Efficacy and safety of faricimab for neovascular age-related macular degeneration: a systematic review and network meta-analysis by Francisco Rodríguez, Daniel Samacá-Samacá, Claudia Hernández-Castillo, Laura Prieto-Pinto, Carolina Sardi, Hugo Ocampo, Joshua Kock, Fabián Hernández

“…Objective To evaluate the efficacy and safety of faricimab compared with other anti-vascular endothelial growth factor (anti-VEGF) agents in treating neovascular age-related macular degeneration (nAMD) patients.Methods and analysis A systematic review (SR) was conducted up to January 2023. …”
Get full text

Efficacy of Cheiranthus Cheiri in the Treatment of Pericoronitis: A Double-blind, Randomized, Placebo-controlled Trial with Molecular Docking by Shubhamoy Ghosh, Aritra Roy Chowdhury, Sarbendu Paul, Avipsha Sarkar, Abhijit Rana, Mousumi Koley, Indrani Halder, Suman Chandra, Subhranil Saha

“…Subsequently, molecular docking of CC was performed to predict the binding affinity of ligands to receptor proteins. Materials and Methods: A 14-day, double-blind, randomized (2:1), placebo-controlled trial was undertaken at the Dental Outpatient Department of D. …”
Get full text

Intraocular pressure and ocular biomechanical parameters vary between generations of the ocular response analyzer in healthy and ectatic eyes by Phillip T. Yuhas, Maddison M. Fortman, Michael Nye, Ashraf M. Mahmoud, Cynthia J. Roberts, Cynthia J. Roberts

Get full text

Cervical transcutaneous vagal neuromodulation in chronic pancreatitis patients with chronic pain: A randomised sham controlled clinical trial. by Janusiya Anajan Muthulingam, Søren Schou Olesen, Tine Maria Hansen, Christina Brock, Asbjørn Mohr Drewes, Jens Brøndum Frøkjær

“…We investigated the pain-relieving effects of transcutaneous vagal nerve stimulation in comparison to sham treatment in chronic pancreatitis patients.<h4>Methods</h4>We conducted a randomised double-blinded, sham-controlled, crossover trial in patients with chronic pancreatitis. …”
Get full text

Life&amp;rsquo;s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening by Li W, Wen Y, Fan Y, Hu Z, Deng Z, Huang Q

“…After multivariate adjustment, the LC9 score was found to be inversely associated with COPD diagnosis. The RCS visually demonstrated a linear decreasing relationship between the two. …”
Get full text

Efficacy of Intravitreal Brolucizumab Switch in Pachychoroid Neovasculopathy by Nicolò Ribarich, Marco Battista, Lisa Checchin, Riccardo Sacconi, Francesco Bandello, Giuseppe Querques

“…Abstract Introduction This study aimed to evaluate the anatomical and functional outcomes of switching to intravitreally administered brolucizumab (Beovu®, Novartis) in patients affected by pachychoroid neovasculopathy (PNV) who were considered as non-responders to previous anti-vascular endothelial growth factor (anti-VEGF) therapies, defined as the persistence of intraretinal fluid (IRF), subretinal fluid (SRF), or subretinal hyper-reflective material (SHRM). Methods Twenty-three eyes of 21 patients with exudative PNV, who were switched to brolucizumab between April 2021 and December 2023, were retrospectively enrolled. …”
Get full text

Crisis versus extended care: bimodal distribution of length of stay in psychiatric inpatients by Andreas B. Hofmann, Tobias R. Spiller, Jeremy A. Rapaport, Philipp Homan, Erich Seifritz, Stefan Vetter, Stephan T. Egger, Achim Burrer

“…While previous research has established that LoS distributions are typically right-skewed across medical specialties, detailed characterizations of these distributions within psychiatric settings remain limited, particularly regarding variations across diagnostic categories. Methods We conducted a retrospective cross-sectional analysis of 17,687 psychiatric hospitalizations at the University Hospital of Psychiatry Zurich between 2013 and 2020. …”
Get full text

