Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients by Chen Y, Zhang ZJ, Zhang XF, Peng Y, Jiao Z, Wu JX

“…A population PK/PD model was established, and goodness-of-fit and visual predictive check plots were utilized to evaluate the model’s accuracy. …”
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Investigating Anxiety, Mobility, Disability and Proprioception in Adults with Mild Neck Pain: A Cross-Sectional Study by Pablo Mleziva, Eric Glenn Johnson, Everett B. Lohman, Madeha Jaber, Lillian Mleziva, Noha S. Daher

“…This study examines the differences in anxiety, neck movement, disability, and proprioception in people with chronic SCNP (12 females and 4 males, age = 28.1±4.0 years) and people without neck pain (17 females and 6 males, age = 25.8±3.1 years). Materials and Methods: A cross-sectional study with 39 participants was conducted. …”
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Comparison of the Effect of Ranibizumab and Aflibercept on Changes in Macular Choroidal Thickness in Patients Treated for Diabetic Macular Edema by Valérie Sarda, Pauline Eymard, Linda Hrarat, Franck Fajnkuchen, Audrey Giocanti-Aurégan

“…The aim of this study was to assess the effect of intravitreal injections (IVI) of ranibizumab and aflibercept on the choroidal thickness (CT) in patients with treatment-naive diabetic macular edema (DME) before and after monthly IVI. Patients and Methods. Prospective monocenter study. Inclusion criteria were treatment-naive DME eyes without concomitant panretinal photocoagulation, associated with a decrease in best-corrected visual acuity ≤75 letters on the Early Treatment Diabetic Retinopathy Study (ETDRS) scale. …”
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Intensive versus Guideline Blood Pressure and Lipid Lowering in Patients with Previous Stroke: Main Results from the Pilot 'Prevention of Decline in Cognition after Stroke Trial' (... by Philip M Bath, Polly Scutt, Daniel J Blackburn, Sandeep Ankolekar, Kailash Krishnan, Clive Ballard, Alistair Burns, Jonathan Mant, Peter Passmore, Stuart Pocock, John Reckless, Nikola Sprigg, Rob Stewart, Joanna M Wardlaw, Gary A Ford, PODCAST Trial Investigators

“…We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive outcomes in patients with recent stroke in a pilot trial.<h4>Methods</h4>In a multicentre, partial-factorial trial, patients with recent stroke, absence of dementia, and systolic BP (SBP) 125-170 mmHg were assigned randomly to at least 6 months of intensive (target SBP <125 mmHg) or guideline (target SBP <140 mmHg) BP lowering. …”
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Amyloid-beta 40 as a biomarker of cognitive impairment in acute ischemic stroke by Aleksey A. Kulesh, Viktor E. Drobakha, Elena M. Kuklina, Vladimir V. Shestakov

“…Aim: to study the role of amyloid-beta 40 (Aβ 40) in the development of cognitive impairment in acute ischemic stroke.Materials and methods. The study included 70 patients aged 33–86 years, 46 men and 24 women. …”
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Evaluation of corneal epithelial mapping in type-2 diabetes mellitus by Esraa R. Hassaan, Mostafa M. Bahgat, Ahmed F. El-Shahed

“…Setting BADR University Hospital, and Al-Mashreq Eye Center, Cairo, Egypt. Patients and methods A prospective, comparative study that included, total 96 eyes: 48 eyes of 24 DM-2 patients, and 48 eyes of 24 healthy participants. …”
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Comparison of Presbyopia Between Glaucoma Patients Using Prostaglandin F Receptor Agonists and Fixed Combination Therapy by Ayaki M, Hanyuda A, Negishi K

“…Masahiko Ayaki,1,2 Akiko Hanyuda,1 Kazuno Negishi1 1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan; 2Grand Central Tower Tokyo Eye Clinic, Minato-ku, Tokyo, JapanCorrespondence: Masahiko Ayaki, Grand Central Tower Tokyo Eye Clinic, 2-16-3 Konan, Minato-ku, Tokyo, 1080075, Japan, Email mayaki@olive.ocn.ne.jp Kazuno Negishi, Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan, Email kazunonegishi@keio.jpObjective: The purpose of this study was to compare the near add power among glaucoma patients using prostaglandin F (FP) receptor agonists and fixed combination therapies and controls.Methods: Participants were aged from 40 to 69 years and phakic with visual acuity of 20/25 or better, and included 2200 controls, 784 patients using FP receptor agonist for primary open-angle glaucoma (FP), and 412 patients using fixed combination (Combi). …”
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Efficacy of ketorolac versus tramadol for analgesia during percutaneous vertebroplasty

“…Objective To evaluate the efficacy of ketorolac versus tramadol used in analgesia during percutaneous vertebroplasty (PVP) in patients with osteoporotic vertebral compression fracture(OVCF). Methods This retrospective study selected 126 patients who underwent PVP for treatment of osteoporotic vertebral compression fracture. …”
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Patient Satisfaction and Resource Utilization Following Introduction of Long-Acting Injectable Buprenorphine (LAIB) in Scottish Prisons by Sayers C, Mogford D

