Complex and severe infection in a 67-year-old liver transplant recipient due to Cunninghamella elegans, Bordetella bronchiseptica, and Pneumocystis jirovecii by Muyun Wei, Kangyi Gu, Juanxiu Qin, Xinhua Lu, Junqi Feng, Shaowei Mao, Min Li, Zhilan Li, Changsheng Wang

“…Also, the case indicates that traditional methods are insufficient for the etiological diagnosis needs of critical and severe patient populations, and timely use of mNGS should be recommended.…”
Get full text

Extract of Tangerine Peel as a Botanical Insecticide Candidate for Smallholder Potato Cultivation by José-Manuel Pais-Chanfrau, Lisbeth J. Quiñonez-Montaño, Jimmy Núñez-Pérez, Julia K. Prado-Beltrán, Magali Cañarejo-Antamba, Jhomaira L. Burbano-García, Andrea J. Chiliquinga-Quispe, Hortensia M. Rodríguez Cabrera

“…Researchers are now exploring natural, eco-friendly alternatives for pest control. Methods: This study evaluated two ethanol-based formulations (1.25% and 2.50%, <i>v</i>/<i>v</i>) derived from the tangerine peel (<i>Citrus reticulata</i> L. var. …”
Get full text

Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies by Katherine Chong, Madisan Chavez, Ave Dersch, John Doyle, Margaret Eggers, JoRee LaFrance, Myra J Lefthand, Findlay MacDermid, Claire McAuley, Vanessa Simonds, Sara L Young, Niladri Basu

“…Conventional human health risk assessment (HHRA) methods do not account for these unique contexts. …”
Get full text

Cytoskeleton imaging of colorectal and lung cancer spheroids using light sheet microscopy by Sonia Prado-López, Massih Foroughipour, Klaus Becker, Seyed Meraaj Foroughipour, Lukas Weber, Heinz Wanzenboeck, Nika Sarem, Saiedeh Saghafi

“…To date, studies of actin dynamics in cancer cells have primarily relied on simplistic 2D models and fluorescence microscopy. Methods In this paper, we propose combining light sheet fluorescence microscopy (LSFM) with colorectal cancer (CRC) and non-small cell lung carcinoma (NSCLC) spheroids to study F-actin distribution and exposition with minimal distortions. …”
Get full text

Assessment of location and anatomical characteristics of lingual foramen using cone beam computed tomography by Veličković Stefan, Matijević Stevo, Jovičić Bojan, Bubalo Marija, Stevanović Momir, Vasović Miroslav

“…The aim of this study was to assess the location and anatomical characteristics of LF using cone beam computed tomography (CBCT). Methods. The research was designed as a retrospective study in which 99 CBCT scans were analyzed. …”
Get full text

Sensory innervation in the prostate and a role for calcitonin gene-related peptide in prostatic epithelial proliferation by Hanyu Xia, Hanyu Xia, Travis J. Jerde, Travis J. Jerde, Jill C. Fehrenbacher, Jill C. Fehrenbacher, Jill C. Fehrenbacher, Jill C. Fehrenbacher

“…Recent studies have highlighted a role for sensory nerves beyond perception of noxious stimuli, as anterograde release of neuropeptides from sensory nerves can affect vascular tone and local immune responses.MethodsTo identify the degree of sensory innervation in the prostate, we utilized state-of-the-art tissue clearing and microscopy to visualize sensory innervation in the different lobes of the mouse prostate. …”
Get full text

Indoor endotoxin and house dust mite concentrations in the canine homologue of human atopic dermatitis by Yunji Song, Yeji Kim, Jihyun Kim, Ha-Jung Kim

“…The aim of this study is to analyze the effects of HDM and endotoxin concentrations on AD in dogs and compare their immunological profiles with humans. Methods: We graded the canine AD Extent and Severity Index-4 (CADESI-4), Pruritus Visual Analogue Scale (PVAS), and transepidermal water loss (TEWL) in dogs with (n = 42) and without AD (controls; n = 18). …”
Get full text

