Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Phar... by Kristina Zarif Attalla, Doaa H. Hassan, Mahmoud H. Teaima, Carol Yousry, Mohamed A. El-Nabarawi, Mohamed A. Said, Sammar Fathy Elhabal

“…The brain-targeting behavior of IN-ASN was visualized in rabbits via confocal laser scanning microscopy (CLSM). …”
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Faricimab for treatment-resistant choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD): seven-months results using artificial intelligence and... by Anna Heinke, Alexandra Warter, Ines D. Nagel, Akshay Agnihotri, Nehal Nailesh Mehta, Carlo Miguel B. Galang, Daniel N. Deussen, Dirk-Uwe G. Bartsch, Lingyun Cheng, Henry A. Ferreyra, William R. Freeman

“…Abstract Background To analyze the therapeutic response to faricimab 6 mg/0.05 ml in eyes with neovascular AMD (nAMD) with refractory intra- and/or subretinal fluid due to choroidal neovascularization (CNV), previously unresponsive to 4 mg monthly aflibercept and combination therapy with anti-VEGF and long-acting steroids. Methods A retrospective case series study of 22 eyes with unresponsive CNV, despite monthly intravitreal treatment (mean number of pre-faricimab injections: 35.52 ± 17.12). …”
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Evaluation of Comparative Efficacy of Goghrita with Saindhava Matrabasti versus Goghrita Matrabasti in Sciatica (Gridhrasi): A Randomised Controlled Trial Research Protocol by Girish Bhupal, Shweta Parwe, Milind Nisargandha, Shalini Pathania

“…Aim: To evaluate and compare the efficacy of Goghrita (cow clarified butter) with Saindhav Lavana (rock salt) Matrabasti (enema) versus Goghrita Matrabasti in Gridhrasi (sciatica). Materials and Methods: A randomised single-blind (assessor) superiority trial will be conducted at the Department of Panchakarma, Mahatma Gandhi Ayurved College Hospital and Research Centre (MGACHRC), Salod Hirapur (H), Maharashtra, India, from November 2024 to January 2026. …”
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The combination of hot water spray and subzero saline chilling improved chilling efficiency, meat quality, and sensory attributes by K. Kawamura, D. Ma, D.U. Ahn, H.-S. Seo, V. Hogan, L.N. Stephens, J. Moallem, J.W. Jin, I. Kang

“…Summary: Accelerated poultry processing is always desirable when the product quality, visual appearance, and sensory attributes are the same or better than the conventional processing. …”
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The accuracy of asynchronous tele-screening for detecting dental caries in patient-captured mobile photos: A pilot study by Alaa Husni Qari, Moayad Hadi, Alawi Alaidarous, Abdulrahman Aboalreesh, Majed Alqahtani, Ibraheem K. Bamaga, Jilen Patel, Mohamed Estai

“…Objectives: Unaided visual inspection is a primary dental screening technique. …”
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Study on Large‐Scale Brain Network Abnormalities in Patients With Beta‐Thalassemia by Mingrui Yang, Guowei Chen, Peng Peng, Cheng Tang, Chaotian Luo, Fei Peng, Rong Kong, Chunxia Zhu, Jiatong Liang

“…In contrast, FC was significantly increased in the dorsal sensorimotor network (dSMN) and posterior visual network (pVN). FNC analysis revealed that β‐TM patients exhibited enhanced connectivity between the lFPN and rFPN, as well as between the dorsal attention network (DAN) and VAN. …”
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Increasing motivation and well-being among medical students using curricular self-experience group sessions—a randomized controlled trial by Philipp Spitzer, Claire Mittmann, Janine Utz, Stefan Mestermann, Teresa Festl-Wietek, Johannes Kornhuber, Anne Herrmann-Werner

“…Therefore, this pilot study investigates whether promoting relatedness, autonomy and competence through participation in self-experience group therapy increases intrinsic motivation and reduces stress in medical students.Methods A longitudinal randomized controlled trial was conducted with 139 medical students. …”
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Impact of Hip Exercises on Postural Stability and Function in Patients with Chronic Lower Back Pain by Inhwan Leem, Gyu Bin Lee, Ji Won Wang, Sang Woo Pyun, Chang-Jun Kum, Jin Hyuck Lee, Hyeong-Dong Kim

“…Functional and clinical outcomes were assessed based on hip joint mobility, back extensor endurance, postural stability, and patient-reported outcomes, including visual analog scale (VAS) and Oswestry disability index (ODI) scores. …”
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Optic neuritis in various demyelinating diseases by A. K. Kalashnikova, D. D. Eliseeva, N. A. Andreeva, N. V. Zhorzholadze, I. A. Ronzina, R. Ts. Bembeeva, N. N. Venediktova, M. R. Kalganova, N. L. Sheremet

“…We assessed visual acuity (VA) in the acute phase and analyzed VA and average values of retinal nerve fiber layer thickness (RNFL) and retinal ganglion cell complex (RGC) thickness using OCT data 6 months after the onset of ON.Results. …”
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The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity by Katarina D. Milicevic, Violetta O. Ivanova, Tina N. Brazil, Cesar A. Varillas, Yan M.D. Zhu, Pavle R. Andjus, Srdjan D. Antic

