A new technique of inverted internal limiting membrane flap formation in a surgical treatment for large idiopathic macular holes by I. A. Belyi, A. V. Tereshchenko, D. O. Shkvorchenko, E. V. Erokhina, N. M. Shilov

“…To develop a surgical treatment for large idiopathic macular holes using a new technique of internal limiting membrane fragment formation to close the macular hole.Material and methods. We observed 19 patients, from 56 to 71 years old (average age was 63,8±5,3 years old) with idiopathic macular holes (IMH) stage III according to J. …”
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ASSESSMENT OF THE QUALITY OF LIFE OF PATIENTS WITH THE JUVENILE IDIOPATHIC ARTHRITIS TREATED BY THE ETANERCEPT by A. N. Fetisova, E. I. Alexeeva, T. M. Bzarova, S. I. Valieva, V. V. Chernikov, I. V. Vinyarskaya, R. V. Denisova, K. B. Isaeva, E. G. Chistyakova, Т. V. Sleptsova, N. I. Taibulatov

“…Aim: To assess the influence of the genetically engineered biologic drug etanercept on the quality of life of patients with juvenile idiopathic arthritis (JIA). Patients and methods: The research included 85 children with poly-and oligoarticular variant of the JIA at the age of 5 (2; 17) years. …”
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Role of hypoxia-related genes and immune infiltration in intervertebral disc degeneration: molecular mechanisms and diagnostic potential by Kai Zhou, Jiaxiang Zhou, XianJin Luo, Yan Chen, Jian Ao, Wei Wu, Bo Yang, Zhongyuan He

“…ObjectiveTo investigate the role of hypoxia-related genes and immune infiltration in intervertebral disc degeneration (IDD) to identify molecular mechanisms and potential therapeutic targets.MethodsUsing GEO data, IDD-related gene expression datasets were analyzed for hypoxia-related differentially expressed genes (HRDEGs). …”
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Detection of pulmonary nodules: a clinical study protocol to compare ultra-low dose chest CT and standard low-dose CT using ASIR-V by Marie Ludwig, Emilie Chipon, Julien Cohen, Emilie Reymond, Maud Medici, Anthony Cole, Alexandre Moreau Gaudry, Gilbert Ferretti

“…The aim of this study is to demonstrate that an ultra-low dose (ULD) chest CT protocol, using recently introduced hybrid iterative reconstruction (ASiR-V, GE medical Healthcare, Milwaukee, Wisconsin, USA), is as performant as a standard ‘low dose’ (LD) CT to detect non-calcified lung nodules ≥4 mm.Methods and analysis The total number of patients to include is 150. …”
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Bridging the gap: clinical translation of adipose-derived stem cells - a scoping review of clinical trials by Hankun Su, Hoksan Chau, Qilin Li, Fen Xiao, Yuanyuan Sun, Jingjing Chen, Yayi He, Jinyao Ning, Qin Hu, Yujie Xiao, Caiwen Li, Bixia Huang, Jing Zhao, Yanping Li, Hui Li

“…Key gaps included protocol heterogeneity (e.g., isolation methods, cryopreservation variability), regulatory fragmentation, limited long-term follow-up, and inconsistent clinical outcomes, particularly in neurology. …”
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Popliteal sciatic nerve block versus intrathecal anesthesia for Achilles tendon rupture repair surgery: a mono-centric retrospective comparative study by Gao Si, Gao Si, Liwei Wang, Minzhi Deng, Yihan Sun, Yuan Cao, Yuan Cao, Jixing Fan, Tengjiao Zhu, Yun Tian, Yang Lv, Changyi Wu

“…Patients were divided into two groups based on the different anesthesia methods they received: the popliteal sciatic nerve block group (BG) and the spinal anesthesia group (SAG). …”
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Arts-based approaches to promoting health in sub-Saharan Africa: a scoping review by Stuart Gray, Amelia Crampin, Cindy M Gray, Christopher Bunn, Chisomo Kalinga, Otiyela Mtema, Sharifa Abdulla, Angel Dillip, John Lwanda, Sally M Mtenga, Jo Sharp, Zoë Strachan, Jason Gill, Hazel Namadingo, Mia Perry, Helen Todd

“…To date, no review has sought to map the locations, health issues, art forms and methods documented by researchers using arts-based approaches in SSA.Methods Using scoping review methodology, 11 databases spanning biomedicine, arts and humanities and social sciences were searched. …”
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Agreement between Gonioscopic Examination and Swept Source Fourier Domain Anterior Segment Optical Coherence Tomography Imaging by Mohammed Rigi, Nicholas P. Bell, David A. Lee, Laura A. Baker, Alice Z. Chuang, Donna Nguyen, Vandana R. Minnal, Robert M. Feldman, Lauren S. Blieden

