoja Srbov, Savetka Paljoskovska Jordanova, Katerina Jovanovska, Stefania Azmanova Mladenovska, Muamet Memeti, Darko Aleksovski, Biljana Mileska Krzhaloska, Sofija Pejkova

“…This study evaluates the safety, efficacy, and outcomes of WALANT for tarsal tunnel decompression in such patients. Methods: Between March 2022 and April 2024, 32 patients with diabetic neuropathy and PAD underwent Dellon decompression of the tarsal tunnel. …”
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Anesthesiologic management of pregnant women with SARS-COV-2 infection undergoing cesarean delivery by Antonio Coviello, Concetta Posillipo, Ludovica Golino, Carlo De Angelis, Elisabetta Gragnano, Gabriele Saccone, Marilena Ianniello, Gaetano Castellano, Annachiara Marra, Alfredo Maresca, Maria Vargas, Giuseppe Servillo

“…All pregnant women had pain visual analog scale (VAS) ≤3, and no pregnant women required rescue dose. …”
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Learning a Foreign Language in Older Adults Shapes the Functional Connectivity of Distinct Cerebellar Sub‐Regions With Cortical Areas Rich in CB1 Receptor Expression by Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L. Sensi, Stefano Delli Pizzi

“…We hypothesize that FLL primarily modulates the rs‐FC of the most “cognitive” cerebellar sub‐regions, such as the crus and the posterior lobules. Methods The rs‐FC pattern was analyzed in 27 participants who underwent a 4‐week FLL (n = 14) or a control (n = 13) protocol. …”
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Minimal dose CT for left ventricular ejection fraction and combination with chest-abdomen-pelvis CT by Martin Weber Kusk, Søren Hess, Oke Gerke, Lone Deibjerg Kristensen, Christina Stolzenburg Oxlund, Tina Elisabeth Ormstrup, Janus Mølgaard Christiansen, Shane J. Foley

“…Furthermore we assessed its potential for combining it with Chest-Abdomen-Pelvis CT (CAP-CT) for a one-stop examination. Materials &amp; methods: Eighty-two patients underwent helical low-dose CT. …”
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Assessing ResNeXt and RegNet Models for Diabetic Retinopathy Classification: A Comprehensive Comparative Study by Samara Acosta-Jiménez, Valeria Maeda-Gutiérrez, Carlos E. Galván-Tejada, Miguel M. Mendoza-Mendoza, Luis C. Reveles-Gómez, José M. Celaya-Padilla, Jorge I. Galván-Tejada, Antonio García-Domínguez

“…To enhance transparency, SHapley Additive exPlanations were employed to visualize the pixel-level contributions for each model’s predictions. …”
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Integrative Multi-Omics Analysis Reveals Critical Molecular Networks Linking Intestinal-System Diseases to Colorectal Cancer Progression by Shiliang Ji, Haoran Hu, Ruifang Zhu, Dongkai Guo, Yujing Liu, Yang Yang, Tian Li, Chen Zou, Yiguo Jiang, Guilai Liu

“…We employed a comprehensive bioinformatics approach to elucidate shared genetic signatures and pathways between CRC and ISDs. <b>Methods</b>: We systematically analyzed 12 microarray and RNA-seq datasets encompassing 989 samples across seven ISDs and CRC. …”
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Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning by Jiasi Zhang, Yichen Lei, Yaqin Wang, Wen Yu, Xiaoyan Zhao, Yongbing Zhu, Dedong Zhang, Siying Liu, Aiguo Liu

“…Elucidating these pathways is critical for advancing personalized treatments for MYCN‐driven NB. Methods We performed single‐cell transcriptomic analysis comparing NB samples with and without MYCN. …”
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Risk factors for biometry prediction error by Barrett Universal II intraocular lens formula in Chinese patients by Xu-Hao Chen, Ying Hong, Xiang-Han Ke, Si-Jia Song, Yu-Jie Cen, Chun Zhang

“…AIM: To investigate the influence of postoperative intraocular lens (IOL) positions on the accuracy of cataract surgery and examine the predictive factors of postoperative biometry prediction errors using the Barrett Universal II (BUII) IOL formula for calculation. METHODS: The prospective study included patients who had undergone cataract surgery performed by a single surgeon from June 2020 to April 2022. …”
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Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses by Maryam Rezazadeh, Shahla Danaei-Mehrabad, Nahideh Afshar Zakariya, Fatemeh Kazemi, Marziyeh Sadat Moslehian, Amin Tamadon, Reza Shirazi, Mahdi Mahdipour, Parvin Hakimi

“…This study aimed to identify new important molecular actors and clarify the molecular processes and pathways underlying EC metastasis. Methods: The GEOexplorer and R programming languages were used to analyze and visualize gene expression data from EC metastatic gene expression datasets, and differentially expressed genes (DEGs) and differentially expressed lncRNAs (DElncRNAs) were identified using bioinformatics with P-value thresholds of < 0.05, and |log2FC| > 1.5. …”
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