Regulation of microtubule nucleation in glioblastoma cells by ARF GTPase-activating proteins GIT1 and GIT2 and protein kinase C by Vadym Sulimenko, Eduarda Dráberová, Vladimíra Sládková, Tetyana Sulimenko, Věra Vosecká, Omar Skalli, Pavel Dráber

“…To further investigate their role in microtubule modulation, we examined the function of GITs in microtubule nucleation and the involvement of protein kinase C (PKC) in this process. Methods Glioblastoma cell lines with depleted GIT protein levels were generated using shRNA lentiviral vectors. …”
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Changes in mental health and joint-specific patient-reported outcome measures following arthroscopic shoulder labral repair by Kristen E. Hines, BS, Natalie A. Lowenstein, MPH, Jillian L. Mazzocca, BA, Cale A. Jacobs, PhD, Elizabeth G. Matzkin, MD

“…It was hypothesized that low preoperative mental health, measured by the Veterans RAND 12-Item Health Survey Mental Component Score (VR-12 MCS), would demonstrate inferior patient-reported outcome measures preoperatively and postoperatively, but that improvement would be similar. Methods: Fifty subjects undergoing a primary arthroscopic anterior labral repair were included. …”
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Personalized Video‐Based Educational Platform to Improve Stroke Knowledge: A Randomized Clinical Trial by Christopher G. Favilla, Navpreet Reehal, Stephanie R. Cummings, Rebecca Burdett, Laura A. Stein, Banafsheh Shakibajahromi, Kristy Yuan, Kelly L. Sloane, Scott E. Kasner

“…Here, we aimed to quantify the impact of a personalized video‐based educational platform to test the hypothesis that it improves patient satisfaction and stroke knowledge. Methods and Results In a single‐center pilot randomized trial, all patients with stroke and caregivers received standard stroke education during the hospitalization, but half were randomized to receive access to MyStroke, a personalized educational platform that provided brief videos about their stroke, risk factors, medications, and poststroke lifestyle. …”
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Differential relationships among homocysteine levels, cognitive deficits, and low-frequency fluctuation in brain activity in bipolar disorder with suicidal ideation by Yuanyuan Huang, Sumiao Zhou, Shixuan Feng, Hehua Li, Ziyun Zhang, Chenyu Liu, Junhao Li, Wei Han, Kai Wu, Xingbing Huang, Fengchun Wu

“…However, the relationship among spontaneous brain activity, Hcy levels, and cognitive deficits in patients with BDSI remains unclear. Methods A total of 74 participants were enrolled, comprising individuals with BDSI (n = 20), BD patients without suicidal ideation (BDNSI) (n = 24), and age-/sex-matched healthy controls (HC) (n = 30). …”
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The VRIMM study: Virtual Reality for IMMunisation pain in young children—protocol for a randomised controlled trial by Simon Craig, Kirrily Ellerton, Harishan Tharmarajah, Rimma Medres, Lona Brown, David Ringelblum, Kateena Vogel, Amanda Dolphin, Sue McKellar, Fiona Bridson, Marietta John-White

“…In this study, we aim to compare the effectiveness of VR to standard care in a general practice setting as a distraction technique to reduce pain and distress in 4-year-old children receiving routine immunisations.Methods and analysis The study is a randomised controlled clinical trial comparing VR with standard care in 100 children receiving routine 4-year-old vaccination. …”
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Mental health impact of a large-scale industrial fire on exposed residents in France: the post fire 76 health survey by Anne-Laure Perrine, Gaëlle Pédrono, Pauline Morel, Pascal Empereur-Bissonnet, Jean-Baptiste Richard, Franck Golliot, Abdelkrim Zeghnoun, Myriam Blanchard, Abdessatar Saoudi, Emmanuelle Le Lay, Maria El Haddad, Yvon Motreff

“…This survey aimed to assess the impact of the fire on the mental health of the exposed population fifteen months later. Methods A random representative stratified sample was selected from the exposed population in Rouen and a non-exposed population in a nearby city. …”
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Health Anxiety and Its Relationship with Academic Performance and Learning Styles among Nursing Students during COVID-19 Pandemic by Hossein Namdar Areshtanab, Mina Hosseinzadeh, Hossein Ebrahimi, Mohammad Arshadi Bostanabad, Nazila Sepehrnia

