OCT predictors of retinal atrophy in neovascular age-related macular degeneration treated with aflibercept by Oscar M. Gagliardi, Ludovico Alisi, Giacomo Visioli, Federica Dini, Giuseppe M. Albanese, Stefano Scordari, Marco Marenco, Alessandro Lambiase, Rosalia Giustolisi

“…METHODS: OCT data collected at the time of nAMD diagnosis (T0), after the first (T1) and third (T2) intravitreal aflibercept injection, and 5y post-diagnosis (T3) were analyzed. …”
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Retrospective Case Analysis of Transnasal Endoscopic Resection of Benign Orbital Apex Tumors: Some Thoughts on Transnasal Endoscopic Surgery by Cheng Li, Yang Gao, Rongxin Chen, Chao Cheng, Pan Yin, Zhihui Zhang, Yinghao Wang, Yuekun Bao, Huan Ma, Jianbo Shi, Rong Lu

“…At each follow-up visit, the patients underwent measurement of their best-corrected visual acuity (BCVA), slit-lamp examination, indirect ophthalmoscopy, and visual field testing. …”
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The value of targeted CXCR4 18F-AlF-NOTA-pentixafor PET/CT for subtyping primary aldosteronism by Yushi Peng, Fangansheng Chen, Rui Yao, Junping Lan, Yinuo Fu, Kaifeng Ye, Zhiqiang Wang, Qianxiu Zhao, Xiaowei Ji, Kang Xia, Guoqing Zhu, Kewen Zheng, Xuemei Gu, Kun Tang, Kun Tang, Kun Tang

“…ObjectiveThe study aimed to investigate the diagnostic value of 18F-AlF-NOTA-Pentixafor PET/CT in subtyping primary aldosteronism (PA).MethodsThis study enrolled 88 patients with PA or nonfunctional adenoma (NFA) for 18F-Pentixafor PET/CT scan. …”
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Development of Machine-learning Model to Predict Anticoagulant Use and Type in Geriatric Traumatic Brain Injury Using Coagulation Parameters by Gaku FUJIWARA, Yohei OKADA, Eiichi SUEHIRO, Hiroshi YATSUSHIGE, Shin HIROTA, Shu HASEGAWA, Hiroshi KARIBE, Akihiro MIYATA, Kenya KAWAKITA, Kohei HAJI, Hideo AIHARA, Shoji YOKOBORI, Motoki INAJI, Takeshi MAEDA, Takahiro ONUKI, Kotaro OSHIO, Nobukazu KOMORIBAYASHI, Michiyasu SUZUKI, Naoto SHIOMI

“…A prediction model for the type of anticoagulant used by PT-INR and APTT was developed using machine-learning methods, and a heat map visually revealed their relationship with acceptable predictive ability. …”
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The safety and efficacy of spray cryotherapy after endoscopic sinus surgery in chronic rhinosinusitis: A systematic review of randomized controlled trials [version 2; peer review:... by Adham A. Aljariri, Ibrahim T. Abuawwad, Mohammad T. Abuawwad, Ayham R. Sara, Mohammad J. J. Taha, Obaida Falah, Abdulqadir J. Nashwan, Majed Akili, Ahmad J. Taha, Abdullah A. Elhakim

“…This review aimed to investigate the effects of spray cryotherapy (SCT) following ESS in patients with chronic rhinosinusitis. Methods Six electronic databases were searched for randomized clinical trials (RCTs). …”
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Corneal Biomechanics as a Causal Factor in Myopia and Astigmatism: Evidence from Mendelian Randomization by Pinghui Wei, PhD, Guoge Han, PhD, Qi Su, MBBS, Lanbo Jia, MBBS, Chao Xue, PhD, Yan Wang, PhD

“…Participants: Corneal biomechanical data were obtained from 97 653 European participants in the UK Biobank, whereas refractive error data were sourced from the UK Biobank and FinnGen consortia. Methods: The exposures in this study were identified as corneal biomechanical parameters, specifically corneal hysteresis (CH) and the corneal resistance factor (CRF). …”
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Zonation of Debris Cones and Talus Slopes in Aghlaghan Chay Basin (South Western Slope of Sabalan Mountain) by aghil Madadi, ata gafari, elnaz piroozi