“…The following outcomes were evaluated at 12, 24, and 52 weeks: patient satisfaction using the Treatment Satisfaction Questionnaire for Medication (TSQM), patient-reported craving using a 100 mm visual analog scale (VAS), and opioid withdrawal using the Clinical Opiate Withdrawal Scale (COWS). …”
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A scoping review of national policies for hierarchical medical system in China since the 2009 health reform by Tingting Cai, Yuting Hua, Leyi Fang, Yunhui Xia, Jiantong Shen, Jiantong Shen, Jianlin Lou

“…We aim to summarize and review the evolution of China’s hierarchical medical system policy.MethodsEligible policies were identified between March 7, 2009 and December 31, 2022, by searching the official websites of the PKULAW Database, the Chinese State Council, and related ministries. …”
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Mix-­and­-match Implantation of Multifocal and Extended Depth of Focus IOLs by K. B. Pershin, N. F. Pashinova, А. Yu. Tsygankov, E. A. Antonov, I. V. Kosova, L. V. Batalina

“…Purpose: Analysis of results of combined implantation of non­diffractive IOL with extended depth of focus and multifocal IOL.Materials and methods. The study included 40 patients (80 eyes) after cataract phacoemulsification or clear lens removal with a mean follow­up of 15.4 ± 1.2 (12–22) months. …”
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Abstract 212: Percutaneous Carotid access in Mechanical Thrombectomy ‐ a safe alternative to transfemoral approach by Sonia Bellara, James Hiana, Daniel Zumofen, Yohannes Mulatu

“…NIHSS on arrival was 14 for expressive aphasia, right visual field defect, right facial weakness, significant dysarthria, right hemiparesis, and sensory defect. …”
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Preoperative Spino Cranial Angle Predicts Adjacent Segment Degeneration After Single-Level Anterior Cervical Discectomy and Fusion by Li Y, Cheng P, Zhang X, Cheng C

“…The spino cranial angle (SCA), a novel sagittal parameter reflecting head-to-cervical alignment, may be associated with ASD, yet its predictive value remains unclear.Methods: A total of 98 patients who underwent single-level ACDF with at least 24 months of follow-up were retrospectively analyzed. …”
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The Effectiveness of a Specific Exercise Program in Alleviating Work-Related Neck and Upper Back Pain and Improving Mood State in Various Occupational Populations—A Randomized Cont... by Anastasia Beneka, Paraskevi Sakellari, Katerina Daskalaki, Paraskevi Malliou, Theodoros Konstantinidis

“…This study aimed to investigate whether a specific exercise program could alleviate neck and upper back pain symptoms and improve mood state among healthcare and office employees during the post-COVID-19 period. <i>Materials and Methods</i>: This was an unblinded (open label) randomized controlled trial (both the participants and the researchers knew which treatment or intervention was being administered). …”
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Exploring shared pathogenic mechanisms and biomarkers in hepatic fibrosis and inflammatory bowel disease through bioinformatics and machine learning by Shangkun Li, Haoyu Li, Mingran Qi

“…Current limitations in identifying common biomarkers for comorbid cases impede early dual diagnosis and therapeutic interventions.MethodsDifferentially expressed genes (DEGs) were screened, followed by Weighted Gene Co-expression Network Analysis (WGCNA) to identify disease-associated modules. …”
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Long-term results of orthokeratology correction combined with 0.01 % atropine instilliations in children and adolescents with progressive myopia of various degrees by T. Yu. Verzhanskaya

“…Over the 36 months’ period, 0.01% atropine showed no negative effect on the quality of visual functions of subjects wearing OK lenses.…”
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Unconscious information processing of table tennis athletes in a masked priming paradigm: an event-related potentials (ERP) study by Fanying Meng, Lijiao Chen, Chun Xie, Jiadong Zheng, Ning Chen, Fanghui Qiu, Jiaxian Geng

“…This study explored unconscious information processing and brain activity in highly trained table tennis athletes and non-athletes in general contexts. Methods Twenty table tennis athletes (six females, mean age = 20.38 ± 1.28, mean ± standard error) and 21 aged-matched college students (eight females, mean age = 19.81 ± 1.29) were recruited for this study. …”
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Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…The optimal interval between staged procedures and effective strategies to minimize postoperative pain to enhance rehabilitation and mobility remain poorly understood. Methods: 160 consecutive patients undergoing staged bilateral TKA between August 2017 and January-2021 was retrospectively reviewed. …”
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Identification of new diagnostic targets for hepatitis B virus‐induced liver fibrosis by Ying Wang, Shuo Qin, Meng Yang, Xiaoling Wang

“…A heat map was drawn to visualize the expression patterns of the differentially expressed mRNAs. …”
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Enhancing Clinical Nursing Guidance and Optimizing Care Processes for Improved Hand-Foot-and-Mouth Disease Treatment Outcomes by Zhao Y, Ju H

“…Ying Zhao,1 Hao Ju2 1Department of Dermatology, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China; 2Department of Oncology, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of ChinaCorrespondence: Hao Ju, Email juhao1986@163.comObjective: To evaluate the efficacy of modified skin care intervention in pediatric Hand-Foot-and-Mouth Disease (HFMD) patients, focusing on its impact on skin recovery, pain management, and herpes healing.Methods: Clinical data from 130 HFMD children (February 2023–June 2024) were retrospectively analyzed. …”
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