“…Introduction: This study aimed to investigate health anxiety and its relationships with academic performance and learning styles among nursing students during the COVID-19 pandemic. Methods: A cross-sectional design was employed, involving 365 participants selected through stratified random sampling in Iran in 2021. …”
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Feasibility study of using the PREDICT kidney tool for patients with localised renal cell carcinoma by Panayiotis Laouris, Chiara Re, Georgia Stimpson, Axel Bex, James Blackmur, Alexander Laird, Carley Batley, Grant D. Stewart, Hannah Harrison, Juliet A. Usher‐Smith

“…Endpoints Patient uptake into the study, completeness of data collection, consultation duration, the acceptability of the tool to both patients and clinicians, clinician adherence to the study “best‐practice” guide, variability in tool usage across clinicians and sites and patient‐level clinical outcomes including subjective and objective comprehension of risk of recurrence and follow‐up, perceived risk of cancer recurrence, risk conviction, satisfaction with the information provided on risk of recurrence and follow‐up, and fear of cancer recurrence. Patients and Methods We aim to recruit 60 patients from three hospitals in England and Scotland. …”
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Intraoperative Near-Infrared Autofluorescence and Indocyanine Green Imaging to Identify Parathyroid Glands: A Comparison by Max Lerchenberger, Norah Al Arabi, Julia K. S. Gallwas, Herbert Stepp, Klaus K. J. Hallfeldt, Roland Ladurner

“…To investigate the feasibility of near-infrared autofluorescence (AF) and indocyanine green (ICG) fluorescence to identify parathyroid glands intraoperatively. Methods. Fluorescence imaging was carried out during open parathyroid and thyroid surgery. …”
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Bioactive glass grants equivalent fusion compared to autologous iliac crest bone for ALIF: a within‐patient comparative study by Marc Szadkowski, Sami Bahroun, Ivan Aleksic, Michiel Vande Kerckhove, Sonia Ramos‐Pascual, Mo Saffarini, Vincent Fière, Henri d’Astorg

“…Abstract Purpose To determine within‐patient fusion rates of chambers filled with bioactive glass versus autologous iliac crest bone on computed tomography (CT) following anterior lumbar interbody fusion (ALIF). Methods A consecutive series of 40 patients (58 levels) that underwent single‐level (L5‐S1 only) or two‐level (L5‐S1 and L4‐L5) ALIF were assessed. …”
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Limitations of informed consent in routine clinical practice - An observational survey study to characterize patient populations with limited understanding of the routine informed... by Elisabeth Bär, Tobias Bock, Bettina Bock, Anne Goldbach, Julia Heusner, Saskia Schuppener, Sven Bercker

“…This study aims to identify patient groups with limited understanding of the informed consent process for anaesthesia and to assess the factors influencing their understanding. Methods A monocentric, prospective, observational survey study was conducted at the Anaesthesia Clinic of the University Hospital of Leipzig. …”
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Precise identification of medulloblastoma in MRI images using a convolutional neural network integrated with a self-attention mechanism by Chenhao Fang, Chao Li, Huiqing Liu, Qiang Zhou, Shuo Li, Hong Chen, Xianzhen Chen, Zhaoli Shen

“…This study proposed a new hybrid deep learning model named InceptentionNet, combining Inception and self-attention mechanisms to recognize MB with MRI images. Methods InceptentionNet integrated multiscale feature extraction and dynamic focus on relevant regions. …”
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Alopecia patterns and trichoscopic findings in patients with autosomal recessive congenital ichthyosis by Anissa Zaouak, MD, Wafa Jouini, MD, Ghaith Abdessalem, PhD, Sonia Abdelhak, PhD, Houda Hammami, MD, Cherine Charfeddine, PhD, Samy Fenniche, MD

