AlgaeOrtho, a bioinformatics tool for processing ortholog inference results in algae by Mary-Francis LaPorte, Neha Arora, Struan Clark, Ambarish Nag

“…Although bioinformatics tools for the identification of protein orthologs already exist, processing the output from such tools is nontrivial, especially for a researcher with little or no bioinformatics experience.MethodsThe present study introduces AlgaeOrtho, a user-friendly tool that builds upon the SonicParanoid orthology inference tool (based on an algorithm that identifies potential protein orthologs based on amino acid sequences) and the PhycoCosm database from JGI (Joint Genome Institute) to help researchers identify orthologs of their proteins of interest in multiple diverse algal species.ResultsThe output of this application includes a table of the putative orthologs of their protein of interest, a heatmap showing sequence similarity (%), and an unrooted tree of the putative protein orthologs. …”
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Reverse shoulder joint replacement in rheumatoid arthritis: medium-term results in 37 patients by M. A. Makarov, A. A. Roskidailo, M. V. Panteleev

“…Objective: to assess functional results and quality of life in patients with rheumatoid arthritis (RA) after reverse shoulder joint replacement.Patients and methods. Examinations were made in 37 patients with RA involving the shoulder joint, who underwent shoulder joint replacement using a reverse DeltaX-tend DePuy prosthesis in 2006–2017. …”
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Systematic review on barriers and enablers for access to diabetic retinopathy screening services in different income settings. by Mapa Mudiyanselage Prabhath Nishantha Piyasena, Gudlavalleti Venkata S Murthy, Jennifer L Y Yip, Clare Gilbert, Maria Zuurmond, Tunde Peto, Iris Gordon, Suwin Hewage, Sureshkumar Kamalakannan, Sureshkumar Kamalakannan

“…<h4>Background</h4>Diabetic retinopathy (DR) can lead to visual impairment and blindness if not detected and treated in time. …”
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The Effect of Aromatherapy on Pain and Anxiety Levels Before Breast Biopsy: A Randomized Controlled Trial by Ezgi Hancı, Yasemin Uslu, Erkin Arıbal

“…This randomized controlled trial evaluated the effectiveness of lavender and lavender-peppermint aromatherapy before breast biopsy for reducing women’s pain and anxiety. Materials and Methods: This trial was conducted in the breast outpatient clinic of a university hospital in İstanbul between July 2021 and March 2023. …”
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Management and safety of same day bilateral intravitreal anti-VEGF injections in a treat-and-extend regimen by Christina Plasencia, Jonas Eschle, Katja Hatz

“…This study evaluates the safety and management of bilateral same day anti-VEGF injections within a treat-and-extend regimen (TER) and proposes a clinical guideline for coordination of bilateral treatment. Methods This retrospective observational study analysed electronic health records of 428 included patients treated bilaterally with ranibizumab 0.5mg or aflibercept 2mg at the VISTA Augenklinik (Binningen, Switzerland) between 2015 and 2019. …”
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SPECIES COMPOSITION, STRUCTURE AND CARBON STOCKS OF DEADWOOD OF THE «KOLOGRIVSKY LES» NATURE RESERVE FORESTS AFTER THE CATASTROPHIC WINDTHROW OF 2021 by A. V. Lebedev, N. V. Ivanova, D. Yu. Gosteva, V. V. Gostev, I. G. Krinitsyn, M. P. Shashkov

“…Three different ways for the deadwood carbon stock evaluation on transects were used. These methods were based on the basic wood density at different stages of decomposition and how the carbon content in deadwood changes with its volume. …”
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Factors Affecting Ray Trace LASIK Data Acquisition in Clinical Practice: Options for Addressing Accommodation by Thananjeyan AL, Bala C

“…Akshaya L Thananjeyan,1,2 Chandra Bala1 1PersonalEyes, Sydney, NSW, Australia; 2Emergency Department, Sydney Hand and Eye Hospital, Sydney, NSW, AustraliaCorrespondence: Chandra Bala, PersonalEyes, Sydney, NSW, Australia, Tel +61 88337111, Email bala@personaleyes.com.auPurpose: To assess factors affecting successful data acquisition for InnovEyes guided ray trace LASIK.Setting: Single-site ophthalmology practice.Design: Retrospective review.Methods: A total of 1283 eyes with myopia and myopic astigmatism were assessed over 18-months for ray trace-based LASIK planning. …”
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Minimally invasive surgical treatment for temporomandibular joint in patients with various rheumatic diseases by A. Yu. Drobyshev, I. D. Zaslavsky, T. V. Dubinina, A. N. Kuznetsov, D. V. Shipika

