Non-invasive, non-enzymatic, non-serodiagnostic, and home-detecting paper-based “abnormal UA alarm” for early diagnosis of UA associated diseases by Qian Zhang, Hui’e Jiang, Zhijian Li, Lijuan Chen, Fengqian Yang, Jiamin Zhang, Bo Zhang, Xinhua Liu

“…Off-the-shelf UA detection methods clinically rely on uricase suffer from limitations such as high costs, longstanding result acquisition, circumscribed testing locations, rigorous expertise requirements, and difficulty in home-detecting due to serum testing systems. …”
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A pilot study to explore utility of electronic informed consent in a low- income setting; the case of a Controlled human infection study in Blantyre, Malawi [version 2; peer review... by Clara Ngoliwa, Joel Gondwe, Chikondi Chakwiya, Anthony E. Chirwa, Pemphero Liwonde, Evaristar Kudowa, Vitumbiko Nkhoma, Linda Chantunga, Modesta Reuben, Edward Mangani, Tiferanji Sochera, Neema Toto, Lumbani Makhaza, Dingase Dula, Stephen B. Gordon, Ben Morton, Tarsizio Chikaonda, Marc Y.R. Henrion, Edna Nsomba

“…Objectives We aimed to explore the utility of electronic consent (e-consent) in an ongoing human infection study in Blantyre, Malawi. Methods The approved paper consent forms were digitized using Open Data Kit (ODK). …”
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Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial by Cyrus Cooper, J-Y Reginster, R Chapurlat, C Christiansen, H Genant, N Bellamy, W Bensen, F Navarro, J Badurski, E Nasonov, X Chevalier, P N Sambrook

“…We describethe rationale and design of a randomised trial evaluating the efficacy and safety of strontium ranelate in knee osteoarthritis.Research design, methods, and results: This double-blind, placebo-controlled trial (98 centres, 18 countries) includes ambulatory Caucasian men and women aged ≥50 years with primary knee osteoarthritis of the medial tibiofemoralcompartment (Kellgren and Lawrence grade 2 or 3), joint space width (JSW) 2.5 to 5 mm, and knee pain on most days in the previous month (intensity ≥40 mm on a visual analogue scale). …”
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Effect of laser acupuncture on pain, range of motion, and function in patellofemoral pain syndrome: a randomised controlled trial by Nesma M. Allam, Hadeel Alsirhani, Maani Batel Alruwaili, Dalal Mabkhout Dosh, Huriyyah Mislat Alruwaili, Wessal Hisham Almazyad, Rokaia A. Toson, Doaa Ayoub Elimy, Doaa Ayoub Elimy, Mohamed El-Sherbiny, Ateya Megahed Ibrahim, Ateya Megahed Ibrahim, Hasnaa Ali Ebrahim, Nermine Nosseir, Mohamed A. Eladl, Zeinab A. Ali

“…Pain, knee range of motion (ROM), and function were evaluated at baseline and post-treatment using the visual analogue scale (VAS), goniometer, and Kujala score, respectively.ResultsNo significant differences were observed in the VAS, ROM, and Kujala scores for knee flexion and extension between the two groups before treatment (p > 0.05). …”
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Acupuncture for cancer-related insomnia: An evidence mapping by Zining Guo, Liying Wang, Yuting Wang, Wenhao Liu, Yi Zhao, Xiaorong Tang, Run Lin, Zhennan Wu, Shaoyang Cui, Nenggui Xu

“…The quality of studies was assessed using the Cochrane Risk of Bias 2.0 (RoB 2.0) tool, and key characteristics visualized EM. Finally, Acupoint data were systematically summarized. …”
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Clinical Features of Patients with Exfoliation Glaucoma Requiring Surgical Intervention by Hideyuki Nakano, Tetsuya Togano, Yuta Sakaue, Aki Suetaka, Ryu Iikawa, Rieko Nakano, Takeo Fukuchi

“…Retrospective study. Methods. The study included 46 eyes from 36 XFG patients, 85 eyes from 53 primary open-angle glaucoma (POAG) patients, and 54 eyes from 35 normal-tension glaucoma (NTG) patients. …”
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In what context and by which mechanisms can creative arts interventions improve wellbeing in older people? A realist review protocol [version 2; peer review: 2 approved] by Geoff Wong, Anne Ferrey, Alexandra Caulfield, Jeremy Leslie-Spinks, Nia Roberts, Trish Greenhalgh, Helle Mölsted Alvesson

