Anterior temporal lobectomy and selective AmygdaloHippocampectomy complications across Europe: review, meta-analysis, and Delphi consensus by Maria D. Karagianni, Olaf E.M.G. Schijns, Alexandros Brotis, Anastasia Tasiou, Christian Auer, Thomas Blauwblomme, Marcelo Budke, Alexandre Rainha Campos, Santiago Candela-Cantó, Hans Clusmann, Alessandro Consales, Massimo Cossu, Daniel Delev, Christian Dorfer, Georg Dorfmüller, Arild Egge, Lorand Eröss, Sarah Ferrand-Sorbets, Flavio Giordano, Cihan Isler, Jugoslav Ivanovic, Thilo Kalbhenn, Atte Karppinen, Paivi Koroknay-Pal, Niklaus Krayenbühl, Marec von Lehe, Carlo E. Marras, Ioannis Mavridis, Daniel Nilsson, Julia Onken, Christian Raftopoulos, Michele Rizzi, Dirk van Roost, Karl Rössler, Jonathan Roth, Jordi Rumia, Alexandra Seromenho-Santos, Thomas Sauvigny, Didier Scavarda, Christian Scheiwe, Karl Schaller, Sophie Schuind, Ido Strauss, Tom Theys, Mustafa Uzan, Konstantinos N. Fountas, Franziska Schmidt, Linda Ackermans, Pedro Duarte Batista, Michael Hart, Marie Krüger

“…Research question: This study sought to gather expert European consensus on surgical strategies and complication rate for ATL and selAH, in both adult and pediatric patients. Materials and methods: A modified Delphi technique was employed, with 39 experienced epilepsy surgeons from 35 different European centers. …”
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Targeted enamel remineralization with mineral-loaded starch particlesWhy Is This Important? by Nathan A. Jones, PhD, Li-Chi Pan, MEng, Susan E. Flannagan, MS, Kai A. Jones, MD, Lyudmila Lukashova, MS, Lucas Wightman, BEng, Sywe-Ren Chang, MS, Glenn Jones, MD, Livia M.A. Tenuta, DDS, PhD, Carlos González-Cabezas, DDS, PhD, Brian H. Clarkson, DDS, PhD, Wendy Bloembergen, MD, Steven Bloembergen, PhD

“…This study shows in vitro proof-of-concept. Methods: Mineral-loaded cationic starch (MLCS) particles were prepared, containing calcium, phosphate, and fluoride to provide fluoride-plus (FP) and fluoride-free (FF) alternatives. …”
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Longitudinal study of cognitive and mental functions among adult Hodgkin-lymphoma survivors, based on data from a primary treatment center in Hungary by István Virga, István Virga, Karolina Kósa, Anna Illés, Zsófia Miltényi, Zsófia Miltényi, Tibor Ivánka, Roland Berecz, Anikó Égerházi, Árpád Illés, Árpád Illés, Ferenc Magyari, Ferenc Magyari

“…In the present longitudinal study, we measured cognitive function in our HL patients, in search of potential correlations between patient-related factors, the signs and symptoms of their diseases, and therapeutic factors.MethodsPatients underwent a computer-assisted assessment (CANTAB) of cognitive function (especially domains of visual memory, attention, working memory, and planning) and filled out psychological questionnaires (standardized, self-administered and validated for Hungarian language) before treatment (n=30, T1) and after the first-line treatment (n=25, T2), and 8.6 years after the end of chemotherapy (n=19, T3).ResultsThe median age of 16 females and 14 males was 35 years (20-69), 35 years (21-63) after chemotherapy, and 43 years (29-70) at the end of the long-term follow-up, when the study was completed. 77% of all patients showed cognitive impairment before treatment. …”
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The association between periodontal disease and adverse pregnancy outcomes: a bibliometric analysis from 2000 to 2023 by Miaomiao Zhao, Miaomiao Zhao, Haoxiang Chang, Haoxiang Chang, Yuxu Yue, Yuxu Yue, Xinyue Zeng, Xinyue Zeng, Shaobang Wu, Shaobang Wu, Xiuyun Ren, Xiuyun Ren

“…This study aimed to visualize knowledge framework and research trends concerning the relationship between periodontal disease and adverse pregnancy outcomes from 2000 to 2023 through bibliometric approaches.MethodsOn September 22, 2024, articles and reviews on the connection between periodontal disease and adverse pregnancy outcomes were retrieved from the Web of Science Core Collection (WOSCC). …”
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Effect of intensive glycemic control on the changes of diabetic retinopathy in type 2 diabetes: a prospective observational cohort study by Xinyan Wu, Yayi Yan, Yuntong Li, Yiran Fan, Lingyi Li, Ching-Kit Tsui, Kaiqun Liu, Xiaoling Liang, Wenyong Huang, Andina Hu, GDES Group

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Pulsed Low-Intensity Focused Ultrasound (LIFU) Activation of Ovarian Follicles by Yan Xiao, Lixia Yang, Yicong Wang, Yu Wang, Yuning Chen, Wenhan Lu, Zhenle Pei, Ruonan Zhang, Yao Ye, Xiaowei Ji, Suying Liu, Xi Dong, Yonghua Xu, Yi Feng