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PEMOCS: effects of a concept-guided, PErsonalized, MOtor-Cognitive exergame training on cognitive functions and gait in chronic Stroke—a randomized, controlled trial by S. K. Huber, S. K. Huber, R. H. Knols, R. H. Knols, J. P. O. Held, J. P. O. Held, M. Betschart, M. Betschart, S. Gartmann, S. Gartmann, N. Nauer, N. Nauer, E. D. de Bruin, E. D. de Bruin, E. D. de Bruin

“…Therefore, this study investigates the effects of a concept-guided, personalized, motor-cognitive exergame training on cognitive functions and gait in chronic stroke survivors.MethodsIn this single-blind, randomized, controlled trial, stroke survivors (at least six-months post-stroke and able to perform step-based exergaming) were allocated either to the intervention (usual care + concept-guided, personalized, motor-cognitive exergame training) or the control group (usual care only). …”
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LEVELS OF ANGIOGENESIS-REGULATORY CHEMOKINES IN THE SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS by D. A. Zhebrun, A. L. Maslyansky, A. G. Titov, A. P. Patrukhin, A. A. Kostareva, I. S. Goltseva, N. A. Arsentyeva, N. E. Lyubimova, A. A. Totolyan

“…Objective: to perform a comparative analysis of the levels of a number of CXC, CC, and CX3C chemokines in the SF of patients with RA, osteoarthritis (OA), and joint injuries. Subjects and methods. The multiplex analysis using xMAP technology (Luminex, USA) was used to analyze levels of CXC, CC, and CX3C chemokines in SF and serum of patients with RA (n = 20), OA (n = 9) and controls (n = 9). …”
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Thalamic functional dysconnectivity in patients with left-hemisphere chronic capsular and pontine stroke by Jun Guo, Jun Guo, Hongchuan Zhang, Hongchuan Zhang, Jingchun Liu, Caihong Wang, Chen Cao, Jingliang Cheng, Chunshui Yu, Wen Qin

“…However, the differential involvements of thalamic functional connectivity in chronic capsular and pontine stroke are still unknown.MethodsThe research recruited 66 left-lesion chronic stroke patients, including 46 capsular strokes (CS) and 20 pontine stroke (PS) patients, and 67 normal controls (NC). …”
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Could cough hypersensitivity symptom profile differentiate phenotypes of chronic cough? by Mi-Yeong Kim, Ha-Kyeong Won, Ji-Yoon Oh, Ji-Hyang Lee, Eun-Jung Jo, Sung-Yoon Kang, Ji-Ho Lee, Seung-Eun Lee, Noeul Kang, Young-Chan Kim, Hwa Young Lee, Jin An, Youngsang Yoo, Ji-Su Shim, So-Young Park, Han-Ki Park, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung-Jae Lee, Surinder S. Birring, Woo-Jung Song

“…This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC). Methods Patients with chronic cough from the Korean Chronic Cough Registry were prospectively evaluated over 6 months. …”
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Millettia aboensis leaves extract as eco-friendly corrosion inhibitor for mild steel in acidizing solution: From experimental to molecular level prediction by Fidelis E. Abeng, Benedict I. Ita, Magdalene E. Ikpi, Vitalis I. Chukwuike, Alexander I. Ikeuba, Moses M. Edim, Maduabuchi A. Chidiebere, Abhinay Thakur, Valentine C. Anadebe

“…The anti-corrosive effectiveness of Millettia aboensis leaves extract (MALE) has been assessed in this study using several methods, such as electrochemical measurements, X-ray Photoelectron spectroscopy and scanning electron microscopy on mild steel in acidic solution. …”
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AN OPEN-LABEL MULTICENTER OBSERVATIONAL STUDY OF THE EFFICACY, TOLERABILITY, AND SAFETY OF THE NONSTEROIDAL ANTI-INFLAMMATORY DRUG AMTOLMETIN GUACIL IN PATIENTS WITH KNEE OSTEOARTH... by E. S. Tsvetkova, L. N. Denisov, A. N. Otteva, A. L. Dubikov, S. P. Yakupova, O. N. Ivanova, N. I. Korshunov, A. R. Vaisberg, R. A. Abyshev, A. V. Tartynov, E. L. Nasonov

