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19061
Neurocognition as a major predictor of 8-week response to antipsychotics for drug-naïve first-episode schizophrenia using machine learning
Published 2025-07-01“…However, it is unclear whether neurocognitive dysfunction can predict the efficacy of antipsychotics for first-episode schizophrenia (FES). Machine learning methods provide a relatively unbiased approach when evaluating heterogeneous data, especially when building multifactor prediction models. …”
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19062
Machine learning-based prediction of the necessity for the surgical treatment of distal radius fractures
Published 2025-04-01“…This study aimed to develop a machine learning (ML) model that determines the need for surgical treatment in patients with DRFs using a ML model that incorporates various clinical data concatenated with plain radiographs in the anteroposterior and lateral views. Methods Radiographic and clinical data from 1,139 patients were collected and used to train the ML models. …”
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19063
Periorbital necrotizing fasciitis: the Manchester experience
Published 2025-04-01“…The median (IQR) final best recorded visual acuity (BRVA) was 2.0 (0.23–3) logMAR. Three patients developed orbital compartment syndrome; 2 of these had a final BRVA of no perception of light (NPL). …”
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19064
The effect of cognitive function heterogeneity on depression risk in older adults: a stratified analysis based on functional status
Published 2025-08-01“…This study aimed to reveal the heterogeneity of cognitive functioning in older adults under different physical functional states through latent profile analysis (LPA) and to explore the patterns associated with depressive symptoms.MethodsBased on the China Health and Retirement Longitudinal Study (CHARLS) 2020 data, 4,158 older adults ≥60 years old were included, and the subtypes of cognitive functions (immediate memory, delayed memory, calculative ability, orientation, and visual construction) were classified by LPA. …”
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19065
Variasi Panjang Fragmen Gen ND3 Burung Famili Ploceidae Endemik Pulau Jawa (The Length Variation of ND3Gen Fragmen of Java’s Endemic Ploceidae Family’s Birds)
Published 2009-03-01“…The research aimed to knew the length fragmen of ND3 DNAmt Gen and genetic variation among species of Ploceidae family’s birds. 11 species were observe for morphology’s characteristic than blood sample were collected for DNA isolation with Dixit methode. ND3 gen were amplificated by DNA isolated with PCR used H11151 and L10755 primer. …”
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19066
The Association of Social Determinants of Health and Patient-Reported Outcomes In Patients with Surgical Treatment of Osteochondral Lesion of the Talus
Published 2024-12-01“…The effect of social determinants of health (SDOH) on treatment outcomes of this patient population has rarely been investigated to date. Methods: Patients with OLT who were 18 years of age and older and underwent operative treatment, with at least one patient-reported outcome and SDOH data available, were included. …”
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19067
Pilot Programme for Keratoconus Screening and Management in Adolescents with Down Syndrome
Published 2025-03-01“…<b>Background/Objectives</b>: To screen a group of adolescents with Down Syndrome (Trisomy 21) for keratoconus and assess the feasibility of setting up a national screening service. <b>Methods</b>: Twenty-seven patients with Down Syndrome between 9 and 18 years of age attended our pilot keratoconus screening clinic. …”
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19068
Metformin for knee osteoarthritis with obesity: study protocol for a randomised, double-blind, placebo-controlled trial
Published 2023-12-01“…The aim of this randomised, double-blind, placebo-controlled trial is to determine whether metformin reduces knee pain over 6 months in individuals with symptomatic knee OA who are overweight or obese.Methods and analysis One hundred and two participants with symptomatic knee OA and overweight or obesity will be recruited from the community in Melbourne, Australia, and randomly allocated in a 1:1 ratio to receive either metformin 2 g or identical placebo daily for 6 months. …”
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19069
Comparison of short-term effectiveness between unilateral biportal endoscopic and MED-assisted transforaminal lumbar interbody fusion for mild single-segment lumbar spondylolisthes...
Published 2025-07-01“…Abstract Objectives The purpose of this study was to compare the short-term clinical efficacy of unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) versus minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) with microendoscopic discectomy (MED) for lumbar spondylolisthesis. Methods The patients were divided into MIS-TLIF group and UBE-TLIF group according to the surgical procedures. …”
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19070
Retinal structure and related factors in 8-year-old Japanese children: The Yamanashi adjunct study of the Japan Environment and Children's Study.