“…The purpose of this study is Assessment and zonation Debris cones and Talus slopes. 2- Materials and Methods In this research, two methods of library and field study have been utilized to gather data and information. …”
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Comparison of the Clinical Profile of Patients with Glaucoma Between Private and Government Clinics in the Philippines by Edgar Felipe U. Leuenberger, MD, DPBO, Marie Joan Therese D. Balgos, MD, DPBO, Shalam Siao-Mariano, MD, DPBO, Denise Polly Chao-Po, MD, DPBO, Irene R. Felarca, MD, DPBO, Rainier Victor A. Covar, MD, DPBO, Nilo Vincent FlorCruz, MD, DPBO, John Mark S. De Leon, MD, DPBO, Jose Ma. D. Martinez, MD, DPBO, Joseph Anthony J. Tumbocon, MD, DPBO, Maria Imelda Yap-Veloso, MD, DPBO, Robert Edward T. Ang, MD, DPBO, James Paul S. Gomez, MD, DPBO, Noel D. Atienza, MD, DPBO

“…Objective: To describe the demographic and clinical characteristics of patients with glaucoma managed at private and government institutions in the Philippines between 2009 and 2014. Methods: A research team from two private and two government institutions in the Philippines reviewed the case records of 1246 patients seen who met the following criteria: intraocular pressure of >21 mmHg, optic nerve and nerve fiber layer abnormalities, and visual field defects. …”
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Asperulosidic acid inhibits the PI3K/Akt/NF-κB pathway to suppress endotoxin-induced uveitis by Yong Du, Jing Lu, Lujia Feng, Long Zhao, Ping Wu, Yuxia He, Linbin Zhou, Xing Wang, Hui Peng

“…IntroductionUveitis, a severe inflammatory disease affecting the uvea, is associated with visual impairment and irreversible blindness. Asperulosidic Acid (ASPA), derived from Hedyotis diffusa, is known for its notable anti-inflammatory and antioxidant characteristics.MethodsThe present study explored the potential anti-inflammatory effects and the fundamental processes of ASPA by injecting it or a placebo into the vitreous of rats with endotoxin-induced uveitis (EIU). …”
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Retrospective OCT Analysis of Sphingosine-1-Phosphate Modulator Fingolimod in Multiple Sclerosis by Wilson X. Wang, MD, MPhil, Helen Rossmiller, BS, Henok Getahun, BS, Aditya Santoki, BS, Dana C. Perantie, MPH, Robert T. Naismith, MD, Rajendra S. Apte, MD, PhD

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Clinical characteristics and surgical approach for pituitary granular cell tumors: a case series of six patients and literature review by Jun Liu, Jun Liu, Wenjun Zhang, Wenjun Zhang, Qianliang Huang, Xinyun Ye, Guanlin Huang

“…ObjectiveTo investigate the clinical characteristics and therapeutic approaches for granular cell tumors (GCT) of the neurohypophysis.Materials and methodsRetrospective case series and analyzed the clinical data of six patients with histopathologically confirmed GCT of the neurohypophysis, also conducting a simple review of relevant literature.ResultsThe median age at diagnosis for the cohort of six patients was 41.0 ± 11.73 years, with an age range of 21.8 to 52.7 years. …”
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Anxiety and depression as potential risk factors for limited pain management in patients with elderly knee osteoarthritis: a cross-lagged study by Wenhao Yang, Guangyuan Ma, Jingchi Li, Taiyuan Guan, Dingchang He, Dujiang Yang, Guoyou Wang, Hui Shi

“…Pain arises from both physiological and psychological interactions, with anxiety and depression potentially contributing as risk factors that hinder effective pain management in KOA patients. Methods Before treatment(T1), A total of 206 elderly inpatients with KOA were enrolled based on initial screening criteria. …”
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Time-dependent personalized prognostic analysis by machine learning in biochemical recurrence after radical prostatectomy: a retrospective cohort study by Kodai Sato, Shinichi Sakamoto, Shinpei Saito, Hiroki Shibata, Yasutaka Yamada, Nobuyoshi Takeuchi, Yusuke Goto, Sazuka Tomokazu, Yusuke Imamura, Tomohiko Ichikawa, Eiryo Kawakami