“…Creative arts encompass a wide range of activities, including performing arts, visual arts, design and craft, literature, culture and digital and electronic arts. …”
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Analysis of the changes in corneal optical density following small incision lenticule extraction for myopia and related influencing factors by Yifan Du, Yu Di, Shan Yang, Ying Li

“…Purpose: To examine changes in corneal optical density (COD) following small incision lenticule extraction (SMILE) for myopia and the associated factors affecting COD. Methods: One hundred and ten eyes of 110 subjects who underwent SMILE were included in this study. …”
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Reducing Postoperative Neurological Complications in Uniportal Full-Endoscopic Lumbar Interbody Fusion: Efficacy of the GUARD Technique Combined With Delayed Ligamentum Flavectomy by Hao-Chun Chuang, Yu-Chia Hsu, Yuan-Fu Liu, Chao-Jui Chang, Yu-Meng Hsiao, Yi-Hung Huang, Keng-Chang Liu, Chien-Min Chen, Hyeun Sung Kim, Cheng-Li Lin

“…Patient-reported outcomes included the visual analogue scale (VAS) for leg and back pain, and Oswestry Disability Index. …”
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Arthroscopic Latarjet combined with remplissage and capsulolabral repair in the treatment of anterior shoulder instability—the quadruple effect. A prospective study of functional o... by Ayyappan V. Nair, DOrtho, DNB, MNAMS, Bharath Bharadwaj M S, MS Ortho, DNB(Ortho), Maythilisharan Rambhojan, MS Ortho, Sreejith Thampy J, MS Ortho, Aravind Rajan, MS Ortho, DNB ORTHO, Kiran V, MS Ortho, MRCS (Edinburgh), Prince Shanavas Khan, DOrtho, MS Ortho

“…To this effect, remplissage has had a proven track record in combination with Bankart repair. Methods: The functional and clinical outcomes of patients having undergone arthroscopic Latarjet with remplissage with a minimum of 2 years and secondarily, the external rotation was assessed postoperatively. …”
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Integration of Intraoperative Neurophysiological Monitoring into Laparoscopic Pelvic Nerve Decompression Surgery: A Novel Technique for Protecting Pelvic Nerves by Elif Cansu Gundogdu, Ahmet Kale, Metin Mercan, Vildan Yayla, Ugur Efe Ozcan, Taner Usta, Esra Keles

“…Background: This study aims to present a novel technique that integrates intraoperative neurophysiological monitoring (IONM) into laparoscopy for continuous monitoring of pelvic nerves at risk during surgery to ensure their protection. Methods: This is a prospective analysis of 10 consecutive patients receiving surgical treatment for proven diagnosis of lumbosacral plexus nerve entrapment. …”
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An explainable radiomics-based machine learning model for preoperative differentiation of parathyroid carcinoma and atypical tumors on ultrasound: a retrospective diagnostic study by Chunrui Liu, Wenxian Li, Baojie Wen, Haiyan Xue, Yidan Zhang, Shuping Wei, Jinxia Gong, Li Huang, Jian He, Jing Yao, Zhengyang Zhou

“…This study aimed to investigate the predictive performance of three radiomics-based machine learning models for the identification of PC/APT from solitary parathyroid lesions using ultrasound.MethodsThis retrospective diagnostic study analyzed 913 surgically-confirmed parathyroid neoplasms (mean age 54.2 ± 13.7 years; 694 females, 219 male) from Nanjing Drum Tower Hospital (n = 730) and Jinling Hospital (n = 183). …”
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Beyond the tray: analyzing hospital plate waste for economic and environmental sustainability by Mohamad G. Abiad, Maha Hoteit, Maha Hoteit, Maha Hoteit, Maroun Khattar, Ferial Fattouh, Dana Malli, Esraa Antar, Jana El Cheikh Mohammad, Nour Badereddine, Sami El Khatib, Sami El Khatib, Hussein F. Hassan

“…IntroductionHospital food services generate significant amounts of plate waste daily; thus, hospital waste has gained much attention in previous years.AimThis study aims to determine the magnitude of plate waste in Lebanese hospitals and highlight its economic and environmental repercussions.MethodsA descriptive cross-sectional study was conducted between April 2023 and September 2023 and involved 155 inpatients from cardiovascular, gastrointestinal, obstetrics-gynecology (OBGYN), and surgical wards of 16 hospitals across the Lebanese governorates. …”
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Alteration in ATR protein level does not account for the inherent radiosensitivity of HPV-positive head and neck squamous cell carcinoma by Sibylla Kohl, Florentine S.B. Subtil, Vanessa Climenti, Houmam Anees, Ann C. Parplys, Rita Engenhart-Cabillic, Sebastian Adeberg, Ekkehard Dikomey, Ulrike Theiß