“…This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds. Methods: Primary neuronal cultures were prepared from the cortex of newborn pups. …”
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Exploring Mortality and Prognostic Factors of Heart Failure with In-Hospital and Emergency Patients by Electronic Medical Records: A Machine Learning Approach by Yu CS, Wu JL, Shih CM, Chiu KL, Chen YD, Chang TH

“…The outcomes of those potential risk factors were visualized by different statistical analyses.Results: In total, 3871 hF patients were enrolled. …”
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Facing depression: evaluating the efficacy of the EmpkinS-EKSpression reappraisal training augmented with facial expressions – protocol of a randomized controlled trial by Marie Keinert, Lena Schindler-Gmelch, Lydia Helene Rupp, Misha Sadeghi, Klara Capito, Malin Hager, Farnaz Rahimi, Robert Richer, Bernhard Egger, Bjoern M. Eskofier, Matthias Berking

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Cinical, morphological and functional comparisons in acute period of ischemic hemispheric stroke by A. A. Kuznetsov

“…Statistical analysis was made with program Statistica 6.0 with the use of nonparametric methods (Mann-Whitney criterion), correlation analysis (Spearman’s rank correlation coefficient). …”
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Evaluation of the efficiency and safety of combined therapy with a symptomatic sustained-release drug and hyaluronic acid versus monotherapy with hyaluronic acid in patients with... by K. A. Berdyugin, I. V. Kadyntsev, O. V. Berdyugina, E. A. Taskina, N. G. Kashevarova

“…Searching for new treatment methods and regimens for OA is relevant.Objective: to evaluate the efficiency and safety of therapy with a symptomatic sustained-release drug (Alflutop) in combination with intra-articular hyaluronic acid (HA) injection versus monotherapy with HA in patients with knee OA in routine clinical practice.Patients and methods. …”
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Establishment of a patient-derived 3D in vitro meningioma model in xeno-free hydrogel for clinical applications by Mikkel Schou Andersen, Aaraby Yoheswaran Nielsen, Martin Wirenfeldt, Jeanette Krogh Petersen, Morten Winkler Møller, Christopher L. Powell, Anavaleria Castro, Grayson Herrgott, Tiit Mathiesen, Charlotte Aaberg Poulsen, Birgitte Brinkmann Olsen, Henning Bünsow Boldt, Christian Bonde Pedersen, Bo Halle, Frantz Rom Poulsen

“…Methods Four WHO grade 1 and one WHO grade 2 (third-passage, fresh) and 12 WHO grade 1 patient-derived meningioma cells (sixth-passage, frozen) and the malignant IOMM-Lee cell line were used to establish 2D and 3D models. …”
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Comparison of clinical efficacy between da Vinci® robotic surgery and laparoscopic surgery for rectal cancer: a report of 550 cases by Zhang Cheng, Ma Rui, Duan Fuxiao, Gao Guangrong, Li Da

“…There are no significant differences in other perioperative outcomes and long-term survival, indicating that both methods are safe and effective.…”
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Epidemiological Characteristics and Trends in the Incidence of Newly Diagnosed Pulmonary Tuberculosis in China from 2016 to 2022 by Caihong Xu, Yaxin Wen, Dongmei Hu, Yuhong Li, Yanlin Zhao

“…Descriptive epidemiological methods were used to analyze the population distribution, and temporal and spatial distribution (also known as the three-dimensional distribution in epidemiology). …”
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Prognostic value of tumor-infiltrating T-lymphocytes density in the therapeutic response to initial platinum-based chemotherapy in patients with non-small cell lung cancer by Novaković-Lacković Lora, Latinović-Tadić Ljilja, Stanetić Mirko, Lacković Marko

“…To assess the density of CD4+ and CD8+ T-lymphocytes, the number of lymphocytes was determined at ×200 magnification (1.1 mm2). Three visual fields with the densest lymphocyte infiltrate were selected for counting, and the values of all individual fields were added up. …”
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Overloaded Vertebral Body Following Consecutive Three‐Level Hybrid Surgery Comparing with Anterior Cervical Discectomy and Fusion by Shi‐hao Chen, Ya‐ling Li, Hao Liu, Ting‐kui Wu, Kang‐kang Huang, Ming‐he Yao, Bei‐yu Wang

“…Clinical outcomes were evaluated using visual analog scale (VAS) scores for neck and arm pain, Japanese Orthopedic Association (JOA) scores, and neck disability index (NDI) scores. …”
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Clinical Characteristics, Risk Factors, and Predictors of Nonobese Fatty Liver Disease: A Cross-Sectional Study by Zhang X, Wang S, Xu S, Min R, Ling Y, Sun S, Gong R

“…Correlation between non-obese fatty liver and high blood lipids, hypertension, hyperuricemia, diabetes, thyroid dysfunction were analyzed using the Pearson and Spearman methods. ROC curve was used to evaluate the diagnostic effect of the indicator.Results: Compared with the normal group, age, proportion of males, ALT, AST, GGT, ALP, TG, TC, BUN, Cr, UA, TSHI, TT4RI, FT3/FT4, TSH, FT3, FBG, SBP, DBP and BMI in the disease group were significantly higher. …”
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