Population Pharmacokinetic Model for the Use of Intravenous or Subcutaneous Infliximab in Patients with Inflammatory Bowel Disease: Real-World Data from a Prospective Cohort Study by Joo Hye Song, Sung Noh Hong, Myeong Gyu Kim, Minjung Kim, Seong Kyung Kim, Eun Ran Kim, Dong Kyung Chang, Young-Ho Kim

“…Goodness-of-fit plots and visual predictive check were used to evaluate the PK model. …”
Get full text

A robust and effective framework for 3D scene reconstruction and high-quality rendering in nasal endoscopy surgery by Xueqin Ji, Xueqin Ji, Shuting Zhao, Shuting Zhao, Di Liu, Feng Wang, Xinrong Chen, Xinrong Chen

“…Although significant progress has been made in endoscopic 3D reconstruction methods, their application in nasal scenarios still faces numerous challenges. …”
Get full text

Adjacent, distal, or combination of point-selective effects of acupuncture on temporomandibular joint disorders: A randomized, single-blind, assessor-blind controlled trial by Kyung-Won Kang, Woo-Young Kim, Tae-Hun Kim, Byung-Cheul Shin, So-Young Jung, Ae-Ran Kim, Sun-Mi Choi

“…Background: The objectives of this study were to compare the efficacy of acupuncture among different types and to evaluate point-selective pain relief effects between selected adjacent or distant points in participants with temporomandibular joint disorders (TMDs). Methods: Forty-two participants were randomly allocated to three groups: an adjacent point selection group (Trt, n = 14), a distant point selection group (Con1, n = 14), or a combination group (Con2, n = 14). …”
Get full text

Clinical evaluation of 3D printed splint in the treatment of temporomandibular disorders by Yuanqing Ma, Weixu Li, Litong Li, Meng Cao, Chi Zhang

“…Abstract Objective To use a T-scan (Tekscan, Boston, USA) to evaluate the grinding effect of a three-dimensional (3D) printed occlusal splint and provide reference guidelines for adjusting occlusion and alleviating temporomandibular joint symptoms before orthodontic treatment. Methods Eighteen patients with temporomandibular disorder (TMD) were treated with 3D-printed stable occlusal plates for three months. …”
Get full text

Sensory Diet Program Through In-Person and Tele-Occupationa Therapy in Children with Autism Spectrum Disorder: A Single-Blind Randomized Controlled Trial by Simin Dehghani, Marzieh Pashmdarfard, Zahra Pashazadeh Azari, Alireza Akbarzadeh Baghban, Sima Dehghani, Navid Mirzakhani Araghi

“…Current research compared the effectiveness of the sensory diet program with and without teleoccupational therapy on sensory processing patterns, social competency and occupational performance in children with ASD. Materials and Methods: The study sample comprised 32 children with ASD 4-10 years old. …”
Get full text

Detailed Morphological Changes of Foveoschisis in Patient with X-Linked Retinoschisis Detected by SD-OCT and Adaptive Optics Fundus Camera by Keiichiro Akeo, Shuhei Kameya, Kiyoko Gocho, Daiki Kubota, Kunihiko Yamaki, Hiroshi Takahashi

“…To report the morphological and functional changes associated with a regression of foveoschisis in a patient with X-linked retinoschisis (XLRS). Methods. A 42-year-old man with XLRS underwent genetic analysis and detailed ophthalmic examinations. …”
Get full text

PDZ domains of PATJ facilitate immunological synapse formation to promote T cell activation by Xiaomin Zhang, Siyu Chen, Penghui Zhou, Danyang Wang, Liping Xu, Jingjing He, Wende Li, Xinxin Xiong, Ziqian Fang, Jianeng Zhang

“…In this study, we investigate the role of the PALS1-associated tight junction protein (PATJ), which contains 10 PDZ domains, in the formation of IS and its subsequent impact on T cell activation.Methods To elucidate the function of PATJ, we generated murine models with conditional T cell-specific knockout of Patj and assessed T cell activation both in vitro and in vivo within the context of infection and cancer. …”
Get full text

Worsening pain patterns and chronic post-surgical pain following total hip arthroplasty: A 6-month retrospective cohort study by Yusuke Suzuki, So Tanaka, Ryota Imai, Takeshi Chiba

“…Purpose: The aim of this study was to investigate chronic post-surgical pain (CPSP) in patients in the 6 months after total hip arthroplasty (THA), focusing on its prevalence, contributing factors, and duration. Methods: Study subjects were 257 women who underwent THA at a single hospital. …”
Get full text

Raman and FT-IR Spectroscopy Coupled with Machine Learning for the Discrimination of Different Vegetable Crop Seed Varieties by Stefan M. Kolašinac, Marko Mladenović, Ilinka Pećinar, Ivan Šoštarić, Viktor Nedović, Vladimir Miladinović, Zora P. Dajić Stevanović

“…Pre-processing was followed by Principal Component Analysis (PCA), and several classification methods were applied after that: the Support Vector Machines (SVM) algorithm, Partial Least Square Discriminant Analysis (PLS-DA), and Principal Component Analysis-Quadratic Discriminant Analysis (PCA-QDA). …”
Get full text

Phenotypic plasticity of metastatic melanoma by I. N. Mikhaylova, O. A. Аnurova, A. A. Lushnikova, I. V. Tsyganova, А. S. Senderovich, T. Т. Kondratieva, L. V. Demidov, N. N. Mazurenko

“…Rare cases of metastatic melanoma are known, that have no visual expression of melanocytic markers. Contradictory histology of such melanomas requires a differential diagnosis from morphologically similar non- melanocytic tumors, sarcoma or lymphoma. objective is to describe the extraordinary cases of metastatic melanomas with low expression of differentiation markers. material and methods. 15 melanoma cases with unusual clinical and morphological characteristics were included in the study. …”
Get full text