“…This study aims to comprehensively characterize the clinical and trichoscopic findings of alopecia in ARCI patients. Methods:. A prospective study spanning from January 2019 to December 2021 (3 years) was conducted at the Dermatology Department of Habib Thameur Hospital, Tunis, Tunisia. …”
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Propofol‐alone sedative efficacy in observational biliopancreatic endoscopic ultrasound by Hisaki Kato, Yuki Kawasaki, Kazuya Sumi, Yuki Shibata, Norihiro Nomura, Jun Ushio, Junichi Eguchi, Takayoshi Ito, Haruhiro Inoue

“…In this study, we retrospectively evaluated the usefulness and safety of propofol without analgesics for sedation in biliopancreatic observational EUS. Methods This single‐center retrospective study included 516 observational biliopancreatic EUS procedures using propofol alone performed between April 2021 and March 2023. …”
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The Significance of Cellular Senescence Hub Genes in the Diagnosis and Subtype Classification of a Comprehensive Database of Gene Expression in Intervertebral Disc Degeneration by Fei Liu, Silong Gao, Ji Yin, Chao Song, Yongliang Mei, Zhaoqiang Wang, Zongchao Liu

“…However, the precise role of CS and its associated genes in IVDD remains unclear. Methods In this study, we performed differential expression analysis on the GSE124272 and GSE150408 datasets from the GEO database and identified 53 differentially expressed cellular senescence‐related genes (CSRGs). …”
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CONE-BEAM COMPUTED TOMOGRAPHY IN PALEOANTHROPOLOGY by A. Yu. Vasil’ev, A. P. Buzhilova, E. A. Egorova, D. V. Makarova, N. Ya. Berezina, I. S. Zorina, V. I. Khartanovich

“…Objective: to study the capabilities of cone-bean computed tomography (CBCT) in estimating the bone structure when analyzing anthropological findings.Material and methods. Twenty-four bone fragments (remains) of Napoléon Bonaparte Imperial Army soldiers who had died at a Königsberg military hospital during their retreat from Russia in the War of 1812 were examined by CBCT. …”
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Mixed ciliary-capsular fixation of a three-piece IOL during phacoemulsification in patients with the lenticular ligamentous-capsular system’s failure by B.E. Malyugin, E.N. Panteleev, L.L. Khapaeva, A.G. Savenkov

“…To evaluate clinical results of mixed ciliary-capsular fixation of a three-piece IOL in combination with the intracapsular ring’s implantation during phacoemulsification in patients’ zonular weakness caused by pseudoexfoliative (PEX) syndrome. Material and methods. This study included 78 patients (86 eyes) with complicated cataract and PEX syndrome associated with zonular weakness and natural lens instability. …”
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The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification by Xu Huang, Zhihong Pan, Lei Shen, Huan Chen, Chang Chen, Tingting Lv, Yuzhou Mei

“…This study aimed to elucidate the potential pharmacological mechanisms of WQD in GC therapy. Methods Active ingredients, corresponding targets, and GC-related genes were identified using public databases. …”
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Early experience with percutaneous photodynamic nails for sacral metastatic disease and insufficiency fractures: a retrospective cohort analysis of functionality and pain relief by Marilee J. Clunk, Marcos R. Gonzalez, Sonia E. Ubong, Alisha Sodhi, Joseph O. Werenski, Hayley M. Denwood, Daniel G. Tobert, Santiago A. Lozano-Calderon

“…The role of minimally invasive photodynamic nails (PDN) for treatment of these fractures remains poorly understood. Methods Patients with symptomatic impending pathologic fractures of the sacrum due to metastatic bone disease, multiple myeloma, or insufficiency fractures from radiation osteitis who underwent PDN stabilization were identified. …”
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The Role of Monochromatic Superb Microvascular Index to Predict Malignancy of Solid Focal Lesions: Correlation Between Vascular Index and Histological Bioptic Findings by Francesco Giurazza, Luigi Basile, Felice D’Antuono, Fabio Corvino, Antonio Borzelli, Claudio Carrubba, Raffaella Niola

“…Objectives: This study aims to assess the potential role of the ultrasound (US) monochromatic Superb Microvascular Index (mSMI) to predict malignancy of solid focal lesions, correlating the vascular index (VI) with bioptic histological results. Methods: In this single-center retrospective analysis, patients undergoing percutaneous US-guided biopsy of solid lesions were considered. …”
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