“…To visualize prognostic factors and assess accuracy of the time course probability, we employed SurvSHAP(t) and time-dependent Area Under Cureve(AUC). …”
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Filtration efficiency of medical and community face masks against particles carrying SARS-CoV-2 by Sara Dalvand, Rasul Nasiri, Rasoul Yarahmadi, Farah Bokharaei-Salim, Ali-Asghar Farshad, Somayeh Soleimani-Alyar

“…Hence, this study aims to assess the effectiveness of the masks in filtering airborne particulates, specifically those that carry SARSCoV-2. Materials and methods: The filtration efficiency of three types of face masks was investigated for particulate matters in a laboratory setup using a custom-designed system, including a human head mannequin and controlled aerosol injection. …”
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An anthropomorphic phantom for atrial transseptal puncture simulation training by Aya Mutaz Zeidan, Zhouyang Xu, Lisa Leung, Calum Byrne, Sachin Sabu, Yijia Zhou, Christopher Aldo Rinaldi, John Whitaker, Steven E. Williams, Jonathan Behar, Aruna Arujuna, R. James Housden, Kawal Rhode

“…This study presents a novel, patient-specific, anthropomorphic phantom for TSP simulation training that can be used with X-ray fluoroscopy and ultrasound imaging. Methods The TSP phantom was developed using additive manufacturing techniques and features a replaceable fossa ovalis (FO) component to allow for multiple punctures without replacing the entire model. …”
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Clinical Outcome of Arthroscopic Bankart Repair and Remplissage in Recurrent Anterior Shoulder Dislocation in Manual Workers by Sharma DK, Shetty P, Kumar N, Kankane A, Anant K, Jamwal R

“…The arthroscopic Bankart repair and Remplissage in treatment of recurrent anterior shoulder dislocation in manual workers has reduced recurrence rates and improved patient satisfaction. Materials and methods: A total of 36 patients underwent arthroscopic Bankart with Remplissage for recurrent anterior shoulder dislocation, enrolled between February 2022 to December 2023 considering various inclusion and exclusion criteria. …”
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A mapping of health education institutions and programs in the WHO African Region [version 1; peer review: 1 approved, 2 approved with reservations] by Arnaud Fontanet, Donald C. Cole, Christina Zarowsky, Justin Pulford, Henry A. Adeola, Pierre Abomo, Niamh Fitzgerald, Aaron N. Yarmoshuk

“…Details on the number, type and distribution of medical and health science programs offered by African higher education institutions remains scattered.  Methods: We merged and updated datasets of health professional and post-graduate programs to develop a mapping of health education institutions covering the World Health Organization African Region as of 2021. …”
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Screening for diabetic retinopathy at a health centre in South Africa: A cross-sectional study by Ntokozo Zulu, Patrick Ngassa Piotie, Elizabeth M. Webb, Wezi G. Maphenduka, Steve Cook, Paul Rheeder

“…Setting: Laudium Community Health Centre (CHC), a PHC facility in Tshwane. Methods: We conducted a cross-sectional study from February 2022 to August 2022. …”
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Patient experiences of WALANT for outpatient upper limb surgery: A cross-sectional study of perioperative pain and anxiety by Reshlan Govender, Antoine G.L. Rocher, Mario T. Rankin, Khangelani Sondovana, Simphiwe C. Phenyane, Megan O'Connor

“…This study aimed to determine patients’ anxiety and pain related to WALANT use in outpatient upper limb surgery, and to identify factors that increased the risk of heightened pain experiences. Methods: This multicentre cross-sectional study conducted between December 2022 and June 2024 utilised the ‘strengthening the reporting of observational studies in epidemiology guidelines’. …”
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Evaluation of Association between Body Dysmorphic Disorder with the Aesthetic Component of the Index of Orthodontic Treatment Need from the Perspective of Patient and Orthodontists by Houriyeh Khatami, Meisam Moradi, Reza Faraji, Manouchehr Rahmati Kamel, Seyedali Seyedmajidi, Mahjoubeh Betyar

“…Therefore, the aim of this study was to evaluate the relationship between body dysmorphic disorder and the aesthetic component of the index of orthodontic treatment need (IOTN-AC) and IOTN-AC determined by examiner (IOTN-ACE).Methods and Materials: This descriptive study was conducted on 228 eligible orthodontic patients over the age of 12. …”
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