Diagnostic precision, safety, and patient experience of the freehand transperineal prostate biopsy technique under local anesthesia – A single-center experience by Aikaterini Eleftheriadou, Charlotte Collins, Dilaaniy Kannapiran, Faria Antara, Moustafa Elhammadi, Sarosh Janardanan, Michael Mikail, Nimalan Arumainayagam, Danny Darlington Carbin

“…We aim to assess the pain tolerability, diagnostic value, and safety of the totally freehand LATP (tF-LATP) technique. Methods: Patients undergoing tF-LATP for suspected prostate cancer (PCa) from February 2024 to June 2024 were prospectively included. …”
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Exploring the Application of Neurostructural Principles to the Design of Public Spaces on University Campuses by Qihang Zhou, Xingxing Fang

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Integrating AI into ADHD Therapy: Insights from ChatGPT-4o and Robotic Assistants by Santiago Berrezueta-Guzman, Mohanad Kandil, Stefan Wagner

“…Additionally, most current methods lack multi-modal interaction, limiting their ability to engage children effectively across speech, text, and visual feedback. …”
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“A Correlation Study of Core Muscle Strength with Rectus Femoris Flexibility in Obese and Nonobese Patients with Knee Osteoarthritis”: An Observational Study by Manalisa Kalita, Sunita Sharma

“…Settings and Design: MMIPR orthopedics outpatient department and cross-sectional study were conducted. Subjects and Methods: Participants aged 40–70 meeting inclusion/exclusion criteria were selected (n = 51). …”
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The Impact of Subject Age, Gender, and Arch Length on Attitudes of Syrian Dentists towards Shortened Dental Arches by Mohammad Zakaria Nassani, Tammam Ibrahim Al-Nahhal, Omar Kujan, Bassel Tarakji, Elizabeth Jane Kay

“…This study aimed to investigate the impact of subject age, gender, and arch length on dentists’ attitudes towards unrestored shortened dental arches. Materials and Methods. 93 Syrian dentists were interviewed and presented with 24 scenarios for male and female subjects of different ages and shortened dental arches of varying length. …”
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Autistic traits in women with primary dysmenorrhea: a case–control study by Toy H, Herguner A, Simsek S, Herguner S

“…In this study, we investigated the autistic traits in female university students with primary dysmenorrhea (PD). Methods: Seventy females with PD and 70 females without PD were enrolled in the study. …”
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Treatment of multilevel cervical disc disease with standalone cervical cages with or without anterior plating: A prospective randomized comparative study by Mahmoud Abousayed, Yasser Elmiligui, Wael Koptan, Mostafa Elhamaky, Ahmed Samir Barakat, Ahmed Maher Sultan

“…Internal fixation using anterior cervical plate has been developed as an adjunct to ACDF to enhance the stability provided by the intervertebral cages. Patients and Methods: A total number of 60 consecutive patients diagnosed with multilevel cervical disc disease (two or more) underwent ACDF with or without additional anterior plating, between August 2021 and March 2022. …”
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The Problem of Emotional Well-Being and Sleep Disorders among Patients of the Neurosurgery Ward – Preliminary Research by Renata Jabłońska, Filip Lisowski, Paweł Sokal

“…Assessment of pain, emotional state and sleep disorers among patients of the neurosurgery department. Material and Methods. The study was conducted among 63 neurosurgery patients. …”
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Digital Twin-Based and Knowledge Graph-Enhanced Emergency Response in Urban Infrastructure Construction by Chao Chen, Yanyun Lu, Bo Wu, Linhai Lu

“…Traditional risk assessment methods often rely on static models and experience-based decision-making, limiting their ability to adapt to dynamic construction conditions. …”
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Posterior Vitreous Detachment in Healthy Versus AMD Eyes Assessed by Widefield Optical Coherence Tomography by Maciej Gawęcki, Krzysztof Kiciński, Andrzej Grzybowski, Sławomir Teper

“…Additionally, the retinal thicknesses in the central and peripheral zones of AMD patients and the control group were compared. <b>Methods:</b> We included 123 eyes from 83 participants with dry AMD, 123 from 87 participants with wet AMD, and 85 from 53 healthy controls. …”
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Effects of Preoperative Oral Carbohydrate on Perioperative Maternal Outcomes Undergoing Cesarean Section: A Systematic Review and Meta-Analysis by Haibin Shi, Caihong Zheng, Bin Zhu

“…This meta-analysis was conducted to evaluate the efficacy of preoperative oral CHO in elective cesarean section. Methods. PubMed, Embase, Web of Science, and the Cochrane Library were searched from inception to July 2023. …”
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THE ASSESSMENT OF NICORANDIL EFFECT ON THE QUALITY OF LIFE IN PATIENTS WITH STABLE ANGINA IN THE "KVAZAR" STUDY by S. Yu. Martsevich, N. P. Kutishenko, A. D. Deev

“…To assess the effect of nicorandil added to the standard therapy of patients with stable ischemic heart disease (IHD) on the quality of life (QoL).Material and methods. Patients with verified IHD (stable angina; n=120) were included into double-blind, placebo-controlled, parallel group study. …”
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M01 tool: an automated, comprehensive computational tool for generating small molecule-peptide hybrids and docking them into curated protein structures by Mahsa Sheikholeslami, Mohammad Hasan Nazari, Afshin Fassihi

