Home-based self-administered transcranial direct current stimulation for women affected by primary dysmenorrhoea in Northeastern Brazil: a protocol study by Thiago Anderson Brito De Araújo, Edson Silva-Filho, Rodrigo Pegado, Tatiana Camila de Lima Alves da Silva, Yvinna Tamiris Rodrigues, Paloma Cristina Alves de Oliveira, Ervinas Bernatavicius, Alexander Anthony Cook, Emilè Radytè, Maria Thereza Micussi

“…Primary outcome will be pain according to visual analogue scale. Quality of life, premenstrual symptoms screening, depression, anxiety, physical performance, electroencephalography and participants’ satisfaction will be the secondary outcomes. …”
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Time-Intensity Curve Analysis of Contrast-Enhanced Ultrasound for Non-Ossified Thyroid Cartilage Invasion in Laryngeal Squamous Cell Carcinoma by Milda Pucėtaitė, Dalia Mitraitė, Rytis Tarasevičius, Davide Farina, Silvija Ryškienė, Saulius Lukoševičius, Evaldas Padervinskis, Valdas Šarauskas, Saulius Vaitkus

“…<b>Objective:</b> This study aimed to assess the diagnostic value of contrast-enhanced ultrasound (CEUS) time–intensity curve (TIC) parameters in detecting non-ossified thyroid cartilage invasion in patients with laryngeal squamous cell carcinoma (SCC). <b>Methods</b>: A CEUS TIC analysis was performed on 32 cases from 27 patients with histologically confirmed laryngeal SCC. …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…., from self-directed to specialized care) for caregivers of youth with chronic illnesses. <b>Methods</b>: The review methodology was co-designed with four caregivers. …”
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Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

“…<b>Introduction</b>: This study aimed to capture the early metabolic changes before osteoporosis occurs and identify metabolomic biomarkers at the osteopenia stage for the early prevention of osteoporosis. <b>Materials and Methods</b>: Metabolomic data were generated from normal, osteopenia, and osteoporosis groups with 320 participants recruited from the Nicheng community in Shanghai. …”
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Maintenance of CPR skills among nursing students trained using Resuscitation Quality Improvement® program by Marilyn H. Oermann, Yolanda M. VanRiel, Robin W. Wagner, Kelli D. Whittington, Manisa Baker, Debra E. Stieve, Patrick C. Crane, Carol A. Vermeesch

“…Objective: The objective of this multisite longitudinal study was to examine the maintenance of adult and infant compressions and ventilation skills by nursing students at 3 and 6 months following practice with real-time feedback using the RQI® program. Methods: The effectiveness of brief practice of CPR skills at the RQI® simulation station on the maintenance of skills was analyzed with 238 nursing students from six universities across the United States. …”
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Predicting diabetic retinopathy stages using a simple nerve conduction measuring device, DPNCheck®: a retrospective observational study by Mayu Sakai, Mayu Sakai, Mayu Sakai, Takehiro Kato, Takehiro Kato, Takuma Ishihara, Ken Takao, Ken Takao, Tokuyuki Hirose, Tokuyuki Hirose, Sodai Kubota, Sodai Kubota, Saki Kubota-Okamoto, Saki Kubota-Okamoto, Toshinori Imaizumi, Toshinori Imaizumi, Yoshihiro Takahashi, Yoshihiro Takahashi, Masami Mizuno, Masami Mizuno, Takuo Hirota, Takuo Hirota, Yukio Horikawa, Yukio Horikawa, Hirokazu Sakaguchi, Hirokazu Sakaguchi, Shin Tsunekawa, Daisuke Yabe, Daisuke Yabe, Daisuke Yabe

“…Aims/introductionDiabetic retinopathy (DR) often remains asymptomatic until it reaches advanced stages, when delayed treatment can lead to irreversible visual impairment. To promote timely ophthalmology visits, this study investigated the utility of a simple nerve conduction device, DPNCheck®, as a predictor of DR severity. …”
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N-Butyl-2-Cyanoacrylate Adhesive Versus Absorbable Tacks in Laparoscopic Groin Hernia Repair: A Multicenter Randomized Clinical Trial by Clayton C. Petro, MD, Benjamin K. Poulose, MD, Michael J. Rosen, MD, Alfredo M. Carbonell, II, DO, Adel G. El-Ghazzawy, MD, Jeremy A. Warren, MD, Emanuele Lo Menzo, MD, Ajita S. Prabhu, MD, David M. Krpata, MD, Samuel Szomstein, MD, Vimal Narula, MD, Crystal F. Totten, MD, Kelly R. Haisley, MD, Andrew C. Bernard, MD, Henrik O. Berdel, MD, Jessica K. Reynolds, MD, Zachary D. Warriner, MD, John S. Roth, MD