Evaluation of a Bayesian Belief Network tool for translating science and informing policy: the case of antibiotic misuse in Tanzania by Miss Madeleine Clarkson, Dr Katherine L Keenan, Dr Edward Lavender, Prof Stephen E Mshana, Dr Martha F Mushi, Prof Matthew TG Holden, Dr V Anne Smith

“…To assess BNNs’ capacity to live up to this promise, we make a previously derived BBN for antibiotic misuse into a web-based interactive tool and evaluated it with non-specialists. Methods: A BBN of determinants of antibiotic misuse in Tanzanian urinary tract infection patients was incorporated into a web-based application, which included an interactive tool plus other relevant information, such as educational materials. …”
Get full text

Efficacy and Safety of Ophthalmic Steroids in the Management of Polypoidal Choroidal Vasculopathy: A Systematic Review by Adriono GA, Triyoga IF, Kadharusman MM, Victor AA, Djatikusumo A, Yudantha AR, Hutapea MM

“…Gitalisa Andayani Adriono,1,2,&ast; Ichsan Fauzi Triyoga,3,&ast; Marcello Mikhael Kadharusman,3,&ast; Andi Arus Victor,1 Ari Djatikusumo,1 Anggun Rama Yudantha,1 Mario Marbungaran Hutapea1 1Department of Ophthalmology, Kirana Eye Centre - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; 2JEC Eye Hospitals and Clinics, Jakarta, Indonesia; 3Faculty of Medicine, University of Indonesia, Jakarta, Indonesia&ast;These authors contributed equally to this workCorrespondence: Gitalisa Andayani Adriono, Department of Ophthalmology, Kirana Eye Centre - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Kimia Street, Jakarta, 10320, Indonesia, Tel +62 811 131 660, Email gitalisa.andayani@ui.ac.idPurpose: This review aims to clarify the role of ophthalmic steroids in polypoidal choroidal vasculopathy (PCV) treatment.Methods: A systematic literature search was performed using Scopus, PubMed, MEDLINE, Cochrane, ProQuest, and manual searches. …”
Get full text

Survey of Glaucoma Practice Patterns Among Members of The Philippine Glaucoma Society by Edgar Felipe U. Leuenberger, MD, DPBO, James Paul S. Gomez, MD, DPBO, Karlo Paolo L. Alejo, MD, DPBO, Robert Edward T. Ang, MD, DPBO, Maria Zita Zagala-Meriales, MD, DPBO, Pamela C. Allarey, MD, DPBO, Aldo Mar B. Cariaga, MD, DPBO, John Mark S. De Leon, MD, DPBO, Sammy L. Ang, MD, DPBO

“…Objective: To identify the glaucoma clinical practice patterns among the members of the Philippine Glaucoma Society (PGS) from 2015 to 2016 using an online survey. Methods: An online link was sent to each consenting PGS member which directed them to two poll sites. …”
Get full text

UAV-OVD: Open-Vocabulary Object Detection in UAV Imagery via Multi-Level Text-Guided Decoding by Lijie Tao, Guoting Wei, Zhuo Wang, Zhaoshuai Qi, Ying Li, Haokui Zhang

“…Although the majority of existing methods are developed under closed-set assumptions, and some recent studies have begun to explore open-vocabulary or open-world detection, their application to UAV imagery remains limited and underexplored. …”
Get full text

The Use of Large Language Models and Their Association With Enhanced Impact in Biomedical Research and Beyond by Huzi Cheng, Wen Shi, Bin Sheng, Aaron Y. Lee, Josip Car, Varun Chaudhary, Atanas G. Atanasov, Nan Liu, Yue Qiu, Qingyu Chen, Tien Yin Wong, Yih‐Chung Tham, Ying‐Feng Zheng

Get full text

Incidence and Risk Factors for Femoral Malrotation Following Intramedullary Nailing of Trochanteric Fractures: A CT-Based Analysis by Chao Han M.D, Xiao-dan Li M.D, Zhe Han M.D, Qiang Dong M.D