O-arm navigation-based transforaminal unilateral biportal endoscopic discectomy for upper lumbar disc herniation: an innovative preliminary study by Dong Hyun Lee, Choon Keun Park, Jin-Sung Kim, Jin Sub Hwang, Jin Young Lee, Dong-Geun Lee, Jae-Won Jang, Jun Yong Kim, Yong-Eun Cho, Dong Chan Lee

“…Methods The UBE approach targeted the ventral part of the superior articular process in the transforaminal UBE setup, specifically for upper lumbar disc herniation, with an approach angle of approximately 30º on the axial plane. …”
Get full text

Comparison of effect and mechanism between nalfurafine hydrochloride and narrow-band ultraviolet B phototherapy in the treatment of pruritus in hemodialysis patients by Sooyeon Choi, Dong Hui Shin, Jae-Seok Kim, Jun Young Lee, Seung Ok Choi, Byoung-Geun Han, Eun Jung Kim, Eung-Ho Choi, Jae Won Yang

“…We aim to compare newly developed Nalfuranfine HCL, kappa-opioid receptor agonist, with NB-UVB in HDP.Methods Twenty HDP were enrolled from Wonju severance Christian hospital. …”
Get full text

Structural Retinal and Optic Nerve Changes in Prostate Cancer Patients Receiving Androgen Receptor Pathway Inhibitors: An OCT-Based In Vivo Analysis by Yasemin Bakkal Temi, Büşra Yılmaz Tuğan, İlkay Çıtakkul, Ece Baydar, Gözde Karaca, Sibel Balcı, Devrim Çabuk, Umut Kefeli, Nurşen Yüksel, Kazım Uygun

“…No significant differences were observed between groups in terms of age, visual acuity, intraocular pressure, central corneal thickness, or lens status. …”
Get full text

Induced zero-phase synchronization as a potential neural code for optimized visuomotor integration by Kirstin-Friederike Heise, Geneviève Albouy, Nina Dolfen, Ronald Peeters, Dante Mantini, Stephan P. Swinnen

“…Our goal was to probe the effect of phase entrainment of the sensorimotor mu-rhythm on visuomotor integration. Methods: Participants received transcranial alternating current stimulation over bilateral motor cortices (M1) while performing a visually-guided force adjustment task during functional magnetic resonance imaging. …”
Get full text

Structural-functional connectivity decoupling in multiscale brain networks in Parkinson’s disease by Ting Zou, Chen Chen, Huafu Chen, Xuyang Wang, Lin Gan, Chong Wang, Qing Gao, Chunyan Zhang, Wei Liao, Jingliang Cheng, Rong Li

“…However, the structural-functional (SC-FC) coupling changes in combination with subcortical regions at the network level are rarely investigated in PD. Methods SC-FC coupling networks were systematically constructed using the structural connectivity obtained by diffusion tensor imaging and the functional connectivity obtained by resting-state functional magnetic resonance imaging in 53 PD and 72 age- and sex-matched healthy controls (HCs). …”
Get full text

Ecological monitoring of invasive species through deep learning-based object detection by Xinwu Ji, Yang Zhang, Jiaquan Wan, Tao Yang, Qiong Yang, Jiaqing Liao

“…However, traditional monitoring methods, such as manual inspection and remote sensing, often struggle with limited scalability, accuracy, and adaptability in complex natural environments. …”
Get full text

Analysis of safety of postoperative accelerated hypofractionated radiotherapy for patients with stage I-IIIA breast cancer by G. V. Afonin, I. A. Gulidov, Y. A. Ragulin, E. E. Beketov, S. V. Gamayunov, А. A. Zharikov, S. A. Ivanov, A. D. Kaprin

“…Aim: to conduct a comparative analysis of the safety of postoperative accelerated hypofractionated radiotherapy for patients with stage I-IIIA breast cancer.Material and Methods. From 2013 to 201, 316 patients with stage I-IIIA breast cancer were treated at A.F. …”
Get full text

A prospective, multicenter, randomized, double-blind placebo-controlled trial on purified and specific Cytoplasmic pollen extract for hot flashes in breast cancer survivors by Valentina Elisabetta Bounous, Isabella Cipullo, Marta D’Alonzo, Silvia Martella, Dorella Franchi, Paola Villa, Nicoletta Biglia, Annamaria Ferrero