“…The primary outcome was improvement in pain (visual analog scale [VAS]) at 6 months. The noninferiority margin was 0.9 (α = 0.025; β = 80%). …”
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Utilization of magnification devices in Vietnam’s dental practice and education: an online survey by Minh-Hieu Nguyen Tran, Anh Huynh Bui, Lan-Anh Hoang Le, Thuy-Trang Thi Huynh, Phuong-Doan Phan, Thuan-Loc Tran, Nguyen-Tra-Mi Le, Thu-Tra Nguyen, Hoang-Vinh Le, Dai-Phong Lam, Quoc-Viet Lam, Tran-Lan-Khue Pham, An-Tran Pham, Van-Khoa Pham

“…This study aimed to assess magnification device utilization in Vietnamese dental practice and education, with a pioneering focus on 3D-DOMs. Methods An online, questionnaire-based observational survey was conducted from October to December 2024. …”
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Clinical and mycological investigations of post‐COVID‐19 acute invasive fungal sinusitis by Samah Mahmoud Eldsouky, Amany K. Shahat, AL‐Shaimaa M. AL‐Tabbakh, Shaymaa M. Abd El Rahman, Yasmin M. Marei, Lina Abdelhady Mohammed, Ola Samir El‐Shimi, Dina Saad Abdelmotaleb, Yomna Mohammed Marei, Mohamed Sabry Abd Elraheam Elsayed

“…Headache and facial pain, ophthalmoplegia, visual loss, and blindness represented 100%, 66.7%, 90%, and 53.3% of the cases, respectively. …”
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Neosols, relict paleosols, and alterites in the Transmexican Volcanic Belt, Morelos state: Characterization and regional spatial distribution by Jorge Enrique Gama-Castro, David Flores-Román, Elizabeth Solleiro-Rebolledo, Carolina Jasso-Castañeda, Ernestina Vallejo-Gómez, Ana María Rocha-Torrallardona, José Luis Villalpando-González

“…In our study, the interpretation of thematic cartography and the application of sophisticated methods like remote sensing and laboratory automated image analyses combined with field transects, provided a unique set of tools for generating and synthesizing data. …”
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Levels of physical activity in a large international cohort of patients with systemic lupus erythematosus by Laurent Arnaud, Matteo Piga, Manuel Francisco Ugarte-Gil, Christelle Sordet, Philippe Mertz, Luc Pijnenburg, Marina Rinagel, Lou Kawka, Sophie Geneton, Julien Blaess, Timothée Mischler, Juan C Sarmiento-Monroy

“…The aim of this study was to assess PA level and characteristics in a large international cohort of patients with SLE.Methods PA was assessed in metabolic equivalent of tasks (METs) using the International Physical Activity Questionnaire (IPAQ) and classified into three levels: low, moderate and high PA. …”
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Investigating the effects of mobile bottom fishing on benthic carbon processing and storage: a systematic review protocol by Stacey L. Felgate, John Aldridge, Stefan G. Bolam, Sarah Breimann, Emil de Borger, Jolien Claes, Jochen Depestele, Graham Epstein, Clement Garcia, Natalie Hicks, Michel Kaiser, Jack H. Laverick, Gennadi Lessin, Finbarr G. O’Neill, Sarah Paradis, Ruth Parker, Ryan Pereira, Alex J. Poulton, Claire Powell, Craig Smeaton, Paul Snelgrove, Justin Tiano, Johan van der Molen, Sebastiaan van de Velde, Marija Sciberras

“…Results will be reported in narrative and quantitative syntheses using a variety of visual tools including forest plots. Meta-analysis will be conducted where sufficient data exists.…”
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Mapping Antarctic Blue Ice Areas With Sentinel-2A/B Images and LightGBM Model by Xiaolong Teng, Jiahui Xu, Xiangbin Cui, Guitao Shi, Zhengyi Hu, Qingyu Gu, Bailang Yu, Jianping Wu, Yan Huang

