Comparative Analysis of Sutured and Sutureless 25G Pars Plana Vitrectomy: Impact on Surgically Induced Astigmatism and Hypotony by Ebubekir Durmuş, Ahmad Kunbaz, Gözde Derin Şengün, Veysel Aykut, Fehim Esen, Halit Oğuz

“…This study compares outcomes between sutureless and sutured 25G pars plana vitrectomy (PPV) and highlights sutures’ significance in TSV. Methods: Fifty-four eyes underwent 25G PPV, divided into sutureless and sutured groups based on sclerotomy closure methods. …”
Get full text

The Efficacy of Transversus Abdominis Plane Block for Analgesia in Comparison with Local Anesthetic Wound Infiltration Post-Cesarean Section: A Randomized Comparative Double-Blinde... by Mona Saad Salman, Ahmed Shaker, Heba Rady Elbassyouny, Ramy Mohamad Elnaggar, Mohamed Raslan, Ali Elsayed Khayal, Safaa Ibrahim Mahmoud

“…Transversus abdominis plane (TAP) block and local anesthetic wound infiltration (LWI) are commonly used techniques for post-cesarean analgesia. While both methods have shown efficacy, their comparative effectiveness remains debated. …”
Get full text

Therapeutic effect of miR-30b-5p-loaded lentivirus on experimental autoimmune uveitis via inhibiting Notch signaling activation by Xuewei Yin, Huixia Wei, Lijie Guo, Bin Liu, Yuan Peng, Mengxian Zhou, Yan Qiu, Ruyi Qu, Yane Gao, Qiuxin Wu, Wenjun Jiang, Hongsheng Bi, Dadong Guo

“…Abstract Background Uveitis is a common recurrent autoimmune disease that seriously endangers the visual health of patients. MicroRNAs (miRNAs) are closely related to a series of autoimmune diseases. …”
Get full text

Mapping the key players in Kawasaki disease; role of inflammatory genes and protein-protein interactions by Wael Hafez, Feras Al-Obeidat, Asrar Rashid, Afsheen Raza, Nouran Hamza, Nesma Ahmed, Marwa M. Abdeljawad, Raziya Kadwa, Abdelhameed Elmesery, Muneir Gador, Dina Khair, Gihan Zina, fatema Abdulaal, Mina Wassef Girgiss, Maha Abdelhadi, Ahmed Abdelrahman, Mahmad Anwar Ibrahim, Mohamed El Sherbiny

“…Objective: This study aimed to identify the genetic patterns and molecular mechanisms associated with KD using a comprehensive gene expression analysis. Methods: RNA sequencing and microarray genomic datasets were retrieved from the NCBI Gene Expression Omnibus (GEO). …”
Get full text

Assessing the neurological impact of vitamin B12 deficiency among the population of Riyadh, Saudi Arabia by Khalid A. Bin Abdulrahman, Abdulelah F. Alshehri, Faisal Marzouq Almutairi, Faisal Ali Almahyawi, Rayan Saleh Alzahrani, Osama Thamer Al-Ahmari, Khalid Alshammari, Turki Ahmed Aljuhani, Yazeed Yahya Alkadi, Mohammed Atiah Alisi

“…BackgroundVitamin B12 (cobalamin) deficiency can cause anemia, peripheral neuropathy, visual impairment and irreversible neurological damage. …”
Get full text

Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort... by Adrián Borja-Flores, Salvador I. Macías-Hernández, Gabriela Hernández-Molina, Andric Perez-Ortiz, Eloy Reyes-Martínez, José Belzazar-Castillo de la Torre, Laura Ávila-Jiménez, María Cristina Vázquez-Bello, Marco Antonio León-Mazón, Janette Furuzawa-Carballeda, Gonzalo Torres-Villalobos, Fernanda Romero-Hernández, Cidronio Albavera-Hernández, Jesús Pérez-Correa, Hilda A. Castro-Rocha

“…The aim was to evaluate the effect of intra-articular injections (IAIs) of polymerized-collagen among patients with symptomatic knee osteoarthritis (OA) in delaying or preventing joint replacement surgery. Patients and Methods. This was a cohort study of 309 patients with knee OA. …”
Get full text

