Corneal stromal lenticule transplantation for covering macular hole during vitrectomy by Wen-Ting Ding, Yi-Le Xu, Di Li, Xiao-Xiao Qian, Jian Li, Hong-Wei Ge, Xiao-Hua Zhang, Ren-Jian Hu, Yong-Ping Hu

“…AIM: To describe an innovative surgical technique for pathologic myopia and macular holes accompanied by retinal detachment using allogeneic corneal stromal lenticule transplantation combined with pars plana vitrectomy. METHODS: The allogeneic corneal stromal lenticule was harvested through small incision lenticule extraction (SMILE) and stored at -30°C in advance. …”
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Green synthesis of silver-chitosan nanocomposite exhibits promising antibiofilm properties against pathogenic bacteria Escherichia coli and Staphylococcus aureus by Subhransu Sekhar Behera, Amrito Ghosh Majumdar, Himansu Gullani, Arka Lodh Roy, Aruna Kumar Dash, Pratyush Kumar Behera, Zahra Parwez, Seemon Giri, Priti S. Mohanty, Lopamudra Ray

“…The green synthesis of silver-chitosan nanocomposite (AgCs) is a promising avenue in nanobiotechnology, offering eco-friendly production methods and multifunctional properties. This study elucidates the green synthesis of AgNp through a sustainable approach using Streptomyces griseoincarnatus RB7AG. …”
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CatSkill: Artificial Intelligence-Based Metrics for the Assessment of Surgical Skill Level from Intraoperative Cataract Surgery Video Recordings by Binh Duong Giap, PhD, Dena Ballouz, MD, Karthik Srinivasan, MD, MS, Jefferson Lustre, BS, Keely Likosky, BS, Ossama Mahmoud, MD, Shahzad I. Mian, MD, Bradford L. Tannen, MD, JD, Nambi Nallasamy, MD

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The Therapeutic Effect of Combination of Orbital Decompression Surgery and Methylprednisolone Pulse Therapy on Patients with Bilateral Dysthyroid Optic Neuropathy by Jianan Xu, Huijing Ye, Guo Chen, Jingqiao Chen, Rongxin Chen, Huasheng Yang

“…Visual field and visual evoked potential (VEP) tests were also performed. …”
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Provider Education about Glaucoma and Glaucoma Medications during Videotaped Medical Visits by Betsy Sleath, Susan J. Blalock, Delesha M. Carpenter, Kelly W. Muir, Robyn Sayner, Scott Lawrence, Annette L. Giangiacomo, Mary Elizabeth Hartnett, Gail Tudor, Jason Goldsmith, Alan L. Robin

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Dall-E in hand surgery: Exploring the utility of ChatGPT image generation by Daniel Soroudi, Daniel S. Rouhani, Alap Patel, Ryan Sadjadi, Reta Behnam-Hanona, Nicholas C. Oleck, Israel Falade, Merisa Piper, Scott L. Hansen

“…This study explores the capabilities and limitations of these tools in hand surgery, focusing on their application in patient and medical education. Methods: Utilizing Google Trends data, common search terms were identified and queried on ChatGPT-4.5 and ChatGPT-3.5 from the following categories: “Hand Anatomy”, “Hand Fracture”, “Hand Joint Injury”, “Hand Tumor”, and “Hand Dislocation”. …”
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Methodology for adapting a co-created early childhood development intervention and implementation strategies for use by frontline workers in India and Guatemala: a systematic appli... by Amruta Bandal, Sara Hernández, Revan Mustafa, Karyn Choy, Namrata Edwards, Magdalena Guarchaj, Marinés Mejía Alvarez, Anushree Sane, Scott Tschida, Chetna Maliye, Ann Miller, Abhishek Raut, Roopa Srinivasan, Morgan Turner, Bradley H. Wagenaar, Ilgi Ertem, Maria del Pilar Grazioso, Subodh S. Gupta, Vibha Krishnamurthy, Peter Rohloff