“…While satellite remote sensing is effective in mapping BIAs, traditional methods rely on limited spectral bands and linear models with inherent limitations. …”
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Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights by Waad A. Samman, Esraa M. Mosalam, Esraa M. Mosalam, Dalia S. Saif, Mahmoud S. Abdallah, Mahmoud S. Abdallah, Abdel-Aziz A. Zidan, Amany Said Sallam, Shimaa Abdelsattar, Fatma Omar Khalil, Amany E. Elashkar, Somia Mokabel Mohamed, Mohamed Al-Ghannam, Hend E. Abo Mansour, Hend E. Abo Mansour

“…Our study aims to investigate the implication of Wnt/ β-catenin pathway in development of KOA by detection of the downstream target genes and their crosstalk with miR-214 in patients with KOA and to correlate that with the clinical findings.MethodsSixty participants were involved in the study. …”
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Effects of herbal medicines (Eunkyosan/Yin qiao san and Samsoeum/Shen su yin) for treating the common cold: A randomized, placebo-controlled, multicenter clinical trial by Kwan-Il Kim, Minna Hong, Yang-Chun Park, Beom-Joon Lee, Kitae Kim, Byoung Kab Kang, Jun-Yong Choi

“…This study aimed to evaluate the effectiveness and safety of EKS and SSE for treating the common cold. Methods: A randomized, patient-assessor-blind, placebo-controlled, parallel, and multicenter clinical trial was conducted. …”
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CHANGES IN CALPROTECTIN LEVEL, ITS RELATIONSHIP TO THE CLINICAL AND LABORATORY PARAMETERS OF DISEASE ACTIVITY AND SIGNIFICANCE FOR PREDICTING THE THERAPEUTIC RESPONSE IN RHEUMATOID... by A. O. Pchelintseva, A. P. Zhornyak, N. G. Ionichenok, E. Yu. Panasyuk, A. E. Ilyina, I. A. Andrianova, E. E. Gubar, E. S. Tsvetkova, M. V. Cherkasova, E. N. Aleksandrova, L. N. Denisov, E. L. Nasonov

“…To assess RA activity, tender and swollen joint count, pain, patient’s and physician’s assessment of global disease activity on 100-mm visual analogue scale and DAS28 were used. Functional status was evaluated by HAQ and RAPID3. …”
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Effectiveness of Local Wound Infiltration with Morphine, Ketorolac, and Bupivacaine Compared to Bupivacaine Alone Following Tibial Osteotomy in Pediatric Patients: A Randomized Con... by Piyanuch Musikachart, Thanase Ariyawatkul, Jidapa Wongcharoenwatana, Nath Adulkasem, Perajit Eamsobhana

“…Primary outcomes were Visual Analog Scale (VAS) pain scores measured every 4 hours during the first 48 hours after surgery. …”
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SUBSTANTIATION FOR PRINCIPLES OF AESTHETIC STOMATOLOGY by I.K. Lutskaya

“…Different methods of dental bleaching are to be considered as well as minor dissection (microabrasion) and grinding the prismless layer off the enamel surface. …”
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Machine learning based assessment of hoarseness severity: a multi-sensor approach centered on high-speed videoendoscopy by Tobias Schraut, Anne Schützenberger, Tomás Arias-Vergara, Melda Kunduk, Matthias Echternach, Stephan Dürr, Julia Werz, Michael Döllinger

“…IntroductionFunctional voice disorders are characterized by impaired voice production without primary organic changes, posing challenges for standardized assessment. Current diagnostic methods rely heavily on subjective evaluation, suffering from inter-rater variability. …”
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Identifying key components of a global conceptual framework for adolescent nutrition: Review, nominal group technique and youth co-design by Marion L Roche, Deepika Sharma, Sarah Kehoe, Sara Estecha-Querol, Catharine A K Fleming, Amir A Samnani, Milca J Cameseria, Dipty Chowdhury, Webster Isheanopa Makombe, Amanda Murungi Eunice, Muhammad Sarim Raza, Miriam Shindler, Kesso G van Zutphen-Küffer, Stephanie V Wrottesley

“…This paper presents the methods used to identify the need for and to prioritise the key components of a new framework.Methods A literature review was conducted to identify and summarise available frameworks for adolescent nutrition (10–19 years). …”
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