“…Objective To quantify rotational displacement following intramedullary nail fixation for intertrochanteric femoral fractures using three-dimensional (3D) CT imaging, analyze associated risk factors, and evaluate its clinical significance. Methods This study enrolled a cohort of 252 patients who underwent intramedullary nail fixation for intertrochanteric femoral fractures between 2019 and 2023. …”
Get full text

Multimodal Digital Learning and Local Indigenous Frameworks to Enhance Critical Thinking in History Learning by Suci Rahayu, Sariyatun Sariyatun, Leo Agung Sutimin, Deny Tri Ardianto

“… Background: Critical thinking is fundamental to teaching history, yet student analysis is often limited by traditional methods that rely primarily on lecture. Using local Indigenous history in context and accessing multimodal digital materials enhances the learning experience and encourages active thinking at a higher level. …”
Get full text

Preliminary insights into serum metabolomics in atrophic myopic maculopathy: potential link to fatty acid metabolism dysregulation by Yuanyuan Fan, Bintao Xie, Lifeng Chen, Mengai Wu, Li Lin, Zhijie Wang, Bin Zheng

“…This study compared serum metabolite profiles between patients with high myopia with and without AMM. Methods: This case–control study included 57 adults with high myopia (30 with AMM, 27 without AMM). …”
Get full text

Assessment of Relationship between Neovascularization Type Using Wide Field Optical Coherence Tomography Angiography in Eyes with Proliferative Diabetic Retinopathy by Akshita Aggarwal, Dibya Prabha, Brijesh Takkar, Sobha Sivaprasad, Padmaja Kumari Rani

“…This study aims to classify retinal neovascularization into subtypes and assess their correlation with ischemic index using widefield optical coherence tomography (OCT) angiography. Methods This retrospective observational study included 50 treatment-naïve patients (84 eyes) with PDR who underwent baseline widefield fundus photography (CLARUS 500™) and widefield optical coherence tomography angiography (WF-OCTA; Plex Elite 9000) between January 2022 and June 2024. …”
Get full text

Histological study of potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazole-3-yl)thio)acetate (PKR-173) corrective influence on the chickens liver state in the condition of... by R. O. Shcherbyna, Ye. V. Vashchyk

“…The aim is histological study of the compound of potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate (PKR-173) corrective influence on the chickens liver under tetracycline hepatitis condition. Materials and methods. As an object of research potassium 2-((4-amino-5- (morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio) acetate was used which is a water-soluble compound. …”
Get full text

The Relationship Between Preferred Learning Styles and Academic Achievement of Undergraduate Health Sciences Students Compared to Other Disciplines at a Middle Eastern University U... by Gangadharan S, Al Mezeini K, Gnanamuthu SS, Al Marshoudi KA

“…Visual learners prefer observing; Aural learners favor listening to lectures; Reading/Writing learners engage through texts and notes; Kinesthetic learners benefit from tactile activities.Purpose: To compare learning style preferences of undergraduate health sciences students with other disciplines and examine the relationship between VARK scores and academic performance.Methods: A cross-sectional study of 347 undergraduate students recorded demographic data and responses to the Arabic version of the VARK questionnaire. …”
Get full text

Immunological parameters of maternal peripheral blood as predictors of future pregnancy outcomes in patients with unexplained recurrent pregnancy loss by Yingrong Li, Irene X. Y. Wu, Xuan Wang, Jinlu Song, Quan Chen, Weiru Zhang

“…Additionally, models were visualized by constructing dynamic and static nomograms. …”
Get full text

Efficacy and safety of intracameral betamethasone versus dexamethasone at the end of phacoemulsification by Amira F.Z. El Hewehi, Khaled G. Abu Eleinen, Sherif A. Eissa, Moataz H. Osman

“…Purpose The current study aimed to determine the safety and efficacy of intracameral injection of betamethasone or dexamethasone at the end of phacoemulsification in decreasing postoperative inflammation. Patients and methods This is a comparative, prospective, interventional, randomized study that was carried out at Cairo University Hospital, Cairo, Egypt. …”
Get full text