“…Reddy's Laboratories Ltd, India) versus previous therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with knee osteoarthritis (OA) and signs of dyspepsia.Subjects and methods. The open-label observational study included 220 patients aged 30–65 years who suffered from knee OA and intense pain during NSAID intake and had symptoms of dyspepsia in the absence of contraindications to the use of AMG. …”
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Adalimumab Accounts for Long-Term Control of Noninfectious Uveitis Also in the Absence of Concomitant DMARD Treatment: A Multicenter Retrospective Study by Alice Bitossi, Alessandra Bettiol, Elena Silvestri, Gerardo Di Scala, Daniela Bacherini, Giuseppe Lopalco, Vincenzo Venerito, Florenzo Iannone, Antonio Vitale, Gian Marco Tosi, Domenico Prisco, Stanislao Rizzo, Claudia Fabiani, Luca Cantarini, Gianni Virgili, Lorenzo Vannozzi, Giacomo Emmi

“…This study was aimed at assessing the long-term ocular control of adalimumab (ADA) in a large real-world population with noninfectious primary or secondary uveitis, focusing on the steroid-sparing effect and on disease-modifying antirheumatic drug (DMARD) cotreatment. Methods. In this retrospective, multicenter study, the efficacy of ADA was evaluated in terms of ocular control, changes in best-corrected visual acuity (BCVA), corticosteroid-sparing effect, and drug retention rate, overall and stratified according to DMARD cotreatment. …”
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Association of cervical artery stenosis with common cerebral microvascular lesions and coronary artery calcifications by Chiheb Louizi, Eya Khadhraoui, Eya Khadhraoui, Joachim Lotz, Joachim Lotz, Joachim Lotz, Daniel Behme, Daniel Behme, Erelle Fuchs, Johannes T. Kowallick, Johannes T. Kowallick, Sebastian J. Müller, Sebastian J. Müller

“…CT scans were assessed for coronary artery disease using a modified overall visual assessment. Fazekas scores were used to evaluate the MRI for white matter changes. …”
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Exploring the impact of a daily sport uniform policy in primary schools: a qualitative study with students and teachers by Carly Gardner, Carly Gardner, Carly Gardner, Carly Gardner, Cassandra Lane, Cassandra Lane, Cassandra Lane, Cassandra Lane, Alix Hall, Alix Hall, Alix Hall, Alix Hall, Nicole McCarthy, Nicole McCarthy, Nicole McCarthy, Nicole McCarthy, Emma Pollock, Emma Pollock, Emma Pollock, Emma Pollock, Rachel Sutherland, Rachel Sutherland, Rachel Sutherland, Rachel Sutherland, Luke Wolfenden, Luke Wolfenden, Luke Wolfenden, Luke Wolfenden, Nicole Nathan, Nicole Nathan, Nicole Nathan, Nicole Nathan

“…First, daily sport uniform wear was highly accepted, due to their visual appeal, simplicity and cost-savings relative to formal uniforms. …”
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Efficacy of combining posterior scleral contraction and intravitreal C3F8 injection in high myopia with macular hole retinal detachment by Si Chen, Jie Ye, Qin-Tuo Pan, Fang Huang, Lin-Yan Zheng, Hui-Fang Ye, Yan-Feng Su, Yan Li, Shuang-Qian Zhu

“…Outcome measures included best-corrected visual acuity (BCVA), AL, optical coherence tomography (OCT) findings, and adverse events. …”
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Hybrid Deep Learning for Survival Prediction in Brain Metastases Using Multimodal MRI and Clinical Data by Cristian Constantin Volovăț, Călin Gheorghe Buzea, Diana-Ioana Boboc, Mădălina-Raluca Ostafe, Maricel Agop, Lăcrămioara Ochiuz, Ștefan Lucian Burlea, Dragoș Ioan Rusu, Laurențiu Bujor, Dragoș Teodor Iancu, Simona Ruxandra Volovăț

“…<b>Background:</b> Survival prediction in patients with brain metastases remains a major clinical challenge, where timely and individualized prognostic estimates are critical for guiding treatment strategies and patient counseling. <b>Methods:</b> We propose a novel hybrid deep learning framework that integrates volumetric MRI-derived imaging biomarkers with structured clinical and demographic data to predict overall survival time. …”
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Silver diamine fluoride alters microbial communities in subsurface dentinWhy Is This Important? by Rosalyn M. Sulyanto, DMD, MS, Clifford J. Beall, MS, PhD, Martin T. Berger, DMD, Christopher P. Goodell, DMD, Stephanie Koo, DMD, Fiorella Candamo, DMD, John R. Dickson, MD, PhD, Misun Kang, PhD, Sunita P. Ho, PhD, Man Wai Ng, DDS, MPH, Shahr B. Hashmi, BS, Eugene J. Leys, PhD, Ann L. Griffen, MS, DDS

“…Results: Viability testing of surface biofilm from carious lesions with or without SDF treatment visualized by confocal laser scanning microscopy revealed no change in microbial viability several weeks after SDF treatment. …”
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