P300 event-related potentials as diagnostic biomarkers for attention deficit hyperactivity disorder in children by Chuanxue Tan, Chuanxue Tan, Huimin Zhou, Anqi Zheng, Miao Yang, Chunyang Li, Ting Yang, Tingyu Li, Jie Zhang

“…Using a visual Oddball paradigm, P300 parameters were recorded at Fz, Cz, and Pz zones. …”
Get full text

Comparative analysis of endophytic bacterial localization and microbiome diversity in plant varieties under varied growth conditions through microscopic imaging and sequencing tech... by Mohd Shadab, Mohd Shadab, Suman Kumar Samanta, Jilmil Baruah, Sujata Deka, Garima Raj, Narayan C. Talukdar, Narayan C. Talukdar

“…Pratap using SYTO9 (S9) and Propidium Iodide (PI) staining.MethodologyConfocal Laser Scanning Microscopy (CLSM) was used to visualized bacterial localization, MitoTracker Deep Red (MDR) was used to confirm non- overlapping mitochondrial staining. …”
Get full text

Real-time intestinal perfusion assessment for anastomotic site selection using laser speckle contrast imaging: Verification in a porcine model by Danique J.I. Heuvelings, Mahdi Al-Taher, Joost Calon, Manish Chand, Laurents P.S. Stassen, Tim Lubbers, Kevin P. Wevers, Luigi Boni, Nicole D. Bouvy, Wido Heeman

“…Therefore, we explored the efficacy and feasibility of a new laser speckle contrast imaging system to assess real-time intestinal perfusion. Methods: Three gradually perfused porcine small bowel loops were created, and five senior surgeons were asked to assess the perfusion differences based on laser speckle contrast images using PerfusiX-Imaging®. …”
Get full text

Cognitive Correlates of Borderline Personality Disorder Features in Youth with Bipolar Spectrum Disorders and Bipolar Offspring by Alessio Simonetti, Sherin Kurian, Evelina Bernardi, Antonio Restaino, Francesca Bardi, Claudia Calderoni, Gabriele Sani, Jair C. Soares, Kirti Saxena

“…<b>Objectives:</b> This study aimed to investigate the association between BPD features and cognitive impairments in youth with BD and BD-OFF. <b>Methods:</b> Thirty-nine participants (7–17 years) with BD, 18 BD-OFF, and 50 healthy controls (HCs) were recruited. …”
Get full text

Research on neurotrophic factor for glaucoma: a worldwide bibliometric analysis by Sahilah Ermawati, Winastari Yarhanim Triniputri, Muhana Fawwazy Ilyas, Syahnaz Adilla, Shafira Nur Hanifa, Azka Auliarahman

“…These articles were subsequently analyzed and visualized using Google Sheets, Biblioshiny 3.1, and VosViewer 1.6.18. …”
Get full text

Regional homogeneity patterns reveal the genetic and neurobiological basis of State-Trait Anxiety by Yuanhao Li, Su Yan, Jia Li, Yuanyuan Qin, Li Li, Nanxi Shen, Yan Xie, Dong Liu, Jicheng Fang, Tian Tian, Wenzhen Zhu

“…However, the genetic and neurobiological basis of anxiety-related functional changes remain largely unknown. Methods Participants aged 18–30 from the community underwent resting-state fMRI and were assessed with the State-Trait Anxiety Inventory. …”
Get full text

Rapid Therapeutic Drug Monitoring of Voriconazole Based on High-Performance Liquid Chromatography: A Single-Center Pilot Study in Outpatients by Satoru Morikawa, Yusuke Yagi, Moemi Okazaki, Narika Yanagisawa, Tomoaki Ishida, Kohei Jobu, Takumi Maruyama, Takahiro Kato, Miyuki Matsushita, Yu Arakawa, Yuka Yamagishi, Yukihiro Hamada

“…This study aimed to evaluate the clinical utility of rapid therapeutic drug monitoring (TDM) for VRCZ using high-performance liquid chromatography with ultraviolet detection (HPLC-UV) compared to conventional outsourced liquid chromatography–tandem mass spectrometry (LC-MS/MS) testing in outpatient care. <b>Methods</b>: VRCZ blood concentrations were measured using HPLC-UV and LC-MS/MS. …”
Get full text