Published 2025-01-01“…The visual acuity, spherical equivalent (SE), axial length (AL), and body height of the participants were measured. …”
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19071
Subcutaneous sumatriptan for the treatment of postcraniotomy pain (SUPS trial): protocol for a randomised double-blinded placebo controlled trial
Published 2019-08-01“…Our null hypothesis states that sumatriptan is not different to placebo in addition to usual intravenous opioids, for the treatment of acute postcraniotomy pain.Methods and analysis This is a prospective single-centre randomised double-blinded placebo-controlled phase III clinical trial comparing subcutaneous sumatriptan injection in the recovery area with placebo for the treatment of postcraniotomy pain. …”
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19072
Cardiac Magnetic Resonance Imaging Markers in Idiopathic Inflammatory Myopathy – A Prospective Observational Study
Published 2025-05-01“…Cardiac symptoms were reported by 45.2% of the cases, while 48.3% had an MDAAT cardiac Visual Analog Scale (VAS) score of ≥1, indicating potential cardiac involvement. …”
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19073
Comparison of Guided Exercise and Self-Paced Exercise After Lumbar Spine Surgery: A Randomized Controlled Trial
Published 2025-07-01“…Clinical outcomes were assessed using the visual analog scale (VAS) for pain and EuroQol-5 Dimensions 5-Level version (EQ-5D-5L). …”
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19074
RELATIONSHIP BETWEEN PERIODONTAL DISEASES AND MENTAL HEALTH: A NARRATIVE REVIEW
Published 2025-05-01“…Ultimately, 56 records were excluded after reading full-text, and the process is visually summarized in a PRISMA flowchart. Results. …”
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19075
The Relationship Between Manual Dexterity and Toothbrushing Efficiency in Preschool Children: A Crossover Study
Published 2024-12-01“…Aim: The aim of this study was to evaluate the relationship between oral hygiene (OH) efficiency and manual dexterity skills in Spanish five-year-old children using two fine motor tests. Methods: A cross-sectional study with a pre–post evaluation was designed. …”
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19076
Short-Term Outcomes of First Metatarsophalangeal Arthroplasty Using the Silktoe Double-Stemmed Silicone Implant
Published 2025-05-01“…The American Orthopaedic Foot and Ankle Society-Hallux Metatarsophalangeal-Interphalangeal Scale (AOFAS-HMI) score was 94.6 ± 7.6 (median, 100; range, 70–100) and the Visual Analogue Scale (VAS) score was 0.4 ± 0.80 (median, 0; range, 0–3.5) at the final follow-up. …”
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19077
hERGAT: predicting hERG blockers using graph attention mechanism through atom- and molecule-level interaction analyses
Published 2025-01-01“…Many in silico models have been developed to predict hERG blockers, which can efficiently save time and resources. However, previous methods have found it hard to achieve high performance and to interpret the predictive results. …”
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19078
Social media use and negative body image perception in Saudi Arabian women
Published 2025-05-01“…BackgroundSocial media has become deeply embedded in daily life, particularly among females who spend significant time on visual-based platforms such as Snapchat, and Instagram. …”
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19079
DIACEREIN AS THE DRUG OF CHOICE IN THE THERAPY OF KNEE OSTEOARTHRITIS WITH SECONDARY RECURRENT SYNOVITIS
Published 2016-02-01“…Objective: to evaluate the efficacy and tolerability of diacerein in the therapy of primary knee osteoarthritis (OA) with secondary recurrent synovitis.Subjects and methods. The 3-month open-label randomized controlled trial enrolled 133 patients with OA. …”
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19080
Effects of a combined aerobic and core stabilization exercise training program on functional capacity, pain, and health-related quality of life in hemodialysis and kidney transplan...
Published 2024-12-01“…Functional capacity was measured using the 6-min walk test, pain was measured using the visual analog scale, and health-related quality of life was measured using the Kidney Disease Quality of Life–Short Form 12 questionnaire. …”
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