“…Objective: to evaluate the efficiency of minimally invasive surgical interventions (TMJ arthrocentesis and arthroscopy) in patients with RDs. Patients and methods. The investigation enrolled 64 patients with different RDs (43 with rheumatoid arthritis, 11 with psoriatic arthritis, 8 with systemic lupus erythematosus, and 2 with ankylosing spondylitis) who were divided into three groups in relation to the severity of TMJ involvement in accordance with the Wilkes classification. …”
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The role of clinical parameters and cathepsin S gene expression in predicting the development of postoperative pain in patients with hip osteoarthritis by E. V. Chetina, K. E. Glemba, G. A. Markova, A. P. Prizov, M. A. Makarov

“…Objective: to evaluate the significance of clinical indicators, expression of pain syndrome genes cathepsin S and pro-inflammatory cytokines in peripheral blood for predicting the development of postoperative pain (POP)  in patients with hip osteoarthritis (HOA) before total arthroplasty (TA).Material and methods. The study included 31 patients with stages III–IV of HOA (mean age 61.3±9.8 years) who underwent TA and 26 healthy volunteers (control group). …”
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Minimally Invasive Discectomy and Decompression for Lumbar Spine using Tubular Retractor System: Technique, Learning Curve and Outcomes by V A Kumar, Ramanadha Reddy, Vamsi Krishna Yerramneni, Swapnil Kolpakawar, K.S. Vishwa Kumar, Patlolla Pratyusha

“…Objective To study the indications, technical nuances, learning curve, and outcomes associated with minimally invasive tubular discectomy of spine (MITDS) and minimally invasive tubular decompression (MITD) using the tubular retractor system and compare the outcomes with open microdiscectomy and open decompression. Materials and Methods All patients who underwent MITDS and MITD received a trial of conservative management for 6 weeks prior to surgery. …”
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Soil Quality Indexing Strategies for Evaluating Sugarcane Expansion in Brazil. by Maurício R Cherubin, Douglas L Karlen, Carlos E P Cerri, André L C Franco, Cássio A Tormena, Christian A Davies, Carlos C Cerri

“…Weighted and non-weighted additive methods were used to combine individual indicator scores into an overall SQI. …”
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Neurocognition as a major predictor of 8-week response to antipsychotics for drug-naïve first-episode schizophrenia using machine learning by Xianghe Wang, Tianqi Gao, Xiaodong Guo, Bingjie Huang, Yunfei Ji, Wanheng Hu, Xiaolin Yin, Yue Zheng, Chengcheng Pu, Xin Yu

“…However, it is unclear whether neurocognitive dysfunction can predict the efficacy of antipsychotics for first-episode schizophrenia (FES). Machine learning methods provide a relatively unbiased approach when evaluating heterogeneous data, especially when building multifactor prediction models. …”
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Machine learning-based prediction of the necessity for the surgical treatment of distal radius fractures by Jongmin Lim, Sehun Chang, Kwangsu Kim, Hee Jin Park, Eugene Kim, Seok Woo Hong

“…This study aimed to develop a machine learning (ML) model that determines the need for surgical treatment in patients with DRFs using a ML model that incorporates various clinical data concatenated with plain radiographs in the anteroposterior and lateral views. Methods Radiographic and clinical data from 1,139 patients were collected and used to train the ML models. …”
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Periorbital necrotizing fasciitis: the Manchester experience by Abigail Hopkins, Jonathan K. Y. Ng, Jae Yee Ku, Adam Bull, Qistina Pilson, Anne Cook

“…Five of these patients were contactable and gave informed consent for inclusion in the study. Methods Retrospective review of patient characteristics, risk factors, clinical findings, Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score, imaging results, microbiology and histology results, patient management and mortality. …”
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The effect of cognitive function heterogeneity on depression risk in older adults: a stratified analysis based on functional status by Taotao Zhang, Shang Li, Zhichen Zhu, Kexin Sha, Yuwen Liu