“…There is little evidence on optimizing the effectiveness and implementation of evidence-based early childhood development (ECD) interventions when task-shifted to frontline workers. In this Methods Forum paper, we describe our adaptation of the International Guide for Monitoring Child Development (GMCD) for task-shifting to frontline workers in Guatemala and India. …”
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Selective otolithic dysfunction in patients presenting with acute spontaneous vertigo: consideration based on MRI by Keun-Tae Kim, Sangeun Park, Sun-Uk Lee, Sun-Uk Lee, Euyhyun Park, Euyhyun Park, Byungjun Kim, Ji-Soo Kim, Ji-Soo Kim

“…Herein, we report patients presenting with acute vestibular syndrome (AVS) showing selective otolithic dysfunction in the presence of normal caloric and video-HITs and abnormal enhancement of the peripheral vestibular structures on MRI.MethodsWe retrospectively reviewed the medical records of patients presenting with AVS between September 2019 and April 2024 at a tertiary referral hospital in South Korea. …”
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Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial by Vinicius Campos Bergamo, Luis Filipe Nakayama, Nilva Simeren Bueno de Moraes, Ivan Maynart Tavares, Mauro Silveira De Queiroz Campos, Ana Luisa Hofling-Lima, Maurício Maia

“…This study aimed to compare PPV followed by intravitreal antibiotic injection at the end of surgery (PPV + IVAIES) with intravitreal antibiotic injection alone (IVAI) in managing PSE. Methods This randomized clinical trial included 35 pseudophakic patients with PSE following cataract extraction, anti-vascular endothelial growth factor (anti-VEGF) injections, or glaucoma surgeries. …”
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Ultrasound and single‐port laparoscopic‐guided microwave ablation of abdominal wall endometriosis lesions: A single‐center observational study by Shunshi Yang, Jueying Li, Jingjing Li, Xiaoyu Zhao, Mengying Li, Yi Zhang, Xiong Li, Ying Chen

“…The adverse events and complications were Common Terminology Criteria for Adverse Events grade 1 or Society of Interventional Radiology classification grade A. Material and Methods This historical study included 30 patients with abdominal wall endometriosis who underwent ultrasound and single‐port laparoscopic‐guided microwave ablation at the Ultrasonography and Gynecology Department of the Wuhan Central Hospital between October 2017 and February 2022. …”
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Features of pathological changes of fibro-cartilaginous tissue knee in patients with Baker cyst by S. A. Chernyad'ev, A. I. Chernookov, E. A. Grebenev, N. I. Sivkova, A. V. Zhilyakov, D. A. Babushkin, N. Yu. Korobova, O. A. Vinogradov

“…Objective: using magnetic resonance imaging (MRI) to evaluate the characteristics of pathological changes of fibro-cartilage of the knee in patients with Baker cyst, to assess the compliance of degrees of damage stages of osteoarthritis on a scale of Kellgren–Lawrence (K–L), and compare the results with the data of other researchers.Material and methods. This study included patients (38–82 years) with a cyst Baker accidentally detected during ultrasound veins of the lower extremities. …”
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Predictive factors for response to viscosupplementation in patients with knee osteoarthritis: an analysis of clinical and imaging factors by Gustavo Rossanese Pinto, Guilherme Conforto Gracitelli, Fernando Cury Rezende, Claudio Gattas, Thais Cristina Pereira Vasques, Flavio Duarte Silva, Carlos Eduardo da Silveira Franciozi, Marcus Vinicius Malheiros Luzo

“…Results: The results showed a significant reduction in WOMAC and Visual Analog Scale scores for all evaluated times after VS compared to baseline. …”
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Virtual Reality and Sound Intervention under Chemotherapy (ViSu): study protocol for a three-arm randomised-controlled trial by Andre Karger, Luisa Ernsten, Steffen Holsteg, Nora K Schaal, Luisa M Keßling, Nele Schmutzler, Tanja N Fehm, Verena Friebe, Norbert Gattermann, Eugen Ruckhäberle