“…If there is a contribution of ATR to the radiosensitivity of HPV-positive cells remains unclear, and this in-vitro study tested a functional involvement of ATR expression. Methods: The study was performed with six HPV-negative and six HPV-positive HNSCC cell lines. …”
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POLYMORPHISMS OF EXTRACELLULAR CONNECTIVE TISSUE REMODELING PROTEINASES AND <i>MMP2, MMP3, MMP9</i> GENES, AND NEOANGIGENESIS <i>VEGF</i> GENE IN RETINAL MICROANGIOPATHY IN THE PAT... by A. V. Shevchenko, V. F. Prokofiev, V. I. Konenkov, V. V. Klimontov, N. V. Tyan, D. V. Chernykh, A. N. Trunov, V. V. Chernykh

“…The genetic typing was carried out by restriction fragment length polymorphism and TaqMan methods.The analysis of complex genotypes at the five polymorphic positions has revealed some significant findings in positive and negatively incorporated complexes. …”
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Exome-wide genetic risk score (ExGRS) to predict high myopia across multi-ancestry populations by Jian Yuan, Ruowen Qiu, Yuhan Wang, Zhen Ji Chen, Haojun Sun, Wei Dai, Yinghao Yao, Ran Zhuo, Kai Li, Shilai Xing, Myopia Associated Genetics and Intervention Consortium, Xiaoguang Yu, Liya Qiao, Jia Qu, Jianzhong Su

“…Employing a genetic risk score (GRS) is useful for capturing genetic susceptibility to HM. Methods This study assesses the effectiveness of these strategies via incorporating rare variations into the GRS assessment. …”
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Closed trans-intersphincteric fistulotomy: a new modified sphincter-sparing technique for high transsphincteric anal fistula by Bo Chen, Yueting Wang, Zubing Mei, Chang Mao, Yicheng Liu, Wenjun Zhao, Yingying Li, Qianqian Ye, Jin Xu, Qingming Wang, Qingming Wang

“…This study evaluated the clinical efficacy of a novel sphincter-sparing technique for treating high transsphincteric anal fistula (HTAF).MethodsThis prospective study included 55 patients with HTAF who underwent closed trans-intersphincteric fistulotomy (CTiF) between July 2021 and April 2022 at our institution. …”
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Scleral Buckling for Primary Retinal Detachment: Outcomes of Scleral Tunnels versus Scleral Sutures by Matthew R. Starr, Edwin H. Ryan, Anthony Obeid, Claire Ryan, Xinxiao Gao, Malika L. Madhava, Sean M. Maloney, Adam Z. Adika, Krishi V. Peddada, Kareem Sioufi, Luv G. Patel, Michael J. Ammar, Nora J. Forbes, Antonio Capone Jr., Geoffrey G. Emerson, Daniel P. Joseph, Dean Eliott, Carl D. Regillo, Jason Hsu, Omesh P. Gupta, Yoshihiro Yonekawa, for the Primary Retinal Detachment Outcomes (PRO) Study Group

“…Pre- and postoperative variables were evaluated including visual acuity, anatomic success, and postoperative strabismus. …”
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Enhancing Pain Management and Psychological Recovery in Earthquake Victims: The Role of Continuous Regional Analgesic Techniques Assessed by QoR-15 by Ergun Mendes, Ozal Adiyeke, Onur Sarban, Melih Civan, Okyar Altas, Alperen Korucu, Funda Gumus Ozcan, Gozen Oksuz

“…Baseline, 24 h, 72 h QoR-15 (Quality of Recovery-15), and VAS (Visual Analog Scala) scores were compared for changes over time. …”
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Biportal endoscopic lumbar discectomy surgery in patients with cauda equina syndrome caused by lumbar herniated intervertebral disc: a retrospective multi-center cohort study by Sang-Min Park, Ho-Jin Lee, Hyun-Jin Park, Ki-Han You, Jong-Hun Jung, Samuel K. Cho, Ho-Joong Kim, Jin S. Yeom

“…This study evaluates the efficacy of biportal endoscopic (BE) lumbar discectomy in treating CES caused by lumbar herniated intervertebral discs. Methods This retrospective case series includes 32 CES patients treated with BE lumbar discectomy from March 2017 to July 2022. …”
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