Identifying key genes associated with recurrence in non-small cell lung cancer through TCGA and single-cell analysis by Weiyuan Li, Duo Han, Chunxiao Cao, Yuning Xie, Jingxia Shen

“…Additionally, the GSEA database was employed to visualize differential pathways and identify key genes. …”
Get full text

THE ROLE OF CHEMOKINES IN FIBROMYALGIA by Tuba Tülay Koca, Muhammed Seyithanoğlu, Fırat Sakınmaz

“…In our study, the importance of some chemokines and their receptors in FM and their relationship with pain and disease severity are analyzed. Material and Methods: This is a cross-sectional analytic study. …”
Get full text

Evaluating Synergistic Effects of Hyaluronic Acid, Human Umbilical Cord-Derived Mesenchymal Stem Cells, and Growth Hormones in Knee Osteoarthritis: A Multi-Arm Randomized Trial by Ismail Hadisoebroto Dilogo, Anissa Feby Canintika, Bernadus Riyan Hartanto, Jacub Pandelaki, Irsa Gagah Himantoko

“…This study aims to evaluate the efficacy and safety of combining hyaluronic acid (HA), human umbilical cord-derived mesenchymal stem cells (hUC-MSCs), and synthetic human growth hormone (somatotropin) in the treatment of knee OA, assessing pain relief, functional improvement, and cartilage regeneration. Methods: A four-arm, double-blind randomized trial was conducted with 51 knees from 28 subjects aged ≥50 with primary knee OA. …”
Get full text

The impact of emotional distress on response to radiofrequency ablation by Andrea Nikolis, Louis Nikolis, Zan Wynia, Carlos Murillo, Jason Friedrich, Yoni K. Ashar

“…To investigate the effects of baseline emotional distress on RFA treatment response. Methods:. Patients who completed self-reported surveys, Patient-Reported Outcomes Measurement System (PROMIS), from January 2021 through July 2023 were included. …”
Get full text

Comparison of total cold‐water immersion's effects to ice massage on recovery from exercise‐induced muscle damage by Mohammed Ali Fakhro, Fatima AlAmeen, Rim Fayad

“…Abstract Purpose The purpose of the study is to compare the effects of total cold‐water immersion to ice massage on muscle damage, performance, and delayed onset of muscle soreness. Methods Sixty participants were randomized into two groups where they completed a muscle damage protocol. …”
Get full text

Research trends in esketamine for depression over the past decade: a bibliometric analysis by Baozhou Zhang, Baozhou Zhang, Yifan Liu, Yifan Liu, Jinwei Zheng, Junping Chen

“…Hence, this paper employs bibliometric analysis to investigate the evolution and future research trajectories of this domain.MethodsWe utilize Excel, VOSviewer, and CiteSpace software to generate bibliometric network visualizations to analyze, construct, and quantitatively evaluate pertinent literature, which facilitates a lucid and intuitive presentation of the trends and frontiers in this research domain.ResultsAnnual publications increased from 2015 to 2024, totaling 925 articles, with 286 studies published in 2024. …”
Get full text

The efficacy of enhanced recovery program compared to routine care for patients undergoing knee replacement surgery: a systematic review and meta-analysis by Yanyan Ju, Guangling Wang, Xinglei Xiao

“…Abstract Objectives This meta-analysis compared enhanced recovery program with routine care for patients undergoing knee replacement surgery. Methods PubMed, Scopus, Web of Science, and the Cochrane Library, were systematically searched up to December 20, 2024, to identify randomized controlled trials comparing the effects of enhanced recovery with routine care on the outcomes of patients undergoing total knee replacement. …”
Get full text

Is perioperative use of a combination of pregabalin and naproxen superior to naproxen only in reducing pain in ankle fractures? A prospective, randomized, multicenter study by Gi Won Choi, Kwang Hwan Park, Yeo Kwon Yoon, Jin Woo Lee, Dong Woo Shim

“…The minimal clinically important difference of the visual analog scale (VAS) for pain was set at 1.8 out of 10. …”
Get full text

Macular Microcysts in Mitochondrial Optic Neuropathies: Prevalence and Retinal Layer Thickness Measurements. by Michele Carbonelli, Chiara La Morgia, Giacomo Savini, Maria Lucia Cascavilla, Enrico Borrelli, Filipe Chicani, Carolina do V F Ramos, Solange R Salomao, Vincenzo Parisi, Jerry Sebag, Francesco Bandello, Alfredo A Sadun, Valerio Carelli, Piero Barboni

“…<h4>Purpose</h4>To investigate the thickness of the retinal layers and to assess the prevalence of macular microcysts (MM) in the inner nuclear layer (INL) of patients with mitochondrial optic neuropathies (MON).<h4>Methods</h4>All patients with molecularly confirmed MON, i.e. …”
Get full text