“…Abstract Background The field of computational drug design is undergoing rapid advancements, highlighting the need for innovative methods to enhance the efficiency and accuracy of calculating ligand-receptor interactions. …”
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Clinicodemographic profile of VKC patients in tertiary care centre of North India: A prospective study by Manpreet Kaur, Malvika Sharma, Nancy Sharma

“…Objective: To know the demography and clinical profile of patients of vernal keratoconjunctivitis (VKC) in a tertiary care center over a period of 6 months from April 2023 to September 2023. Methods: A prospective, hospital-based study including a total of 250 patients with Vernal Keratoconjunctivitis (VKC) studied from April 2023 to September 2023 in a tertiary care center in north India. …”
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Medical VR Simulator for Pediatric Strabismus Treatment by Artem Obukhov, Elena Kutimova, Julia Matrosova, Daniil Teselkin, Maxim Shilcin

“…The specifics of the realization of ophthalmic exercises for the virtual simulator and the methods for evaluation of the quality of their performance are considered. …”
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Effects of different topical anesthetics on pain from needle insertion and injection, and the influence of anxiety in patients awaiting endodontic treatment by Fatih Aksoy, Samet Tosun

“…ObjectivesThis study aimed to evaluate the effects of 5% lidocaine and 2.5% lidocaine/2.5% prilocaine topical anesthetic on pain during needle insertion and infiltration injection in the labial mucosa of anterior maxillary teeth, and to assess the relationship between patients’ anxiety and pain scores.Materials and MethodsThe Modified Dental Anxiety Scale questionnaire was applied and recorded. …”
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Clinical Outcomes of All-Inside Arthroscopic Lateral Ankle Ligament Reconstruction for Chronic Lateral Ankle Instability: A Prospective Series with Minimum 12 Month Outcomes by Thomas L. Lewis BSc (Hons) MBChB (Hons) FRCS (Tr&Orth) MFSTEd, Vikram Vignaraja MBBS BSc (Hons) MRCS, Samuel Franklin MBBCh (Hons) MRCS, Gabriel Ferreira MD MSc PhD, Gustavo Araujo Nunes MD, Peter Lam MBBS (Hons), FRACS, FAOA, Robbie Ray MBChB, ChM(T&O), FRCSed(Tr&Orth), FEBOT

“…Methods: This prospective series included 36 consecutive patients who underwent isolated arthroscopic lateral ligament reconstruction for CAI between November 2020 and November 2022 with minimum 12-month follow up. …”
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The Impact of Individual Factors on Careless Responding Across Different Mental Disorder Screenings: Cross-Sectional Study by Huawei Kuang, Lichao Zhu, Haonan Yin, Zihe Zhang, Biao Jing, Junwei Kuang

“…In addition, response times were visualized to identify patterns between careless and careful responders. …”
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INSTITUTIONAL CHANGES IN THE SOCIO-ECONOMIC LIFE OF SOCIETY ON THE BASIS OF DIGITAL INCLUSION AND SECURITY by K.M. Kraus

“…In order to achieve the goal, analysis and synthesis, generalization and comparison, graphic and statistical methods were used, which in the complex made it possible to present scientific developments in an argumentative manner, which will be useful for both theoreticians and practitioners. …”
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Establishment of a nomogram model for predicting the risk of contrast-induced nephropathy after percutaneous coronary intervention in type 2 diabetics by Gu Li, Shi Yun-tao, Xue Song

“…Objective To explore the risk factors of contrast-induced nephropathy（CIN）in patients with type 2 diabetes mellitus（T2 DM）undergoing percutaneous coronary intervention（PCI）and develop a visualized evaluation tool for clinical prediction of CIN.Methods A total of 625 T2 DM patients fulfilling the criteria were selected and divided into control（n=546）and CIN（n=79）groups.Clinical data related to CIN were collected.Statistically significant variables were imported into a multivariate Logistic regression model for analyzing the risk factors of CIN.R-software was utilized for developing a nomogram model for predicting CIN risk.Receiver operating characteristic（ROC）curve was plotted for testifying the predictive value and conformance testing was performed by plotting calibration curve.Hosmer-Lemeshow test was utilized for judging the model’s goodness-of-fit.Results Age, hypertension, hemoglobin<130 g/L,albumin<30 g/L,LEVF<50%,uric acid>400 μmol/L and eGFR<90 mL·min^-1·（1.73 m²）^-1 were independent risk factors for T2 DM complicated with post-PCI CIN（all P<0.05）.With an inclusion of these factors, a nomogram model was successfully constructed.It had decent prediction performance with an area under the ROC curve of 0.82（95% CI=0.802 to 0.882）.Calibration curve indicated an excellent correlation between predicted and actual results（P=0.278）.Conclusion The above individualized nomogram model for predicting the risk of CIN patients has an excellent resolution.It has guiding significance for screening high-risk population with CIN among T2 DM patients undergoing PCI and formulating intervention strategies.…”
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