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Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids by Cécile Méjécase, Cécile Méjécase, Ya Zhou, Nicholas Owen, Pablo Soro-Barrio, Riccardo Cheloni, Riccardo Cheloni, Neelima Nair, Hajrah Sarkar, Hajrah Sarkar, Lyes Toualbi, Lyes Toualbi, Mariya Moosajee, Mariya Moosajee, Mariya Moosajee

“…Heterozygous variants in RDH12 cause a rare autosomal dominant (AD) retinitis pigmentosa.MethodsAs no disease models exist, we generated human induced pluripotent stem cell-derived retinal organoids (RO) from an RDH12-AD patient (with pathogenic variant c.759del, p.Phe254Leufs*24) alongside a healthy, unaffected control.ResultsRDH12-AD RO exhibited correct localization of RDH12 to the photoreceptor inner segments up to week 44; however, transmission electron microscopy at week 37 showed that photoreceptors were less abundant and shorter in length. …”
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Development of Bimodal Emotion Recognition System Based on Skin Temperature and Heart Rate Variability Using Hybrid Neural Networks by Sayat Orynbassar, Duygun Erol Barkana, Evan Yershov, Madiyar Nurgaliyev, Ahmet Saymbetov, Batyrbek Zholamanov, Gulbakhar Dosymbetova, Ainur Kapparova, Nursultan Koshkarbay, Nurzhigit Kuttybay, Askhat Bolatbek, Kymbat Kopbay, Dinara Almen

“…Notably, these physiological signals can be measured remotely, addressing the limitations of direct measurement methods. The integration of these modalities enables the model to effectively utilize both spatial and temporal features for robust emotion classification. …”
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An artificial intelligence accelerated ab initio molecular dynamics dataset for electrochemical interfaces by Yong-Bin Zhuang, Chang Liu, Jia-Xin Zhu, Jin-Yuan Hu, Jia-Bo Le, Jie-Qiong Li, Xiao-Jian Wen, Xue-Ting Fan, Mei Jia, Xiang-Ying Li, Ao Chen, Lang Li, Zhi-Li Lin, Wei-Hong Xu, Jun Cheng

“…Complementing experimental approaches, computational methods, such as ab initio molecular dynamics and machine learning-accelerated molecular dynamics, offer an efficient means of obtaining microscopic information. …”
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Effects of Route Complexity and Lighting on Route Following in Alzheimer’s Disease and Posterior Cortical Atrophy by Amelia M. Carton, Chris Frost, Teresa Poole, Biao Yang, Ian D. McCarthy, Tatsuto Suzuki, Catherine Holloway, Robin Serougne, Derrick Boampong, Mary Pat Sullivan, Nick Tyler, Sebastian Crutch, Keir X. X. Yong

“…This study aimed to investigate the effects of the built environment on mobility and navigation in people with dementia-related visual loss. Methods: Participants with posterior cortical atrophy (PCA; “visual-variant Alzheimer’s”; n = 11), typical Alzheimer’s disease (tAD; N = 10), and controls (n = 13) repeatedly walked down routes within a simplified real-world setting. …”
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Ayahuasca-inspired DMT/HAR formulation reduces brain differentiation between self and other faces by Dila Suay, Helena D. Aicher, Micheal Kometer, Michael J. Mueller, Luzia Caflisch, Alexandra Hempe, Camilla P. Steinhart, Claudius Elsner, Ilhui A. Wicki, Jovin Müller, Daniel Meling, Dario A. Dornbierer, Milan Scheidegger, Davide Bottari

“…Objective: This study investigates the effects of an ayahuasca-inspired novel DMT/HAR (N,N-dimethyltryptamine/Harmine) formulation and Harmine alone on face recognition and self-referential processing, as measured by event-related potentials (ERPs) and subjective behavioral measures. Methods: In a within-subject, double-blind, placebo-controlled design, 30 healthy male participants underwent EEG recording during a visual oddball task involving Self, Familiar, and Unknown Faces. …”
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PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease by Yixian Ma, Yixian Ma, Yixian Ma, Jinshan Suo, Siqi Sheng, Siqi Sheng, Siqi Sheng, Ling Chen, Ling Chen, Ling Chen, Ling Chen

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Adalimumab vs placebo as add-on to Standard Therapy for autoimmune Uveitis: Tolerability, Effectiveness and cost-effectiveness—a protocol for a randomised controlled trial (ASTUTE... by Chris A Rogers, Andrew Dick, Tunde Peto, Robert Wilson, Pearse A Keane, Alastair K Denniston, Srilakshmi M Sharma, Lucy Culliford, Katie Pike, Sarah Baos, Carlos Pavesio, Sarah Wordsworth, Barnaby Reeves, Annie Folkard, Mae Hazell, Mandy P Y Lui, Nicholas A V Beare