A brief mindfulness intervention improves electrophysiological markers of attention in meditation-naïve individuals: the moderating role of inattention symptoms by Xiaoqian Yu, Xiaoqian Yu, Christine Vinci, Geoffrey F. Potts

“…This study examined the effects of a brief mindfulness intervention on attention and investigated whether baseline inattention symptoms moderated these effects in meditation-naïve university students.MethodsThis study employed a pretest-posttest, between-groups experimental design. …”
Get full text

Clinical Profile and Treatment Outcomes of Patients with Neovascular Glaucoma in a Tertiary Hospital in the Philippines by Angela Therese Y. Uy, MD, John Mark S. de Leon, MD

“…Objective: To report the clinical profile and treatment outcomes of neovascular glaucoma (NVG). Methods: A retrospective cohort study was done in a single tertiary hospital. …”
Get full text

Depression and anxiety in childhood-onset systemic lupus erythematosus: prevalence, associated factors, and impact on quality of life and family by Pitsamai Duangmala, Watchareewan Sontichai

“…This study aimed to determine the prevalence of clinically significant depression and anxiety, identify associated factors, and assess their impact on health-related quality of life (HRQOL) and family in patients with cSLE. Methods We conducted a cross-sectional study of cSLE patients, aged 8–18 years. …”
Get full text

Parameter algorithm-driven optimization of surgical approaches: An investigation based on T1 slope minus C2-7 cervical lordosis in patients with cervical degenerative diseases by Tao Liu, Zhongzheng Zhi, Shuiqiang Qiu, Jian Kang, Jinhao Miao, Zhimin He, Zude Liu

“…Purpose: The purpose of this study was to investigate surgical approach optimization based on T1S minus C2-7 CL in the perioperative management of CDD. Materials and Methods: Three hundred sixty-six patients diagnosed with CDD were enrolled from 2018 to 2023. …”
Get full text

Global trends in internet hospitals and electronic prescriptions: Insights for China by Kang Luo, Chengyu Sun, Furong Yu, Xiaoxia He, Yi Feng, Wensheng Zhu, Xue Yang

“…CiteSpace was used for bibliometric and visual analysis, identifying annual publication trends, collaboration networks, and keywords with strong citation bursts. …”
Get full text

Burned Area Segmentation in Optical Remote Sensing Images Driven by U-Shaped Multistage Masked Autoencoder by Yuxiang Fu, Wei Fang, Victor S. Sheng

“…Extensive experiments on two BAS datasets demonstrate that our DCNet outperforms the state-of-the-art methods.…”
Get full text

Diagnostic Accuracy of Non-Contrast Magnetic Resonance Imaging in Diagnosing Pituitary Micro-Adenoma, Taking Histopathology as Gold Standard by Sehar Sarfraz, Tayyaba Ali, Pakeeza Shafiq, Zartashia Khan, Waqar Azeem, Ghazala Rasool, Ehsan Ul Haq

“… Background: Pituitary microadenomas (PMs) are common benign tumors that are often not visualized even when they are present due to their asymptomatic nature. …”
Get full text

VALIDATION OF EQ-5D AND HADS INDICES TO EVALUATE QUALITY OF LIFE IN PATIENTS WITH PANNICULITIS by N. M. Savushkina, V. N. Amirdzhanova, S. I. Glukhova, O. N. Egorova, B. S. Belov

“…Objective: to assess the psychometric properties of EQ-5D and RAPID-3 indices in patients with panniculitis (PN). Subjects and methods. A total of 83 patients (80 women, 3 men) diagnosed with PN, followed up at the V.A. …”
Get full text

Platelet-rich plasma for the treatment of discogenic low back pain: a prospective randomized controlled trial by Xiangyi Wang, Siqi Wang, Jie Zhang, Gang Xie, Jin Zhang

“…ObjectiveThis study aimed to compare the therapeutic effect of PRP and methylene blue injection in patients with discogenic low back pain.MethodsA total of 40 patients with discogenic low back pain were randomly divided into two groups, with 20 patients in group A receiving platelet-rich plasma injections and 20 patients in group B receiving methylene blue injections. …”
Get full text

The impact of depression and anxiety disorders on postoperative outcomes for patients having total hip or knee arthroplasty: Protocol of a meta-analytic study from cohort studies. by Liang Lin, Qing Zhang, Min Xu, Zhihong Xiao, Guosong Xu, Zubing Mei

“…Potential publication bias will be visually assessed using funnel plots and statistically tested using Egger's test. …”
Get full text

Research trends and hotspots of single nucleotide polymorphisms in endometrial cancer: a bibliometric analysis by Renjie Wang, Zhihong Jia, Liang Peng, Jinghui Xu, Qiying Zhu, Yinghong Wu

“…This study explores the global research landscape of SNPs in EC, focusing on field evolution, key contributors, and emerging trends. Methods A systematic search of the Web of Science Core Collection (WoSCC) retrieved 838 publications on SNPs in EC from 1991 to 2024. …”
Get full text