PILOT STUDY RESULTS OF THE INFLUENCE OF CITICOLINE AND PIRIBEDIL ON COGNITIVE FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE AFTER CORONARY ARTERY BYPASS SURGERY by M. M. Petrova, S. V. Prokopenko, O. V. Eremina, G. V. Matjushin, V. A. Sakovich, D. B. Drobot, E. Yu. Mozhejko, D. S. Kaskaeva

“…To reveal cognitive deficit after coronary artery bypass, the influence of citicoline, piribedil on the state of higher cerebral functions in the early and late periods after surgery.Material and methods. The study included 94 patients with ischemic heart disease. …”
Get full text

Integrating haptic simulation in dentistry: faculty insights and future directions by Danya Hashem, Abeer Farag, Abeer Farag, Amnah A. Algarni, Rania Zahran Mubarak, Nisreen Nabiel Hassan, Anfal Alqussier, Somaya Ali Saleh, Somaya Ali Saleh

“…PurposeEvaluate the knowledge of faculty members about haptic virtual reality simulation (HVRS) in dentistry and assess faculty members' perception towards the use of HVRS in dental education.MethodsThis interventional study involved distributing a questionnaire to 29 faculty members from different dental specialties as a baseline before attending a hands-on workshop on HVRS followed by another questionnaire distributed after the workshop. …”
Get full text

Reliability of an Inertial Measurement System Applied to the Technical Assessment of Forehand and Serve in Amateur Tennis Players by Lucio Caprioli, Cristian Romagnoli, Francesca Campoli, Saeid Edriss, Elvira Padua, Vincenzo Bonaiuto, Giuseppe Annino

“…Traditional methods for evaluating tennis technique, such as visual observation and video analysis, are often subjective and time consuming. …”
Get full text

Home-Based vs. Clinic-Based Rehabilitation After Joint Arthroplasty: A Prospective Matched Cohort Study by Erminia Cofano, Filippo Familiari, Tommaso Mori, Michele Mercurio, Andrea Vescio, Alessandro Giorgio, Giorgio Gasparini, Giuseppe Calafiore

“…This study aimed to compare CBR and HBR in terms of short-term post-operative functionality in patients who underwent THA and TKA. Methods: A prospective matched cohort study was performed on 120 patients who underwent primary THA and TKA; 60 patients underwent HBR, and 60 underwent CBR. …”
Get full text

Knowledge and confidence regarding pressure ulcer prevention among caregivers of high-risk individuals: A pre- and post-education assessment in a single-center by Maram T. Alkhatieb, Rahaf W. Shigdar, Zainab A. Alkhalifah, Hussain A. Alkhalifah, Hanan F. Alsabri, Lama W. Attar, Hana Z. Fatani, Haifa M. Alnahdi

“…Objective: We aimed to measure the effect of implementing a pressure ulcer (PU) educational program on the knowledge and confidence of caregivers taking care of bedridden patients or patients with limited mobility. Methods: This study included caregivers of immobile or bedridden patients in our center from 23 April 2023 to 13 May 2023. …”
Get full text

Efficacy and safety of the initial hypotensive treatment with an optimized latanoprost composition by S. Yu. Petrov, E. V. Yani, A. N. Zhuravleva, O. M. Filippova, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan, L. V. Vasilenkova, I. V. Manukyan

“…Purpose: a comparative study of the efficacy and safety of Latanoprost-Optic, a new composition of excipients and the original latanoprost, in the initial therapy of primary open-angle glaucoma (POAG)Material and methods. We performed a prospective, randomized, comparative study of 60 previously untreated patients (71 eyes) with early and advanced POAG stages. …”
Get full text

A Patch-Wise Mechanism for Enhancing Sparse Radar Echo Extrapolation in Precipitation Nowcasting by Yueting Wang, Hou Jiang, Tang Liu, Ling Yao, Chenghu Zhou

“…Although deep learning-based radar echo extrapolation methods are widely adopted, their effectiveness is limited by challenges in handling sparse echo sequences with low pixel proportions. …”
Get full text

Delimitation of Landslide Areas in Optical Remote Sensing Images Across Regions via Deep Transfer Learning by Zan Wang, Shengwen Qi, Yu Han, Bowen Zheng, Yu Zou, Yue Yang

“…Automatic delimitation of landslide areas empowered by deep learning methods has drawn tremendous attention in recent years. …”
Get full text

G-Protein-Coupled Estrogen Receptor (GPER) in Inflammatory Myopathies by Delia Righi, Diego Lopergolo, Nila Volpi, Daniela Franci, Paola Lorenzoni, Margherita Aglianò, Gianna Berti, Carlo Manco, Nicola De Stefano, Federica Ginanneschi

“…<b>Background/Objectives</b>: Given the multifaceted role of estrogen hormones in skeletal muscle pathophysiology and their well-established immunomodulatory properties, this study aimed to characterize the expression of the G-protein-coupled estrogen receptor (GPER) in patients with inflammatory myopathies (IM). <b>Methods</b>: Immunohistochemical analysis was performed on muscle biopsies from 13 patients with IM, 11 with non-inflammatory myopathies (N.IM), and 5control subjects. …”
Get full text

The role of thoracoscopic pneumonectomy in surgical treatment of lung diseases by V. A. Porkhanov, V. V. Danilov, V. B. Kononenko, N. V. Naryzhnyi, A. L. Kovalenko, V. V. Shtraub, V. A. Zhikharev

“…The objective was to estimate the immediate results of thoracoscopic pneumonectomies in various surgical lung diseases.Material and methods. Patients were divided into groups depending on the surgical access: thoracoscopy – group 1 (15 patients), thoracotomy – group 2 (30 patients). …”
Get full text