“…Secondary outcomes include individual TF components, retinal morphology, adverse events, health-related quality of life, patient-reported side effects and visual function, best-corrected visual acuity, employment status and resource use. …”
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Course of uveitis in children with juvenile idiopathic arthritis (JIA): Five years follow-up data from a prospective multicenter Inception Cohort of Newly diagnosed patients with J... by Karoline Baquet-Walscheid, Kirsten Minden, Martina Niewerth, Frank Dressler, Ivan Foeldvari, Dirk Foell, Johannes-Peter Haas, Gerd Horneff, Anton Hospach, Tilmann Kallinich, Jasmin Kümmerle-Deschner, Kirsten Mönkemöller, Christoph Tappeiner, Daniel Windschall, Jens Klotsche, Arnd Heiligenhaus

“…The present study assesses the 5-years outcome of JIAU by analyzing data from a prospective study initiated in 2010. Methods Data from 75 patients with onset of uveitis after study enrollment, and with a documentation at 5-years follow-up (5yFU) were available for analysis of uveitis characteristics, frequency and predictors of „inactivity on medication “ (defined as inactive uveitis for ≥ 6 months) and „inactivity off medication “ (defined as inactive uveitis for ≥ 6 months off medication). …”
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Effects of repeated low-level red-light therapy on macular retinal thickness and microvascular system in children with myopia by Linlin Liu, Yuchuan Wang, Fang Liu, Xinghui Yu, Lianfeng Xie, Shuxiang Tan, Jing Liu, Yanfang Liu, Jiaxing Huang, Shuang Zhang, Yiping Jiang

“…Objective: The objective of the study was to use optical coherence tomography angiography (OCTA) to analyze the effects of repeated low-level red-light (LLLT) therapy on macular retinal thickness and the microvascular system in children with myopia to evaluate the safety of this therapy. Methods: This prospective study included 40 school-age children with myopia (80 eyes), aged 7–14 years, who received therapy using a LLLT instrument. …”
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Prefrontal cortex activity during binocular color fusion and rivalry: an fNIRS study by Xiang Liu, Xiang Liu, Xiang Liu, Xuesong Jin, Xuesong Jin, Lijun Yun, Lijun Yun, Zaiqing Chen, Zaiqing Chen, Zaiqing Chen, Zaiqing Chen

“…Binocular color fusion and rivalry, which involve advanced cognitive functions in the prefrontal cortex (PFC), provide a unique perspective for exploring brain activity.MethodsThis study used functional near-infrared spectroscopy (fNIRS) to examine PFC activity during binocular color fusion and rivalry conditions. …”
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The association between myopia and mental health among Chinese children in primary and secondary school: a cross-sectional study by Shijie Yu, Hongpo Yin, Wei Sun, Ruosong Yang, Ronghua Lai, Yushan Yu, Hongsheng Bi, Hongsheng Bi, Jianfeng Wu, Jianfeng Wu, Jianfeng Wu

“…ObjectiveThis study aimed to investigate the association between myopia and mental health among Chinese children in primary and secondary school.MethodsThis study employed a cross-sectional study design, including 1,640 children and their parents, via an online survey. …”
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Protocol to test the efficacy and safety of frequent applications of skin electrical stimulation for Leber hereditary optic neuropathy: a single-arm, open-label, non-randomised pro... by Sotaro Mori, Yusuke Murai, Kaori Ueda, Mari Sakamoto, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura, Takayuki Nagai, Fumio Takano

“…In the present study, we will examine the magnitude and persistence of the efficacy and presence or absence of adverse events using SES with a more frequent stimulation protocol.Methods and analysis This study will be a single-arm, open-labelled, non-randomised clinical study that analyses 15 cases of LHON with G11778A mutation. …”
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Monitoring of Separate Pathogenetically Significant Biochemical Markers in Lacrimal Fluid, Ophthalmological Parameters with Combined Pathology of Diabetic Retinopathy and Age-Relat... by I. V. Vorobyeva

“…Object: Optimization of treatment in early stages of combined fundus pathology diabetic retinopathy (DR without DME) and dry type of age-related macular degeneration (AMD AREDS I, II, III).Patients and methods: 120 people (150 eyes). Study group 1 (SG1) — control 60 people. (60 eyes); study group 2 (SG2) — 30  people. (30 eyes) — DRI without DME and AMD AREDS I, II, III)  treatment: 1 year with angioprotective calcium dobezilate (Doxi- Hem®) dose of 500 mg 3 after 6 months, 500 mg once a day for 6  months and at the same time 1 year antioxidant agent (Retinorm) 1  capsule 3 times a day; study group 3 group (SG3) 30 people. (30  eyes) — with DRO and dry type of AMD (AREDS I, II, III) 1 year  Retinorm 1 capsule 3 times a day; study group 4 (SG4) with DRI  without DME — 30 people. (30 eyes) 1 year Doxi-Hem®. …”
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A Comparative Study on the Prevalence of Helicobacter pylori Infection in Patients with Central Serous Chorioretinopathy versus a Control Population by Saad EME, Mohammed HEM, Ibrahim MMA, Abdhafez SME, Selim OHS, Tawfik AMR, Abbass AME, Alabshihy MSI, Ayoub AAA, Ghazala AMA, Abdelmaged WKA

“…Post-treatment evaluation showed improved visual acuity and reduced recurrence rates in Group A patients who received H. pylori eradication therapy. …”
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