Evaluating multimodal physiological signals for fear detection: relative utility of pupillometry, heart rate, and EEG by Yuki Ebato, Tomita Saki, Isshu Wakita, Ayumu Ueno, Tomoaki Ishibashi, Tetsuya Takahashi, Tetsuya Takahashi, Tetsuya Takahashi, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa

“…In this context, we aimed to evaluate the practical effectiveness and limitations of a multimodal approach that combines pupil dynamics and heart rate—indirect indicators of deep brain activity—with EEG, a temporally precise but spatially limited measure of cortical responses.MethodsWe simultaneously recorded EEG, pupillometry, and heart rate in 40 healthy male participants exposed to fear-inducing and neutral visual stimuli, while also assessing their psychological states.ResultsFear-inducing stimuli elicited distinct physiological responses, including increased occipital theta power, pupil dilation, and decreased heart rate. …”
Get full text

Bibliometric mapping of diabetes mellitus and sarcopenia research: hotspots and emerging trends by Min Wang, Qiyang Zhou, Xinyu Guo, Xiaolong Cui, Zhongquan Tang, Ting Ou, Xiaomin Zhao, Chen Liang, Peiyu Xu, Xinyu Dai, Jingqing Yao, Guozhong Ji, Yuntao Li

“…This study pioneers a bibliometric analysis to systematically investigate their association, aiming to map the knowledge structure, evolutionary trajectories, current foci, and emerging frontiers within this area.MethodsWe retrieved 2,773 publications from the Web of Science Core Collection from inception until December 26, 2024, and visual analyses were conducted using CiteSpace, VOSviewer, R, and Microsoft Excel. …”
Get full text

A comparative study on efficacy and safety of modified partial stapled hemorrhoidopexy versus conventional hemorrhoidectomy: a prospective randomized controlled trial by Tae Gyu Kim, Chul Seung Lee, Dong Geun Lee, Choon Sik Chung, Seung Han Kim, Sang Hwa Yu, Jeong Eun Lee, Gwan Cheol Lee, Dong Woo Kang, Jeong Sub Kim, Gyu Young Jeong

“…This study aimed to introduce a modified PSH (mPSH) and compare its clinical efficacy and safety with those of CH. Methods A prospective randomized controlled trial was conducted. …”
Get full text

Transthoracic echocardiography during prone position ventilation: Lessons from the COVID‐19 pandemic by Edgar García‐Cruz, Daniel Manzur‐Sandoval, Rodrigo Gopar‐Nieto, Adriana L. Murillo‐Ochoa, Gabriela Bejarano‐Alva, Gustavo Rojas‐Velasco, Rolando J. Álvarez‐Álvarez, Francisco Baranda‐Tovar

“…Results Adequate image acquisition of the left ventricle was possible in all cases; we were not able to visualize the right ventricular free wall only in 1 patient. …”
Get full text

High-flow nasal cannula oxygen therapy versus non-invasive ventilation in healthy respiratory physicians: a non-randomized study by Hong Ye, Dandan Xiang, Xiangyu Zhu, Xiuwei Du, Shengyun Shang, Jing Xu, Yu Li, Yunyun Cheng, Zhongfei Yang

“…This study aims to first establish whether to use HFNC or NIV based on comfort levels, and subsequently evaluate diaphragmatic function under equivalent comfort levels to determine the optimal modality for clinical application.MethodsA self-controlled, non-randomized study was conducted with 10 healthy respiratory physicians as participants. …”
Get full text

AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen by Zhen Gao, Qiyuan Bai, Mingyu Wei, Hao Chen, Yan Yan, Jiahao Mao, Xiangzhi Kong, Yang Yu

“…The SHAP algorithm also provided clear explanations and visualizations of the model's predictions. …”
Get full text

Immediate efficacy of acupuncture combined with active exercise as 10 min rapid therapy for pain and movement disorders in patients suffering from acute stiff neck: protocol for a... by Fan-rong Liang, Ya Huang, Qifu Li, Xin Tang, Taipin Guo, Gaoyangzi Huang, Xianmei Pei, Ziwen Chen, Zili Liu, Jinbo Sun, Jianglong Liao

“…Secondary outcomes include the effective rate at other time points (0–1, 2, 4, 6 and 8 min), Visual Analogue Scale score and cervical range of motion. …”
Get full text