“…Objective evaluate the efficacy and tolerability of PureCyTonin against hot flashes (HF) in breast cancer survivors (BCS).Methods a prospective, multicenter, randomized, double-blind placebo-controlled trial was conducted in Italy.Interventions administration of PureCyTonin or placebo, for 3 months. …”
Get full text

Opportunities for Laboratory Testing to Inform Antimicrobial Use for Bovine Respiratory Disease: Application of Information Quality Value Stream Maps in Commercial Feedlots by Simon J. G. Otto, Colleen M. Pollock, Jo-Anne Relf-Eckstein, Lianne McLeod, Cheryl L. Waldner

“…Conclusions: The IQ-VSMs provided a valuable framework to visualize the integration of BRD pathogen and AMR laboratory data to support AMS and address any potential future testing requirements.…”
Get full text

Novel GUCY2D Gene Mutations in Japanese Male Twins with Leber Congenital Amaurosis by Katsuhiro Hosono, Yuko Harada, Kentaro Kurata, Akiko Hikoya, Miho Sato, Shinsei Minoshima, Yoshihiro Hotta

“…This study was conducted to investigate genetic and clinical features of LCA in a set of Japanese male twins with LCA. Methods. To identify causative mutations, 74 genes known to cause RP or LCA were examined by targeted-next generation sequencing (NGS). …”
Get full text

Effects of Home-Based Hand Exercises on Pain and Function in Patients with Hand Osteoarthritis by Alireza Sadeghi, Iraj Alibiglou, Khadije Jozmoghadam, Tayyebeh Lakzaei, Arezoo Karimimoghaddam, Alireza Zeraatchi, Zhaleh Karimimoghaddam, Mahnaz Ghaebi

“…We set out to investigate whether hand exercise leads to a clinically important change in hand pain, and its function. Methods: A total of 40 patients over 40 years of age whose hand OA was confirmed by the American College of Rheumatology (ACR) criteria, were divided into control and intervention groups and filled the visual analogue scale (VAS) and the Functional Index for Hand Osteoarthritis (FIHOA) questionnaires. 4 weeks of physical hand exercise at home was performed by the intervention group and the control group was assigned to waiting list and the indices were recorded again. …”
Get full text

The Comparison of the Surgical Outcome for the Full-Thickness Macular Hole with/without Lamellar Hole-Associated Epiretinal Proliferation by Yuri Ubukata, Hisanori Imai, Keiko Otsuka, Masaya Nishizaki, Rumiko Hara, Mamoru Uenishi, Atsushi Azumi, Makoto Nakamura

“…To compare the surgical outcome of pars plana vitrectomy (PPV) for full-thickness macular hole (FTMH) with and without lamellar hole-associated epiretinal proliferation (LHEP). Methods. This retrospective study included 158 eyes of 158 patients with FTMH treated with PPV. …”
Get full text

Bowel movement alterations predict the severity of diverticular disease and the risk of acute diverticulitis: a prospective, international study by Antonio Tursi, Daniele Piovani, Giovanni Brandimarte, Francesco Di Mario, Walter Elisei, Marcello Picchio, Gisella Figlioli, Gabrio Bassotti, Leonardo Allegretta, Maria Laura Annunziata, Mauro Bafutto, Maria Antonia Bianco, Raffaele Colucci, Rita Conigliaro, Dan L. Dumitrascu, Ricardo Escalante, Luciano Ferrini, Giacomo Forti, Marilisa Franceschi, Maria Giovanna Graziani, Frank Lammert, Giovanni Latella, Daniele Lisi, Giovanni Maconi, Debora Compare, Gerardo Nardone, Lucia Camara de Castro Oliveira, Chaves Oliveira Enio, Savvas Papagrigoriadis, Anna Pietrzak, Stefano Pontone, Ieva Stundiene, Tomas Poškus, Giuseppe Pranzo, Matthias Christian Reichert, Stefano Rodino, Jaroslaw Regula, Giuseppe Scaccianoce, Franco Scaldaferri, Roberto Vassallo, Costantino Zampaletta, Angelo Zullo, Erasmo Spaziani, Stefanos Bonovas, Alfredo Papa, Silvio Danese

“…A 10-point visual analog scale (VAS) was used to assess the severity of constipation and diarrhea. …”
Get full text