“…This study aimed to reveal the heterogeneity of cognitive functioning in older adults under different physical functional states through latent profile analysis (LPA) and to explore the patterns associated with depressive symptoms.MethodsBased on the China Health and Retirement Longitudinal Study (CHARLS) 2020 data, 4,158 older adults ≥60 years old were included, and the subtypes of cognitive functions (immediate memory, delayed memory, calculative ability, orientation, and visual construction) were classified by LPA. …”
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The Association of Social Determinants of Health and Patient-Reported Outcomes In Patients with Surgical Treatment of Osteochondral Lesion of the Talus by Henri Ullmann BSc, Soheil Ashkani-Esfahani MD, Alireza Ebrahimi MD, Noopur Ranganathan BS, Lorena Bejarano-Pineda MD, John Y. Kwon MD, Daniel Guss MD, MBA, Gino M M.M.J. Kerkhoffs MD, PhD, Christopher W. DiGiovanni MD, Gregory Waryasz MD

“…The effect of social determinants of health (SDOH) on treatment outcomes of this patient population has rarely been investigated to date. Methods: Patients with OLT who were 18 years of age and older and underwent operative treatment, with at least one patient-reported outcome and SDOH data available, were included. …”
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Pilot Programme for Keratoconus Screening and Management in Adolescents with Down Syndrome by Barry Power, Kirk A. J. Stephenson, Diana Malata, Conor Murphy, Barry Quill, Fiona McGrane, Eleanor Molloy, William Power

“…<b>Background/Objectives</b>: To screen a group of adolescents with Down Syndrome (Trisomy 21) for keratoconus and assess the feasibility of setting up a national screening service. <b>Methods</b>: Twenty-seven patients with Down Syndrome between 9 and 18 years of age attended our pilot keratoconus screening clinic. …”
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Metformin for knee osteoarthritis with obesity: study protocol for a randomised, double-blind, placebo-controlled trial by Yuanyuan Wang, Flavia M Cicuttini, Stephane Heritier, Mahnuma Mahfuz Estee, Anita E Wluka, Yuan Z Lim, Donna M. Urquhart

“…The aim of this randomised, double-blind, placebo-controlled trial is to determine whether metformin reduces knee pain over 6 months in individuals with symptomatic knee OA who are overweight or obese.Methods and analysis One hundred and two participants with symptomatic knee OA and overweight or obesity will be recruited from the community in Melbourne, Australia, and randomly allocated in a 1:1 ratio to receive either metformin 2 g or identical placebo daily for 6 months. …”
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Comparison of short-term effectiveness between unilateral biportal endoscopic and MED-assisted transforaminal lumbar interbody fusion for mild single-segment lumbar spondylolisthes... by Yu He, Jin-wang Liu, Miao Fang, Ming-juan He, Ding Hu, Xiao-ping Xu

“…Abstract Objectives The purpose of this study was to compare the short-term clinical efficacy of unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) versus minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) with microendoscopic discectomy (MED) for lumbar spondylolisthesis. Methods The patients were divided into MIS-TLIF group and UBE-TLIF group according to the surgical procedures. …”
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Retinal structure and related factors in 8-year-old Japanese children: The Yamanashi adjunct study of the Japan Environment and Children's Study. by Ryo Harada, Mingxue Bao, Natsuki Okabe, Yuka Kasai, Airi Takahashi, Chio Kuleshov, Yumi Shigemoto, Tadao Ooka, Hiroshi Yokomichi, Kunio Miyake, Reiji Kojima, Ryoji Shinohara, Hideki Yui, Sanae Otawa, Anna Kobayashi, Megumi Kushima, Zentaro Yamagata, Kenji Kashiwagi, Yamanashi Adjunct Study of the Japan Environment and Children’s Study Group

“…<h4>Purpose</h4>The purpose of this study was to investigate the relationships among retinal/choroidal structures and associated factors in 8-year-old Japanese children who participated in the Yamanashi Adjunct Study of the Japan Environment and Children's Study (JECS).<h4>Methods</h4>This was a study of 557 8-year-old Japanese children (274 boys, 283 girls) who participated in the JECS at the University of Yamanashi from June 2021 to March 2022. …”
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