“…Virtual reality (VR) offers the potential to visually and audibly disengage from the surrounding environment and can create an alternative sense of presence. …”
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Acanthamoeba keratitis in a tertiary referral hospital in central China: demographics, risk factors, clinical presentation, treatments and outcomes by Jia-Song Wang, Dan Zhao, Tian-Yu Yao, Xiao-Ying Jiang, Hua-Tao Xie, Ming-Chang Zhang

“…AIM: To investigate the demographics, risk factors, clinical presentation, treatments and outcomes of Acanthamoeba keratitis (AK) in a tertiary referral hospital in central China. METHODS: In this noncomparative, retrospective study, a total of 21 AK patients were enrolled between April 2020 and March 2023. …”
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Exploring Molecular Pathways in Refractive Errors Associated with Inherited Retinal Dystrophies by Fabiana D’Esposito, Caterina Gagliano, Alessandro Avitabile, Giuseppe Gagliano, Mutali Musa, Matteo Capobianco, Federico Visalli, Edoardo Dammino, Marco Zeppieri, Maria Francesca Cordeiro

“…We also discuss the therapeutic implications of refractive defects in individuals with IRD, including possible approaches to treating visual impairments. In addition, we address the value of using cutting-edge imaging methods and animal models to examine refractive errors linked to IRDs and suggest future lines of inquiry for identifying new targets for treatment. …”
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Honey, Gellan Gum, and Hyaluronic Acid as Therapeutic Approaches for Skin Regeneration by Patrícia Sousa, Alicia Moreira, Bruna Lopes, Ana Catarina Sousa, André Coelho, Alexandra Rêma, Maria Balça, Luís Atayde, Carla Mendonça, Lucília P. da Silva, Cristiana Costa, Alexandra P. Marques, Irina Amorim, Rui Alvites, Filipa Batista, Filipa Mata, João Transmontano, Ana Colette Maurício

“…The formulations were designed to balance therapeutic efficacy with cost-effectiveness, leveraging low-cost raw materials and straightforward production methods.…”
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Pre-clinical safety studies of intranasal virus-like particles based vaccine for prevention of COVID-19 by Yana Y. Chernoryzh, Valeria M. Kondratieva, Аnastasia P. Malkova, Tatyana E. Savochkina, Olesya V. Eliseeva, Oleg E. Latyshev, Dmitriy Y. Yakunin, Olga N. Zaykova, Ekaterina S. Sludnyakova, Tatyana V. Grebennikova

“…The aim of the study is to conduct preclinical acute and subchronic toxicity studies assessing local tolerability of an intranasal VLP vaccine against COVID-19 in accordance with good laboratory practice. Materials and methods. Study was performed on adult outbreed mice (30 males, 30 females) and rats (45 males, 45 females). …”
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Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells by Tomokazu Fujimoto, Toshihiro Inoue, Saori Ohira, Nanako Awai-Kasaoka, Takanori Kameda, Miyuki Inoue-Mochita, Hidenobu Tanihara

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Meibomian Gland Dysfunction in Type 2 Diabetic Patients by Xiaolei Lin, Binbin Xu, Yuxi Zheng, Terry G. Coursey, Yinying Zhao, Junhua Li, Yana Fu, Xuewen Chen, Yun-e Zhao

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Optical coherence tomography angiography study on retinochoroidal thickness and blood flow changes after posterior scleral reinforcement surgery by Yongqi Mao, Hao Chen, Yunhua Tang, Haoming Geng, Fuwen Zhang

“…Purpose: Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery on the fundus structure and function in patients with high myopia. Methods: Retrospective clinical study. Forty cases (41eyes) of high myopia patients who underwent posterior scleral reinforcement surgery at Chengdu University of Traditional Chinese Medicine Affiliated Silver Eye Hospital from January 2022 to January 2025 were selected. …”
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